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Madrigal Pharmaceuticals, Inc.

MDGL
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001157601

In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 3 sales; 414 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Madrigal Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
387
+44 vs. Q3 2025
Shares held
23.6M
+230.2K (+1.0%) vs. Q3 2025
Total value
$13.7B
+$3.02B (+28.2%) vs. Q3 2025
New holders
85
137 more added
Sold out
41
113 more reduced

9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MDGL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 387 institutions
Q1 2021: 137 institutionsQ2 2021: 151 institutionsQ3 2021: 133 institutionsQ4 2021: 144 institutionsQ1 2022: 140 institutionsQ2 2022: 138 institutionsQ3 2022: 135 institutionsQ4 2022: 189 institutionsQ1 2023: 223 institutionsQ2 2023: 208 institutionsQ3 2023: 206 institutionsQ4 2023: 226 institutionsQ1 2024: 266 institutionsQ2 2024: 257 institutionsQ3 2024: 257 institutionsQ4 2024: 283 institutionsQ1 2025: 321 institutionsQ2 2025: 305 institutionsQ3 2025: 352 institutionsQ4 2025: 387 institutionsQ1 2026: 380 institutionsQ2 2026: 414 institutions
Value heldQ4 2025: $13.7B
Q1 2021: $1.43BQ2 2021: $1.09BQ3 2021: $876.5MQ4 2021: $1.01BQ1 2022: $1.20BQ2 2022: $857.7MQ3 2022: $763.2MQ4 2022: $3.86BQ1 2023: $3.36BQ2 2023: $3.43BQ3 2023: $2.54BQ4 2023: $4.57BQ1 2024: $5.64BQ2 2024: $6.41BQ3 2024: $4.77BQ4 2024: $7.08BQ1 2025: $7.85BQ2 2025: $7.13BQ3 2025: $10.7BQ4 2025: $13.7BQ1 2026: $12.4BQ2 2026: $12.7B
Institutions holding MDGL and their total value by quarter
QuarterHoldersValue
Q2 2026414$12.7B
Q1 2026380$12.4B
Q4 2025387$13.7B
Q3 2025352$10.7B
Q2 2025305$7.13B
Q1 2025321$7.85B
Q4 2024283$7.08B
Q3 2024257$4.77B
Q2 2024257$6.41B
Q1 2024266$5.64B
Q4 2023226$4.57B
Q3 2023206$2.54B
Q2 2023208$3.43B
Q1 2023223$3.36B
Q4 2022189$3.86B
Q3 2022135$763.2M
Q2 2022138$857.7M
Q1 2022140$1.20B
Q4 2021144$1.01B
Q3 2021133$876.5M
Q2 2021151$1.09B
Q1 2021137$1.43B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Madrigal Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding MDGL in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Mariner, LLC2,426$1.41M0.00%+605+33.2%Added
Bamco Inc2,500$1.46M0.00%−100−3.8%Reduced
Strid Group, LLC2,500$1.46M0.18%00.0%Unchanged
Quadrant Capital Group LLC2,605$1.52M0.05%00.0%Unchanged
Aigen Investment Management, LP2,652$1.54M0.36%+2,067+353.3%Added
Ami Asset Management Corp2,752$1.60M0.09%−674−19.7%Reduced
XTX Topco Ltd2,819$1.64M0.04%+2,819New
HighVista Strategies LLC2,839$1.65M0.43%−698−19.7%Reduced
Dana Investment Advisors, Inc.2,866$1.67M0.05%−315−9.9%Reduced
Teachers Retirement System of the State of Kentucky2,872$1.67M0.01%00.0%Unchanged
Bellevue Group AG2,884$1.68M0.03%+491+20.5%Added
Penn Capital Management Co Inc2,902$1.72M0.14%+2,902New
Zurcher Kantonalbank (Zurich Cantonalbank)2,978$1.73M0.00%+855+40.3%Added
Advisor Group Holdings, Inc.3,050$1.78M0.00%+2,248+280.3%Added
KLP Kapitalforvaltning AS3,240$1.89M0.01%+240+8.0%Added
STRS Ohio3,300$1.92M0.01%+1,100+50.0%Added
Sphera Funds Management Ltd.3,300$1.92M0.40%+3,300New
Farallon Capital Management, L.L.C.3,319$1.93M0.01%00.0%Unchanged
Martingale Asset Management L P3,386$1.97M0.05%−1,129−25.0%Reduced
Newbridge Financial Services Group, Inc.3,548$2.07M0.32%−94−2.6%Reduced
Allworth Financial LP3,558$2.07M0.01%+10+0.3%Added
Brevan Howard Capital Management LP3,632$2.12M0.04%+2,257+164.1%Added
Cinctive Capital Management LP3,687$2.15M0.12%+81+2.2%Added
China Universal Asset Management Co., Ltd.3,701$2.16M0.17%−206−5.3%Reduced
Knights of Columbus Asset Advisors LLC3,702$2.16M0.12%−146−3.8%Reduced
DekaBank Deutsche Girozentrale8,000$2.25M0.00%00.0%Unchanged
Moody Aldrich Partners LLC3,876$2.26M0.42%+3,876New
Cetera Investment Advisers3,941$2.30M0.00%+215+5.8%Added
Acadian Asset Management LLC3,958$2.30M0.00%+3,958New
Shikiar Asset Management Inc4,000$2.33M0.58%00.0%Unchanged
Arizona State Retirement System4,040$2.35M0.01%−215−5.1%Reduced
Los Angeles Capital Management LLC5,603$2.40M0.01%+479+9.3%Added
Profund Advisors LLC4,157$2.42M0.07%−45−1.1%Reduced
