Madrigal Pharmaceuticals, Inc.
MDGL- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001157601
In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 3 sales; 414 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Madrigal Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 387
- +44 vs. Q3 2025
- Shares held
- 23.6M
- +230.2K (+1.0%) vs. Q3 2025
- Total value
- $13.7B
- +$3.02B (+28.2%) vs. Q3 2025
- New holders
- 85
- 137 more added
- Sold out
- 41
- 113 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MDGL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 414 | $12.7B |
| Q1 2026 | 380 | $12.4B |
| Q4 2025 | 387 | $13.7B |
| Q3 2025 | 352 | $10.7B |
| Q2 2025 | 305 | $7.13B |
| Q1 2025 | 321 | $7.85B |
| Q4 2024 | 283 | $7.08B |
| Q3 2024 | 257 | $4.77B |
| Q2 2024 | 257 | $6.41B |
| Q1 2024 | 266 | $5.64B |
| Q4 2023 | 226 | $4.57B |
| Q3 2023 | 206 | $2.54B |
| Q2 2023 | 208 | $3.43B |
| Q1 2023 | 223 | $3.36B |
| Q4 2022 | 189 | $3.86B |
| Q3 2022 | 135 | $763.2M |
| Q2 2022 | 138 | $857.7M |
| Q1 2022 | 140 | $1.20B |
| Q4 2021 | 144 | $1.01B |
| Q3 2021 | 133 | $876.5M |
| Q2 2021 | 151 | $1.09B |
| Q1 2021 | 137 | $1.43B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Madrigal Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Tao Capital Management LP | 21,000 | $12.2M | 10.53% | −20,000−48.8% | Reduced |
| Alliancebernstein L.P. | 21,912 | $12.8M | 0.00% | −13,783−38.6% | Reduced |
| SEI Investments Co | 23,076 | $13.4M | 0.01% | +3,961+20.7% | Added |
| Adage Capital Partners GP, L.L.C. | 23,226 | $13.5M | 0.02% | −65,274−73.8% | Reduced |
| Citigroup Inc | 23,327 | $13.6M | 0.01% | +13,679+141.8% | Added |
| Rhumbline Advisers | 23,691 | $13.8M | 0.01% | −3,572−13.1% | Reduced |
| UBS Asset Management Americas Inc | 23,846 | $13.9M | 0.00% | +370+1.6% | Added |
| First Trust Advisors LP | 24,819 | $14.5M | 0.01% | +21,024+554.0% | Added |
| Emerald Mutual Fund Advisers Trust | 24,996 | $14.6M | 0.71% | −10,095−28.8% | Reduced |
| Rheos Capital Works Inc. | 26,215 | $15.3M | 0.98% | −17,000−39.3% | Reduced |
| Steadfast Capital Management LP | 26,850 | $15.6M | 0.27% | −2,950−9.9% | Reduced |
| Swiss National Bank | 28,580 | $16.6M | 0.01% | +680+2.4% | Added |
| Schroder Investment Management Group | 29,051 | $17.0M | 0.01% | +12,439+74.9% | Added |
| Ameriprise Financial Inc | 29,287 | $17.1M | 0.00% | +16,290+125.3% | Added |
| Groupama Asset Managment | 30,620 | $17.8M | 0.26% | +3,176+11.6% | Added |
| Affinity Asset Advisors, LLC | 31,131 | $18.1M | 1.30% | −83,869−72.9% | Reduced |
| California Public Employees Retirement System | 31,286 | $18.2M | 0.01% | +7,189+29.8% | Added |
| Public Sector Pension Investment Board | 32,871 | $19.1M | 0.06% | +32,871 | New |
| Gilder Gagnon Howe & Co LLC | 33,468 | $19.5M | 0.21% | +2,620+8.5% | Added |
| Segall Bryant & Hamill, LLC | 33,520 | $19.5M | 0.26% | +11,030+49.0% | Added |
| Atika Capital Management LLC | 34,000 | $19.8M | 2.76% | +34,000 | New |
| Citadel Advisors LLC | 36,134 | $21.0M | 0.01% | −12,238−25.3% | Reduced |
