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CytomX Therapeutics, Inc.

CTMX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001501989

No open-market purchases or sales by CytomX Therapeutics, Inc. insiders were filed in the last 90 days; 178 institutions reported holding it in 13F filings for Q2 2026, worth $799.0M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in CytomX Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
122
+19 vs. Q3 2025
Shares held
144.1M
+6.67M (+4.9%) vs. Q3 2025
Total value
$613.9M
+$175.5M (+40.0%) vs. Q3 2025
New holders
39
39 more added
Sold out
20
25 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CTMX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 122 institutions
Q1 2021: 126 institutionsQ2 2021: 122 institutionsQ3 2021: 114 institutionsQ4 2021: 110 institutionsQ1 2022: 119 institutionsQ2 2022: 99 institutionsQ3 2022: 84 institutionsQ4 2022: 81 institutionsQ1 2023: 76 institutionsQ2 2023: 67 institutionsQ3 2023: 62 institutionsQ4 2023: 68 institutionsQ1 2024: 88 institutionsQ2 2024: 74 institutionsQ3 2024: 69 institutionsQ4 2024: 70 institutionsQ1 2025: 66 institutionsQ2 2025: 83 institutionsQ3 2025: 103 institutionsQ4 2025: 122 institutionsQ1 2026: 179 institutionsQ2 2026: 178 institutions
Value heldQ4 2025: $613.9M
Q1 2021: $422.2MQ2 2021: $358.9MQ3 2021: $274.8MQ4 2021: $236.5MQ1 2022: $143.4MQ2 2022: $83.4MQ3 2022: $52.6MQ4 2022: $57.5MQ1 2023: $53.7MQ2 2023: $58.7MQ3 2023: $41.8MQ4 2023: $50.6MQ1 2024: $97.1MQ2 2024: $61.9MQ3 2024: $60.4MQ4 2024: $48.1MQ1 2025: $28.8MQ2 2025: $302.6MQ3 2025: $438.4MQ4 2025: $613.9MQ1 2026: $911.2MQ2 2026: $799.0M
Institutions holding CTMX and their total value by quarter
QuarterHoldersValue
Q2 2026178$799.0M
Q1 2026179$911.2M
Q4 2025122$613.9M
Q3 2025103$438.4M
Q2 202583$302.6M
Q1 202566$28.8M
Q4 202470$48.1M
Q3 202469$60.4M
Q2 202474$61.9M
Q1 202488$97.1M
Q4 202368$50.6M
Q3 202362$41.8M
Q2 202367$58.7M
Q1 202376$53.7M
Q4 202281$57.5M
Q3 202284$52.6M
Q2 202299$83.4M
Q1 2022119$143.4M
Q4 2021110$236.5M
Q3 2021114$274.8M
Q2 2021122$358.9M
Q1 2021126$422.2M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding CytomX Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding CTMX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Dimensional Fund Advisors LP1,289,656$5.49M0.00%+838,528+185.9%Added
Geode Capital Management, LLC1,525,666$6.50M0.00%−43,632−2.8%Reduced
Two Sigma Investments, LP1,560,755$6.65M0.01%+831,057+113.9%Added
Woodline Partners LP2,337,005$9.96M0.04%00.0%Unchanged
Goldman Sachs Group Inc2,460,944$10.5M0.00%+2,013,191+449.6%Added
Eversept Partners, LP2,507,090$10.7M0.60%+2,507,090New
Vivo Capital, LLC2,884,615$12.3M0.79%00.0%Unchanged
Ikarian Capital, LLC3,172,616$13.5M1.75%−200,000−5.9%Reduced
OrbiMed Advisors LLC3,525,650$15.0M0.31%−4,935,850−58.3%Reduced
BlackRock, Inc.3,669,393$15.6M0.00%+1,287,481+54.1%Added
Financial Engines Advisors L.L.C.3,828,717$16.3M0.03%+2,447,360+177.2%Added
Balyasny Asset Management LLC3,872,202$16.5M0.03%−40,879−1.0%Reduced
ADAR1 Capital Management, LLC4,182,769$17.8M1.33%+137,355+3.4%Added
Baker Bros. Advisors LP4,250,826$18.1M0.11%00.0%Unchanged
State Street Corp5,140,931$21.9M0.00%+4,495,949+697.1%Added
Point72 Asset Management, L.P.5,189,538$22.1M0.03%+1,120,963+27.6%Added
Commodore Capital LP7,692,300$32.8M2.18%00.0%Unchanged
Vanguard Group Inc8,475,584$36.1M0.00%−472,223−5.3%Reduced
Kynam Capital Management, LP8,966,077$38.2M2.49%+5,319,574+145.9%Added
Perceptive Advisors LLC9,680,185$41.2M0.76%00.0%Unchanged
VR Adviser, LLC15,561,500$66.3M3.27%00.0%Unchanged
FMR LLC24,688,109$105.2M0.01%+9,291,909+60.4%Added
Tang Capital Management LLC0$00.00%−11,065,662−100.0%Sold out
RTW Investments, LP0$00.00%−3,461,500−100.0%Sold out
Ra Capital Management, L.P.0$00.00%−2,661,331−100.0%Sold out
Renaissance Technologies LLC0$00.00%−2,545,260−100.0%Sold out
Prosight Management, LP0$00.00%−564,800−100.0%Sold out
Precision Wealth Strategies, LLC0$00.00%−237,081−100.0%Sold out
Diadema Partners LP0$00.00%−185,286−100.0%Sold out
Quadrature Capital Ltd0$00.00%−125,035−100.0%Sold out
Stonepine Capital Management, LLC0$00.00%−125,000−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−50,773−100.0%Sold out
Persistent Asset Partners Ltd0$00.00%−42,645−100.0%Sold out
Prudential Financial Inc0$00.00%−23,300−100.0%Sold out
BlueChip Wealth Advisors LLC0$00.00%−23,000−100.0%Sold out
Forefront Wealth Partners, LLC0$00.00%−18,109−100.0%Sold out
BIT Capital GmbH0$00.00%−16,285−100.0%Sold out
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors0$00.00%−10,747−100.0%Sold out
Meridian Wealth Management, LLC0$00.00%−10,000−100.0%Sold out
Private Wealth Asset Management, LLC0$00.00%−4,000−100.0%Sold out
Truist Financial Corp0$00.00%−12,500−100.0%Sold out
Advisory Services Network, LLC0$00.00%−274−100.0%Sold out