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INSMED Inc

INSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001104506

In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q2 2025

Institutional positions in INSMED Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
516
+78 vs. Q1 2025
Shares held
210.4M
+10.8M (+5.4%) vs. Q1 2025
Total value
$21.2B
+$5.90B (+38.7%) vs. Q1 2025
New holders
130
166 more added
Sold out
52
188 more reduced

4 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 516 institutions
Q1 2021: 199 institutionsQ2 2021: 203 institutionsQ3 2021: 193 institutionsQ4 2021: 214 institutionsQ1 2022: 224 institutionsQ2 2022: 214 institutionsQ3 2022: 238 institutionsQ4 2022: 225 institutionsQ1 2023: 230 institutionsQ2 2023: 223 institutionsQ3 2023: 252 institutionsQ4 2023: 271 institutionsQ1 2024: 288 institutionsQ2 2024: 378 institutionsQ3 2024: 414 institutionsQ4 2024: 439 institutionsQ1 2025: 442 institutionsQ2 2025: 516 institutionsQ3 2025: 566 institutionsQ4 2025: 678 institutionsQ1 2026: 675 institutionsQ2 2026: 667 institutions
Value heldQ2 2025: $21.2B
Q1 2021: $3.63BQ2 2021: $3.46BQ3 2021: $3.40BQ4 2021: $3.36BQ1 2022: $2.97BQ2 2022: $2.55BQ3 2022: $2.74BQ4 2022: $2.87BQ1 2023: $2.48BQ2 2023: $3.09BQ3 2023: $3.72BQ4 2023: $4.64BQ1 2024: $4.07BQ2 2024: $11.7BQ3 2024: $13.7BQ4 2024: $13.3BQ1 2025: $15.3BQ2 2025: $21.2BQ3 2025: $30.3BQ4 2025: $37.8BQ1 2026: $35.7BQ2 2026: $23.8B
Institutions holding INSM and their total value by quarter
QuarterHoldersValue
Q2 2026667$23.8B
Q1 2026675$35.7B
Q4 2025678$37.8B
Q3 2025566$30.3B
Q2 2025516$21.2B
Q1 2025442$15.3B
Q4 2024439$13.3B
Q3 2024414$13.7B
Q2 2024378$11.7B
Q1 2024288$4.07B
Q4 2023271$4.64B
Q3 2023252$3.72B
Q2 2023223$3.09B
Q1 2023230$2.48B
Q4 2022225$2.87B
Q3 2022238$2.74B
Q2 2022214$2.55B
Q1 2022224$2.97B
Q4 2021214$3.36B
Q3 2021193$3.40B
Q2 2021203$3.46B
Q1 2021199$3.63B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q1 2025.

