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Madrigal Pharmaceuticals, Inc.

MDGL
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001157601

In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 3 sales; 414 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Madrigal Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
387
+44 vs. Q3 2025
Shares held
23.6M
+230.2K (+1.0%) vs. Q3 2025
Total value
$13.7B
+$3.02B (+28.2%) vs. Q3 2025
New holders
85
137 more added
Sold out
41
113 more reduced

9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MDGL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 387 institutions
Q1 2021: 137 institutionsQ2 2021: 151 institutionsQ3 2021: 133 institutionsQ4 2021: 144 institutionsQ1 2022: 140 institutionsQ2 2022: 138 institutionsQ3 2022: 135 institutionsQ4 2022: 189 institutionsQ1 2023: 223 institutionsQ2 2023: 208 institutionsQ3 2023: 206 institutionsQ4 2023: 226 institutionsQ1 2024: 266 institutionsQ2 2024: 257 institutionsQ3 2024: 257 institutionsQ4 2024: 283 institutionsQ1 2025: 321 institutionsQ2 2025: 305 institutionsQ3 2025: 352 institutionsQ4 2025: 387 institutionsQ1 2026: 380 institutionsQ2 2026: 414 institutions
Value heldQ4 2025: $13.7B
Q1 2021: $1.43BQ2 2021: $1.09BQ3 2021: $876.5MQ4 2021: $1.01BQ1 2022: $1.20BQ2 2022: $857.7MQ3 2022: $763.2MQ4 2022: $3.86BQ1 2023: $3.36BQ2 2023: $3.43BQ3 2023: $2.54BQ4 2023: $4.57BQ1 2024: $5.64BQ2 2024: $6.41BQ3 2024: $4.77BQ4 2024: $7.08BQ1 2025: $7.85BQ2 2025: $7.13BQ3 2025: $10.7BQ4 2025: $13.7BQ1 2026: $12.4BQ2 2026: $12.7B
Institutions holding MDGL and their total value by quarter
QuarterHoldersValue
Q2 2026414$12.7B
Q1 2026380$12.4B
Q4 2025387$13.7B
Q3 2025352$10.7B
Q2 2025305$7.13B
Q1 2025321$7.85B
Q4 2024283$7.08B
Q3 2024257$4.77B
Q2 2024257$6.41B
Q1 2024266$5.64B
Q4 2023226$4.57B
Q3 2023206$2.54B
Q2 2023208$3.43B
Q1 2023223$3.36B
Q4 2022189$3.86B
Q3 2022135$763.2M
Q2 2022138$857.7M
Q1 2022140$1.20B
Q4 2021144$1.01B
Q3 2021133$876.5M
Q2 2021151$1.09B
Q1 2021137$1.43B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Madrigal Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding MDGL in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Prelude Capital Management, LLC430$250.4K0.02%+430New
Skopos Labs, Inc.427$251.7K0.01%+427New
SummitTX Capital, L.P.433$252.2K0.01%+433New
Amundi437$254.5K0.00%+437New
US Bancorp441$256.8K0.00%+53+13.7%Added
GF Fund Management Co. Ltd.445$259.1K0.00%−35−7.3%Reduced
Kestra Investment Management, LLC445$259.1K0.01%+3+0.7%Added
IFP Advisors, Inc461$268.5K0.01%+90+24.3%Added
Soleus Capital Management, L.P.500$291.2K0.01%−67,836−99.3%Reduced
Wiley Bros.-Aintree Capital, LLC509$296.4K0.00%+509New
TCI Wealth Advisors, Inc.517$301.1K0.02%00.0%Unchanged
Resources Investment Advisors, LLC.519$302.2K0.00%−97−15.7%Reduced
James J. Burns & Company, LLC532$309.8K0.04%+532New
Private Advisor Group, LLC536$312.1K0.00%+536New
Everence Capital Management Inc540$314.0K0.02%00.0%Unchanged
Integrated Investment Consultants, LLC567$330.2K0.06%00.0%Unchanged
Truist Financial Corp569$331.4K0.00%−34−5.6%Reduced
Amalgamated Bank584$340.0K0.00%−19−3.2%Reduced
EP Wealth Advisors, LLC609$354.8K0.00%+609New
Tower Research Capital LLC (TRC)612$356.4K0.01%+255+71.4%Added
JGP Global Gestao de Recursos Ltda.625$364.0K0.22%−417−40.0%Reduced
Cary Street Partners Financial LLC628$365.7K0.01%+628New
M&T Bank Corp629$365.9K0.00%+629New
Allspring Global Investments Holdings, LLC631$374.7K0.00%+631New
Advisory Services Network, LLC658$383.2K0.01%+658New
Swiss Life Asset Management Ltd690$401.8K0.00%+44+6.8%Added
Glenmede Trust Co NA691$402.4K0.00%+691New
Cannon Global Investment Management, LLC700$407.6K1.08%−100−12.5%Reduced
Miracle Mile Advisors, LLC703$409.4K0.01%00.0%Unchanged
Centaurus Financial, Inc.709$413.0K0.02%00.0%Unchanged
Abel Hall, LLC710$413.5K0.10%+120+20.3%Added
