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INSMED Inc

INSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001104506

In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q1 2026

Institutional positions in INSMED Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
675
+8 vs. Q4 2025
Shares held
220.9M
+27.6M (+14.3%) vs. Q4 2025
Total value
$35.7B
+$2.06B (+6.1%) vs. Q4 2025
New holders
101
288 more added
Sold out
93
216 more reduced

11 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 675 institutions
Q1 2021: 199 institutionsQ2 2021: 203 institutionsQ3 2021: 193 institutionsQ4 2021: 214 institutionsQ1 2022: 224 institutionsQ2 2022: 214 institutionsQ3 2022: 238 institutionsQ4 2022: 225 institutionsQ1 2023: 230 institutionsQ2 2023: 223 institutionsQ3 2023: 252 institutionsQ4 2023: 271 institutionsQ1 2024: 288 institutionsQ2 2024: 378 institutionsQ3 2024: 414 institutionsQ4 2024: 439 institutionsQ1 2025: 442 institutionsQ2 2025: 516 institutionsQ3 2025: 566 institutionsQ4 2025: 678 institutionsQ1 2026: 675 institutionsQ2 2026: 667 institutions
Value heldQ1 2026: $35.7B
Q1 2021: $3.63BQ2 2021: $3.46BQ3 2021: $3.40BQ4 2021: $3.36BQ1 2022: $2.97BQ2 2022: $2.55BQ3 2022: $2.74BQ4 2022: $2.87BQ1 2023: $2.48BQ2 2023: $3.09BQ3 2023: $3.72BQ4 2023: $4.64BQ1 2024: $4.07BQ2 2024: $11.7BQ3 2024: $13.7BQ4 2024: $13.3BQ1 2025: $15.3BQ2 2025: $21.2BQ3 2025: $30.3BQ4 2025: $37.8BQ1 2026: $35.7BQ2 2026: $23.8B
Institutions holding INSM and their total value by quarter
QuarterHoldersValue
Q2 2026667$23.8B
Q1 2026675$35.7B
Q4 2025678$37.8B
Q3 2025566$30.3B
Q2 2025516$21.2B
Q1 2025442$15.3B
Q4 2024439$13.3B
Q3 2024414$13.7B
Q2 2024378$11.7B
Q1 2024288$4.07B
Q4 2023271$4.64B
Q3 2023252$3.72B
Q2 2023223$3.09B
Q1 2023230$2.48B
Q4 2022225$2.87B
Q3 2022238$2.74B
Q2 2022214$2.55B
Q1 2022224$2.97B
Q4 2021214$3.36B
Q3 2021193$3.40B
Q2 2021203$3.46B
Q1 2021199$3.63B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q4 2025.

