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Madrigal Pharmaceuticals, Inc.

MDGL
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001157601

In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 3 sales; 414 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Madrigal Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
305
−13 vs. Q1 2025
Shares held
23.6M
−153.6K (−0.6%) vs. Q1 2025
Total value
$7.13B
−$716.5M (−9.1%) vs. Q1 2025
New holders
38
107 more added
Sold out
51
110 more reduced

3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MDGL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 305 institutions
Q1 2021: 137 institutionsQ2 2021: 151 institutionsQ3 2021: 133 institutionsQ4 2021: 144 institutionsQ1 2022: 140 institutionsQ2 2022: 138 institutionsQ3 2022: 135 institutionsQ4 2022: 189 institutionsQ1 2023: 223 institutionsQ2 2023: 208 institutionsQ3 2023: 206 institutionsQ4 2023: 226 institutionsQ1 2024: 266 institutionsQ2 2024: 257 institutionsQ3 2024: 257 institutionsQ4 2024: 283 institutionsQ1 2025: 321 institutionsQ2 2025: 305 institutionsQ3 2025: 352 institutionsQ4 2025: 387 institutionsQ1 2026: 380 institutionsQ2 2026: 414 institutions
Value heldQ2 2025: $7.13B
Q1 2021: $1.43BQ2 2021: $1.09BQ3 2021: $876.5MQ4 2021: $1.01BQ1 2022: $1.20BQ2 2022: $857.7MQ3 2022: $763.2MQ4 2022: $3.86BQ1 2023: $3.36BQ2 2023: $3.43BQ3 2023: $2.54BQ4 2023: $4.57BQ1 2024: $5.64BQ2 2024: $6.41BQ3 2024: $4.77BQ4 2024: $7.08BQ1 2025: $7.85BQ2 2025: $7.13BQ3 2025: $10.7BQ4 2025: $13.7BQ1 2026: $12.4BQ2 2026: $12.7B
Institutions holding MDGL and their total value by quarter
QuarterHoldersValue
Q2 2026414$12.7B
Q1 2026380$12.4B
Q4 2025387$13.7B
Q3 2025352$10.7B
Q2 2025305$7.13B
Q1 2025321$7.85B
Q4 2024283$7.08B
Q3 2024257$4.77B
Q2 2024257$6.41B
Q1 2024266$5.64B
Q4 2023226$4.57B
Q3 2023206$2.54B
Q2 2023208$3.43B
Q1 2023223$3.36B
Q4 2022189$3.86B
Q3 2022135$763.2M
Q2 2022138$857.7M
Q1 2022140$1.20B
Q4 2021144$1.01B
Q3 2021133$876.5M
Q2 2021151$1.09B
Q1 2021137$1.43B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Madrigal Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding MDGL in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Janus Henderson Group PLC2,191,753$663.3M0.33%−14,096−0.6%Reduced
Paulson & Co. Inc.2,089,523$632.4M31.44%−10,000−0.5%Reduced
RTW Investments, LP1,993,687$603.4M8.59%00.0%Unchanged
Baker Bros. Advisors LP1,976,018$598.0M5.80%+1,428+0.1%Added
Vanguard Group Inc1,877,281$568.1M0.01%+187,170+11.1%Added
Avoro Capital Advisors LLC1,875,000$567.5M9.94%−147,222−7.3%Reduced
BlackRock, Inc.1,438,724$435.4M0.01%−47,736−3.2%Reduced
State Street Corp690,715$209.0M0.01%−67,796−8.9%Reduced
Price T Rowe Associates Inc508,464$153.9M0.02%−34,169−6.3%Reduced
UBS Group AG505,714$153.0M0.03%+184,207+57.3%Added