Institutions holding INSM in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Darwin Global Management, Ltd.19,344,621$1.92B80.75%+3,946,646+25.6%Added
Vanguard Group Inc17,644,492$1.78B0.03%−623,630−3.4%Reduced
JPMorgan Chase & Co15,636,399$1.57B0.11%+9,282,377+146.1%Added
Price T Rowe Associates Inc11,230,705$1.13B0.13%−1,692,836−13.1%Reduced
BlackRock, Inc.11,142,432$1.12B0.02%−4,906,450−30.6%Reduced
Baker Bros. Advisors LP7,712,900$776.2M7.53%+2,332,274+43.3%Added
Capital International Investors7,478,859$752.7M0.13%+280,374+3.9%Added
FMR LLC5,093,261$512.6M0.03%+1,698,877+50.0%Added
State Street Corp4,277,888$430.5M0.02%−1,469,405−25.6%Reduced
D. E. Shaw & Co., Inc.3,422,619$344.5M0.34%+2,687,739+365.7%Added
Geode Capital Management, LLC3,340,707$336.3M0.02%−948,028−22.1%Reduced
Artisan Partners Limited Partnership3,314,341$333.6M0.50%+97,073+3.0%Added
RTW Investments, LP3,084,558$310.4M4.42%+70,000+2.3%Added
Ameriprise Financial Inc2,957,973$297.7M0.07%+6,351+0.2%Added
Adage Capital Partners GP, L.L.C.2,859,452$287.8M0.48%−587,492−17.0%Reduced
Franklin Resources Inc2,350,133$236.5M0.06%+201,849+9.4%Added
Janus Henderson Group PLC2,293,142$230.8M0.11%+747,723+48.4%Added
Duquesne Family Office LLCSuperinvestorDuquesne Family Office2,253,435$226.8M5.79%+884,385+64.6%Added
Millennium Management LLC2,121,717$213.5M0.19%+1,442,526+212.4%Added
Holocene Advisors, LP2,016,806$203.0M0.50%−9,616−0.5%Reduced
Norges Bank1,934,899$194.7M0.02%+192,056+11.0%Added
Invesco Ltd.1,896,333$190.8M0.03%+105,009+5.9%Added
Goldman Sachs Group Inc1,810,895$182.2M0.03%+408,274+29.1%Added
Deep Track Capital, LP1,750,000$176.1M5.66%+1,495,249+586.9%Added
William Blair Investment Management, LLC1,665,602$167.6M0.44%−647,615−28.0%Reduced
Integral Health Asset Management, LLC1,600,000$161.0M15.04%+50,000+3.2%Added
Pictet Asset Management Holding SA1,553,628$156.2M0.16%−459,701−22.8%Reduced
Lord, Abbett & Co. LLC1,545,859$155.6M0.50%+195,272+14.5%Added
Citadel Advisors LLC1,533,277$154.3M0.13%+1,158,462+309.1%Added
Orbis Allan Gray Ltd1,524,134$153.4M0.75%+1,524,134New
Clearbridge Investments, LLC1,424,562$143.4M0.12%−404,166−22.1%Reduced
Jane Street Group, LLC1,352,922$136.2M0.22%+1,228,335+985.9%Added
Principal Financial Group Inc1,348,027$135.7M0.07%−407,346−23.2%Reduced
Alliancebernstein L.P.1,343,212$135.2M0.04%−1,080,301−44.6%Reduced
Westfield Capital Management Co LP1,339,288$134.8M0.57%−67,321−4.8%Reduced
Charles Schwab Investment Management Inc1,299,568$130.8M0.02%−303,087−18.9%Reduced
GW&K Investment Management, LLC1,274,316$128.2M1.15%−103,410−7.5%Reduced
Bank of America Corp1,226,737$123.5M0.01%−126,262−9.3%Reduced
Bank of New York Mellon Corp1,197,473$120.5M0.02%+40,723+3.5%Added
Eventide Asset Management, LLC1,196,494$120.4M2.11%+14,819+1.3%Added
FIL Ltd1,165,464$117.3M0.10%−1,224,737−51.2%Reduced
Wellington Management Group LLP1,159,699$116.7M0.02%−62,928−5.1%Reduced
Macquarie Group Ltd1,130,923$113.8M0.14%−1,231,182−52.1%Reduced
Marshall Wace, LLP1,113,361$112.0M0.13%+417,124+59.9%Added
Qube Research & Technologies Ltd1,082,050$108.9M0.15%+1,082,050New
Morgan Stanley1,043,791$105.0M0.01%−15,865−1.5%Reduced
Summit Partners Public Asset Management, LLC1,008,937$101.5M3.96%+304,571+43.2%Added
Northern Trust Corp969,800$97.6M0.01%−714,038−42.4%Reduced
