INSMED Inc
INSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001104506
In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in INSMED Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 678
- +121 vs. Q3 2025
- Shares held
- 217.4M
- +6.76M (+3.2%) vs. Q3 2025
- Total value
- $37.8B
- +$7.55B (+24.9%) vs. Q3 2025
- New holders
- 202
- 241 more added
- Sold out
- 81
- 180 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 667 | $23.8B |
| Q1 2026 | 675 | $35.7B |
| Q4 2025 | 678 | $37.8B |
| Q3 2025 | 566 | $30.3B |
| Q2 2025 | 516 | $21.2B |
| Q1 2025 | 442 | $15.3B |
| Q4 2024 | 439 | $13.3B |
| Q3 2024 | 414 | $13.7B |
| Q2 2024 | 378 | $11.7B |
| Q1 2024 | 288 | $4.07B |
| Q4 2023 | 271 | $4.64B |
| Q3 2023 | 252 | $3.72B |
| Q2 2023 | 223 | $3.09B |
| Q1 2023 | 230 | $2.48B |
| Q4 2022 | 225 | $2.87B |
| Q3 2022 | 238 | $2.74B |
| Q2 2022 | 214 | $2.55B |
| Q1 2022 | 224 | $2.97B |
| Q4 2021 | 214 | $3.36B |
| Q3 2021 | 193 | $3.40B |
| Q2 2021 | 203 | $3.46B |
| Q1 2021 | 199 | $3.63B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| IFM Investors Pty Ltd | 40,165 | $6.99M | 0.06% | +40,165 | New |
| Legato Capital Management LLC | 40,006 | $6.96M | 0.60% | +5,174+14.9% | Added |
| Assetmark, Inc | 39,732 | $6.91M | 0.01% | +4,438+12.6% | Added |
| HighVista Strategies LLC | 39,400 | $6.86M | 1.77% | −10,549−21.1% | Reduced |
| Cetera Investment Advisers | 38,443 | $6.69M | 0.01% | −2,728−6.6% | Reduced |
| Daiwa Securities Group Inc. | 38,251 | $6.66M | 0.02% | +34,648+961.6% | Added |
| Bamco Inc | 38,200 | $6.65M | 0.02% | 00.0% | Unchanged |
| Thornburg Investment Management Inc | 37,971 | $6.61M | 0.08% | −6,077−13.8% | Reduced |
| British Columbia Investment Management Corp | 37,507 | $6.53M | 0.03% | +37,507 | New |
| Natixis Advisors, L.P. | 37,168 | $6.47M | 0.01% | −2,282−5.8% | Reduced |
| Simplify Asset Management Inc. | 36,890 | $6.42M | 0.11% | +17,226+87.6% | Added |
| Brinker Capital Investments, LLC | 36,586 | $6.37M | 0.05% | −107−0.3% | Reduced |
| Toronto Dominion Bank | 36,306 | $6.32M | 0.01% | +36,306 | New |
| Andra AP-fonden | 36,300 | $6.32M | 0.08% | +36,300 | New |
| Freestone Grove Partners LP | 36,200 | $6.30M | 0.05% | +36,200 | New |
| Nwam LLC | 38,982 | $6.23M | 0.35% | −10,556−21.3% | Reduced |
| Mariner, LLC | 35,272 | $6.14M | 0.01% | +6,403+22.2% | Added |
| MML Investors Services, LLC | 34,190 | $5.95M | 0.01% | −6,810−16.6% | Reduced |
| KBC Group NV | 34,013 | $5.92M | 0.01% | +24,396+253.7% | Added |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 33,773 | $5.88M | 0.01% | +33,773 | New |
| Teacher Retirement System of Texas | 33,219 | $5.78M | 0.02% | −13,418−28.8% | Reduced |
| Calamos Advisors LLC | 32,155 | $5.60M | 0.02% | −3,060−8.7% | Reduced |
| Kennedy Capital Management, Inc. | 32,049 | $5.58M | 0.12% | +1,695+5.6% | Added |
| Utah Retirement Systems | 32,001 | $5.57M | 0.05% | +1,272+4.1% | Added |
| BI Asset Management Fondsmaeglerselskab A/S | 30,527 | $5.31M | 0.05% | −6,897−18.4% | Reduced |
