Madrigal Pharmaceuticals, Inc.
MDGL- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001157601
In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 1 open-market purchase and 3 sales; 416 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.
Holders of 5% or more of MDGL
Holders whose latest Schedule 13D or 13G filing reports 5% or more of Madrigal Pharmaceuticals, Inc., largest stake first. The change is against the holder's previous filing.
| Holder | Latest form | Stake | Change | First filed | Latest filing | Filing |
|---|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 13D/A | 9.99%2.33M shares | – | Feb 16, 20218 filings | Nov 6, 2026 | SEC |
| Janus Henderson Group PLC | 13G/A | 8.80%2.02M shares | +1.80 ppfrom 7.00% | Sep 8, 202310 filings | May 15, 2026 | SEC |
| Taub Rebecca | 13D/A | 7.80%1.81M shares | – | Dec 12, 20251 filing | Dec 12, 2025 | SEC |
| Friedman Paul A | 13D/A | 7.80%1.81M shares | – | Dec 12, 20251 filing | Dec 12, 2025 | SEC |
| Paulson & Co. Inc. | 13G/A | 6.10%1.39M shares | −1.40 ppfrom 7.50% | Nov 13, 20235 filings | May 15, 2026 | SEC |
Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.
13D and 13G filings
56 Schedule 13D and 13G filings on Madrigal Pharmaceuticals, Inc., newest first, including old-format filings without a stake.
| Filed (ET) | Filer | Form | Stake | Change | Event date | Filing |
|---|---|---|---|---|---|---|
| Nov 6, 20266:15 PM ET | Baker Bros. Advisors LPand 3 others | 13D/A | 9.99%2.33M shares | – | Nov 6, 2026 | SEC |
| Jul 29, 20263:19 PM ET | BlackRock, Inc. | 13G/A | 4.60%1.07M shares | –Below 5% | Jun 30, 2026 | SEC |
| May 15, 20264:43 PM ET | Paulson & Co. Inc. | 13G/A | 6.10%1.39M shares | −1.40 ppfrom 7.50% | Mar 31, 2026 | SEC |
| May 15, 202612:37 PM ET | Janus Henderson Group PLC | 13G/A | 8.80%2.02M shares | +1.80 ppfrom 7.00% | Mar 31, 2026 | SEC |
| Mar 27, 202610:34 AM ET | Vanguard Group Inc | 13G/A | 0.00%0 shares | –Below 5% | Mar 13, 2026 | SEC |
| Feb 17, 20265:19 PM ET | Paulson & Co. Inc. | 13G/A | 7.50%1.71M shares | – | Dec 31, 2025 | SEC |
| Feb 17, 20264:34 PM ET | Janus Henderson Group PLC | 13G/A | 7.00%1.58M shares | −1.30 ppfrom 8.30% | Dec 31, 2025 | SEC |
| Dec 12, 20256:10 PM ET | Taub Rebecca | 13D/A | 7.80%1.81M shares | – | Dec 10, 2025 | SEC |
| Dec 12, 20256:10 PM ET | Friedman Paul A | 13D/A | 7.80%1.81M shares | – | Dec 10, 2025 | SEC |
| Nov 14, 202512:06 PM ET | Janus Henderson Group PLC | 13G/A | 8.30%1.84M shares | −1.60 ppfrom 9.90% | Sep 30, 2025 | SEC |
| Aug 14, 202511:24 AM ET | Janus Henderson Group PLC | 13G/A | 9.90%2.19M shares | −0.10 ppfrom 10.00% | Jun 30, 2025 | SEC |
| May 14, 202512:15 PM ET | Janus Henderson Group PLC | 13G/A | 10.00%2.21M shares | −0.10 ppfrom 10.10% | Mar 31, 2025 | SEC |
| Feb 14, 202512:10 PM ET | Janus Henderson Group PLC | 13G/A | 10.10%2.21M shares | – | Dec 31, 2024 | SEC |
| Nov 14, 2024 | Janus Henderson Group PLC | 13G/AOld format | – | – | – | SEC |
