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INSMED Inc

INSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001104506

In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q1 2025

Institutional positions in INSMED Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
442
+9 vs. Q4 2024
Shares held
199.6M
+8.34M (+4.4%) vs. Q4 2024
Total value
$15.3B
+$2.05B (+15.5%) vs. Q4 2024
New holders
57
184 more added
Sold out
48
150 more reduced

6 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 442 institutions
Q1 2021: 199 institutionsQ2 2021: 203 institutionsQ3 2021: 193 institutionsQ4 2021: 214 institutionsQ1 2022: 224 institutionsQ2 2022: 214 institutionsQ3 2022: 238 institutionsQ4 2022: 225 institutionsQ1 2023: 230 institutionsQ2 2023: 223 institutionsQ3 2023: 252 institutionsQ4 2023: 271 institutionsQ1 2024: 288 institutionsQ2 2024: 378 institutionsQ3 2024: 414 institutionsQ4 2024: 439 institutionsQ1 2025: 442 institutionsQ2 2025: 516 institutionsQ3 2025: 566 institutionsQ4 2025: 678 institutionsQ1 2026: 675 institutionsQ2 2026: 667 institutions
Value heldQ1 2025: $15.3B
Q1 2021: $3.63BQ2 2021: $3.46BQ3 2021: $3.40BQ4 2021: $3.36BQ1 2022: $2.97BQ2 2022: $2.55BQ3 2022: $2.74BQ4 2022: $2.87BQ1 2023: $2.48BQ2 2023: $3.09BQ3 2023: $3.72BQ4 2023: $4.64BQ1 2024: $4.07BQ2 2024: $11.7BQ3 2024: $13.7BQ4 2024: $13.3BQ1 2025: $15.3BQ2 2025: $21.2BQ3 2025: $30.3BQ4 2025: $37.8BQ1 2026: $35.7BQ2 2026: $23.8B
Institutions holding INSM and their total value by quarter
QuarterHoldersValue
Q2 2026667$23.8B
Q1 2026675$35.7B
Q4 2025678$37.8B
Q3 2025566$30.3B
Q2 2025516$21.2B
Q1 2025442$15.3B
Q4 2024439$13.3B
Q3 2024414$13.7B
Q2 2024378$11.7B
Q1 2024288$4.07B
Q4 2023271$4.64B
Q3 2023252$3.72B
Q2 2023223$3.09B
Q1 2023230$2.48B
Q4 2022225$2.87B
Q3 2022238$2.74B
Q2 2022214$2.55B
Q1 2022224$2.97B
Q4 2021214$3.36B
Q3 2021193$3.40B
Q2 2021203$3.46B
Q1 2021199$3.63B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q4 2024.

