Madrigal Pharmaceuticals, Inc.
MDGL- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001157601
In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 3 sales; 414 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Madrigal Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 352
- +51 vs. Q2 2025
- Shares held
- 23.4M
- +16.4K (+0.1%) vs. Q2 2025
- Total value
- $10.7B
- +$3.65B (+51.6%) vs. Q2 2025
- New holders
- 87
- 107 more added
- Sold out
- 36
- 107 more reduced
4 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MDGL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 414 | $12.7B |
| Q1 2026 | 380 | $12.4B |
| Q4 2025 | 387 | $13.7B |
| Q3 2025 | 352 | $10.7B |
| Q2 2025 | 305 | $7.13B |
| Q1 2025 | 321 | $7.85B |
| Q4 2024 | 283 | $7.08B |
| Q3 2024 | 257 | $4.77B |
| Q2 2024 | 257 | $6.41B |
| Q1 2024 | 266 | $5.64B |
| Q4 2023 | 226 | $4.57B |
| Q3 2023 | 206 | $2.54B |
| Q2 2023 | 208 | $3.43B |
| Q1 2023 | 223 | $3.36B |
| Q4 2022 | 189 | $3.86B |
| Q3 2022 | 135 | $763.2M |
| Q2 2022 | 138 | $857.7M |
| Q1 2022 | 140 | $1.20B |
| Q4 2021 | 144 | $1.01B |
| Q3 2021 | 133 | $876.5M |
| Q2 2021 | 151 | $1.09B |
| Q1 2021 | 137 | $1.43B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Madrigal Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 2,141,701 | $982.3M | 7.10% | +165,683+8.4% | Added |
| RTW Investments, LP | 1,993,687 | $914.4M | 11.27% | 00.0% | Unchanged |
| Paulson & Co. Inc. | 1,907,523 | $874.9M | 29.46% | −182,000−8.7% | Reduced |
| Janus Henderson Group PLC | 1,842,690 | $845.3M | 0.39% | −349,063−15.9% | Reduced |
| Avoro Capital Advisors LLC | 1,833,000 | $840.7M | 10.88% | −42,000−2.2% | Reduced |
| Vanguard Group Inc | 1,812,054 | $831.1M | 0.01% | −65,227−3.5% | Reduced |
| BlackRock, Inc. | 1,559,712 | $715.4M | 0.01% | +120,988+8.4% | Added |
| State Street Corp | 658,097 | $301.8M | 0.01% | −32,618−4.7% | Reduced |
| Geode Capital Management, LLC | 446,233 | $204.7M | 0.01% | +31,841+7.7% | Added |
| William Blair Investment Management, LLC | 411,802 | $188.9M | 0.49% | +61,513+17.6% | Added |
| Wellington Management Group LLP | 404,455 | $185.5M | 0.03% | +397,076+5,381.2% | Added |
| FMR LLC | 401,136 | $184.0M | 0.01% | −44,203−9.9% | Reduced |
| Goldman Sachs Group Inc | 386,100 | $177.1M | 0.03% | +196,260+103.4% | Added |
| Price T Rowe Associates Inc | 352,520 | $161.7M | 0.02% | −155,944−30.7% | Reduced |
| Invesco Ltd. | 299,565 | $137.4M | 0.02% | +99,209+49.5% | Added |
| Polar Capital Holdings Plc | 265,154 | $121.6M | 0.59% | +39,744+17.6% | Added |
| Morgan Stanley | 249,647 | $114.5M | 0.01% | +1,685+0.7% | Added |
| Bank of America Corp | 244,292 | $112.0M | 0.01% | −32,929−11.9% | Reduced |
| Hood River Capital Management LLC | 242,808 | $111.4M | 1.31% | −1,930−0.8% | Reduced |
| UBS Group AG | 217,343 | $99.7M | 0.02% | −288,371−57.0% | Reduced |
| Charles Schwab Investment Management Inc | 213,652 | $98.0M | 0.02% | +60,567+39.6% | Added |
| Artisan Partners Limited Partnership | 206,254 | $94.6M | 0.14% | +4,683+2.3% | Added |
| Erste Asset Management GmbH | 201,100 | $89.1M | 0.86% | 00.0% | Unchanged |
