| Aug 7, 2026 (view filing)4:39 PM ET | Aug 6 | 1 day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −27.2K | $128.61 | −$3.49M | −31.0%60.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 8, 2026 (view filing)4:03 PM ET | Jul 6 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.3K | $109.98 | −$1.35M | −16.9%60.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 5, 2026 (view filing) | Jun 3-5 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.42K | $102.90 | −$455.2K | −6.8%60.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 15, 2026 (view filing) | May 13-14 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −18.3K | $116.12 | −$2.13M | −22.0%64.9K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 13, 2026 (view filing) | May 11 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.9K | $100.40 | −$1.30M | −13.5%83.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 6, 2026 (view filing) | Feb 5 | 1 day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −869 | $152.44 | −$132.5K | −1.0%83.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 4, 2026 (view filing) | Feb 2-3 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.78K | $154.70 | −$1.36M | −9.4%84.1K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 13, 2026 (view filing) | Jan 9 | 4 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.89K | $186.19 | −$351.3K | −2.2%84.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 8, 2026 (view filing) | Jan 6-8 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.5K | $174.06 | −$2.88M | −16.0%86.8K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 6, 2026 (view filing) | Jan 5 | 1 day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.3K | $171.38 | −$2.11M | −11.5%94.8K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 3, 2025 (view filing) | Dec 1 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.89K | $206.98 | −$1.84M | −9.7%83.1K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 13, 2025 (view filing) | Nov 11 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −31.2K | $189.68 | −$5.92M | −27.3%83.1K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 4, 2025 (view filing) | Sep 2 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −186.6K | $144.34 | −$26.9M | −69.2%83.1K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 6, 2025 (view filing) | Aug 4 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.71K | $109.50 | −$954.3K | −9.5%83.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 12, 2025 (view filing) | Jun 10-11 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −45.2K | $91.16 | −$4.12M | −35.2%83.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 4, 2025 (view filing) | Jun 3 | 1 day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.69K | $71.50 | −$120.5K | −2.0%83.1K after | |
| May 19, 2025 (view filing) | May 15-16 | 4 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.7K | $65.79 | −$771.3K | −12.1%84.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 15, 2025 (view filing) | May 13-14 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.2K | $67.43 | −$684.6K | −10.1%90.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 12, 2025 (view filing) | Feb 10 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −37.8K | $78.61 | −$2.97M | −27.4%100.2K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 7, 2025 (view filing) | Feb 6-7 | 1 day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −33.1K | $80.90 | −$2.68M | −19.4%138.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 16, 2025 (view filing) | Jan 14 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.38K | $68.72 | −$95.1K | −1.4%100.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 10, 2025 (view filing) | Jan 7-10 | 3 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.2K | $64.70 | −$725.8K | −9.9%101.5K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 16, 2024 (view filing) | Sep 12-16 | 4 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −41.0K | $74.91 | −$3.07M | −27.9%106.1K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 10, 2024 (view filing) | Sep 6 | 4 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −149.0K | $71.23 | −$10.6M | −58.4%106.1K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 12, 2024 (view filing) | Jun 10 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −21.2K | $60.00 | −$1.27M | −16.6%106.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 30, 2024 (view filing) | May 28-30 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −125.0K | $50.53 | −$6.32M | −54.1%106.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 17, 2024 (view filing) | May 17 | Same day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.64K | $25.09 | −$116.5K | −4.2%106.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 15, 2024 (view filing) | May 14 | 1 day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.6K | $25.47 | −$271.0K | −8.8%110.8K after | |
| Jan 12, 2024 (view filing) | Jan 12 | Same day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.67K | $28.63 | −$133.6K | −4.2%106.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 11, 2024 (view filing) | Jan 9-10 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.96K | $28.99 | −$172.8K | −5.1%111.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 5, 2024 (view filing) | Jan 5 | Same day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.39K | $29.21 | −$40.5K | −1.2%117.5K after | |
| Dec 22, 2023 (view filing) | Dec 22 | Same day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −28.3K | $30.00 | −$849.3K | −21.1%106.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 15, 2023 (view filing) | Jun 13 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.87K | $19.27 | −$170.9K | −7.7%106.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 17, 2023 (view filing) | May 15-16 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.29K | $18.94 | −$81.3K | −3.6%114.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 12, 2023 (view filing) | Jan 10 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.44K | $18.06 | −$62.1K | −4.5%72.8K after | |
| Jan 6, 2023 (view filing) | Jan 5 | 1 day | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.37K | $19.73 | −$27.1K | −2.1%65.1K after | |
| May 18, 2022 (view filing) | May 16 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.57K | $18.51 | −$29.1K | −2.3%66.4K after | |
| Jan 13, 2022 (view filing) | Jan 11 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.50K | $25.11 | −$37.5K | −3.1%46.0K after | |
| Jan 7, 2022 (view filing) | Jan 5 | 2 days | Flammer Martina M.D.Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.42K | $27.61 | −$39.3K | −4.1%33.3K after | |
