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INSMED Inc

INSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001104506

In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q4 2025

Institutional positions in INSMED Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
678
+121 vs. Q3 2025
Shares held
217.4M
+6.76M (+3.2%) vs. Q3 2025
Total value
$37.8B
+$7.55B (+24.9%) vs. Q3 2025
New holders
202
241 more added
Sold out
81
180 more reduced

9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 678 institutions
Q1 2021: 199 institutionsQ2 2021: 203 institutionsQ3 2021: 193 institutionsQ4 2021: 214 institutionsQ1 2022: 224 institutionsQ2 2022: 214 institutionsQ3 2022: 238 institutionsQ4 2022: 225 institutionsQ1 2023: 230 institutionsQ2 2023: 223 institutionsQ3 2023: 252 institutionsQ4 2023: 271 institutionsQ1 2024: 288 institutionsQ2 2024: 378 institutionsQ3 2024: 414 institutionsQ4 2024: 439 institutionsQ1 2025: 442 institutionsQ2 2025: 516 institutionsQ3 2025: 566 institutionsQ4 2025: 678 institutionsQ1 2026: 675 institutionsQ2 2026: 667 institutions
Value heldQ4 2025: $37.8B
Q1 2021: $3.63BQ2 2021: $3.46BQ3 2021: $3.40BQ4 2021: $3.36BQ1 2022: $2.97BQ2 2022: $2.55BQ3 2022: $2.74BQ4 2022: $2.87BQ1 2023: $2.48BQ2 2023: $3.09BQ3 2023: $3.72BQ4 2023: $4.64BQ1 2024: $4.07BQ2 2024: $11.7BQ3 2024: $13.7BQ4 2024: $13.3BQ1 2025: $15.3BQ2 2025: $21.2BQ3 2025: $30.3BQ4 2025: $37.8BQ1 2026: $35.7BQ2 2026: $23.8B
Institutions holding INSM and their total value by quarter
QuarterHoldersValue
Q2 2026667$23.8B
Q1 2026675$35.7B
Q4 2025678$37.8B
Q3 2025566$30.3B
Q2 2025516$21.2B
Q1 2025442$15.3B
Q4 2024439$13.3B
Q3 2024414$13.7B
Q2 2024378$11.7B
Q1 2024288$4.07B
Q4 2023271$4.64B
Q3 2023252$3.72B
Q2 2023223$3.09B
Q1 2023230$2.48B
Q4 2022225$2.87B
Q3 2022238$2.74B
Q2 2022214$2.55B
Q1 2022224$2.97B
Q4 2021214$3.36B
Q3 2021193$3.40B
Q2 2021203$3.46B
Q1 2021199$3.63B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q3 2025.