| Barclays PLC | 38,720 | $22.5M | 0.01% | −11,192−22.4% | Reduced |
| Emerald Advisers, LLC | 38,913 | $22.7M | 0.70% | −11,824−23.3% | Reduced |
| Marshall Wace, LLP | 39,578 | $23.0M | 0.02% | +38,878+5,554.0% | Added |
| JPMorgan Chase & Co | 40,079 | $23.3M | 0.00% | −7,745−16.2% | Reduced |
| Wells Fargo & Company | 43,457 | $25.3M | 0.00% | +5,639+14.9% | Added |
| Canada Pension Plan Investment Board | 46,120 | $26.9M | 0.02% | +37,120+412.4% | Added |
| Russell Investments Group, Ltd. | 48,159 | $28.0M | 0.03% | +3,274+7.3% | Added |
| EULAV Asset Management | 49,000 | $28.5M | 0.76% | −2,000−3.9% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 50,631 | $29.5M | 0.08% | +53+0.1% | Added |
| Ensign Peak Advisors, Inc | 51,010 | $29.7M | 0.05% | −2,257−4.2% | Reduced |
| Jain Global LLC | 52,721 | $30.7M | 0.30% | +52,721 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 58,295 | $33.9M | 0.09% | −27,478−32.0% | Reduced |
| Candriam Luxembourg S.C.A. | 63,906 | $37.2M | 0.19% | +13,941+27.9% | Added |
| Voya Investment Management LLC | 64,254 | $37.4M | 0.04% | +4,817+8.1% | Added |
| Susquehanna International Group, LLP | 64,466 | $37.5M | 0.05% | −40,352−38.5% | Reduced |
| Raymond James Financial Inc | 66,724 | $38.9M | 0.01% | −3,860−5.5% | Reduced |
| First Light Asset Management, LLC | 66,831 | $38.9M | 2.98% | +55,292+479.2% | Added |
| BNP Paribas Arbitrage, SA | 73,707 | $42.9M | 0.03% | +2,950+4.2% | Added |
| Squarepoint Ops LLC | 74,934 | $43.6M | 0.09% | +44,998+150.3% | Added |
| New York State Common Retirement Fund | 75,933 | $44.2M | 0.06% | +6,660+9.6% | Added |
| ArrowMark Colorado Holdings LLC | 82,624 | $48.1M | 1.06% | −40,635−33.0% | Reduced |
| Renaissance Technologies LLC | 83,862 | $48.8M | 0.08% | −36,820−30.5% | Reduced |
| Tri Locum Partners LP | 86,023 | $50.1M | 6.50% | +18,317+27.1% | Added |
| Franklin Resources Inc | 86,076 | $50.1M | 0.01% | +10,506+13.9% | Added |
| D. E. Shaw & Co., Inc. | 88,554 | $51.6M | 0.04% | −7,628−7.9% | Reduced |
| Jane Street Group, LLC | 93,114 | $54.2M | 0.06% | −2,620−2.7% | Reduced |
| MPM Oncology Impact Management LP | 96,780 | $56.4M | 6.45% | −3,635−3.6% | Reduced |
| UBS Group AG | 102,641 | $59.8M | 0.01% | −114,702−52.8% | Reduced |
| Driehaus Capital Management LLC | 111,666 | $65.0M | 0.44% | −4,308−3.7% | Reduced |
| Nuveen, LLC | 118,363 | $68.9M | 0.02% | +44,648+60.6% | Added |
| Woodline Partners LP | 125,659 | $73.2M | 0.28% | +21,812+21.0% | Added |
| Point72 Asset Management, L.P. | 126,435 | $73.6M | 0.12% | +85,202+206.6% | Added |
| Bank of New York Mellon Corp | 136,869 | $79.7M | 0.01% | +39,090+40.0% | Added |
| Rock Springs Capital Management LP | 139,618 | $81.3M | 4.17% | +1,872+1.4% | Added |
| Erste Asset Management GmbH | 141,100 | $82.3M | 0.69% | −60,000−29.8% | Reduced |
| Morgan Stanley | 150,462 | $87.6M | 0.01% | −99,185−39.7% | Reduced |
| Northern Trust Corp | 151,802 | $88.4M | 0.01% | −8,186−5.1% | Reduced |
| Fiera Capital Corp | 169,456 | $98.7M | 0.31% | +41,656+32.6% | Added |
