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Maze Therapeutics, Inc.

MAZE
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001842295

In the last 90 days, Maze Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 161 institutions reported holding it in 13F filings for Q2 2026, worth $1.75B in total; HHLR Advisors (Hillhouse) is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Maze Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
161
−1 vs. Q1 2026
Shares held
58.5M
+9.72M (+19.9%) vs. Q1 2026
Total value
$1.75B
+$287.9M (+19.8%) vs. Q1 2026
New holders
38
66 more added
Sold out
39
38 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MAZE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 161 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 68 institutionsQ2 2025: 75 institutionsQ3 2025: 94 institutionsQ4 2025: 143 institutionsQ1 2026: 165 institutionsQ2 2026: 161 institutions
Value heldQ2 2026: $1.75B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $441.4MQ2 2025: $476.7MQ3 2025: $1.11BQ4 2025: $2.00BQ1 2026: $1.54BQ2 2026: $1.75B
Institutions holding MAZE and their total value by quarter
QuarterHoldersValue
Q2 2026161$1.75B
Q1 2026165$1.54B
Q4 2025143$2.00B
Q3 202594$1.11B
Q2 202575$476.7M
Q1 202568$441.4M
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Maze Therapeutics, Inc.; share changes are against Q1 2026.

Institutions holding MAZE in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
UBS Group AG84,679$2.53M0.00%−9,219−9.8%Reduced
Algert Global LLC93,357$2.79M0.03%+93,357New
Bank of New York Mellon Corp97,588$2.91M0.00%+23,320+31.4%Added
Alyeska Investment Group, L.P.100,000$2.98M0.01%00.0%Unchanged
Ensign Peak Advisors, Inc101,644$3.03M0.00%−84,150−45.3%Reduced
Exome Asset Management LLC114,692$3.42M2.11%+26,182+29.6%Added
Walleye Capital LLC128,006$3.82M0.02%+100,061+358.1%Added
Qube Research & Technologies Ltd131,043$3.91M0.00%−3,907−2.9%Reduced
Price T Rowe Associates Inc132,870$3.96M0.00%+10,175+8.3%Added
Morgan Stanley135,168$4.03M0.00%−69,663−34.0%Reduced
HighVista Strategies LLC136,572$4.08M0.93%+36,722+36.8%Added
SummitTX Capital, L.P.176,291$5.26M0.14%+92,541+110.5%Added
ExodusPoint Capital Management, LP183,264$5.47M0.05%+183,264New
Boothbay Fund Management, LLC188,857$5.64M0.11%−95,619−33.6%Reduced
Two Sigma Investments, LP192,952$5.76M0.00%+177,107+1,117.7%Added
Schroder Investment Management Group199,872$5.80M0.00%+162,691+437.6%Added
RTW Investments, LP212,000$6.33M0.05%+212,000New
Vanguard Fiduciary Trust Co219,938$6.56M0.00%+68,938+45.7%Added
Ameriprise Financial Inc227,425$6.79M0.00%+119,939+111.6%Added
Mass General Brigham, Inc239,994$7.16M1.98%00.0%Unchanged
Adage Capital Partners GP, L.L.C.248,000$7.40M0.01%−930,000−78.9%Reduced
Charles Schwab Investment Management Inc260,566$7.78M0.00%+74,133+39.8%Added
Hudson Bay Capital Management LP270,000$8.06M0.04%+261,850+3,212.9%Added
Candriam Luxembourg S.C.A.273,932$8.17M0.04%−4,235−1.5%Reduced
Goldman Sachs Group Inc293,144$8.75M0.00%+13,431+4.8%Added
Northern Trust Corp294,742$8.80M0.00%+83,360+39.4%Added
Bank of America Corp321,227$9.59M0.00%+126,143+64.7%Added
Squadron Capital Management LLC335,000$10.0M3.42%+77,500+30.1%Added
ADAR1 Capital Management, LLC339,276$10.1M0.48%+289,181+577.3%Added
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)366,028$10.9M1.31%00.0%Unchanged
Ikarian Capital, LLC378,999$11.3M1.85%00.0%Unchanged
Standard Life Aberdeen plc383,773$11.5M0.02%+157,546+69.6%Added
Vanguard Portfolio Management LLC393,107$11.7M0.00%+197,565+101.0%Added
Sphera Funds Management Ltd.417,564$12.5M1.78%+190,221+83.7%Added
Bessemer Group Inc481,790$14.4M0.02%00.0%Unchanged
Woodline Partners LP736,216$22.0M0.07%+85,987+13.2%Added
