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INSMED Inc

INSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001104506

In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q2 2025

Institutional positions in INSMED Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
516
+78 vs. Q1 2025
Shares held
210.4M
+10.8M (+5.4%) vs. Q1 2025
Total value
$21.2B
+$5.90B (+38.7%) vs. Q1 2025
New holders
130
166 more added
Sold out
52
188 more reduced

4 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 516 institutions
Q1 2021: 199 institutionsQ2 2021: 203 institutionsQ3 2021: 193 institutionsQ4 2021: 214 institutionsQ1 2022: 224 institutionsQ2 2022: 214 institutionsQ3 2022: 238 institutionsQ4 2022: 225 institutionsQ1 2023: 230 institutionsQ2 2023: 223 institutionsQ3 2023: 252 institutionsQ4 2023: 271 institutionsQ1 2024: 288 institutionsQ2 2024: 378 institutionsQ3 2024: 414 institutionsQ4 2024: 439 institutionsQ1 2025: 442 institutionsQ2 2025: 516 institutionsQ3 2025: 566 institutionsQ4 2025: 678 institutionsQ1 2026: 675 institutionsQ2 2026: 667 institutions
Value heldQ2 2025: $21.2B
Q1 2021: $3.63BQ2 2021: $3.46BQ3 2021: $3.40BQ4 2021: $3.36BQ1 2022: $2.97BQ2 2022: $2.55BQ3 2022: $2.74BQ4 2022: $2.87BQ1 2023: $2.48BQ2 2023: $3.09BQ3 2023: $3.72BQ4 2023: $4.64BQ1 2024: $4.07BQ2 2024: $11.7BQ3 2024: $13.7BQ4 2024: $13.3BQ1 2025: $15.3BQ2 2025: $21.2BQ3 2025: $30.3BQ4 2025: $37.8BQ1 2026: $35.7BQ2 2026: $23.8B
Institutions holding INSM and their total value by quarter
QuarterHoldersValue
Q2 2026667$23.8B
Q1 2026675$35.7B
Q4 2025678$37.8B
Q3 2025566$30.3B
Q2 2025516$21.2B
Q1 2025442$15.3B
Q4 2024439$13.3B
Q3 2024414$13.7B
Q2 2024378$11.7B
Q1 2024288$4.07B
Q4 2023271$4.64B
Q3 2023252$3.72B
Q2 2023223$3.09B
Q1 2023230$2.48B
Q4 2022225$2.87B
Q3 2022238$2.74B
Q2 2022214$2.55B
Q1 2022224$2.97B
Q4 2021214$3.36B
Q3 2021193$3.40B
Q2 2021203$3.46B
Q1 2021199$3.63B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q1 2025.