Institutions holding INSM in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Soros Fund Management LLCSuperinvestorSoros Fund Management307,211$23.4M0.42%−147,878−32.5%Reduced
Panagora Asset Management Inc306,717$23.4M0.12%−10,445−3.3%Reduced
Sofinnova Investments, Inc.304,254$23.2M1.75%+47,973+18.7%Added
Rhumbline Advisers303,557$23.2M0.02%+15,220+5.3%Added
Russell Investments Group, Ltd.302,996$23.1M0.03%+170,842+129.3%Added
Comerica Bank290,275$22.1M0.09%+119,495+70.0%Added
Barclays PLC279,270$21.3M0.01%−75,166−21.2%Reduced
Citigroup Inc277,549$21.2M0.02%+30,106+12.2%Added
Soleus Capital Management, L.P.274,272$20.9M1.64%−46,000−14.4%Reduced
California Public Employees Retirement System265,477$20.3M0.01%+9,122+3.6%Added
B Group, Inc.262,500$20.0M17.40%−87,500−25.0%Reduced
Deep Track Capital, LP254,751$19.4M0.63%+254,751New
Woodline Partners LP248,770$19.0M0.12%+86,540+53.3%Added
Royal Bank of Canada245,262$18.7M0.00%+61,190+33.2%Added
Nicholas Investment Partners, LP223,931$17.1M1.76%+41,188+22.5%Added
Kingdon Capital Management, L.L.C.215,000$16.4M3.40%−10,000−4.4%Reduced
Wells Fargo & Company205,511$15.7M0.00%+44,802+27.9%Added
AXA S.A.203,857$15.6M0.05%−22,964−10.1%Reduced
Ra Capital Management, L.P.200,000$15.3M0.25%00.0%Unchanged
Federated Hermes, Inc.192,643$14.7M0.03%−43,193−18.3%Reduced
Granahan Investment Management Inc187,802$14.3M0.71%−21,552−10.3%Reduced
Cutter Capital Management, LP186,384$14.2M6.19%−24,500−11.6%Reduced
Rhenman & Partners Asset Management AB185,500$14.2M1.63%+124,000+201.6%Added
Peregrine Capital Management LLC180,993$13.8M0.46%−12,486−6.5%Reduced
Legal & General Group Plc180,202$13.7M0.00%+4,188+2.4%Added
Neuberger Berman Group LLC176,633$13.5M0.01%+27,392+18.4%Added
Segall Bryant & Hamill, LLC170,859$13.0M0.20%+31,814+22.9%Added
California State Teachers Retirement System157,698$12.0M0.01%+4,355+2.8%Added
Two Sigma Advisers, LP157,200$12.0M0.03%−169,300−51.9%Reduced
Prudential Financial Inc155,177$11.8M0.02%+8,455+5.8%Added
Bellevue Group AG150,550$11.5M0.26%−107,933−41.8%Reduced
WCM Investment Management, LLC144,379$11.3M0.03%−361−0.2%Reduced
Rafferty Asset Management, LLC145,984$11.1M0.05%−34,929−19.3%Reduced
Affinity Asset Advisors, LLC140,000$10.7M1.67%+90,000+180.0%Added
Readystate Asset Management LP134,569$10.3M0.52%+108,379+413.8%Added
Susquehanna Fundamental Investments, LLC132,925$10.1M0.17%−138,035−50.9%Reduced
Schroder Investment Management Group127,495$9.94M0.01%−140,568−52.4%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH129,187$9.86M0.02%+30,727+31.2%Added
State of Wisconsin Investment Board125,975$9.61M0.02%+3,864+3.2%Added
Jane Street Group, LLC124,587$9.50M0.02%−139,134−52.8%Reduced
Van Eck Associates Corp123,552$9.43M0.01%+4,318+3.6%Added
Mirae Asset Global ETFs Holdings Ltd.109,489$8.36M0.02%+4,176+4.0%Added
Avidity Partners Management LP107,000$8.16M1.68%−125,800−54.0%Reduced
Acuta Capital Partners, LLC106,074$8.09M9.38%+1,274+1.2%Added
Intech Investment Management LLC101,979$7.78M0.08%+30,752+43.2%Added
Tri Locum Partners LP101,859$7.77M3.99%+101,859New
MetLife Investment Management100,210$7.65M0.04%−3,219−3.1%Reduced
Tang Capital Management LLC100,000$7.63M0.42%00.0%Unchanged
Atika Capital Management LLC96,000$7.32M1.12%+96,000New