FMR LLC445,339$134.8M0.01%−206,760−31.7%Reduced
Geode Capital Management, LLC414,392$125.4M0.01%−6,483−1.5%Reduced
Adage Capital Partners GP, L.L.C.376,163$113.8M0.19%+184,554+96.3%Added
William Blair Investment Management, LLC350,289$106.0M0.28%−2,866−0.8%Reduced
Bank of America Corp277,221$83.9M0.01%+31,260+12.7%Added
Morgan Stanley247,962$75.0M0.00%−136,866−35.6%Reduced
Hood River Capital Management LLC244,738$74.1M1.03%+744+0.3%Added
Polar Capital Holdings Plc225,410$68.2M0.36%+75,190+50.1%Added
Pictet Asset Management Holding SA208,266$63.0M0.06%+1,223+0.6%Added
Citadel Advisors LLC207,339$62.7M0.05%+206,538+25,785.0%Added
Artisan Partners Limited Partnership201,571$61.0M0.09%+63,833+46.3%Added
Erste Asset Management GmbH201,100$60.8M0.51%+36,700+22.3%Added
Invesco Ltd.200,356$60.6M0.01%+67,422+50.7%Added
Goldman Sachs Group Inc189,840$57.5M0.01%+201+0.1%Added
Norges Bank176,467$53.4M0.01%+82,470+87.7%Added
American Century Companies Inc167,784$50.8M0.03%+9,478+6.0%Added
Woodline Partners LP159,623$48.3M0.26%−157,810−49.7%Reduced
Charles Schwab Investment Management Inc153,085$46.3M0.01%+1,834+1.2%Added
ArrowMark Colorado Holdings LLC144,808$43.8M0.79%−35,301−19.6%Reduced
Northern Trust Corp142,868$43.2M0.01%−8,018−5.3%Reduced
Rock Springs Capital Management LP140,296$42.5M2.65%−26,402−15.8%Reduced
Fiera Capital Corp130,622$39.5M0.13%−1,557−1.2%Reduced
Armistice Capital, LLC124,000$37.5M1.42%−11,883−8.7%Reduced
Tao Capital Management LP112,785$34.1M25.03%00.0%Unchanged
D. E. Shaw & Co., Inc.111,981$33.9M0.03%+12,975+13.1%Added
Point72 Asset Management, L.P.110,877$33.6M0.08%+45,017+68.4%Added
MPM Oncology Impact Management LP100,415$30.4M5.27%00.0%Unchanged
Susquehanna International Group, LLP100,322$30.4M0.05%−42,321−29.7%Reduced
Connor, Clark & Lunn Investment Management Ltd.100,095$30.3M0.11%−2,265−2.2%Reduced
Tri Locum Partners LP97,765$29.6M8.98%+59,896+158.2%Added
Bank of New York Mellon Corp88,943$26.9M0.01%+28,154+46.3%Added
Lord, Abbett & Co. LLC84,217$25.5M0.08%−33,807−28.6%Reduced
Affinity Asset Advisors, LLC80,000$24.2M3.58%00.0%Unchanged
EcoR1 Capital, LLC75,000$22.7M1.35%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.70,559$21.4M0.07%+218+0.3%Added
BNP Paribas Arbitrage, SA69,037$20.9M0.02%+65,561+1,886.1%Added
Barclays PLC62,674$19.0M0.01%+15,803+33.7%Added
New York State Common Retirement Fund61,062$18.5M0.02%+16,291+36.4%Added
Braidwell LP60,781$18.4M0.63%+12,091+24.8%Added
Franklin Resources Inc60,715$18.4M0.00%+41,762+220.3%Added
JPMorgan Chase & Co55,854$16.9M0.00%+27,840+99.4%Added
Marshall Wace, LLP55,119$16.7M0.02%+52,319+1,868.5%Added
Raymond James Financial Inc54,933$16.6M0.01%+1,017+1.9%Added
Emerald Advisers, LLC53,108$16.1M0.59%+5,199+10.9%Added
StemPoint Capital LP52,694$15.9M5.13%+11,758+28.7%Added