| Pictet Asset Management Holding SA | 191,796 | $87.7M | 0.08% | −16,470−7.9% | Reduced |
| American Century Companies Inc | 165,615 | $76.0M | 0.04% | −2,169−1.3% | Reduced |
| Northern Trust Corp | 159,988 | $73.4M | 0.01% | +17,120+12.0% | Added |
| Rock Springs Capital Management LP | 137,746 | $63.2M | 3.69% | −2,550−1.8% | Reduced |
| Fiera Capital Corp | 127,800 | $58.6M | 0.19% | −2,822−2.2% | Reduced |
| ArrowMark Colorado Holdings LLC | 123,259 | $56.5M | 1.05% | −21,549−14.9% | Reduced |
| Renaissance Technologies LLC | 120,682 | $55.4M | 0.07% | +109,846+1,013.7% | Added |
| Alkeon Capital Management LLC | 120,000 | $55.0M | 0.25% | +120,000 | New |
| Armistice Capital, LLC | 119,982 | $55.0M | 1.73% | −4,018−3.2% | Reduced |
| Driehaus Capital Management LLC | 115,974 | $53.2M | 0.38% | +115,974 | New |
| Affinity Asset Advisors, LLC | 115,000 | $52.7M | 4.91% | +35,000+43.8% | Added |
| Susquehanna International Group, LLP | 104,818 | $48.1M | 0.07% | +4,496+4.5% | Added |
| Woodline Partners LP | 103,847 | $47.6M | 0.22% | −55,776−34.9% | Reduced |
| Lord, Abbett & Co. LLC | 102,143 | $46.8M | 0.14% | +17,926+21.3% | Added |
| MPM Oncology Impact Management LP | 100,415 | $46.1M | 7.54% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 97,779 | $44.8M | 0.01% | +8,836+9.9% | Added |
| D. E. Shaw & Co., Inc. | 96,182 | $44.1M | 0.04% | −15,799−14.1% | Reduced |
| Jane Street Group, LLC | 95,734 | $43.9M | 0.05% | +95,734 | New |
| Adage Capital Partners GP, L.L.C. | 88,500 | $40.6M | 0.06% | −287,663−76.5% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 85,773 | $39.3M | 0.12% | −14,322−14.3% | Reduced |
| Balyasny Asset Management LLC | 82,401 | $37.8M | 0.08% | +47,901+138.8% | Added |
| Franklin Resources Inc | 75,570 | $34.7M | 0.01% | +14,855+24.5% | Added |
| EcoR1 Capital, LLC | 75,000 | $34.4M | 1.65% | 00.0% | Unchanged |
| Nuveen, LLC | 73,715 | $33.8M | 0.01% | +32,182+77.5% | Added |
| BNP Paribas Arbitrage, SA | 70,757 | $32.5M | 0.03% | +1,720+2.5% | Added |
| Raymond James Financial Inc | 70,584 | $32.4M | 0.01% | +15,651+28.5% | Added |
| New York State Common Retirement Fund | 69,273 | $31.8M | 0.04% | +8,211+13.4% | Added |
| Soleus Capital Management, L.P. | 68,336 | $31.3M | 1.68% | +60,336+754.2% | Added |
| Tri Locum Partners LP | 67,706 | $31.1M | 7.14% | −30,059−30.7% | Reduced |
| Voya Investment Management LLC | 59,437 | $27.3M | 0.03% | +8,347+16.3% | Added |
| Iron Triangle Partners LP | 58,378 | $26.8M | 3.81% | +58,378 | New |
| Ensign Peak Advisors, Inc | 53,267 | $24.4M | 0.04% | +4,868+10.1% | Added |
| EULAV Asset Management | 51,000 | $23.4M | 0.54% | +20,000+64.5% | Added |
| Emerald Advisers, LLC | 50,737 | $23.3M | 0.75% | −2,371−4.5% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 50,578 | $23.2M | 0.07% | −19,981−28.3% | Reduced |
| Candriam Luxembourg S.C.A. | 49,965 | $22.9M | 0.12% | 00.0% | Unchanged |
| Barclays PLC | 49,912 | $22.9M | 0.01% | −12,762−20.4% | Reduced |
| Citadel Advisors LLC | 48,372 | $22.2M | 0.02% | −158,967−76.7% | Reduced |
