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Madrigal Pharmaceuticals, Inc.

MDGL
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001157601

In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 3 sales; 414 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Madrigal Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
387
+44 vs. Q3 2025
Shares held
23.6M
+230.2K (+1.0%) vs. Q3 2025
Total value
$13.7B
+$3.02B (+28.2%) vs. Q3 2025
New holders
85
137 more added
Sold out
41
113 more reduced

9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MDGL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 387 institutions
Q1 2021: 137 institutionsQ2 2021: 151 institutionsQ3 2021: 133 institutionsQ4 2021: 144 institutionsQ1 2022: 140 institutionsQ2 2022: 138 institutionsQ3 2022: 135 institutionsQ4 2022: 189 institutionsQ1 2023: 223 institutionsQ2 2023: 208 institutionsQ3 2023: 206 institutionsQ4 2023: 226 institutionsQ1 2024: 266 institutionsQ2 2024: 257 institutionsQ3 2024: 257 institutionsQ4 2024: 283 institutionsQ1 2025: 321 institutionsQ2 2025: 305 institutionsQ3 2025: 352 institutionsQ4 2025: 387 institutionsQ1 2026: 380 institutionsQ2 2026: 414 institutions
Value heldQ4 2025: $13.7B
Q1 2021: $1.43BQ2 2021: $1.09BQ3 2021: $876.5MQ4 2021: $1.01BQ1 2022: $1.20BQ2 2022: $857.7MQ3 2022: $763.2MQ4 2022: $3.86BQ1 2023: $3.36BQ2 2023: $3.43BQ3 2023: $2.54BQ4 2023: $4.57BQ1 2024: $5.64BQ2 2024: $6.41BQ3 2024: $4.77BQ4 2024: $7.08BQ1 2025: $7.85BQ2 2025: $7.13BQ3 2025: $10.7BQ4 2025: $13.7BQ1 2026: $12.4BQ2 2026: $12.7B
Institutions holding MDGL and their total value by quarter
QuarterHoldersValue
Q2 2026414$12.7B
Q1 2026380$12.4B
Q4 2025387$13.7B
Q3 2025352$10.7B
Q2 2025305$7.13B
Q1 2025321$7.85B
Q4 2024283$7.08B
Q3 2024257$4.77B
Q2 2024257$6.41B
Q1 2024266$5.64B
Q4 2023226$4.57B
Q3 2023206$2.54B
Q2 2023208$3.43B
Q1 2023223$3.36B
Q4 2022189$3.86B
Q3 2022135$763.2M
Q2 2022138$857.7M
Q1 2022140$1.20B
Q4 2021144$1.01B
Q3 2021133$876.5M
Q2 2021151$1.09B
Q1 2021137$1.43B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Madrigal Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding MDGL in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Avion Wealth1$00.00%+1New
TD Capital Management LLC1$5820.00%00.0%Unchanged
Bogart Wealth, LLC1$5820.00%00.0%Unchanged
Fortitude Family Office, LLC1$5820.00%00.0%Unchanged
Marquette Asset Management, LLC1$5830.00%−2−66.7%Reduced
SJS Investment Consulting Inc.1$5830.00%+1New
Rachor Investment Advisory Services, LLC1$5830.00%+1New
CX Institutional2$1.00K0.00%+2New
South State Corp.2$1.17K0.00%00.0%Unchanged
Caitlin John, LLC2$1.17K0.00%00.0%Unchanged
Hughes Financial Services, LLC2$1.17K0.00%+2New
UMA Financial Services, Inc.3$1.75K0.00%+2+200.0%Added
Park Place Capital Corp4$2.33K0.00%00.0%Unchanged
Cary Street Partner Investment Advisory LLC4$2.33K0.00%+4New
Cornerstone Financial Management LLC4$2.33K0.00%+4New
Retirement Wealth Solutions LLC4$2.33K0.00%00.0%Unchanged
Atlantic Union Bankshares Corp4$2.33K0.00%+4New
EverSource Wealth Advisors, LLC5$2.91K0.00%+1+25.0%Added
Brown Brothers Harriman & Co5$2.91K0.00%00.0%Unchanged
Zions Bancorporation, National Association5$2.91K0.00%+5New
Webster Bank, N. A.6$3.49K0.00%00.0%Unchanged
Meeder Asset Management Inc7$4.08K0.00%00.0%Unchanged
Signature Resources Capital Management, LLC7$4.08K0.00%00.0%Unchanged
Bell Investment Advisors, Inc8$4.66K0.00%+3+60.0%Added
Whittier Trust Co of Nevada Inc9$5.02K0.00%00.0%Unchanged
Cape Investment Advisory, Inc.9$5.24K0.00%00.0%Unchanged
Massmutual Trust Co FSB10$5.82K0.00%00.0%Unchanged
Keating Financial Advisory Services, Inc.10$5.82K0.00%+10New
Parkside Financial Bank & Trust10$5.82K0.00%00.0%Unchanged