EFG Asset Management (North America) Corp.94,225$7.18M1.19%−13,400−12.5%Reduced
Royce & Associates LP90,027$6.87M0.07%00.0%Unchanged
Moody Aldrich Partners LLC89,020$6.79M1.42%+53,542+150.9%Added
Rice Hall James & Associates, LLC88,041$6.72M0.39%−819−0.9%Reduced
ExodusPoint Capital Management, LP87,783$6.70M0.09%+87,783New
StemPoint Capital LP87,059$6.64M2.12%−19,551−18.3%Reduced
Ally Bridge Group (NY) LLC85,110$6.49M5.85%−29,250−25.6%Reduced
Ikarian Capital, LLC84,800$6.47M2.11%−35,000−29.2%Reduced
Corebridge Financial, Inc.84,466$6.44M0.04%−1,253−1.5%Reduced
Axiom Investors LLC79,925$6.10M0.06%−3,949−4.7%Reduced
Mutual of America Capital Management LLC79,141$6.04M0.07%+2,093+2.7%Added
Allianz Asset Management GmbH75,284$5.74M0.01%+3,534+4.9%Added
Aquatic Capital Management LLC73,614$5.62M0.14%−17,654−19.3%Reduced
Harbor Capital Advisors, Inc.72,816$5.55M0.25%+13,216+22.2%Added
Creative Planning71,744$5.47M0.01%+15,034+26.5%Added
EAM Investors, LLC71,670$5.47M0.95%−294−0.4%Reduced
Thornburg Investment Management Inc68,840$5.25M0.07%−5,909−7.9%Reduced
First Light Asset Management, LLC68,153$5.20M0.59%−402,039−85.5%Reduced
Essex Investment Management Co LLC66,800$5.10M1.06%−530−0.8%Reduced
EAM Global Investors LLC61,508$4.69M1.28%+190.0%Added
Bamco Inc60,000$4.58M0.01%00.0%Unchanged
State of New Jersey Common Pension Fund D59,070$4.51M0.02%−4,991−7.8%Reduced
Castleark Management LLC53,860$4.11M0.14%+1,080+2.0%Added
Nwam LLC53,789$4.10M0.35%+17,693+49.0%Added
Hillsdale Investment Management Inc.51,900$3.96M0.20%−5,100−8.9%Reduced
AQR Capital Management LLC51,239$3.91M0.00%−12,932−20.2%Reduced
LPL Financial LLC51,213$3.91M0.00%+18,456+56.3%Added
DekaBank Deutsche Girozentrale50,000$3.86M0.01%00.0%Unchanged
Picton Mahoney Asset Management49,784$3.80M0.13%+887+1.8%Added
Handelsbanken Fonder AB49,181$3.75M0.02%+3,900+8.6%Added
Arizona State Retirement System48,678$3.71M0.02%+1,336+2.8%Added
Erste Asset Management GmbH47,600$3.71M0.05%00.0%Unchanged
Teacher Retirement System of Texas45,683$3.49M0.01%−2,654−5.5%Reduced
Pathstone Holdings, LLC45,533$3.47M0.02%+8,388+22.6%Added
ProShare Advisors LLC45,489$3.47M0.01%−11,502−20.2%Reduced
Truist Financial Corp45,074$3.44M0.01%+15,036+50.1%Added
Algert Global LLC44,424$3.39M0.08%−31,330−41.4%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)43,574$3.32M0.01%+98+0.2%Added
Great West Life Assurance Co42,458$3.25M0.01%+3,079+7.8%Added
Oak Ridge Investments LLC41,945$3.20M0.27%−14,691−25.9%Reduced
Legato Capital Management LLC41,857$3.19M0.43%+4,986+13.5%Added
Hudson Bay Capital Management LP40,170$3.06M0.02%−169,830−80.9%Reduced
Parallax Volatility Advisers, L.P.39,913$3.04M0.10%−30,624−43.4%Reduced
Assenagon Asset Management S.A.39,778$3.03M0.01%−485,415−92.4%Reduced
Calamos Advisors LLC39,301$3.00M0.01%+25,925+193.8%Added
Brinker Capital Investments, LLC38,735$2.96M0.03%+10,973+39.5%Added
Orion Portfolio Solutions, LLC38,735$2.96M0.03%+10,973+39.5%Added
CIBC World Markets Corp38,258$2.92M0.02%+22,123+137.1%Added
Parkman Healthcare Partners LLC37,901$2.89M0.34%+2,233+6.3%Added
State Board of Administration of Florida Retirement System37,632$2.87M0.01%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey37,100$2.83M0.03%+362+1.0%Added