INSMED Inc
INSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001104506
In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in INSMED Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 678
- +121 vs. Q3 2025
- Shares held
- 217.4M
- +6.76M (+3.2%) vs. Q3 2025
- Total value
- $37.8B
- +$7.55B (+24.9%) vs. Q3 2025
- New holders
- 202
- 241 more added
- Sold out
- 81
- 180 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 667 | $23.8B |
| Q1 2026 | 675 | $35.7B |
| Q4 2025 | 678 | $37.8B |
| Q3 2025 | 566 | $30.3B |
| Q2 2025 | 516 | $21.2B |
| Q1 2025 | 442 | $15.3B |
| Q4 2024 | 439 | $13.3B |
| Q3 2024 | 414 | $13.7B |
| Q2 2024 | 378 | $11.7B |
| Q1 2024 | 288 | $4.07B |
| Q4 2023 | 271 | $4.64B |
| Q3 2023 | 252 | $3.72B |
| Q2 2023 | 223 | $3.09B |
| Q1 2023 | 230 | $2.48B |
| Q4 2022 | 225 | $2.87B |
| Q3 2022 | 238 | $2.74B |
| Q2 2022 | 214 | $2.55B |
| Q1 2022 | 224 | $2.97B |
| Q4 2021 | 214 | $3.36B |
| Q3 2021 | 193 | $3.40B |
| Q2 2021 | 203 | $3.46B |
| Q1 2021 | 199 | $3.63B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| JPMorgan Chase & Co | 23,199,512 | $4.04B | 0.27% | +151,836+0.7% | Added |
| Vanguard Group Inc | 21,076,344 | $3.67B | 0.05% | +1,140,524+5.7% | Added |
| Darwin Global Management, Ltd. | 20,933,277 | $3.64B | 73.78% | +475,832+2.3% | Added |
| BlackRock, Inc. | 15,065,052 | $2.62B | 0.04% | +2,700,148+21.8% | Added |
| FMR LLC | 9,927,936 | $1.73B | 0.09% | +746,973+8.1% | Added |
| Invesco Ltd. | 7,518,338 | $1.31B | 0.12% | +5,514,467+275.2% | Added |
| Baker Bros. Advisors LP | 6,592,746 | $1.15B | 6.72% | −110,738−1.7% | Reduced |
| State Street Corp | 5,201,744 | $905.3M | 0.03% | +1,217,390+30.6% | Added |
| Capital International Investors | 5,151,671 | $896.6M | 0.14% | −2,402,182−31.8% | Reduced |
| Artisan Partners Limited Partnership | 4,843,749 | $843.0M | 1.29% | −93,934−1.9% | Reduced |
| RTW Investments, LP | 4,842,879 | $842.9M | 8.44% | +1,758,321+57.0% | Added |
| D. E. Shaw & Co., Inc. | 4,350,995 | $757.2M | 0.58% | −1,306,469−23.1% | Reduced |
| Geode Capital Management, LLC | 4,299,052 | $751.9M | 0.05% | +539,625+14.4% | Added |
| Orbis Allan Gray Ltd | 4,179,957 | $727.5M | 3.05% | +929,089+28.6% | Added |
| Price T Rowe Associates Inc | 4,039,466 | $703.0M | 0.08% | −2,892,000−41.7% | Reduced |
| Norges Bank | 2,910,971 | $506.6M | 0.05% | +2,910,971 | New |
| Franklin Resources Inc | 2,755,536 | $479.6M | 0.12% | +615,811+28.8% | Added |
| Ameriprise Financial Inc | 1,968,857 | $342.7M | 0.08% | −753,022−27.7% | Reduced |
| UBS Group AG | 1,867,635 | $325.0M | 0.06% | +221,396+13.4% | Added |
| Bank of America Corp | 1,725,681 | $300.3M | 0.02% | +123,875+7.7% | Added |
| Morgan Stanley | 1,631,906 | $284.0M | 0.02% | +668,275+69.3% | Added |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 1,481,752 | $257.9M | 6.11% | −941,683−38.9% | Reduced |
| Bank of New York Mellon Corp | 1,390,042 | $241.9M | 0.04% | +251,141+22.1% | Added |
| Millennium Management LLC | 1,311,654 | $228.3M | 0.16% | −1,024,458−43.9% | Reduced |
| Castle Hook Partners LP | 1,253,568 | $218.2M | 3.14% | +162,163+14.9% | Added |