| Nov 14, 2024 | Paulson & Co. Inc. | 13G/AOld format | – | – | – | SEC |
| Nov 14, 2024 | RTW Investments, LP | 13GOld format | – | New | – | SEC |
| Mar 25, 2024 | Baker Bros. Advisors LP | 13D/AOld format | – | – | – | SEC |
| Feb 14, 2024 | Armistice Capital, LLC | 13G/AOld format | – | – | – | SEC |
| Feb 14, 2024 | Paulson & Co. Inc. | 13G/AOld format | – | – | – | SEC |
| Feb 14, 2024 | Avoro Capital Advisors LLC | 13G/AOld format | – | – | – | SEC |
| Feb 13, 2024 | Janus Henderson Group PLC | 13G/AOld format | – | – | – | SEC |
| Feb 13, 2024 | Vanguard Group Inc | 13G/AOld format | – | – | – | SEC |
| Jan 29, 20245:25 PM ET | BlackRock Inc. | 13G/AOld format | – | – | – | SEC |
| Jan 22, 2024 | State Street Corp | 13G/AOld format | – | – | – | SEC |
| Dec 13, 2023 | Bay City Capital LLC | 13D/AOld format | – | – | – | SEC |
| Nov 21, 2023 | Baker Bros. Advisors LP | 13D/AOld format | – | – | – | SEC |
| Nov 13, 2023 | Paulson & Co. Inc. | 13GOld format | – | New | – | SEC |
| Oct 10, 2023 | Janus Henderson Group PLC | 13G/AOld format | – | – | – | SEC |
| Oct 5, 2023 | Baker Bros. Advisors LP | 13D/AOld format | – | – | – | SEC |
| Sep 8, 2023 | Janus Henderson Group PLC | 13GOld format | – | New | – | SEC |
| Aug 8, 2023 | Baker Bros. Advisors LP | 13D/AOld format | – | – | – | SEC |
| Jun 20, 2023 | Baker Bros. Advisors LP | 13DOld format | – | – | – | SEC |
| Feb 14, 2023 | Armistice Capital, LLC | 13G/AOld format | – | – | – | SEC |
| Feb 14, 2023 | Deep Track Capital, LP | 13G/AOld format | – | – | – | SEC |
| Feb 14, 2023 | Baker Bros. Advisors LP | 13G/AOld format | – | – | – | SEC |
| Feb 14, 2023 | Avoro Capital Advisors LLC | 13G/AOld format | – | – | – | SEC |
| Feb 9, 2023 | Vanguard Group Inc | 13G/AOld format | – | – | – | SEC |
| Feb 6, 2023 | Wellington Management Group LLP | 13G/AOld format | – | – | – | SEC |
| Feb 2, 2023 | State Street Corp | 13GOld format | – | New | – | SEC |
| Feb 1, 20234:54 PM ET | BlackRock Inc. | 13G/AOld format | – | – | – | SEC |
| May 19, 2022 | Deep Track Capital, LP | 13GOld format | – | New | – | SEC |
| Feb 15, 2022 | Armistice Capital, LLC | 13GOld format | – | New | – | SEC |
| Feb 14, 2022 | HealthCor Management, L.P. | 13G/AOld format | – | – | – | SEC |
| Feb 11, 2022 | Avoro Capital Advisors LLC | 13G/AOld format | – | – | – | SEC |
| Feb 10, 2022 | Vanguard Group Inc | 13G/AOld format | – | – | – | SEC |
| Feb 4, 2022 | Wellington Management Group LLP | 13G/AOld format | – | – | – | SEC |
| Feb 2, 20227:18 PM ET | BlackRock Inc. | 13G/AOld format | – | – | – | SEC |
| Dec 7, 2021 | Bay City Capital LLC | 13D/AOld format | – | – | – | SEC |
| Jul 9, 2021 | Capital Research Global Investors | 13G/AOld format | – | – | – | SEC |
| Feb 16, 2021 | Capital Research Global Investors | 13G/AOld format | – | – | – | SEC |
Form 144: proposed insider sales
86 notices from officers, directors and other affiliates planning to sell Madrigal Pharmaceuticals, Inc. shares, newest first.