| Nomura Holdings Inc | 30,485 | $5.31M | 0.02% | +30,485 | New |
| PensionDanmark Pensionsforsikringsaktieselskab | 30,295 | $5.27M | 0.05% | +30,295 | New |
| Caisse de Depot Et Placement du Quebec | 29,500 | $5.13M | 0.01% | −134,900−82.1% | Reduced |
| GordonMD Global Investments LP | 28,587 | $4.98M | 3.57% | +28,587 | New |
| KVP Capital Advisors, LP | 28,497 | $4.96M | 5.12% | +28,497 | New |
| HealthInvest Partners AB | 27,873 | $4.85M | 1.55% | +27,873 | New |
| Profund Advisors LLC | 27,844 | $4.85M | 0.15% | +16,471+144.8% | Added |
| Atomi Financial Group, Inc. | 27,651 | $4.81M | 0.14% | +3,912+16.5% | Added |
| Pathstone Holdings, LLC | 26,954 | $4.69M | 0.02% | −4,667−14.8% | Reduced |
| iA Global Asset Management Inc. | 26,682 | $4.64M | 0.06% | +26,516+15,973.5% | Added |
| McRae Capital Management Inc | 26,675 | $4.64M | 0.95% | −520−1.9% | Reduced |
| SummitTX Capital, L.P. | 25,967 | $4.52M | 0.14% | +17,167+195.1% | Added |
| Renaissance Technologies LLC | 25,900 | $4.51M | 0.01% | −326,987−92.7% | Reduced |
| Acuta Capital Partners, LLC | 25,878 | $4.50M | 3.06% | −12,714−32.9% | Reduced |
| OrbiMed Advisors LLC | 25,400 | $4.42M | 0.09% | +11,941+88.7% | Added |
| Shelton Capital Management | 24,319 | $4.23M | 0.08% | +24,319 | New |
| Sumitomo Mitsui DS Asset Management Company, Ltd | 22,303 | $3.88M | 0.03% | +22,303 | New |
| PEAK6 LLC | 22,190 | $3.86M | 0.11% | +22,190 | New |
| O'Shaughnessy Asset Management, LLC | 21,929 | $3.82M | 0.02% | +8,703+65.8% | Added |
| Campbell & CO Investment Adviser LLC | 21,910 | $3.81M | 0.18% | +2,850+15.0% | Added |
| EFG International AG | 21,869 | $3.81M | 0.07% | +21,869 | New |
| Gotham Asset Management, LLC | 21,762 | $3.79M | 0.01% | +20,113+1,219.7% | Added |
| Mackenzie Financial Corp | 21,620 | $3.76M | 0.00% | +4,801+28.5% | Added |
| Sanctuary Advisors, LLC | 21,336 | $3.71M | 0.02% | +1,802+9.2% | Added |
| Toroso Investments, LLC | 21,310 | $3.71M | 0.02% | +10,512+97.4% | Added |
| ASR Vermogensbeheer N.V. | 21,108 | $3.67M | 0.04% | +21,108 | New |
| Canada Pension Plan Investment Board | 21,000 | $3.65M | 0.00% | −41,013−66.1% | Reduced |
| CI Private Wealth, LLC | 20,865 | $3.63M | 0.00% | +5,305+34.1% | Added |
| Rakuten Investment Management, Inc. | 20,466 | $3.61M | 0.01% | +20,466 | New |
| Storebrand Asset Management AS | 20,627 | $3.59M | 0.01% | +20,627 | New |
| SBI Okasan Asset Management Co.Ltd. | 20,200 | $3.56M | 0.20% | +20,200 | New |
| Atria Investments LLC | 20,385 | $3.55M | 0.04% | −1,028−4.8% | Reduced |
| Next Century Growth Investors LLC | 20,301 | $3.53M | 0.25% | +4,452+28.1% | Added |
| Nordea Investment Management AB | 20,008 | $3.49M | 0.00% | +20,008 | New |
| Brown Advisory Inc | 19,989 | $3.48M | 0.00% | −6,120−23.4% | Reduced |
| Baird Financial Group, Inc. | 19,684 | $3.43M | 0.01% | −2,702−12.1% | Reduced |
| Silvant Capital Management LLC | 19,584 | $3.41M | 0.12% | +19,584 | New |