Institutions holding INSM in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
JPMorgan Chase & Co24,150,499$3.70B0.25%+950,987+4.1%Added
BlackRock, Inc.16,678,146$2.73B0.05%+1,613,094+10.7%Added
Darwin Global Management, Ltd.16,805,184$2.58B68.33%−4,128,093−19.7%Reduced
FMR LLC13,160,167$2.15B0.11%+3,232,231+32.6%Added
Vanguard Portfolio Management LLC10,371,802$1.70B0.09%+10,371,802New
Vanguard Capital Management LLC9,642,131$1.58B0.04%+9,642,131New
Baker Bros. Advisors LP7,421,111$1.21B6.97%+828,365+12.6%Added
Artisan Partners Limited Partnership6,527,301$1.07B1.74%+1,683,552+34.8%Added
Invesco Ltd.6,512,889$1.06B0.10%−1,005,449−13.4%Reduced
D. E. Shaw & Co., Inc.5,625,825$919.9M0.72%+1,274,830+29.3%Added
Capital International Investors5,595,194$914.9M0.21%+443,523+8.6%Added
State Street Corp5,551,699$907.8M0.03%+349,955+6.7%Added
RTW Investments, LP4,842,880$791.9M7.88%+10.0%Added
Geode Capital Management, LLC4,450,389$733.3M0.05%+151,337+3.5%Added
Price T Rowe Associates Inc3,092,807$505.7M0.06%−946,659−23.4%Reduced
Ameriprise Financial Inc3,057,718$500.0M0.12%+1,088,861+55.3%Added
Franklin Resources Inc2,617,251$428.0M0.10%−138,285−5.0%Reduced
Citadel Advisors LLC2,182,571$356.9M0.25%+1,025,276+88.6%Added
Orbis Allan Gray Ltd1,872,824$306.2M1.29%−2,307,133−55.2%Reduced
UBS Group AG1,737,481$284.1M0.05%−130,154−7.0%Reduced
Bank of America Corp1,502,281$245.7M0.02%−223,400−12.9%Reduced
Integral Health Asset Management, LLC1,500,000$245.3M12.98%+250,000+20.0%Added
Westfield Capital Management Co LP1,468,459$240.1M1.01%+1,035,938+239.5%Added
SEI Investments Co1,395,794$228.2M0.21%+505,624+56.8%Added
Capital World Investors1,362,291$222.7M0.03%+1,362,291New
Vanguard Fiduciary Trust Co1,354,516$221.5M0.06%+1,354,516New
Morgan Stanley1,331,542$217.7M0.01%−300,364−18.4%Reduced
Northern Trust Corp1,294,000$211.6M0.03%+55,562+4.5%Added
Castle Hook Partners LP1,269,754$207.6M4.20%+16,186+1.3%Added
Bank of New York Mellon Corp1,262,749$206.5M0.04%−127,293−9.2%Reduced
Paradigm Biocapital Advisors LP1,254,488$205.1M4.19%+1,254,488New
UBS Asset Management Americas Inc1,215,025$198.7M0.04%+271,719+28.8%Added
Millennium Management LLC1,157,786$189.3M0.14%−153,868−11.7%Reduced
Duquesne Family Office LLCSuperinvestorDuquesne Family Office1,154,090$188.7M6.43%−327,662−22.1%Reduced
Nomura Asset Management International Inc.1,143,739$187.0M0.32%−39,290−3.3%Reduced
Pictet Asset Management Holding SA1,102,248$178.7M0.19%+143,285+14.9%Added
Charles Schwab Investment Management Inc1,069,390$174.9M0.03%+42,035+4.1%Added
Fiera Capital Corp1,021,970$167.1M0.57%+29,078+2.9%Added
Nwi Management LP1,014,000$165.8M10.14%+25,540+2.6%Added
Goldman Sachs Group Inc942,646$154.1M0.02%−302,267−24.3%Reduced
American Century Companies Inc925,799$151.4M0.08%+740,709+400.2%Added
Principal Financial Group Inc916,464$149.9M0.08%+145,106+18.8%Added
William Blair Investment Management, LLC902,666$147.6M0.49%−318,430−26.1%Reduced
Adage Capital Partners GP, L.L.C.900,000$147.2M0.23%+600,000+200.0%Added
FIL Ltd828,947$135.5M0.11%−9,562−1.1%Reduced
Amundi804,977$131.6M0.04%−112,021−12.2%Reduced
Legal & General Group Plc787,079$128.7M0.03%+246,766+45.7%Added
Raymond James Financial Inc775,148$121.4M0.04%−4,106−0.5%Reduced
Alliancebernstein L.P.688,734$119.9M0.04%+46,015+7.2%Added
