INSMED Inc
INSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001104506
In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q3 2025
Institutional positions in INSMED Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 566
- +59 vs. Q2 2025
- Shares held
- 210.9M
- +2.45M (+1.2%) vs. Q2 2025
- Total value
- $30.3B
- +$9.37B (+44.7%) vs. Q2 2025
- New holders
- 130
- 194 more added
- Sold out
- 71
- 197 more reduced
9 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 667 | $23.8B |
| Q1 2026 | 675 | $35.7B |
| Q4 2025 | 678 | $37.8B |
| Q3 2025 | 566 | $30.3B |
| Q2 2025 | 516 | $21.2B |
| Q1 2025 | 442 | $15.3B |
| Q4 2024 | 439 | $13.3B |
| Q3 2024 | 414 | $13.7B |
| Q2 2024 | 378 | $11.7B |
| Q1 2024 | 288 | $4.07B |
| Q4 2023 | 271 | $4.64B |
| Q3 2023 | 252 | $3.72B |
| Q2 2023 | 223 | $3.09B |
| Q1 2023 | 230 | $2.48B |
| Q4 2022 | 225 | $2.87B |
| Q3 2022 | 238 | $2.74B |
| Q2 2022 | 214 | $2.55B |
| Q1 2022 | 224 | $2.97B |
| Q4 2021 | 214 | $3.36B |
| Q3 2021 | 193 | $3.40B |
| Q2 2021 | 203 | $3.46B |
| Q1 2021 | 199 | $3.63B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| JPMorgan Chase & Co | 23,047,676 | $3.32B | 0.21% | +7,411,277+47.4% | Added |
| Darwin Global Management, Ltd. | 20,457,445 | $2.90B | 80.54% | +1,112,824+5.8% | Added |
| Vanguard Group Inc | 19,935,820 | $2.87B | 0.04% | +2,291,328+13.0% | Added |
| BlackRock, Inc. | 12,364,904 | $1.78B | 0.03% | +1,222,472+11.0% | Added |
| FMR LLC | 9,180,963 | $1.32B | 0.07% | +4,087,702+80.3% | Added |
| Capital International Investors | 7,553,853 | $1.09B | 0.18% | +74,994+1.0% | Added |
| Price T Rowe Associates Inc | 6,931,466 | $998.2M | 0.11% | −4,299,239−38.3% | Reduced |
| Baker Bros. Advisors LP | 6,703,484 | $965.4M | 6.98% | −1,009,416−13.1% | Reduced |
| D. E. Shaw & Co., Inc. | 5,657,464 | $814.7M | 0.66% | +2,234,845+65.3% | Added |
| Artisan Partners Limited Partnership | 4,937,683 | $711.1M | 1.02% | +1,623,342+49.0% | Added |
| State Street Corp | 3,984,354 | $573.8M | 0.02% | −293,534−6.9% | Reduced |
| Geode Capital Management, LLC | 3,759,427 | $541.5M | 0.03% | +418,720+12.5% | Added |
| Orbis Allan Gray Ltd | 3,250,868 | $468.2M | 2.01% | +1,726,734+113.3% | Added |
| RTW Investments, LP | 3,084,558 | $444.2M | 5.47% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 2,721,879 | $392.0M | 0.09% | −236,094−8.0% | Reduced |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 2,423,435 | $349.0M | 8.88% | +170,000+7.5% | Added |
| Millennium Management LLC | 2,336,112 | $336.4M | 0.26% | +214,395+10.1% | Added |
| Franklin Resources Inc | 2,139,725 | $308.1M | 0.08% | −210,408−9.0% | Reduced |
| Citadel Advisors LLC | 2,057,641 | $296.3M | 0.24% | +524,364+34.2% | Added |
| Invesco Ltd. | 2,003,871 | $288.6M | 0.05% | +107,538+5.7% | Added |
| UBS Group AG | 1,646,239 | $237.1M | 0.05% | +1,352,785+461.0% | Added |
| Bank of America Corp | 1,601,806 | $230.7M | 0.02% | +375,069+30.6% | Added |
| Integral Health Asset Management, LLC | 1,600,000 | $230.4M | 16.80% | 00.0% | Unchanged |
| William Blair Investment Management, LLC | 1,555,057 | $223.9M | 0.58% | −110,545−6.6% | Reduced |