| Integral Health Asset Management, LLC | 1,250,000 | $217.6M | 11.03% | −350,000−21.9% | Reduced |
| Goldman Sachs Group Inc | 1,244,913 | $216.7M | 0.03% | +415,596+50.1% | Added |
| Northern Trust Corp | 1,238,438 | $215.5M | 0.03% | +165,496+15.4% | Added |
| William Blair Investment Management, LLC | 1,221,096 | $212.5M | 0.59% | −333,961−21.5% | Reduced |
| Nomura Asset Management International Inc. | 1,183,029 | $205.9M | 0.31% | +1,183,029 | New |
| Citadel Advisors LLC | 1,157,295 | $201.4M | 0.14% | −900,346−43.8% | Reduced |
| Charles Schwab Investment Management Inc | 1,027,355 | $178.8M | 0.03% | +52,076+5.3% | Added |
| Fiera Capital Corp | 992,892 | $172.8M | 0.55% | +183,771+22.7% | Added |
| Nwi Management LP | 988,460 | $172.0M | 10.51% | −32,540−3.2% | Reduced |
| Two Sigma Investments, LP | 962,156 | $167.5M | 0.25% | +189,376+24.5% | Added |
| Pictet Asset Management Holding SA | 958,963 | $167.3M | 0.16% | −181,864−15.9% | Reduced |
| UBS Asset Management Americas Inc | 943,306 | $164.2M | 0.03% | +430,557+84.0% | Added |
| Jefferies Financial Group Inc. | 926,339 | $161.2M | 1.32% | +818,242+757.0% | Added |
| Amundi | 916,998 | $159.6M | 0.04% | +599,902+189.2% | Added |
| BNP Paribas Arbitrage, SA | 915,419 | $159.3M | 0.10% | +482,079+111.2% | Added |
| Summit Partners Public Asset Management, LLC | 909,080 | $158.2M | 4.45% | −132,765−12.7% | Reduced |
| SEI Investments Co | 890,170 | $154.9M | 0.15% | +296,285+49.9% | Added |
| FIL Ltd | 838,509 | $145.9M | 0.11% | −13,445−1.6% | Reduced |
| Clearbridge Investments, LLC | 819,011 | $142.5M | 0.11% | −249,007−23.3% | Reduced |
| Holocene Advisors, LP | 801,165 | $139.4M | 0.29% | −282,516−26.1% | Reduced |
| Janus Henderson Group PLC | 800,555 | $139.3M | 0.06% | −402,228−33.4% | Reduced |
| Raymond James Financial Inc | 779,254 | $135.6M | 0.04% | +19,276+2.5% | Added |
| Principal Financial Group Inc | 771,358 | $134.2M | 0.07% | −92,936−10.8% | Reduced |
| Lord, Abbett & Co. LLC | 720,898 | $125.5M | 0.38% | −723,758−50.1% | Reduced |
| Artia Global Partners LP | 682,212 | $118.7M | 19.08% | −50,000−6.8% | Reduced |
| Nuveen, LLC | 650,404 | $113.2M | 0.03% | +62,282+10.6% | Added |
| Victory Capital Management Inc | 646,714 | $112.6M | 0.06% | +291,807+82.2% | Added |
| Alliancebernstein L.P. | 642,719 | $111.9M | 0.04% | −226,053−26.0% | Reduced |
| Hood River Capital Management LLC | 637,577 | $111.0M | 1.22% | −243,826−27.7% | Reduced |
| Federated Hermes, Inc. | 632,298 | $110.0M | 0.18% | +304,075+92.6% | Added |
| Deutsche Bank AG | 590,030 | $102.7M | 0.03% | +385,676+188.7% | Added |
| Wells Fargo & Company | 586,651 | $102.1M | 0.02% | +72,802+14.2% | Added |
| Swiss National Bank | 579,112 | $100.8M | 0.06% | +207,812+56.0% | Added |
| Jennison Associates LLC | 562,296 | $97.9M | 0.06% | −40,479−6.7% | Reduced |
| Legal & General Group Plc | 540,313 | $94.0M | 0.02% | +332,292+159.7% | Added |
| Royal Bank of Canada | 506,811 | $88.2M | 0.02% | −848,520−62.6% | Reduced |
| Nearwater Capital Markets, Ltd | 500,000 | $87.0M | 1.49% | +300,000+150.0% | Added |
| TimesSquare Capital Management, LLC | 490,506 | $85.4M | 1.29% | +65,421+15.4% | Added |
