| Sep 11, 2026 (view filing)4:04 PM ET | Sep 9 | 2 days | Brennan David RDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $124.00 | −$3.10M | −38.9%39.2K after | |
| Aug 19, 2026 (view filing)4:10 PM ET | Aug 17 | 2 days | Sharoky Melvin MDDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $127.53 | −$637.6K | −100.0%0 after | |
| Aug 12, 2026 (view filing)5:04 PM ET | Aug 10 | 2 days | Adsett RogerChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −239.8K | $133.27 | −$32.0M | −70.8%98.7K after | |
| Aug 7, 2026 (view filing)4:39 PM ET | Aug 6 | 1 day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −27.2K | $128.61 | −$3.49M | −31.0%60.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 24, 2026 (view filing)5:02 PM ET | Jul 23 | 1 day | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.7K | $106.06 | −$1.13M | −4.0%259.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 10, 2026 (view filing)4:02 PM ET | Jul 9 | 1 day | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.7K | $117.40 | −$1.26M | −4.0%259.1K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 8, 2026 (view filing)4:03 PM ET | Jul 6 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.3K | $109.98 | −$1.35M | −16.9%60.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 26, 2026 (view filing) | Jun 25 | 1 day | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −21.4K | $103.32 | −$2.21M | −7.6%258.9K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 24, 2026 (view filing) | Jun 22 | 2 days | Smith Michael AlexanderChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.81K | $95.82 | −$173.1K | −4.6%37.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 10, 2026 (view filing) | Jun 8 | 2 days | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.51K | $94.03 | −$612.6K | −2.5%258.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 5, 2026 (view filing) | Jun 3 | 2 days | Smith Michael AlexanderChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.16K | $102.27 | −$220.8K | −5.2%39.5K after | |
| Jun 5, 2026 (view filing) | Jun 3-5 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.42K | $102.90 | −$455.2K | −6.8%60.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 5, 2026 (view filing) | Jun 3 | 2 days | Adsett RogerChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.37K | $102.27 | −$242.4K | −2.3%98.6K after | |
| Jun 5, 2026 (view filing) | Jun 3 | 2 days | Bonstein SaraChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.40K | $102.27 | −$245.9K | −3.4%69.1K after | |
| Jun 5, 2026 (view filing) | Jun 3 | 2 days | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.61K | $102.27 | −$777.8K | −2.8%265.4K after | |
| May 22, 2026 (view filing) | May 22 | Same day | Smith Michael AlexanderChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.15K | $108.47 | −$667.0K | −12.9%41.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 20, 2026 (view filing) | May 18 | 2 days | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.6K | $106.33 | −$2.72M | −8.6%273.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 15, 2026 (view filing) | May 13 | 2 days | Smith Michael AlexanderChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.11K | $116.18 | −$477.4K | −7.9%47.8K after | |
| May 15, 2026 (view filing) | May 13-14 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −18.3K | $116.12 | −$2.13M | −22.0%64.9K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 15, 2026 (view filing) | May 13 | 2 days | Adsett RogerChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.84K | $116.18 | −$678.1K | −5.5%101.0K after | |
| May 15, 2026 (view filing) | May 13 | 2 days | Bonstein SaraChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.27K | $116.18 | −$961.0K | −10.4%71.5K after | |
| May 15, 2026 (view filing) | May 13 | 2 days | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.3K | $116.18 | −$1.54M | −4.4%287.9K after | |
| May 13, 2026 (view filing) | May 11 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.9K | $100.40 | −$1.30M | −13.5%83.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 4 | 2 days | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.7K | $137.34 | −$1.47M | −3.4%301.2K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 17, 2026 (view filing) | Apr 16 | 1 day | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.7K | $143.97 | −$1.54M | −3.4%301.2K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 8, 2026 (view filing) | Apr 6 | 2 days | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.7K | $163.22 | −$1.75M | −3.4%301.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 3, 2026 (view filing) | Apr 1 | 2 days | Adsett RogerChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −88.1K | $164.63 | −$14.5M | −45.2%106.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 31, 2026 (view filing) | Mar 30 | 1 day | Smith Michael AlexanderChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −19.6K | $150.98 | −$2.96M | −27.5%51.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 20, 2026 (view filing) | Mar 19 | 1 day | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.7K | $143.52 | −$1.54M | −3.4%301.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 5, 2026 (view filing) | Mar 5 | Same day | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.7K | $146.03 | −$1.56M | −3.4%301.2K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 25, 2026 (view filing) | Feb 24 | 1 day | Smith Michael AlexanderChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −24.8K | $155.77 | −$3.86M | −32.3%51.9K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 23, 2026 (view filing) | Feb 19 | 4 days | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.7K | $150.97 | −$1.62M | −3.4%301.2K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 11, 2026 (view filing) | Feb 9 | 2 days | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.4K | $147.79 | −$1.98M | −4.3%301.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 6, 2026 (view filing) | Feb 5 | 1 day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −869 | $152.44 | −$132.5K | −1.0%83.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 4, 2026 (view filing) | Feb 3 | 1 day | Smith Michael AlexanderChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −640 | $156.27 | −$100.0K | −1.1%56.4K after | |
| Feb 4, 2026 (view filing) | Feb 2-3 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.78K | $154.70 | −$1.36M | −9.4%84.1K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 4, 2026 (view filing) | Feb 3 | 1 day | Adsett RogerChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −791 | $156.17 | −$123.5K | −0.7%106.8K after | |
| Feb 4, 2026 (view filing) | Feb 3 | 1 day | Bonstein SaraChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −748 | $156.34 | −$116.9K | −0.9%79.8K after | |
| Feb 4, 2026 (view filing) | Feb 3 | 1 day | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.01K | $156.34 | −$470.4K | −1.0%303.9K after | |
| Jan 22, 2026 (view filing) | Jan 20 | 2 days | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.7K | $158.93 | −$1.70M | −3.4%306.9K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 13, 2026 (view filing) | Jan 9 | 4 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.89K | $186.19 | −$351.3K | −2.2%84.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 13, 2026 (view filing) | Jan 12 | 1 day | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −19.2K | $169.00 | −$3.25M | −5.9%306.9K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 8, 2026 (view filing) | Jan 6-8 | 2 days | Smith Michael AlexanderChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.16K | $174.00 | −$549.5K | −5.2%57.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 8, 2026 (view filing) | Jan 6-8 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.5K | $174.06 | −$2.88M | −16.0%86.8K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 8, 2026 (view filing) | Jan 6-8 | 2 days | Adsett RogerChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.29K | $174.06 | −$746.7K | −3.8%107.6K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 8, 2026 (view filing) | Jan 6-8 | 2 days | Bonstein SaraChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.64K | $174.22 | −$808.7K | −5.5%80.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 8, 2026 (view filing) | Jan 6-8 | 2 days | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.68K | $174.03 | −$1.68M | −3.0%315.4K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 6, 2026 (view filing) | Jan 5 | 1 day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.3K | $171.38 | −$2.11M | −11.5%94.8K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 6, 2026 (view filing) | Jan 2 | 4 days | Schaeffer Orlov S NicoleChief People Strategy Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −87.3K | $175.20 | −$15.3M | −67.6%41.8K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 19, 2025 (view filing) | Dec 18 | 1 day | Lewis WilliamChair and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.7K | $166.97 | −$1.79M | −3.4%303.9K after | 10 lotsThis row combines 10 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