| Qube Research & Technologies Ltd | 1,544,315 | $222.4M | 0.31% | +462,265+42.7% | Added |
| Lord, Abbett & Co. LLC | 1,444,656 | $208.0M | 0.62% | −101,203−6.5% | Reduced |
| Royal Bank of Canada | 1,355,331 | $195.2M | 0.03% | +927,530+216.8% | Added |
| Adage Capital Partners GP, L.L.C. | 1,252,503 | $180.4M | 0.29% | −1,606,949−56.2% | Reduced |
| Janus Henderson Group PLC | 1,202,783 | $173.2M | 0.08% | −1,090,359−47.5% | Reduced |
| Bank of New York Mellon Corp | 1,138,901 | $164.0M | 0.03% | −58,572−4.9% | Reduced |
| Pictet Asset Management Holding SA | 1,140,827 | $163.9M | 0.16% | −412,801−26.6% | Reduced |
| Castle Hook Partners LP | 1,091,405 | $157.2M | 2.38% | +638,749+141.1% | Added |
| Holocene Advisors, LP | 1,083,681 | $156.1M | 0.36% | −933,125−46.3% | Reduced |
| Northern Trust Corp | 1,072,942 | $154.5M | 0.02% | +103,142+10.6% | Added |
| Clearbridge Investments, LLC | 1,068,018 | $153.8M | 0.12% | −356,544−25.0% | Reduced |
| Summit Partners Public Asset Management, LLC | 1,041,845 | $150.0M | 4.89% | +32,908+3.3% | Added |
| Nwi Management LP | 1,021,000 | $147.0M | 14.52% | +301,000+41.8% | Added |
| Eventide Asset Management, LLC | 1,005,107 | $144.7M | 2.38% | −191,387−16.0% | Reduced |
| Charles Schwab Investment Management Inc | 975,279 | $140.4M | 0.02% | −324,289−25.0% | Reduced |
| Morgan Stanley | 963,631 | $138.8M | 0.01% | −80,160−7.7% | Reduced |
| Hood River Capital Management LLC | 881,403 | $126.9M | 1.50% | −18,200−2.0% | Reduced |
| Alliancebernstein L.P. | 868,772 | $125.1M | 0.04% | −474,440−35.3% | Reduced |
| Principal Financial Group Inc | 864,294 | $124.5M | 0.06% | −483,733−35.9% | Reduced |
| FIL Ltd | 851,954 | $122.7M | 0.10% | −313,510−26.9% | Reduced |
| Goldman Sachs Group Inc | 829,317 | $119.4M | 0.02% | −981,578−54.2% | Reduced |
| Fiera Capital Corp | 809,121 | $116.5M | 0.38% | +61,084+8.2% | Added |
| Jane Street Group, LLC | 791,734 | $114.0M | 0.13% | −561,188−41.5% | Reduced |
| Two Sigma Investments, LP | 772,780 | $111.3M | 0.17% | +396,272+105.2% | Added |
| Raymond James Financial Inc | 759,978 | $109.4M | 0.04% | −24,573−3.1% | Reduced |
| Artia Global Partners LP | 732,212 | $105.4M | 18.55% | −20,500−2.7% | Reduced |
| Wellington Management Group LLP | 718,043 | $103.4M | 0.02% | −441,656−38.1% | Reduced |
| Perceptive Advisors LLC | 702,130 | $101.1M | 2.92% | +51,878+8.0% | Added |
| Marshall Wace, LLP | 658,647 | $94.9M | 0.10% | −454,714−40.8% | Reduced |
| Maverick Capital LtdSuperinvestorMaverick Capital | 656,539 | $94.5M | 1.27% | −147,594−18.4% | Reduced |
| Macquarie Group Ltd | 649,847 | $93.6M | 0.11% | −481,076−42.5% | Reduced |
| Ensign Peak Advisors, Inc | 642,034 | $92.5M | 0.15% | +77,645+13.8% | Added |
| Jennison Associates LLC | 602,775 | $86.8M | 0.05% | −112,831−15.8% | Reduced |
| GW&K Investment Management, LLC | 601,803 | $86.7M | 0.77% | −672,513−52.8% | Reduced |
| SEI Investments Co | 593,885 | $85.5M | 0.09% | +160,257+37.0% | Added |
| Nuveen, LLC | 588,122 | $84.7M | 0.02% | −865−0.1% | Reduced |
| 1832 Asset Management L.P. | 584,800 | $84.2M | 0.14% | +584,800 | New |
| Wells Fargo & Company | 513,849 | $74.0M | 0.02% | +254,642+98.2% | Added |