| Palo Alto Investors LP | 489,482 | $85.2M | 11.86% | −2,323−0.5% | Reduced |
| Wellington Management Group LLP | 486,138 | $84.6M | 0.01% | −231,905−32.3% | Reduced |
| Eventide Asset Management, LLC | 483,589 | $84.2M | 1.31% | −521,518−51.9% | Reduced |
| GW&K Investment Management, LLC | 482,670 | $84.0M | 0.73% | −119,133−19.8% | Reduced |
| AQR Capital Management LLC | 468,260 | $81.5M | 0.04% | +180,974+63.0% | Added |
| Affinity Asset Advisors, LLC | 450,000 | $78.3M | 5.63% | 00.0% | Unchanged |
| Barclays PLC | 444,706 | $77.4M | 0.03% | +330,510+289.4% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 435,442 | $75.8M | 0.04% | +435,442 | New |
| Westfield Capital Management Co LP | 432,521 | $75.3M | 0.31% | −55,406−11.4% | Reduced |
| Candriam Luxembourg S.C.A. | 401,042 | $69.8M | 0.35% | +3,454+0.9% | Added |
| Dimensional Fund Advisors LP | 399,073 | $69.5M | 0.01% | +12,402+3.2% | Added |
| Two Sigma Advisers, LP | 395,000 | $68.7M | 0.13% | +343,700+670.0% | Added |
| Marshall Wace, LLP | 389,881 | $67.9M | 0.07% | −268,766−40.8% | Reduced |
| Ensign Peak Advisors, Inc | 382,202 | $66.5M | 0.12% | −259,832−40.5% | Reduced |
| Balyasny Asset Management LLC | 380,561 | $66.2M | 0.12% | +343,080+915.3% | Added |
| Samlyn Capital, LLC | 369,575 | $64.3M | 1.03% | +76,932+26.3% | Added |
| Gateway Investment Advisers LLC | 365,000 | $63.5M | 0.59% | +365,000 | New |
| California Public Employees Retirement System | 354,909 | $61.8M | 0.04% | +44,023+14.2% | Added |
| Polar Capital Holdings Plc | 344,228 | $59.9M | 0.27% | −27,659−7.4% | Reduced |
| ProShare Advisors LLC | 340,740 | $59.3M | 0.10% | +333,210+4,425.1% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 328,328 | $57.2M | 0.07% | +129,626+65.2% | Added |
| Rock Springs Capital Management LP | 319,250 | $55.6M | 2.85% | −65,750−17.1% | Reduced |
| California State Teachers Retirement System | 310,330 | $54.0M | 0.05% | +130,928+73.0% | Added |
| Adage Capital Partners GP, L.L.C. | 300,000 | $52.2M | 0.08% | −952,503−76.0% | Reduced |
| Frontier Capital Management Co LLC | 284,844 | $49.6M | 0.53% | −44,040−13.4% | Reduced |
| Zurich Insurance Group Ltd | 281,098 | $48.9M | 0.34% | +281,098 | New |
| National Pension Service | 280,442 | $48.8M | 0.04% | +280,442 | New |
| New York State Common Retirement Fund | 276,284 | $48.1M | 0.06% | −169,592−38.0% | Reduced |
| Envestnet Asset Management Inc | 276,105 | $48.1M | 0.01% | −66,680−19.5% | Reduced |
| Cormorant Asset Management, LP | 275,000 | $47.9M | 2.71% | −155,000−36.0% | Reduced |
| Rhumbline Advisers | 268,326 | $46.7M | 0.04% | +55,423+26.0% | Added |
| Patient Square Capital LP | 267,000 | $46.5M | 9.95% | −59,400−18.2% | Reduced |
| First Turn Management, LLC | 264,293 | $46.0M | 5.26% | −55,480−17.3% | Reduced |
| TD Asset Management Inc | 262,478 | $45.7M | 0.04% | −135,778−34.1% | Reduced |
| Axiom Investors LLC | 255,849 | $44.5M | 0.39% | +148,116+137.5% | Added |
| Standard Life Aberdeen plc | 253,112 | $44.1M | 0.07% | +18,490+7.9% | Added |
| First Trust Advisors LP | 247,940 | $43.2M | 0.03% | +7,294+3.0% | Added |