Institutions holding INSM in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Franklin Resources Inc2,350,133$236.5M0.06%+201,849+9.4%Added
Adage Capital Partners GP, L.L.C.2,859,452$287.8M0.48%−587,492−17.0%Reduced
Ameriprise Financial Inc2,957,973$297.7M0.07%+6,351+0.2%Added
RTW Investments, LP3,084,558$310.4M4.42%+70,000+2.3%Added
Artisan Partners Limited Partnership3,314,341$333.6M0.50%+97,073+3.0%Added
Geode Capital Management, LLC3,340,707$336.3M0.02%−948,028−22.1%Reduced
D. E. Shaw & Co., Inc.3,422,619$344.5M0.34%+2,687,739+365.7%Added
State Street Corp4,277,888$430.5M0.02%−1,469,405−25.6%Reduced
FMR LLC5,093,261$512.6M0.03%+1,698,877+50.0%Added
Capital International Investors7,478,859$752.7M0.13%+280,374+3.9%Added
Baker Bros. Advisors LP7,712,900$776.2M7.53%+2,332,274+43.3%Added
BlackRock, Inc.11,142,432$1.12B0.02%−4,906,450−30.6%Reduced
Price T Rowe Associates Inc11,230,705$1.13B0.13%−1,692,836−13.1%Reduced
JPMorgan Chase & Co15,636,399$1.57B0.11%+9,282,377+146.1%Added
Vanguard Group Inc17,644,492$1.78B0.03%−623,630−3.4%Reduced
Darwin Global Management, Ltd.19,344,621$1.92B80.75%+3,946,646+25.6%Added
T. Rowe Price Investment Management, Inc.0$00.00%−1,476,948−100.0%Sold out
Vestal Point Capital, LP0$00.00%−1,075,000−100.0%Sold out
1832 Asset Management L.P.0$00.00%−487,800−100.0%Sold out
Paradigm Biocapital Advisors LP0$00.00%−451,359−100.0%Sold out
Soros Fund Management LLCSuperinvestorSoros Fund Management0$00.00%−307,211−100.0%Sold out
Kingdon Capital Management, L.L.C.0$00.00%−215,000−100.0%Sold out
Ra Capital Management, L.P.0$00.00%−200,000−100.0%Sold out
Cutter Capital Management, LP0$00.00%−186,384−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−132,925−100.0%Sold out
Intech Investment Management LLC0$00.00%−101,979−100.0%Sold out
Tri Locum Partners LP0$00.00%−101,859−100.0%Sold out
Atika Capital Management LLC0$00.00%−96,000−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−84,466−100.0%Sold out
CIBC World Markets Corp0$00.00%−38,258−100.0%Sold out
Parkman Healthcare Partners LLC0$00.00%−37,901−100.0%Sold out
Hennion & Walsh Asset Management, Inc.0$00.00%−35,704−100.0%Sold out
Springhill Fund Asset Management (HK) Co Ltd0$00.00%−19,192−100.0%Sold out
Ameritas Investment Partners, Inc.0$00.00%−17,551−100.0%Sold out
CenterBook Partners LP0$00.00%−15,991−100.0%Sold out
Simplex Trading, LLC0$00.00%−14,467−100.0%Sold out
Teachers Retirement System of the State of Kentucky0$00.00%−12,775−100.0%Sold out
SIH Partners, LLLP0$00.00%−11,415−100.0%Sold out
Allostery Investments LP0$00.00%−10,000−100.0%Sold out
Group One Trading, L.P.0$00.00%−7,361−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−6,074−100.0%Sold out
Caxton Associates LLP0$00.00%−5,785−100.0%Sold out
Cantor Fitzgerald, L. P.0$00.00%−5,060−100.0%Sold out
Syon Capital LLC0$00.00%−4,929−100.0%Sold out
Financial Advocates Investment Management0$00.00%−4,836−100.0%Sold out
Cresset Asset Management, LLC0$00.00%−4,083−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−3,997−100.0%Sold out
Banco BTG Pactual S.A.0$00.00%−3,285−100.0%Sold out
Ieq Capital, LLC0$00.00%−3,202−100.0%Sold out
TownSquare Capital, LLC0$00.00%−3,088−100.0%Sold out
Journey Strategic Wealth LLC0$00.00%−2,647−100.0%Sold out
State of Wyoming0$00.00%−1,667−100.0%Sold out
Strategic Investment Solutions, Inc.0$00.00%−1,040−100.0%Sold out
Optiver Holding B.V.0$00.00%−642−100.0%Sold out
V-Square Quantitative Management LLC0$00.00%−620−100.0%Sold out
Hexagon Capital Partners LLC0$00.00%−408−100.0%Sold out
Rothschild Investment LLC0$00.00%−240−100.0%Sold out
Wayfinding Financial, LLC0$00.00%−223−100.0%Sold out
Global Financial Private Client, LLC0$00.00%−88−100.0%Sold out
Mather Group, LLC.0$00.00%−70−100.0%Sold out
Highline Wealth Partners LLC0$00.00%−48−100.0%Sold out
Continuum Advisory, LLC0$00.00%−27−100.0%Sold out
Creative Financial Designs Inc0$00.00%−16−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−15−100.0%Sold out
Valley National Advisers Inc0$00.00%−22−100.0%Sold out
CoreCap Advisors, LLC0$00.00%−9−100.0%Sold out
Bogart Wealth, LLC0$00.00%−6−100.0%Sold out
CVA Family Office, LLC0$00.00%−6−100.0%Sold out
Orion Portfolio Solutions, LLC––––Not filed
Glenmede Trust Co NA––––Not filed
JCIC Asset Management Inc.––––Not filed
Lindbrook Capital, LLC––––Not filed