| Filed (ET) | Seller | Shares to sell | Market value | Planned sale | Broker | Filing |
|---|---|---|---|---|---|---|
| Nov 6, 20264:27 PM ET | Shannon KelleyOfficer | 1.08K | $430.9K | Nov 6, 202610b5-1 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Sep 28, 20264:19 PM ET | Paul FriedmanDirector | 50.0K | $25.8M | Sep 28, 202610b5-1 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Sep 11, 20264:33 PM ET | William SiboldDirector · Officer | 5.22K | $2.78M | Sep 11, 202610b5-1 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Sep 9, 20266:05 PM ET | William John SiboldOfficer and Director | 6.36K | $3.40M | Sep 9, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Aug 20, 20264:18 PM ET | Shannon KelleyOfficer | 664 | $337.0K | Aug 17, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Jul 20, 20269:11 PM ET | William SiboldOfficer and Director | 2.50K | $1.38M | Jul 20, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Jun 1, 20264:31 PM ET | David SoergelOfficer | 1.04K | $518.2K | Jun 1, 202610b5-1 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| May 22, 20264:34 PM ET | Richard LevyDirector | 5.68K | $2.92M | May 22, 202610b5-1 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| May 18, 20265:34 PM ET | David SoergelOfficer | 844 | $442.0K | May 18, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Mar 6, 20266:58 PM ET | Mardi DierOfficer | 646 | $283.8K | Mar 6, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Mar 6, 20266:45 PM ET | William SiboldOfficer and Director | 1.66K | $730.6K | Mar 6, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Mar 6, 20266:28 PM ET | Shannon KelleyOfficer | 360 | $158.2K | Mar 6, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Mar 6, 20266:12 PM ET | Carole HuntsmanOfficer | 419 | $184.1K | Mar 6, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Mar 6, 20266:06 PM ET | Rebecca TaubDirector | 491 | $215.7K | Mar 6, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Mar 6, 20264:31 PM ET | Mardi DierOfficer | 1.34K | $587.0K | Mar 6, 202610b5-1 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Mar 2, 20265:29 PM ET | Mardi DierOfficer | 1.18K | $511.1K | Mar 2, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Jan 26, 20265:35 PM ET | Carole HuntsmanOfficer | 340 | $163.4K | Jan 26, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Jan 26, 20265:11 PM ET | William SiboldOfficer and Director | 1.58K | $757.7K | Jan 26, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Jan 26, 20265:02 PM ET | Rebecca TaubDirector | 647 | $310.9K | Jan 26, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Jan 26, 20264:31 PM ET | Carole A HuntsmanOfficer | 570 | $273.9K | Jan 26, 202610b5-1 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Jan 20, 20265:54 PM ET | Shannon KelleyOfficer | 263 | $131.9K | Jan 20, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Jan 20, 20265:38 PM ET | Rebecca TaubDirector | 2.24K | $1.12M | Jan 20, 2026 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Jan 20, 20264:39 PM ET | Shannon KelleyOfficer | 429 | $215.2K | Jan 20, 202610b5-1 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Jan 9, 20264:30 PM ET | Rebecca A TaubDirector | 18.6K | $10.4M | Jan 9, 202610b5-1 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
| Dec 10, 20254:17 PM ET | Paul FriedmanDirector | 49.6K | $27.5M | Dec 10, 202510b5-1 | Morgan Stanley Smith Barney LLC Executive Financial Services | SEC |
Showing the latest 25. See the MDGL notices from the last 12 months