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Madrigal Pharmaceuticals, Inc.

MDGL
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001157601

In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 3 sales; 414 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Madrigal Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
189
+57 vs. Q3 2022
Shares held
13.3M
+1.60M (+13.6%) vs. Q3 2022
Total value
$3.86B
+$3.10B (+406.2%) vs. Q3 2022
New holders
80
54 more added
Sold out
23
39 more reduced

3 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MDGL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 189 institutions
Q1 2021: 137 institutionsQ2 2021: 151 institutionsQ3 2021: 133 institutionsQ4 2021: 144 institutionsQ1 2022: 140 institutionsQ2 2022: 138 institutionsQ3 2022: 135 institutionsQ4 2022: 189 institutionsQ1 2023: 223 institutionsQ2 2023: 208 institutionsQ3 2023: 206 institutionsQ4 2023: 226 institutionsQ1 2024: 266 institutionsQ2 2024: 257 institutionsQ3 2024: 257 institutionsQ4 2024: 283 institutionsQ1 2025: 321 institutionsQ2 2025: 305 institutionsQ3 2025: 352 institutionsQ4 2025: 387 institutionsQ1 2026: 380 institutionsQ2 2026: 414 institutions
Value heldQ4 2022: $3.86B
Q1 2021: $1.43BQ2 2021: $1.09BQ3 2021: $876.5MQ4 2021: $1.01BQ1 2022: $1.20BQ2 2022: $857.7MQ3 2022: $763.2MQ4 2022: $3.86BQ1 2023: $3.36BQ2 2023: $3.43BQ3 2023: $2.54BQ4 2023: $4.57BQ1 2024: $5.64BQ2 2024: $6.41BQ3 2024: $4.77BQ4 2024: $7.08BQ1 2025: $7.85BQ2 2025: $7.13BQ3 2025: $10.7BQ4 2025: $13.7BQ1 2026: $12.4BQ2 2026: $12.7B
Institutions holding MDGL and their total value by quarter
QuarterHoldersValue
Q2 2026414$12.7B
Q1 2026380$12.4B
Q4 2025387$13.7B
Q3 2025352$10.7B
Q2 2025305$7.13B
Q1 2025321$7.85B
Q4 2024283$7.08B
Q3 2024257$4.77B
Q2 2024257$6.41B
Q1 2024266$5.64B
Q4 2023226$4.57B
Q3 2023206$2.54B
Q2 2023208$3.43B
Q1 2023223$3.36B
Q4 2022189$3.86B
Q3 2022135$763.2M
Q2 2022138$857.7M
Q1 2022140$1.20B
Q4 2021144$1.01B
Q3 2021133$876.5M
Q2 2021151$1.09B
Q1 2021137$1.43B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Madrigal Pharmaceuticals, Inc.; share changes are against Q3 2022.