Voya Investment Management LLC51,090$15.5M0.02%+41,656+441.6%Added
Logos Global Management LP50,000$15.1M2.02%+50,000New
Candriam Luxembourg S.C.A.49,965$15.1M0.09%+28,593+133.8%Added
Ensign Peak Advisors, Inc48,399$14.6M0.03%00.0%Unchanged
University of Wisconsin Foundation48,376$14.6M16.38%00.0%Unchanged
Rheos Capital Works Inc.43,215$13.1M0.75%00.0%Unchanged
Nuveen, LLC41,533$12.6M0.00%−8,389−16.8%Reduced
Groupama Asset Managment40,891$12.3M0.20%+7,439+22.2%Added
UBS Asset Management Americas Inc39,809$12.0M0.00%+13,446+51.0%Added
Emerald Mutual Fund Advisers Trust36,920$11.2M0.68%+1,682+4.8%Added
Wells Fargo & Company36,669$11.1M0.00%−422−1.1%Reduced
Balyasny Asset Management LLC34,500$10.4M0.02%+7,285+26.8%Added
Russell Investments Group, Ltd.34,015$10.3M0.01%+4,441+15.0%Added
Schroder Investment Management Group33,207$10.0M0.01%+2,801+9.2%Added
Gilder Gagnon Howe & Co LLC31,553$9.55M0.10%−103−0.3%Reduced
EULAV Asset Management31,000$9.38M0.22%+21,000+210.0%Added
California Public Employees Retirement System27,583$8.35M0.01%+30.0%Added
Swiss National Bank27,400$8.29M0.00%+2,000+7.9%Added
Rhumbline Advisers26,363$7.98M0.01%−10.0%Reduced
683 Capital Management, LLC24,865$7.53M0.76%+1,289+5.5%Added
Rafferty Asset Management, LLC24,533$7.42M0.02%−5,369−18.0%Reduced
Deutsche Bank AG24,115$7.30M0.00%−1,825−7.0%Reduced
Manufacturers Life Insurance Company, The23,416$7.09M0.01%+471+2.1%Added
TD Asset Management Inc23,240$7.03M0.01%+1,000+4.5%Added
Legal & General Group Plc23,109$6.99M0.00%+8,612+59.4%Added
Alliancebernstein L.P.21,250$6.43M0.00%−2,205−9.4%Reduced
Macquarie Group Ltd19,643$5.95M0.01%+4,643+31.0%Added
Avidity Partners Management LP19,000$5.75M1.15%+19,000New
Citigroup Inc18,483$5.59M0.00%−28,736−60.9%Reduced
Rockefeller Capital Management L.P.17,948$5.43M0.01%+339+1.9%Added
SEI Investments Co17,542$5.31M0.01%+1,547+9.7%Added
Kornitzer Capital Management Inc14,760$4.47M0.09%00.0%Unchanged
Envestnet Asset Management Inc14,502$4.39M0.00%−768−5.0%Reduced
California State Teachers Retirement System14,133$4.28M0.00%+1,777+14.4%Added
LPL Financial LLC14,121$4.27M0.00%−16,701−54.2%Reduced
Journey Strategic Wealth LLC13,078$3.96M0.13%00.0%Unchanged
Hennion & Walsh Asset Management, Inc.12,675$3.84M0.15%+1,666+15.1%Added
Mirae Asset Global ETFs Holdings Ltd.12,489$3.78M0.01%−1,369−9.9%Reduced
Mutual of America Capital Management LLC12,309$3.73M0.04%+1,046+9.3%Added
Nan Fung Group Holdings Ltd11,872$3.59M5.66%00.0%Unchanged
Renaissance Technologies LLC10,836$3.28M0.00%−74,250−87.3%Reduced
Millennium Management LLC10,835$3.28M0.00%+8,328+332.2%Added
MetLife Investment Management10,062$3.05M0.02%−391−3.7%Reduced
Royal Bank of Canada9,603$2.91M0.00%+784+8.9%Added
Algert Global LLC9,530$2.88M0.06%−240−2.5%Reduced