Madrigal Pharmaceuticals, Inc.
MDGL- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001157601
In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 3 sales; 414 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Madrigal Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 387
- +44 vs. Q3 2025
- Shares held
- 23.6M
- +230.2K (+1.0%) vs. Q3 2025
- Total value
- $13.7B
- +$3.02B (+28.2%) vs. Q3 2025
- New holders
- 85
- 137 more added
- Sold out
- 41
- 113 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MDGL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 414 | $12.7B |
| Q1 2026 | 380 | $12.4B |
| Q4 2025 | 387 | $13.7B |
| Q3 2025 | 352 | $10.7B |
| Q2 2025 | 305 | $7.13B |
| Q1 2025 | 321 | $7.85B |
| Q4 2024 | 283 | $7.08B |
| Q3 2024 | 257 | $4.77B |
| Q2 2024 | 257 | $6.41B |
| Q1 2024 | 266 | $5.64B |
| Q4 2023 | 226 | $4.57B |
| Q3 2023 | 206 | $2.54B |
| Q2 2023 | 208 | $3.43B |
| Q1 2023 | 223 | $3.36B |
| Q4 2022 | 189 | $3.86B |
| Q3 2022 | 135 | $763.2M |
| Q2 2022 | 138 | $857.7M |
| Q1 2022 | 140 | $1.20B |
| Q4 2021 | 144 | $1.01B |
| Q3 2021 | 133 | $876.5M |
| Q2 2021 | 151 | $1.09B |
| Q1 2021 | 137 | $1.43B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Madrigal Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 2,141,701 | $1.25B | 7.30% | 00.0% | Unchanged |
| RTW Investments, LP | 1,993,687 | $1.16B | 11.63% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,808,894 | $1.05B | 0.02% | −3,160−0.2% | Reduced |
| Avoro Capital Advisors LLC | 1,807,500 | $1.05B | 10.35% | −25,500−1.4% | Reduced |
| Paulson & Co. Inc. | 1,707,522 | $994.4M | 30.48% | −200,001−10.5% | Reduced |
| BlackRock, Inc. | 1,644,750 | $957.8M | 0.02% | +85,038+5.5% | Added |
| Janus Henderson Group PLC | 1,584,843 | $918.2M | 0.41% | −257,847−14.0% | Reduced |
| State Street Corp | 583,003 | $339.5M | 0.01% | −75,094−11.4% | Reduced |
| Wellington Management Group LLP | 461,402 | $268.7M | 0.05% | +56,947+14.1% | Added |
| Geode Capital Management, LLC | 451,743 | $263.1M | 0.02% | +5,510+1.2% | Added |
| FMR LLC | 439,398 | $255.9M | 0.01% | +38,262+9.5% | Added |
| Bank of America Corp | 416,025 | $242.3M | 0.02% | +171,733+70.3% | Added |
| Invesco Ltd. | 365,314 | $212.7M | 0.02% | +65,749+21.9% | Added |
| William Blair Investment Management, LLC | 354,220 | $206.3M | 0.58% | −57,582−14.0% | Reduced |
| Price T Rowe Associates Inc | 313,659 | $182.7M | 0.02% | −38,861−11.0% | Reduced |
| Goldman Sachs Group Inc | 305,847 | $178.1M | 0.03% | −80,253−20.8% | Reduced |
| Polar Capital Holdings Plc | 270,151 | $157.3M | 0.72% | +4,997+1.9% | Added |
| Armistice Capital, LLC | 265,705 | $154.7M | 3.79% | +145,723+121.5% | Added |
| Hood River Capital Management LLC | 247,560 | $144.2M | 1.58% | +4,752+2.0% | Added |
| Lord, Abbett & Co. LLC | 244,796 | $142.6M | 0.44% | +142,653+139.7% | Added |
| Alkeon Capital Management LLC | 240,000 | $139.8M | 0.61% | +120,000+100.0% | Added |
| Charles Schwab Investment Management Inc | 219,099 | $127.6M | 0.02% | +5,447+2.5% | Added |
| Artisan Partners Limited Partnership | 198,693 | $115.7M | 0.18% | −7,561−3.7% | Reduced |