| Quantinno Capital Management LP | 19,541 | $3.40M | 0.01% | +6,763+52.9% | Added |
| Cerity Partners LLC | 19,399 | $3.38M | 0.00% | −1,962−9.2% | Reduced |
| Advisor Group Holdings, Inc. | 19,276 | $3.35M | 0.00% | −3,472−15.3% | Reduced |
| Public Employees Retirement Association of Colorado | 19,020 | $3.31M | 0.01% | 00.0% | Unchanged |
| Cinctive Capital Management LP | 17,945 | $3.12M | 0.18% | −48,236−72.9% | Reduced |
| Avidity Partners Management LP | 17,700 | $3.08M | 0.89% | +6,100+52.6% | Added |
| CIBC World Markets Corp | 17,694 | $3.08M | 0.02% | +17,694 | New |
| Walleye Trading LLC | 17,657 | $3.07M | 0.05% | −3,428−16.3% | Reduced |
| Nisa Investment Advisors, LLC | 17,542 | $3.05M | 0.01% | +7,076+67.6% | Added |
| Harvest Fund Management Co., Ltd | 17,291 | $3.01M | 0.11% | +14,454+509.5% | Added |
| Rockefeller Capital Management L.P. | 16,775 | $2.92M | 0.01% | +7,863+88.2% | Added |
| Amalgamated Bank | 16,743 | $2.91M | 0.02% | +2,210+15.2% | Added |
| Tobam | 16,308 | $2.84M | 0.70% | −2,789−14.6% | Reduced |
| Verition Fund Management LLC | 16,043 | $2.79M | 0.02% | −12,109−43.0% | Reduced |
| Allstate Corp | 15,870 | $2.76M | 0.04% | +15,870 | New |
| Walleye Capital LLC | 15,820 | $2.75M | 0.02% | +8,890+128.3% | Added |
| Truist Financial Corp | 15,733 | $2.74M | 0.00% | −23,330−59.7% | Reduced |
| Pacer Advisors, Inc. | 15,583 | $2.71M | 0.01% | +15,583 | New |
| West Michigan Advisors, LLC | 15,418 | $2.68M | 0.62% | −2,201−12.5% | Reduced |
| Keybank National Association | 15,166 | $2.64M | 0.01% | −1,550−9.3% | Reduced |
| Federation des caisses Desjardins du Quebec | 15,142 | $2.63M | 0.01% | +1,919+14.5% | Added |
| Dark Forest Capital Management LP | 14,732 | $2.56M | 0.12% | +5,490+59.4% | Added |
| Louisiana State Employees Retirement System | 14,300 | $2.49M | 0.04% | +14,300 | New |
| Investment Management Corp of Ontario | 14,221 | $2.48M | 0.03% | +14,221 | New |
| Swiss Life Asset Management Ltd | 14,004 | $2.44M | 0.01% | +5,288+60.7% | Added |
| Eurizon Capital SGR S.p.A. | 13,969 | $2.43M | 0.01% | +13,969 | New |
| Credit Agricole S A | 13,927 | $2.42M | 0.01% | +13,927 | New |
| Bellevue Group AG | 13,915 | $2.42M | 0.05% | −6,336−31.3% | Reduced |
| Oak Ridge Investments LLC | 13,813 | $2.40M | 0.15% | −8,323−37.6% | Reduced |
| Jane Street Group, LLC | 13,505 | $2.35M | 0.00% | −778,229−98.3% | Reduced |
| Main Management ETF Advisors, LLC | 13,311 | $2.32M | 0.08% | +136+1.0% | Added |
| Fideuram Asset Management (Ireland) dac | 11,158 | $2.31M | 0.19% | +11,158 | New |
| Emerald Mutual Fund Advisers Trust | 13,241 | $2.30M | 0.11% | +919+7.5% | Added |
| F/M Investments LLC | 13,241 | $2.30M | 0.09% | +2,174+19.6% | Added |
| Oppenheimer Asset Management Inc. | 13,151 | $2.29M | 0.03% | −2,702−17.0% | Reduced |
| Fedenia Advisers LLC | 12,927 | $2.25M | 0.86% | +12,927 | New |
| EAM Investors, LLC | 12,924 | $2.25M | 0.25% | −35,048−73.1% | Reduced |
| MetLife Investment Management | 12,891 | $2.24M | 0.01% | +1,518+13.3% | Added |