Institutions holding INSM in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Elo Mutual Pension Insurance Co12,409$2.16M0.03%−2,677−17.7%Reduced
October Effect Ltd12,121$2.11M2.32%+12,121New
MYDA Advisors LLC12,000$2.09M0.59%00.0%Unchanged
Emerald Advisers, LLC11,990$2.09M0.06%−403−3.3%Reduced
Arrowpoint Investment Partners (Singapore) Pte. Ltd.11,556$2.01M0.30%+11,556New
JustInvest LLC11,424$1.99M0.02%+1,872+19.6%Added
Osmosis Investment Management UK Ltd11,325$1.97M0.05%+11,325New
Draper Asset Management, LLC11,312$1.97M1.04%+973+9.4%Added
PKO Investment Management Joint-Stock Co11,300$1.97M0.16%+11,300New
Sectoral Asset Management Inc11,182$1.95M1.56%−2,243−16.7%Reduced
Gulf International Bank (UK) Ltd11,033$1.92M0.06%+11,033New
Virtu Financial LLC10,922$1.90M0.07%+10,922New
Wealth Enhancement Advisory Services, LLC10,427$1.83M0.00%+2,829+37.2%Added
Maryland State Retirement & Pension System10,484$1.82M0.04%+1,200+12.9%Added
WCM Investment Management, LLC10,368$1.80M0.00%−5,132−33.1%Reduced
AustralianSuper Pty Ltd10,005$1.74M0.01%+10,005New
Ishara Investments LP10,000$1.74M2.03%+10,000New
Wealthfront Advisers LLC9,991$1.74M0.00%+9,991New
Abn Amro Investment Solutions9,989$1.74M0.03%+9,989New
Jump Financial, LLC9,823$1.71M0.02%+9,823New
AG2R la Mondiale Gestion D'Actifs9,677$1.68M0.07%+9,677New
Yorktown Management & Research Co Inc9,600$1.67M1.34%00.0%Unchanged
Vestmark Advisory Solutions, Inc.9,514$1.66M0.02%+6,966+273.4%Added
Ikarian Capital, LLC9,337$1.63M0.21%−4,414−32.1%Reduced
M&T Bank Corp9,150$1.59M0.01%+5,056+123.5%Added
QRG Capital Management, Inc.9,030$1.57M0.02%+2,610+40.7%Added
Waldron Private Wealth LLC8,810$1.53M0.06%+10+0.1%Added
Dai-Ichi Life Insurance Company, Ltd8,633$1.50M0.04%+8,633New
Highland Capital Management, LLC8,558$1.49M0.07%+8,558New
DekaBank Deutsche Girozentrale50,000$1.49M0.00%00.0%Unchanged
Royal London Asset Management Ltd8,510$1.48M0.00%+8,510New
S&CO Inc8,300$1.44M0.09%00.0%Unchanged
Quantitative Investment Management, LLC8,148$1.42M0.14%+8,148New
FORA Capital, LLC7,942$1.38M0.17%+7,942New
Castleark Management LLC7,790$1.36M0.04%+2,060+36.0%Added
US Bancorp7,748$1.35M0.00%−903−10.4%Reduced
Ameritas Investment Partners, Inc.7,710$1.34M0.04%+7,710New
AlphaCentric Advisors LLC7,588$1.32M1.32%+7,588New
Landscape Capital Management, L.L.C.7,364$1.28M0.09%−20,830−73.9%Reduced
Comerica Bank7,337$1.28M0.01%−154,467−95.5%Reduced
Macquarie Group Ltd7,293$1.27M0.01%−642,554−98.9%Reduced
Wiley Bros.-Aintree Capital, LLC7,259$1.26M0.01%+1,213+20.1%Added
Norinchukin Bank, The7,242$1.26M0.01%+7,242New
Snowden Capital Advisors LLC7,234$1.26M0.03%−535−6.9%Reduced
Colony Group, LLC7,174$1.25M0.00%+2,638+58.2%Added
Himension Fund7,164$1.25M0.08%−1,423−16.6%Reduced
The PNC Financial Services Group, Inc.6,860$1.19M0.00%+49+0.7%Added
Everence Capital Management Inc6,774$1.18M0.07%+331+5.1%Added
North Dakota State Investment Board6,558$1.14M0.04%+6,558New
J. Safra Sarasin Holding AG6,461$1.12M0.02%−1,096−14.5%Reduced
Vise Technologies, Inc.6,314$1.10M0.02%+982+18.4%Added
XTX Topco Ltd6,098$1.06M0.03%+6,098New
Park Capital Management, LLC5,989$1.04M0.75%+5,989New
Sequoia Financial Advisors, LLC5,940$1.03M0.01%+3,633+157.5%Added
Prudential Financial Inc5,937$1.03M0.00%−5,033−45.9%Reduced
Havemeyer Place LP5,891$1.03M0.20%+5,891New
Groupama Asset Managment5,590$972.9K0.01%−7,585−57.6%Reduced
Mercer Global Advisors Inc5,567$968.8K0.00%+2,045+58.1%Added
Ieq Capital, LLC5,563$968.2K0.00%+5,563New
Commonwealth Equity Services, LLC5,488$955.2K0.00%−45−0.8%Reduced
Captrust Financial Advisors5,384$937.0K0.00%−238−4.2%Reduced
Fulton Bank, N.A.5,325$926.8K0.03%+146+2.8%Added
Tower Research Capital LLC (TRC)5,297$921.9K0.02%+3,955+294.7%Added
E. Ohman J:or Asset Management AB5,239$911.8K0.02%+5,239New
Pinkerton Retirement Specialists, LLC5,148$896.0K0.09%+5,148New
Principal Securities, Inc.5,121$891.3K0.01%−1,883−26.9%Reduced
Moody Aldrich Partners LLC5,036$876.5K0.16%−515−9.3%Reduced
Resources Investment Advisors, LLC.5,032$875.8K0.01%+853+20.4%Added
Vident Advisory, LLC5,014$872.6K0.01%−544−9.8%Reduced
Voleon Capital Management LP4,883$849.8K0.02%−42,784−89.8%Reduced
Meeder Advisory Services, Inc.4,782$832.3K0.04%+570+13.5%Added
Intrust Bank NA4,735$824.1K0.07%−692−12.8%Reduced
B. Metzler seel. Sohn & Co. AG4,733$823.7K0.01%−348−6.8%Reduced
Private Advisor Group, LLC4,667$812.2K0.00%−64−1.4%Reduced
Rice Hall James & Associates, LLC4,536$789.4K0.04%−75,131−94.3%Reduced
Summit Trail Advisors, LLC4,464$776.9K0.01%+2,731+157.6%Added
CWM, LLC4,347$757.0K0.00%+1,892+77.1%Added
Vestcor Inc4,238$738.0K0.02%+4,238New
UniSuper Management Pty Ltd4,200$731.0K0.00%+4,200New
University of Texas/Texas Am Investment Managment Co4,170$725.7K0.10%+4,170New
Edgestream Partners, L.P.4,116$716.3K0.02%+4,116New
Independent Financial Group, LLC4,113$715.8K0.02%+2,578+167.9%Added
MidFirst Bank4,012$698.2K0.06%+4,012New
Ethic Inc.4,001$696.3K0.01%+2,512+168.7%Added
Oxford Asset Management LLP3,931$684.2K0.24%−4,377−52.7%Reduced
Concurrent Investment Advisors, LLC3,930$684.0K0.01%+1,667+73.7%Added
GraniteShares Advisors LLC3,905$679.6K0.41%+3,905New
Prudential PLC3,902$679.1K0.01%+3,902New
Coldstream Capital Management Inc3,848$669.7K0.01%−672−14.9%Reduced
Global Retirement Partners, LLC3,838$668.0K0.01%+1,990+107.7%Added
Envestnet Portfolio Solutions, Inc.3,700$643.9K0.00%−464−11.1%Reduced
Persistent Asset Partners Ltd3,692$642.6K0.31%+3,692New
Acadian Asset Management LLC3,605$626.0K0.00%+1,402+63.6%Added
NewEdge Wealth, LLC3,540$616.1K0.01%+509+16.8%Added
Virtus Investment Advisers, Inc.3,468$603.6K0.16%−1,119−24.4%Reduced
ICICI Prudential Asset Management Co Ltd3,422$595.6K0.07%+3,422New
Tema ETFs LLC3,395$590.9K0.05%−902−21.0%Reduced
Cambridge Investment Research Advisors, Inc.3,391$590.0K0.00%+354+11.7%Added
TCW Group Inc3,285$571.7K0.00%+3,285New
Beacon Financial Advisory LLC3,283$571.4K0.13%−5,197−61.3%Reduced