Institutions holding MDGL in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Avoro Capital Advisors LLC1,660,000$481.8M7.20%+125,000+8.1%Added
Baker Bros. Advisors LP1,545,113$448.5M2.69%+45,900+3.1%Added
Vanguard Group Inc1,266,375$367.6M0.01%+12,070+1.0%Added
State Street Corp1,260,993$366.0M0.02%+294,352+30.5%Added
BlackRock Inc.986,572$286.4M0.01%−12,932−1.3%Reduced
Perceptive Advisors LLC731,932$212.4M6.12%+400,909+121.1%Added
Avidity Partners Management LP430,000$124.8M2.92%+430,000New
Rock Springs Capital Management LP348,121$101.0M2.43%+30,636+9.6%Added
TCG Crossover Management, LLC288,054$83.6M14.76%+258,054+860.2%Added
Geode Capital Management, LLC236,585$68.7M0.01%+6,799+3.0%Added
Artisan Partners Limited Partnership212,290$61.6M0.11%+1,808+0.9%Added
Armistice Capital, LLC208,000$60.4M1.62%−1,028,000−83.2%Reduced
FMR LLC198,490$57.6M0.01%+34,716+21.2%Added
Janus Henderson Group PLC182,648$53.0M0.04%+96,265+111.4%Added
Lord, Abbett & Co. LLC178,518$51.8M0.19%+178,518New
Citadel Advisors LLC170,287$49.4M0.06%+128,143+304.1%Added
Goldman Sachs Group Inc163,791$47.5M0.01%−16,611−9.2%Reduced
Pictet Asset Management SA159,154$46.2M0.07%+86,153+118.0%Added
D. E. Shaw & Co., Inc.153,438$44.5M0.08%+130,458+567.7%Added
Farallon Capital Management, L.L.C.153,000$44.4M0.29%+153,000New
L1 Capital Pty Ltd133,312$38.7M5.97%−27,851−17.3%Reduced
Assenagon Asset Management S.A.124,443$36.1M0.15%+115,234+1,251.3%Added
Adage Capital Partners GP, L.L.C.124,391$36.1M0.09%+115,291+1,266.9%Added
Norges Bank116,300$33.8M0.01%00.0%Unchanged
Northern Trust Corp111,493$32.4M0.01%−1,912−1.7%Reduced
Morgan Stanley109,420$31.8M0.00%+50,356+85.3%Added
Rafferty Asset Management, LLC105,390$30.6M0.26%+39,469+59.9%Added
UBS Group AG96,690$28.1M0.01%+71,227+279.7%Added
Bank of America Corp92,799$26.9M0.00%+52,439+129.9%Added
Charles Schwab Investment Management Inc91,450$26.5M0.01%+1,971+2.2%Added
Barclays PLC87,868$25.5M0.02%+44,453+102.4%Added
Tao Capital Management LP77,657$22.5M16.95%00.0%Unchanged
Affinity Asset Advisors, LLC70,000$20.3M9.31%−30,000−30.0%Reduced
Deutsche Bank AG61,867$18.0M0.01%+10,417+20.2%Added
Connor, Clark & Lunn Investment Management Ltd.60,407$17.5M0.10%+35,418+141.7%Added
Logos Global Management LP60,000$17.4M2.04%+60,000New
Jennison Associates LLC58,956$17.1M0.02%−54,544−48.1%Reduced
Price T Rowe Associates Inc55,250$16.0M0.00%+8,629+18.5%Added
JPMorgan Chase & Co54,426$15.8M0.00%+18,094+49.8%Added
Silverarc Capital Management, LLC49,898$14.5M4.99%+49,898New
BNP Paribas Arbitrage, SA46,804$13.6M0.03%+25,200+116.6%Added
Citigroup Inc46,549$13.5M0.02%−13,698−22.7%Reduced
Hennion & Walsh Asset Management, Inc.45,943$13.3M0.82%−5,064−9.9%Reduced
Jane Street Group, LLC44,080$12.8M0.02%+44,080New
Bank of New York Mellon Corp42,971$12.5M0.00%+2,269+5.6%Added
Invesco Ltd.32,984$9.57M0.00%+27,014+452.5%Added
Wellington Management Group LLP31,830$9.24M0.00%+7,654+31.7%Added
Swiss National Bank28,900$8.39M0.01%+700+2.5%Added
Macquarie Group Ltd28,500$8.27M0.01%−849−2.9%Reduced
MPM Oncology Impact Management LP26,773$7.77M2.02%−17,974−40.2%Reduced
Tri Locum Partners LP26,386$7.66M3.39%+26,386New
Wells Fargo & Company25,528$7.41M0.00%−425−1.6%Reduced
Alliancebernstein L.P.24,968$7.25M0.00%+8,268+49.5%Added
New York State Common Retirement Fund21,613$6.27M0.01%+4,024+22.9%Added
Ghost Tree Capital, LLC20,000$5.80M2.48%−5,000−20.0%Reduced
Rhumbline Advisers17,319$5.03M0.01%+940+5.7%Added
Fred Alger Management, LLC16,120$4.68M0.03%+16,120New
Mutual of America Capital Management LLC15,954$4.63M0.06%+215+1.4%Added
California State Teachers Retirement System15,526$4.51M0.01%+197+1.3%Added
Lisanti Capital Growth, LLC14,725$4.27M0.58%+14,725New
Schonfeld Strategic Advisors LLC14,600$4.24M0.04%−54,136−78.8%Reduced
Journey Strategic Wealth LLC13,861$4.02M0.47%+36+0.3%Added
Royal Bank of Canada13,150$3.82M0.00%+2,570+24.3%Added
Prudential Financial Inc13,094$3.80M0.01%−7,755−37.2%Reduced
Dimensional Fund Advisors LP13,079$3.80M0.00%−32,916−71.6%Reduced
Emerald Advisers, LLC12,988$3.77M0.18%+12,988New
Voya Investment Management LLC12,670$3.68M0.00%+2,835+28.8%Added
Cambridge Investment Research Advisors, Inc.12,560$3.65M0.02%+4,710+60.0%Added
Cubist Systematic Strategies, LLC11,901$3.45M0.03%+1,238+11.6%Added
Legal & General Group Plc11,775$3.42M0.00%+100+0.9%Added
State of Wisconsin Investment Board11,492$3.34M0.01%−739−6.0%Reduced
Erste Asset Management GmbH11,000$3.26M0.07%+11,000New
Trexquant Investment LP11,190$3.25M0.09%+11,190New
Susquehanna International Group, LLP11,064$3.21M0.01%−11,073−50.0%Reduced
HRT Financial LP10,919$3.17M0.04%+10,919New
Emerald Mutual Fund Advisers Trust10,469$3.04M0.19%+10,469New
Credit Suisse AG10,006$2.90M0.00%−62−0.6%Reduced
Two Sigma Investments, LP9,440$2.74M0.01%+9,440New
Algert Global LLC8,650$2.51M0.14%−590−6.4%Reduced
Tudor Investment Corp Et Al8,445$2.45M0.06%+617+7.9%Added
Nuveen Asset Management, LLC36,770$2.35M0.00%+1,549+4.4%Added
Knott David M Jr8,000$2.32M1.00%+7,000+700.0%Added
Parkman Healthcare Partners LLC7,341$2.13M0.57%−14,249−66.0%Reduced
EAM Investors, LLC7,198$2.09M0.43%+7,198New
MetLife Investment Management6,682$1.94M0.01%00.0%Unchanged
Caption Management, LLC6,518$1.89M0.32%+6,518New
American International Group, Inc.6,022$1.75M0.01%−22−0.4%Reduced
DekaBank Deutsche Girozentrale5,800$1.71M0.00%+5,800New
Wintrust Investments LLC5,750$1.67M0.22%+5,750New
AtonRa Partners5,706$1.66M2.11%−1,543−21.3%Reduced
EAM Global Investors LLC5,636$1.64M0.42%+5,636New
E Fund Management Co., Ltd.5,532$1.61M0.13%+994+21.9%Added
SEI Investments Co5,264$1.53M0.00%+5,264New
Manufacturers Life Insurance Company, The4,986$1.45M0.00%−106−2.1%Reduced
Voloridge Investment Management, LLC4,957$1.44M0.01%+4,957New
FORA Capital, LLC4,851$1.41M0.23%+4,851New
Jump Financial, LLC4,588$1.33M0.07%+4,588New
Renaissance Technologies LLC4,582$1.33M0.00%+4,582New
State Board of Administration of Florida Retirement System4,557$1.32M0.00%−1,120−19.7%Reduced
Principal Financial Group Inc4,197$1.22M0.00%+366+9.6%Added