Motiv8 Investments LLC10$6.00K0.00%+10New
Aster Capital Management (DIFC) Ltd11$6.41K0.00%−74−87.1%Reduced
Vermillion & White Wealth Management Group, LLC14$8.15K0.00%00.0%Unchanged
Harbor Investment Advisory, LLC14$8.15K0.00%+14New
Larson Financial Group LLC17$9.90K0.00%+2+13.3%Added
Steward Partners Investment Advisory, LLC21$12.2K0.00%+9+75.0%Added
Sound Income Strategies, LLC25$12.5K0.00%+25New
MV Capital Management, Inc.22$12.8K0.00%00.0%Unchanged
Contravisory Investment Management, Inc.23$13.4K0.00%+23New
Compagnie Lombard Odier SCmA24$14.0K0.00%−80−76.9%Reduced
Rothschild Investment LLC24$14.0K0.00%00.0%Unchanged
Bessemer Group Inc24$14.0K0.00%+19+380.0%Added
Bradley & Co. Private Wealth Management, LLC27$15.7K0.01%00.0%Unchanged
SRS Capital Advisors, Inc.27$15.7K0.00%+12+80.0%Added
Leonteq Securities AG29$16.9K0.00%−27−48.2%Reduced
Huntington National Bank29$16.9K0.00%−1−3.3%Reduced
Rakuten Securities, Inc.30$17.5K0.01%00.0%Unchanged
Quattro Advisors LLC31$18.1K0.01%+31New
City Holding Co40$23.3K0.00%+40New
Basecamp Wealth Advisors LLC43$25.0K0.01%+43New
NBC Securities, Inc.48$28.0K0.00%00.0%Unchanged
Flagship Harbor Advisors, LLC50$29.1K0.00%+50New
McIlrath & Eck, LLC52$30.3K0.00%00.0%Unchanged
CIBC Private Wealth Group, LLC52$30.3K0.00%+1+2.0%Added
Quarry LP55$32.0K0.01%−31−36.0%Reduced
SBI Securities Co., Ltd.61$35.5K0.00%−12−16.4%Reduced
Aventura Private Wealth, LLC62$36.1K0.01%00.0%Unchanged
MAI Capital Management67$39.0K0.00%+61+1,016.7%Added
Kemnay Advisory Services Inc.67$39.0K0.01%+67New
Optiver Holding B.V.68$39.6K0.00%−68−50.0%Reduced
First Horizon Corp68$39.6K0.00%−7−9.3%Reduced
Daiwa Securities Group Inc.68$40.0K0.00%−2−2.9%Reduced
Walleye Capital LLC69$40.2K0.00%+69New
PEAK6 LLC77$44.9K0.00%+77New
Global Retirement Partners, LLC82$47.8K0.00%+8+10.8%Added
CoreCap Advisors, LLC82$47.8K0.00%+14+20.6%Added
Eastern Bank86$50.1K0.00%+21+32.3%Added
Accent Capital Management, LLC94$54.7K0.02%+37+64.9%Added
SageView Advisory Group, LLC112$65.2K0.00%+112New
Signaturefd, LLC115$67.0K0.00%00.0%Unchanged
Sterling Capital Management LLC122$71.0K0.00%+77+171.1%Added
GAMMA Investing LLC138$80.4K0.00%+48+53.3%Added
Farther Finance Advisors, LLC140$81.5K0.00%+36+34.6%Added
Torren Management, LLC155$90.3K0.05%+155New
Valley National Advisers Inc161$93.0K0.01%+122+312.8%Added
Smartleaf Asset Management LLC187$109.2K0.00%+63+50.8%Added
Montag A & Associates Inc194$113.0K0.01%00.0%Unchanged
Jones Financial Companies LLLP199$115.9K0.00%00.0%Unchanged
Danske Bank A/S200$116.5K0.00%+200New
Walleye Trading LLC214$124.6K0.00%+214New
Umb Bank N A230$133.9K0.00%00.0%Unchanged
Pinnacle Wealth Planning Services, Inc.233$135.7K0.01%+233New
Parallel Advisors, LLC251$146.2K0.00%−8−3.1%Reduced
The PNC Financial Services Group, Inc.277$161.3K0.00%+15+5.7%Added
Covestor Ltd309$180.0K0.09%+268+653.7%Added
Destination Wealth Management350$203.8K0.01%+350New
Sectoral Asset Management Inc352$205.0K0.16%−378−51.8%Reduced
Virtus ETF Advisers LLC360$209.6K0.10%+360New
Quantinno Capital Management LP364$212.0K0.00%+364New
Callan Family Office, LLC366$213.1K0.00%+366New
Arrowpoint Investment Partners (Singapore) Pte. Ltd.371$216.0K0.03%−421−53.2%Reduced
Kozak & Associates, Inc.424$218.0K0.04%00.0%Unchanged
RSM US Wealth Management LLC381$222.4K0.00%+381New
Oppenheimer & Co Inc392$228.3K0.00%+392New
Bridgefront Capital, LLC393$228.9K0.06%−323−45.1%Reduced
KBC Group NV414$241.0K0.00%00.0%Unchanged
Quest Partners LLC420$244.6K0.01%+368+707.7%Added
Washington Trust Co420$244.6K0.01%+420New
Ethic Inc.426$248.1K0.00%+426New
Nisa Investment Advisors, LLC429$249.8K0.00%−6−1.4%Reduced
Loring Wolcott & Coolidge Fiduciary Advisors LLP500$250.2K0.00%00.0%Unchanged