HRT Financial LP4,218$2.46M0.01%+4,218New
ProShare Advisors LLC4,449$2.59M0.00%+475+12.0%Added
Peak Financial Advisors LLC4,466$2.60M1.17%+3,312+287.0%Added
Pathstone Holdings, LLC4,733$2.76M0.01%+2,297+94.3%Added
State Board of Administration of Florida Retirement System4,759$2.77M0.00%+150+3.3%Added
Assetmark, Inc4,810$2.80M0.01%−248−4.9%Reduced
Police & Firemen's Retirement System of New Jersey5,016$2.92M0.02%−149−2.9%Reduced
State of New Jersey Common Pension Fund D5,044$2.94M0.01%−181−3.5%Reduced
O'Neil Global Advisors, Inc.5,060$2.95M1.01%+5,060New
Handelsbanken Fonder AB5,080$2.96M0.01%+680+15.5%Added
Fieldview Capital Management, LLC5,196$3.03M0.51%+538+11.6%Added
Tudor Investment Corp Et Al5,285$3.08M0.02%+4,359+470.7%Added
Brinker Capital Investments, LLC5,350$3.12M0.02%+1,259+30.8%Added
Assenagon Asset Management S.A.5,390$3.14M0.00%+5,390New
Prudential Financial Inc5,675$3.30M0.00%−238−4.0%Reduced
F/M Investments LLC5,738$3.34M0.13%−584−9.2%Reduced
Victory Capital Management Inc5,822$3.39M0.00%+59+1.0%Added
Susquehanna Portfolio Strategies, LLC6,250$3.64M0.06%00.0%Unchanged
SG Americas Securities, LLC6,386$3.72M0.00%+1,195+23.0%Added
Calamos Advisors LLC6,566$3.82M0.02%+2,081+46.4%Added
Capricorn Fund Managers Ltd6,600$3.84M0.93%+6,600New
Entropy Technologies, LP6,942$4.04M0.22%+3,240+87.5%Added
Millennium Management LLC6,978$4.06M0.00%+5,180+288.1%Added
PFM Health Sciences, LP7,258$4.23M0.43%+7,258New
Principal Financial Group Inc7,261$4.23M0.00%−4,807−39.8%Reduced
Intech Investment Management LLC7,301$4.25M0.04%+631+9.5%Added
Trexquant Investment LP7,784$4.53M0.04%+7,784New
Hennion & Walsh Asset Management, Inc.8,163$4.75M0.16%−4,684−36.5%Reduced
Engineers Gate Manager LP8,708$5.07M0.06%+5,774+196.8%Added
Verition Fund Management LLC8,893$5.18M0.03%+3,263+58.0%Added
Algert Global LLC8,970$5.22M0.08%+940+11.7%Added
State of Wisconsin Investment Board9,276$5.40M0.01%−1,599−14.7%Reduced
AQR Capital Management LLC10,006$5.83M0.00%+3,420+51.9%Added
Royal Bank of Canada10,223$5.95M0.00%−9,950−49.3%Reduced
MetLife Investment Management10,237$5.96M0.03%−570−5.3%Reduced
TD Asset Management Inc10,386$6.05M0.00%−2,938−22.1%Reduced
EFG International AG10,373$6.05M0.12%+10,373New
Rafferty Asset Management, LLC10,530$6.13M0.02%−8,185−43.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.10,561$6.15M0.01%−795−7.0%Reduced
Resolute Capital Asset Partners LLC10,918$6.36M3.07%−4,082−27.2%Reduced
Creative Planning11,141$6.49M0.00%+2,711+32.2%Added
Voleon Capital Management LP11,235$6.54M0.14%+11,235New
Nomura Asset Management International Inc.11,592$6.75M0.01%+11,592New
Nan Fung Group Holdings Ltd11,872$6.91M6.19%00.0%Unchanged
IMC-Chicago, LLC12,051$7.02M0.12%+12,051New
Mutual of America Capital Management LLC12,100$7.05M0.07%−79−0.6%Reduced
Journey Strategic Wealth LLC12,829$7.47M0.20%+10.0%Added
EAM Investors, LLC12,837$7.48M0.83%+1,993+18.4%Added
Skandinaviska Enskilda Banken AB (publ)13,450$7.84M0.03%−4,913−26.8%Reduced
California State Teachers Retirement System14,008$8.16M0.01%+117+0.8%Added
Castleark Management LLC14,466$8.42M0.25%+4,540+45.7%Added
Man Group plc14,764$8.60M0.02%−6,564−30.8%Reduced
Legal & General Group Plc15,231$8.87M0.00%−6,440−29.7%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.15,347$8.94M0.01%+15,210+11,102.2%Added
Envestnet Asset Management Inc15,372$8.95M0.00%+806+5.5%Added
Manufacturers Life Insurance Company, The16,052$9.36M0.01%−1,275−7.4%Reduced
Federated Hermes, Inc.16,325$9.51M0.02%+12,440+320.2%Added
LPL Financial LLC16,542$9.63M0.00%−5,996−26.6%Reduced
WCM Investment Management, LLC17,254$10.1M0.02%−1,037−5.7%Reduced
StemPoint Capital LP17,736$10.3M1.77%+9,529+116.1%Added
Neuberger Berman Group LLC18,660$10.9M0.01%+129+0.7%Added
Universal- Beteiligungs- und Servicegesellschaft mbH19,076$11.1M0.02%+3,788+24.8%Added
Bridgewater Associates, LP19,218$11.2M0.04%−8,567−30.8%Reduced
Jump Financial, LLC19,221$11.2M0.14%−1,735−8.3%Reduced
Dimensional Fund Advisors LP19,321$11.3M0.00%+13,522+233.2%Added
Rhenman & Partners Asset Management AB19,550$11.4M1.06%+1,300+7.1%Added
Rockefeller Capital Management L.P.19,661$11.4M0.02%+1,210+6.6%Added