| UBS Asset Management Americas Inc | 512,749 | $73.8M | 0.02% | −183,212−26.3% | Reduced |
| Bank of Nova Scotia | 506,245 | $72.9M | 0.13% | +506,245 | New |
| Alkeon Capital Management LLC | 500,000 | $72.0M | 0.33% | 00.0% | Unchanged |
| Loomis Sayles & Co L P | 492,296 | $70.9M | 0.08% | −301,273−38.0% | Reduced |
| Palo Alto Investors LP | 491,805 | $70.8M | 13.11% | −373,308−43.2% | Reduced |
| Westfield Capital Management Co LP | 487,927 | $70.3M | 0.29% | −851,361−63.6% | Reduced |
| Voloridge Investment Management, LLC | 471,649 | $67.9M | 0.23% | +158,596+50.7% | Added |
| Deerfield Management Company, L.P. (Series C) | 471,000 | $67.8M | 1.04% | −229,700−32.8% | Reduced |
| Point72 Asset Management, L.P. | 464,217 | $66.9M | 0.15% | −26,450−5.4% | Reduced |
| Affinity Asset Advisors, LLC | 450,000 | $64.8M | 6.03% | −25,000−5.3% | Reduced |
| New York State Common Retirement Fund | 445,876 | $64.2M | 0.08% | +18,123+4.2% | Added |
| BNP Paribas Arbitrage, SA | 433,340 | $62.4M | 0.05% | −320,820−42.5% | Reduced |
| Cormorant Asset Management, LP | 430,000 | $61.9M | 4.27% | −110,000−20.4% | Reduced |
| TimesSquare Capital Management, LLC | 425,085 | $61.2M | 0.88% | −448,406−51.3% | Reduced |
| TD Asset Management Inc | 398,256 | $57.4M | 0.05% | +3,062+0.8% | Added |
| Candriam Luxembourg S.C.A. | 397,588 | $57.3M | 0.30% | −41,100−9.4% | Reduced |
| Dimensional Fund Advisors LP | 386,671 | $55.7M | 0.01% | −25,073−6.1% | Reduced |
| Rock Springs Capital Management LP | 385,000 | $55.4M | 3.24% | −140,000−26.7% | Reduced |
| ING Groep NV | 373,500 | $53.8M | 0.29% | +373,500 | New |
| Polar Capital Holdings Plc | 371,887 | $53.6M | 0.26% | −326,073−46.7% | Reduced |
| Swiss National Bank | 371,300 | $53.5M | 0.03% | +23,900+6.9% | Added |
| Victory Capital Management Inc | 354,907 | $51.1M | 0.03% | +172,134+94.2% | Added |
| Renaissance Technologies LLC | 352,887 | $50.8M | 0.07% | +44,200+14.3% | Added |
| Amundi | 317,096 | $50.2M | 0.02% | +305,597+2,657.6% | Added |
| Envestnet Asset Management Inc | 342,785 | $49.4M | 0.01% | −23,042−6.3% | Reduced |
| Long Focus Capital Management, LLC | 338,000 | $48.7M | 2.78% | −182,200−35.0% | Reduced |
| Frontier Capital Management Co LLC | 328,884 | $47.4M | 0.42% | +181,083+122.5% | Added |
| Federated Hermes, Inc. | 328,223 | $47.3M | 0.08% | +219,838+202.8% | Added |
| Patient Square Capital LP | 326,400 | $47.0M | 12.57% | −32,400−9.0% | Reduced |
| First Turn Management, LLC | 319,773 | $46.1M | 6.91% | −52,899−14.2% | Reduced |
| California Public Employees Retirement System | 310,886 | $44.8M | 0.03% | +88,650+39.9% | Added |
| Brevan Howard Capital Management LP | 294,047 | $42.3M | 0.61% | +91,453+45.1% | Added |
| Samlyn Capital, LLC | 292,643 | $42.1M | 0.60% | +292,643 | New |
| AQR Capital Management LLC | 287,286 | $40.9M | 0.03% | +237,571+477.9% | Added |
| Eagle Health Investments LP | 271,600 | $39.1M | 10.27% | −157,000−36.6% | Reduced |
| First Trust Advisors LP | 240,646 | $34.7M | 0.03% | +193,254+407.8% | Added |
| Standard Life Aberdeen plc | 234,622 | $33.8M | 0.05% | −75,127−24.3% | Reduced |
| Susquehanna International Group, LLP | 233,106 | $33.6M | 0.05% | +20,884+9.8% | Added |