| Pictet Asset Management Holding SA | 181,949 | $106.0M | 0.10% | −9,847−5.1% | Reduced |
| American Century Companies Inc | 185,116 | $107.8M | 0.05% | +19,501+11.8% | Added |
| Deutsche Bank AG | 192,109 | $111.9M | 0.04% | +154,767+414.5% | Added |
| Norges Bank | 196,393 | $114.4M | 0.01% | +196,393 | New |
| Artisan Partners Limited Partnership | 198,693 | $115.7M | 0.18% | −7,561−3.7% | Reduced |
| Charles Schwab Investment Management Inc | 219,099 | $127.6M | 0.02% | +5,447+2.5% | Added |
| Alkeon Capital Management LLC | 240,000 | $139.8M | 0.61% | +120,000+100.0% | Added |
| Lord, Abbett & Co. LLC | 244,796 | $142.6M | 0.44% | +142,653+139.7% | Added |
| Hood River Capital Management LLC | 247,560 | $144.2M | 1.58% | +4,752+2.0% | Added |
| Armistice Capital, LLC | 265,705 | $154.7M | 3.79% | +145,723+121.5% | Added |
| Polar Capital Holdings Plc | 270,151 | $157.3M | 0.72% | +4,997+1.9% | Added |
| Goldman Sachs Group Inc | 305,847 | $178.1M | 0.03% | −80,253−20.8% | Reduced |
| Price T Rowe Associates Inc | 313,659 | $182.7M | 0.02% | −38,861−11.0% | Reduced |
| William Blair Investment Management, LLC | 354,220 | $206.3M | 0.58% | −57,582−14.0% | Reduced |
| Invesco Ltd. | 365,314 | $212.7M | 0.02% | +65,749+21.9% | Added |
| Bank of America Corp | 416,025 | $242.3M | 0.02% | +171,733+70.3% | Added |
| FMR LLC | 439,398 | $255.9M | 0.01% | +38,262+9.5% | Added |
| Geode Capital Management, LLC | 451,743 | $263.1M | 0.02% | +5,510+1.2% | Added |
| Wellington Management Group LLP | 461,402 | $268.7M | 0.05% | +56,947+14.1% | Added |
| State Street Corp | 583,003 | $339.5M | 0.01% | −75,094−11.4% | Reduced |
| Janus Henderson Group PLC | 1,584,843 | $918.2M | 0.41% | −257,847−14.0% | Reduced |
| BlackRock, Inc. | 1,644,750 | $957.8M | 0.02% | +85,038+5.5% | Added |
| Paulson & Co. Inc. | 1,707,522 | $994.4M | 30.48% | −200,001−10.5% | Reduced |
| Avoro Capital Advisors LLC | 1,807,500 | $1.05B | 10.35% | −25,500−1.4% | Reduced |
| Vanguard Group Inc | 1,808,894 | $1.05B | 0.02% | −3,160−0.2% | Reduced |
| RTW Investments, LP | 1,993,687 | $1.16B | 11.63% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 2,141,701 | $1.25B | 7.30% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −82,401−100.0% | Sold out |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −75,000−100.0% | Sold out |
| Iron Triangle Partners LP | 0 | $0 | 0.00% | −58,378−100.0% | Sold out |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −32,662−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −13,493−100.0% | Sold out |
| University of Wisconsin Foundation | 0 | $0 | 0.00% | −13,007−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −2,588−100.0% | Sold out |
| First National Trust Co | 0 | $0 | 0.00% | −2,476−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −2,318−100.0% | Sold out |
| Toroso Investments, LLC | 0 | $0 | 0.00% | −2,209−100.0% | Sold out |
| Sigma Planning Corp | 0 | $0 | 0.00% | −2,000−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −1,739−100.0% | Sold out |
| R Squared Ltd | 0 | $0 | 0.00% | −1,619−100.0% | Sold out |