| Norges Bank | 196,393 | $114.4M | 0.01% | +196,393 | New |
| Deutsche Bank AG | 192,109 | $111.9M | 0.04% | +154,767+414.5% | Added |
| American Century Companies Inc | 185,116 | $107.8M | 0.05% | +19,501+11.8% | Added |
| Pictet Asset Management Holding SA | 181,949 | $106.0M | 0.10% | −9,847−5.1% | Reduced |
| Fiera Capital Corp | 169,456 | $98.7M | 0.31% | +41,656+32.6% | Added |
| Northern Trust Corp | 151,802 | $88.4M | 0.01% | −8,186−5.1% | Reduced |
| Morgan Stanley | 150,462 | $87.6M | 0.01% | −99,185−39.7% | Reduced |
| Erste Asset Management GmbH | 141,100 | $82.3M | 0.69% | −60,000−29.8% | Reduced |
| Rock Springs Capital Management LP | 139,618 | $81.3M | 4.17% | +1,872+1.4% | Added |
| Bank of New York Mellon Corp | 136,869 | $79.7M | 0.01% | +39,090+40.0% | Added |
| Point72 Asset Management, L.P. | 126,435 | $73.6M | 0.12% | +85,202+206.6% | Added |
| Woodline Partners LP | 125,659 | $73.2M | 0.28% | +21,812+21.0% | Added |
| Nuveen, LLC | 118,363 | $68.9M | 0.02% | +44,648+60.6% | Added |
| Driehaus Capital Management LLC | 111,666 | $65.0M | 0.44% | −4,308−3.7% | Reduced |
| UBS Group AG | 102,641 | $59.8M | 0.01% | −114,702−52.8% | Reduced |
| MPM Oncology Impact Management LP | 96,780 | $56.4M | 6.45% | −3,635−3.6% | Reduced |
| Jane Street Group, LLC | 93,114 | $54.2M | 0.06% | −2,620−2.7% | Reduced |
| D. E. Shaw & Co., Inc. | 88,554 | $51.6M | 0.04% | −7,628−7.9% | Reduced |
| Franklin Resources Inc | 86,076 | $50.1M | 0.01% | +10,506+13.9% | Added |
| Tri Locum Partners LP | 86,023 | $50.1M | 6.50% | +18,317+27.1% | Added |
| Renaissance Technologies LLC | 83,862 | $48.8M | 0.08% | −36,820−30.5% | Reduced |
| ArrowMark Colorado Holdings LLC | 82,624 | $48.1M | 1.06% | −40,635−33.0% | Reduced |
| New York State Common Retirement Fund | 75,933 | $44.2M | 0.06% | +6,660+9.6% | Added |
| Squarepoint Ops LLC | 74,934 | $43.6M | 0.09% | +44,998+150.3% | Added |
| BNP Paribas Arbitrage, SA | 73,707 | $42.9M | 0.03% | +2,950+4.2% | Added |
| First Light Asset Management, LLC | 66,831 | $38.9M | 2.98% | +55,292+479.2% | Added |
| Raymond James Financial Inc | 66,724 | $38.9M | 0.01% | −3,860−5.5% | Reduced |
| Susquehanna International Group, LLP | 64,466 | $37.5M | 0.05% | −40,352−38.5% | Reduced |
| Voya Investment Management LLC | 64,254 | $37.4M | 0.04% | +4,817+8.1% | Added |
| Candriam Luxembourg S.C.A. | 63,906 | $37.2M | 0.19% | +13,941+27.9% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 58,295 | $33.9M | 0.09% | −27,478−32.0% | Reduced |
| Jain Global LLC | 52,721 | $30.7M | 0.30% | +52,721 | New |
| Ensign Peak Advisors, Inc | 51,010 | $29.7M | 0.05% | −2,257−4.2% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 50,631 | $29.5M | 0.08% | +53+0.1% | Added |
| EULAV Asset Management | 49,000 | $28.5M | 0.76% | −2,000−3.9% | Reduced |
| Russell Investments Group, Ltd. | 48,159 | $28.0M | 0.03% | +3,274+7.3% | Added |
| Canada Pension Plan Investment Board | 46,120 | $26.9M | 0.02% | +37,120+412.4% | Added |
| Wells Fargo & Company | 43,457 | $25.3M | 0.00% | +5,639+14.9% | Added |