Hood River Capital Management LLC688,554$112.6M1.13%+50,977+8.0%Added
AQR Capital Management LLC675,485$108.8M0.05%+207,225+44.3%Added
Summit Partners Public Asset Management, LLC653,445$106.9M4.94%−255,635−28.1%Reduced
Clearbridge Investments, LLC643,435$105.2M0.09%−175,576−21.4%Reduced
Artia Global Partners LP628,712$102.8M23.18%−53,500−7.8%Reduced
Swiss National Bank625,912$102.3M0.06%+46,800+8.1%Added
GW&K Investment Management, LLC623,048$101.9M0.90%+140,378+29.1%Added
Jennison Associates LLC604,694$98.9M0.07%+42,398+7.5%Added
BNP Paribas Arbitrage, SA604,600$98.9M0.07%−310,819−34.0%Reduced
Wells Fargo & Company597,384$97.7M0.02%+10,733+1.8%Added
TimesSquare Capital Management, LLC584,798$95.6M1.62%+94,292+19.2%Added
Deutsche Bank AG562,474$92.0M0.03%−27,556−4.7%Reduced
Eventide Asset Management, LLC546,310$89.3M1.48%+62,721+13.0%Added
Federated Hermes, Inc.538,257$88.0M0.14%−94,041−14.9%Reduced
Nuveen, LLC534,750$87.4M0.02%−115,654−17.8%Reduced
Royal Bank of Canada523,101$85.5M0.02%+16,290+3.2%Added
Sumitomo Mitsui Trust Holdings, Inc.501,282$82.0M0.05%+65,840+15.1%Added
Ensign Peak Advisors, Inc499,756$81.7M0.15%+117,554+30.8%Added
Affinity Asset Advisors, LLC480,000$78.5M4.60%+30,000+6.7%Added
Frontier Capital Management Co LLC469,561$76.8M0.79%+184,717+64.8%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.467,753$76.5M0.09%+139,425+42.5%Added
Janus Henderson Group PLC419,304$68.6M0.03%−381,251−47.6%Reduced
Samlyn Capital, LLC417,205$68.2M1.17%+47,630+12.9%Added
Palo Alto Investors LP415,269$67.9M10.39%−74,213−15.2%Reduced
Candriam Luxembourg S.C.A.401,735$65.7M0.34%+693+0.2%Added
Dimensional Fund Advisors LP400,900$65.5M0.01%+1,827+0.5%Added
Wellington Management Group LLP399,044$65.3M0.01%−87,094−17.9%Reduced
Lord, Abbett & Co. LLC397,261$65.0M0.21%−323,637−44.9%Reduced
Victory Capital Management Inc396,245$64.8M0.04%−250,469−38.7%Reduced
Polar Capital Holdings Plc368,107$60.2M0.26%+23,879+6.9%Added
Gateway Investment Advisers LLC365,000$59.7M0.67%00.0%Unchanged
Vanguard Asset Management, Ltd360,075$58.9M0.05%+360,075New
Sofinnova Investments, Inc.346,075$56.6M2.84%+189,274+120.7%Added
California Public Employees Retirement System344,612$56.4M0.03%−10,297−2.9%Reduced
Rock Springs Capital Management LP314,300$51.4M3.03%−4,950−1.6%Reduced
Marshall Wace, LLP312,565$51.1M0.05%−77,316−19.8%Reduced
National Pension Service311,881$51.0M0.04%+31,439+11.2%Added
California State Teachers Retirement System303,182$49.6M0.05%−7,148−2.3%Reduced
Nearwater Capital Markets, Ltd300,000$49.1M1.16%−200,000−40.0%Reduced
Envestnet Asset Management Inc299,925$49.0M0.01%+23,820+8.6%Added
Bridgewater Associates, LP295,579$48.3M0.22%+295,579New
New York State Common Retirement Fund293,546$48.0M0.07%+17,262+6.2%Added
Allspring Global Investments Holdings, LLC282,734$46.6M0.08%+62,650+28.5%Added
ProShare Advisors LLC283,141$46.3M0.07%−57,599−16.9%Reduced
Standard Life Aberdeen plc277,016$45.3M0.07%+23,904+9.4%Added
Barclays PLC275,731$45.1M0.02%−168,975−38.0%Reduced
Rhumbline Advisers272,615$44.6M0.04%+4,289+1.6%Added
Neuberger Berman Group LLC270,700$44.3M0.03%+62,831+30.2%Added
Tang Capital Management LLC260,000$42.5M2.16%+200,000+333.3%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.255,247$41.7M0.03%+32,981+14.8%Added
First Turn Management, LLC248,475$40.6M4.54%−15,818−6.0%Reduced