Eurizon Capital SGR S.p.A.729$424.8K0.00%+729New
Comerica Bank743$433.1K0.00%−16−2.1%Reduced
Dorsey & Whitney Trust CO LLC752$437.9K0.02%00.0%Unchanged
Vise Technologies, Inc.769$447.8K0.01%+769New
Chicago Partners Investment Group LLC961$461.7K0.01%−64−6.2%Reduced
Virginia Retirement Systems Et Al800$465.9K0.00%+800New
Vestmark Advisory Solutions, Inc.806$469.4K0.01%+806New
PharVision Advisers, LLC813$473.4K0.24%+231+39.7%Added
CIBC Asset Management Inc816$475.2K0.00%+190+30.4%Added
Mount Yale Investment Advisors, LLC824$479.8K0.02%+824New
QRG Capital Management, Inc.834$485.7K0.01%+63+8.2%Added
IFG Advisory, LLC844$491.5K0.02%+844New
Intrust Bank NA848$493.8K0.04%+174+25.8%Added
Park Avenue Securities LLC858$499.0K0.00%+72+9.2%Added
PSP Research LLC892$519.4K0.45%+892New
ADAR1 Capital Management, LLC895$521.2K0.04%−4,000−81.7%Reduced
Baader Bank INC902$524.8K0.04%−1,033−53.4%Reduced
Syon Capital LLC965$562.0K0.03%00.0%Unchanged
Atria Investments LLC988$575.4K0.01%−22−2.2%Reduced
Optimize Financial Inc992$577.7K0.29%+12+1.2%Added
Blair William & Co1,000$582.3K0.00%00.0%Unchanged
Cynosure Management, LLC1,025$596.9K0.06%+1,025New
Natixis1,041$606.2K0.00%+1,041New
Graham Capital Management, L.P.1,062$618.4K0.02%+1,062New
Pier 88 Investment Partners LLC1,080$628.9K0.14%+1,080New
Landscape Capital Management, L.L.C.1,088$633.6K0.04%+78+7.7%Added
HSBC Holdings PLC1,100$646.2K0.00%+1,100New
Captrust Financial Advisors1,131$658.6K0.00%+565+99.8%Added
Verity Asset Management, Inc.1,158$674.4K0.29%−102−8.1%Reduced
Everhart Financial Group, Inc.1,163$677.3K0.06%+704+153.4%Added
HighTower Advisors, LLC1,173$683.1K0.00%+46+4.1%Added
Virtus Investment Advisers, Inc.1,194$695.3K0.19%−301−20.1%Reduced
Cambridge Investment Research Advisors, Inc.1,198$698.0K0.00%−73−5.7%Reduced
B. Metzler seel. Sohn & Co. AG1,221$711.0K0.01%00.0%Unchanged
CIBC World Markets Corp1,231$716.9K0.00%+1,231New
Federation des caisses Desjardins du Quebec1,246$725.6K0.00%+162+14.9%Added
JustInvest LLC1,249$727.3K0.01%+160+14.7%Added
O'Shaughnessy Asset Management, LLC1,283$747.1K0.00%+427+49.9%Added
Oppenheimer Asset Management Inc.1,313$764.6K0.01%+207+18.7%Added
Two Sigma Securities, LLC1,336$778.0K0.11%+1,336New
Sanctuary Advisors, LLC1,371$798.4K0.00%−94−6.4%Reduced
New York Life Investment Management LLC1,386$807.1K0.01%−224−13.9%Reduced
Public Employees Retirement Association of Colorado1,433$834.0K0.00%00.0%Unchanged
Cerity Partners LLC1,444$840.9K0.00%+481+49.9%Added
Wealth Enhancement Advisory Services, LLC1,513$844.3K0.00%+805+113.7%Added
Xponance, Inc.1,463$852.0K0.01%+3+0.2%Added
AlTi Global, Inc.1,493$869.4K0.02%+1+0.1%Added
Ameritas Investment Partners, Inc.1,536$894.5K0.03%−18−1.2%Reduced
J. Safra Sarasin Holding AG1,546$900.3K0.01%−851−35.5%Reduced
NEOS Investment Management LLC1,571$914.9K0.01%−50−3.1%Reduced
Tema ETFs LLC1,571$914.9K0.07%−50−3.1%Reduced
Kestra Advisory Services, LLC1,580$920.1K0.00%+13+0.8%Added
Great West Life Assurance Co1,608$937.0K0.00%00.0%Unchanged
MML Investors Services, LLC1,668$971.3K0.00%+278+20.0%Added
Seven Fleet Capital Management LP1,860$1.08M0.73%+1,860New
CWM, LLC1,875$1.09M0.00%−485−20.6%Reduced
Illinois Municipal Retirement Fund1,903$1.11M0.01%+1,903New
FORA Capital, LLC1,997$1.16M0.14%−506−20.2%Reduced
Knott David M Jr2,000$1.16M0.54%00.0%Unchanged
Toth Financial Advisory Corp2,000$1.16M0.13%+2,000New
D.A. Davidson & Co.2,129$1.24M0.01%+58+2.8%Added
Teacher Retirement System of Texas2,151$1.25M0.00%−1,380−39.1%Reduced
Guggenheim Capital LLC2,161$1.26M0.01%+536+33.0%Added
Snowden Capital Advisors LLC2,225$1.30M0.03%−285−11.4%Reduced
CWM Advisors, LLC2,256$1.31M0.12%+2,256New
Jefferies Financial Group Inc.2,300$1.34M0.01%+2,300New
Stifel Financial Corp2,327$1.36M0.00%−282−10.8%Reduced
Commonwealth Equity Services, LLC2,342$1.36M0.00%−135−5.5%Reduced
Allianz Asset Management GmbH2,400$1.40M0.00%−700−22.6%Reduced