| JPMorgan Chase & Co | 40,079 | $23.3M | 0.00% | −7,745−16.2% | Reduced |
| Marshall Wace, LLP | 39,578 | $23.0M | 0.02% | +38,878+5,554.0% | Added |
| Emerald Advisers, LLC | 38,913 | $22.7M | 0.70% | −11,824−23.3% | Reduced |
| Barclays PLC | 38,720 | $22.5M | 0.01% | −11,192−22.4% | Reduced |
| Citadel Advisors LLC | 36,134 | $21.0M | 0.01% | −12,238−25.3% | Reduced |
| Atika Capital Management LLC | 34,000 | $19.8M | 2.76% | +34,000 | New |
| Segall Bryant & Hamill, LLC | 33,520 | $19.5M | 0.26% | +11,030+49.0% | Added |
| Gilder Gagnon Howe & Co LLC | 33,468 | $19.5M | 0.21% | +2,620+8.5% | Added |
| Public Sector Pension Investment Board | 32,871 | $19.1M | 0.06% | +32,871 | New |
| California Public Employees Retirement System | 31,286 | $18.2M | 0.01% | +7,189+29.8% | Added |
| Affinity Asset Advisors, LLC | 31,131 | $18.1M | 1.30% | −83,869−72.9% | Reduced |
| Groupama Asset Managment | 30,620 | $17.8M | 0.26% | +3,176+11.6% | Added |
| Ameriprise Financial Inc | 29,287 | $17.1M | 0.00% | +16,290+125.3% | Added |
| Schroder Investment Management Group | 29,051 | $17.0M | 0.01% | +12,439+74.9% | Added |
| Swiss National Bank | 28,580 | $16.6M | 0.01% | +680+2.4% | Added |
| Steadfast Capital Management LP | 26,850 | $15.6M | 0.27% | −2,950−9.9% | Reduced |
| Rheos Capital Works Inc. | 26,215 | $15.3M | 0.98% | −17,000−39.3% | Reduced |
| Emerald Mutual Fund Advisers Trust | 24,996 | $14.6M | 0.71% | −10,095−28.8% | Reduced |
| First Trust Advisors LP | 24,819 | $14.5M | 0.01% | +21,024+554.0% | Added |
| UBS Asset Management Americas Inc | 23,846 | $13.9M | 0.00% | +370+1.6% | Added |
| Rhumbline Advisers | 23,691 | $13.8M | 0.01% | −3,572−13.1% | Reduced |
| Citigroup Inc | 23,327 | $13.6M | 0.01% | +13,679+141.8% | Added |
| Adage Capital Partners GP, L.L.C. | 23,226 | $13.5M | 0.02% | −65,274−73.8% | Reduced |
| SEI Investments Co | 23,076 | $13.4M | 0.01% | +3,961+20.7% | Added |
| Alliancebernstein L.P. | 21,912 | $12.8M | 0.00% | −13,783−38.6% | Reduced |
| Tao Capital Management LP | 21,000 | $12.2M | 10.53% | −20,000−48.8% | Reduced |
| Rockefeller Capital Management L.P. | 19,661 | $11.4M | 0.02% | +1,210+6.6% | Added |
| Rhenman & Partners Asset Management AB | 19,550 | $11.4M | 1.06% | +1,300+7.1% | Added |
| Dimensional Fund Advisors LP | 19,321 | $11.3M | 0.00% | +13,522+233.2% | Added |
| Jump Financial, LLC | 19,221 | $11.2M | 0.14% | −1,735−8.3% | Reduced |
| Bridgewater Associates, LP | 19,218 | $11.2M | 0.04% | −8,567−30.8% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 19,076 | $11.1M | 0.02% | +3,788+24.8% | Added |
| Neuberger Berman Group LLC | 18,660 | $10.9M | 0.01% | +129+0.7% | Added |
| StemPoint Capital LP | 17,736 | $10.3M | 1.77% | +9,529+116.1% | Added |
| WCM Investment Management, LLC | 17,254 | $10.1M | 0.02% | −1,037−5.7% | Reduced |
| LPL Financial LLC | 16,542 | $9.63M | 0.00% | −5,996−26.6% | Reduced |
| Federated Hermes, Inc. | 16,325 | $9.51M | 0.02% | +12,440+320.2% | Added |
| Manufacturers Life Insurance Company, The | 16,052 | $9.36M | 0.01% | −1,275−7.4% | Reduced |
| Envestnet Asset Management Inc | 15,372 | $8.95M | 0.00% | +806+5.5% | Added |