| JPMorgan Chase & Co | 47,824 | $21.9M | 0.00% | −8,030−14.4% | Reduced |
| Russell Investments Group, Ltd. | 44,885 | $20.6M | 0.02% | +10,870+32.0% | Added |
| Rheos Capital Works Inc. | 43,215 | $19.8M | 1.11% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 41,233 | $18.9M | 0.04% | −69,644−62.8% | Reduced |
| Tao Capital Management LP | 41,000 | $18.8M | 14.22% | −71,785−63.6% | Reduced |
| Wells Fargo & Company | 37,818 | $17.3M | 0.00% | +1,149+3.1% | Added |
| Deutsche Bank AG | 37,342 | $17.1M | 0.01% | +13,227+54.8% | Added |
| Alliancebernstein L.P. | 35,695 | $16.4M | 0.01% | +14,445+68.0% | Added |
| Emerald Mutual Fund Advisers Trust | 35,091 | $16.1M | 0.83% | −1,829−5.0% | Reduced |
| Ally Bridge Group (NY) LLC | 32,662 | $15.0M | 12.54% | +32,662 | New |
| Gilder Gagnon Howe & Co LLC | 30,848 | $14.1M | 0.14% | −705−2.2% | Reduced |
| Squarepoint Ops LLC | 29,936 | $13.7M | 0.03% | +25,554+583.2% | Added |
| Steadfast Capital Management LP | 29,800 | $13.7M | 0.25% | +29,800 | New |
| Swiss National Bank | 27,900 | $12.8M | 0.01% | +500+1.8% | Added |
| Bridgewater Associates, LP | 27,785 | $12.7M | 0.05% | +27,785 | New |
| Groupama Asset Managment | 27,444 | $12.6M | 0.18% | −13,447−32.9% | Reduced |
| Rhumbline Advisers | 27,263 | $12.5M | 0.01% | +900+3.4% | Added |
| California Public Employees Retirement System | 24,097 | $11.1M | 0.01% | −3,486−12.6% | Reduced |
| UBS Asset Management Americas Inc | 23,476 | $10.8M | 0.00% | −16,333−41.0% | Reduced |
| LPL Financial LLC | 22,538 | $10.3M | 0.00% | +8,417+59.6% | Added |
| Segall Bryant & Hamill, LLC | 22,490 | $10.3M | 0.14% | +22,490 | New |
| Legal & General Group Plc | 21,671 | $9.94M | 0.00% | −1,438−6.2% | Reduced |
| Man Group plc | 21,328 | $9.78M | 0.02% | +19,961+1,460.2% | Added |
| Jump Financial, LLC | 20,956 | $9.61M | 0.12% | +20,956 | New |
| Royal Bank of Canada | 20,173 | $9.25M | 0.00% | +10,570+110.1% | Added |
| SEI Investments Co | 19,115 | $8.77M | 0.01% | +1,573+9.0% | Added |
| Rafferty Asset Management, LLC | 18,715 | $8.58M | 0.03% | −5,818−23.7% | Reduced |
| Neuberger Berman Group LLC | 18,531 | $8.50M | 0.01% | +18,531 | New |
| Rockefeller Capital Management L.P. | 18,451 | $8.46M | 0.02% | +503+2.8% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 18,363 | $8.44M | 0.03% | +14,385+361.6% | Added |
| Rhenman & Partners Asset Management AB | 18,250 | $8.37M | 0.93% | +18,250 | New |
| Cubist Systematic Strategies, LLC | 17,889 | $8.20M | 0.12% | +17,889 | New |
| WCM Investment Management, LLC | 18,291 | $8.10M | 0.02% | +18,291 | New |
| Manufacturers Life Insurance Company, The | 17,327 | $7.95M | 0.01% | −6,089−26.0% | Reduced |
| Schroder Investment Management Group | 16,612 | $7.36M | 0.01% | −16,595−50.0% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 15,288 | $7.01M | 0.01% | +12,157+388.3% | Added |
| AXA Investment Managers S.A. | 15,036 | $6.90M | 0.02% | +15,036 | New |
| Resolute Capital Asset Partners LLC | 15,000 | $6.88M | 3.60% | +15,000 | New |
| Envestnet Asset Management Inc | 14,566 | $6.68M | 0.00% | +64+0.4% | Added |