Hood River Capital Management LLC899,603$90.5M1.26%−658,683−42.3%Reduced
TimesSquare Capital Management, LLC873,491$87.9M1.27%−190,657−17.9%Reduced
Palo Alto Investors LP865,113$87.1M18.52%−122,040−12.4%Reduced
Maverick Capital LtdSuperinvestorMaverick Capital804,133$80.9M1.24%+379,008+89.2%Added
Loomis Sayles & Co L P793,569$79.9M0.10%−215,897−21.4%Reduced
Raymond James Financial Inc784,551$79.0M0.03%+375,614+91.9%Added
BNP Paribas Arbitrage, SA754,160$75.9M0.06%+292,497+63.4%Added
Artia Global Partners LP752,712$75.8M19.48%+434,473+136.5%Added
Fiera Capital Corp748,037$75.3M0.26%+168,800+29.1%Added
HRT Financial LP729,597$73.4M0.32%+729,597New
Nwi Management LP720,000$72.5M6.65%+270,000+60.0%Added
Jennison Associates LLC715,606$72.0M0.04%−32,707−4.4%Reduced
Deerfield Management Company, L.P. (Series C)700,700$70.5M1.28%+242,700+53.0%Added
Polar Capital Holdings Plc697,960$70.2M0.37%−30,795−4.2%Reduced
UBS Asset Management Americas Inc695,961$70.0M0.01%+156,477+29.0%Added
Novo Holdings A/S680,000$68.4M4.83%−44,666−6.2%Reduced
Perceptive Advisors LLC650,252$65.4M2.46%+140,952+27.7%Added
Alyeska Investment Group, L.P.603,702$60.8M0.22%−131,298−17.9%Reduced
Nuveen, LLC588,987$59.3M0.02%−569,107−49.1%Reduced
Brown Advisory Inc579,846$58.4M0.08%−92,604−13.8%Reduced
Ensign Peak Advisors, Inc564,389$56.8M0.10%−25,010−4.2%Reduced
Cormorant Asset Management, LP540,000$54.3M4.05%+15,000+2.9%Added
Rock Springs Capital Management LP525,000$52.8M3.29%+9,100+1.8%Added
Long Focus Capital Management, LLC520,200$52.4M3.38%−110,600−17.5%Reduced
Alkeon Capital Management LLC500,000$50.3M0.24%+500,000New
Point72 Asset Management, L.P.490,667$49.4M0.12%+490,667New
Affinity Asset Advisors, LLC475,000$47.8M7.07%+335,000+239.3%Added
Castle Hook Partners LP452,656$45.6M0.67%+452,656New
Candriam Luxembourg S.C.A.438,688$44.2M0.25%−16,720−3.7%Reduced
SEI Investments Co433,628$43.6M0.05%+37,649+9.5%Added
Eagle Health Investments LP428,600$43.1M10.65%−14,700−3.3%Reduced
Royal Bank of Canada427,801$43.1M0.01%+182,539+74.4%Added
New York State Common Retirement Fund427,753$43.0M0.06%+72,031+20.2%Added
Dimensional Fund Advisors LP411,744$41.4M0.01%+39,744+10.7%Added
Voya Investment Management LLC407,679$41.0M0.04%−177,749−30.4%Reduced
TD Asset Management Inc395,194$39.8M0.03%−107,038−21.3%Reduced
Two Sigma Investments, LP376,508$37.9M0.07%−30,395−7.5%Reduced
First Turn Management, LLC372,672$37.5M7.00%−28,957−7.2%Reduced
Envestnet Asset Management Inc365,827$36.8M0.01%+40,520+12.5%Added
Patient Square Capital LP358,800$36.1M13.02%+28,550+8.6%Added
Swiss National Bank347,400$35.0M0.02%+18,100+5.5%Added
Weiss Asset Management LP339,825$34.2M0.54%+339,825New
Los Angeles Capital Management LLC330,800$33.3M0.12%+318,716+2,637.5%Added
Sofinnova Investments, Inc.313,923$31.6M2.15%+9,669+3.2%Added
Voloridge Investment Management, LLC313,053$31.5M0.12%+310,376+11,594.2%Added
Standard Life Aberdeen plc309,749$31.2M0.05%−26,608−7.9%Reduced
Renaissance Technologies LLC308,687$31.1M0.04%+308,687New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.302,065$30.4M0.07%−311,204−50.7%Reduced
Allspring Global Investments Holdings, LLC304,310$29.7M0.05%−134,364−30.6%Reduced
UBS Group AG293,454$29.5M0.01%−184,182−38.6%Reduced
Cubist Systematic Strategies, LLC283,102$28.5M0.31%+283,102New
C WorldWide Group Holding A/S271,110$27.3M0.37%−50,000−15.6%Reduced