ArrowMark Colorado Holdings LLC767,383$22.9M0.95%00.0%Unchanged
Casdin Capital, LLC843,857$25.2M1.26%+85,000+11.2%Added
Citadel Advisors LLC852,676$25.4M0.01%+76,962+9.9%Added
Geode Capital Management, LLC858,054$25.6M0.00%+258,087+43.0%Added
Marshall Wace, LLP914,572$27.3M0.02%+603,933+194.4%Added
JPMorgan Chase & Co964,011$28.0M0.00%+905,565+1,549.4%Added
TRV GP V, LLC950,800$28.4M5.69%00.0%Unchanged
Driehaus Capital Management LLC954,886$28.5M0.17%+318,724+50.1%Added
State Street Corp997,533$29.8M0.00%+360,811+56.7%Added
General Catalyst Group Management, LLC1,035,910$30.9M16.40%00.0%Unchanged
FMR LLC1,056,959$31.5M0.00%+192,745+22.3%Added
Farallon Capital Management, L.L.C.1,107,814$33.1M0.19%+734,814+197.0%Added
Braidwell LP1,140,040$34.0M1.26%+1,140,040New
Alphabet Inc.1,388,583$41.4M0.04%00.0%Unchanged
VR Adviser, LLC1,602,034$47.8M1.45%00.0%Unchanged
AH Capital Management, L.L.C.1,702,225$50.8M0.36%00.0%Unchanged
Vanguard Capital Management LLC1,778,222$53.1M0.00%+342,566+23.9%Added
Logos Global Management LP1,935,000$57.7M2.49%+700,000+56.7%Added
T. Rowe Price Investment Management, Inc.2,603,682$77.7M0.05%+2,603,682New
Jupiter Topco LLC3,408,045$101.8M0.04%+3,408,045New
BlackRock, Inc.3,502,841$104.5M0.00%+932,416+36.3%Added
Deep Track Capital, LP3,732,569$111.4M1.64%+255,007+7.3%Added
ARCH Venture Management, LLC4,120,053$123.0M11.18%00.0%Unchanged
TRV GP IV, LLC4,473,958$133.5M52.63%00.0%Unchanged
Frazier Life Sciences Management, L.P.5,032,915$150.2M3.27%+465,641+10.2%Added
Paradigm Biocapital Advisors LP0$00.00%−2,744,399−100.0%Sold out
Cormorant Asset Management, LP0$00.00%−750,000−100.0%Sold out
Caligan Partners LP0$00.00%−614,962−100.0%Sold out
Washington University0$00.00%−280,802−100.0%Sold out
Freestone Grove Partners LP0$00.00%−234,953−100.0%Sold out
Spruce Street Capital LP0$00.00%−200,000−100.0%Sold out
Foresite Capital Management IV, LLC0$00.00%−156,901−100.0%Sold out
Holocene Advisors, LP0$00.00%−136,168−100.0%Sold out
Atika Capital Management LLC0$00.00%−111,500−100.0%Sold out
Integral Health Asset Management, LLC0$00.00%−100,000−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−34,977−100.0%Sold out
Parkman Healthcare Partners LLC0$00.00%−31,844−100.0%Sold out
Twinbeech Capital LP0$00.00%−30,989−100.0%Sold out
Seven Fleet Capital Management LP0$00.00%−30,707−100.0%Sold out
Millennium Management LLC0$00.00%−29,892−100.0%Sold out
Foresite Capital Management V, LLC0$00.00%−25,905−100.0%Sold out
Blackstone Group Inc.0$00.00%−24,990−100.0%Sold out
Acuta Capital Partners, LLC0$00.00%−19,335−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−18,127−100.0%Sold out
Gilder Gagnon Howe & Co LLC0$00.00%−17,487−100.0%Sold out
Renaissance Technologies LLC0$00.00%−15,800−100.0%Sold out
Diadema Partners LP0$00.00%−15,000−100.0%Sold out
Ground Swell Capital, LLC0$00.00%−13,609−100.0%Sold out
American Century Companies Inc0$00.00%−9,635−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−9,139−100.0%Sold out
Voleon Capital Management LP0$00.00%−7,287−100.0%Sold out
Mangrove Partners0$00.00%−6,748−100.0%Sold out
STRS Ohio0$00.00%−6,300−100.0%Sold out
Caption Management, LLC0$00.00%−5,000−100.0%Sold out
Federated Hermes, Inc.0$00.00%−1,097−100.0%Sold out
Kemnay Advisory Services Inc.0$00.00%−306−100.0%Sold out
SMA Capital LLC0$00.00%−134−100.0%Sold out
Larson Financial Group LLC0$00.00%−6−100.0%Sold out
MAI Capital Management0$00.00%−5−100.0%Sold out
True Wealth Design, LLC0$00.00%−5−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−4−100.0%Sold out
Rachor Investment Advisory Services, LLC0$00.00%−3−100.0%Sold out
Stone House Investment Management, LLC0$00.00%−2−100.0%Sold out
Hughes Financial Services, LLC0$00.00%−1−100.0%Sold out