Skip to main content

CytomX Therapeutics, Inc.

CTMX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001501989

No open-market purchases or sales by CytomX Therapeutics, Inc. insiders were filed in the last 90 days; 178 institutions reported holding it in 13F filings for Q2 2026, worth $799.0M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in CytomX Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
122
+19 vs. Q3 2025
Shares held
144.1M
+6.67M (+4.9%) vs. Q3 2025
Total value
$613.9M
+$175.5M (+40.0%) vs. Q3 2025
New holders
39
39 more added
Sold out
20
25 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CTMX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 122 institutions
Q1 2021: 126 institutionsQ2 2021: 122 institutionsQ3 2021: 114 institutionsQ4 2021: 110 institutionsQ1 2022: 119 institutionsQ2 2022: 99 institutionsQ3 2022: 84 institutionsQ4 2022: 81 institutionsQ1 2023: 76 institutionsQ2 2023: 67 institutionsQ3 2023: 62 institutionsQ4 2023: 68 institutionsQ1 2024: 88 institutionsQ2 2024: 74 institutionsQ3 2024: 69 institutionsQ4 2024: 70 institutionsQ1 2025: 66 institutionsQ2 2025: 83 institutionsQ3 2025: 103 institutionsQ4 2025: 122 institutionsQ1 2026: 179 institutionsQ2 2026: 178 institutions
Value heldQ4 2025: $613.9M
Q1 2021: $422.2MQ2 2021: $358.9MQ3 2021: $274.8MQ4 2021: $236.5MQ1 2022: $143.4MQ2 2022: $83.4MQ3 2022: $52.6MQ4 2022: $57.5MQ1 2023: $53.7MQ2 2023: $58.7MQ3 2023: $41.8MQ4 2023: $50.6MQ1 2024: $97.1MQ2 2024: $61.9MQ3 2024: $60.4MQ4 2024: $48.1MQ1 2025: $28.8MQ2 2025: $302.6MQ3 2025: $438.4MQ4 2025: $613.9MQ1 2026: $911.2MQ2 2026: $799.0M
Institutions holding CTMX and their total value by quarter
QuarterHoldersValue
Q2 2026178$799.0M
Q1 2026179$911.2M
Q4 2025122$613.9M
Q3 2025103$438.4M
Q2 202583$302.6M
Q1 202566$28.8M
Q4 202470$48.1M
Q3 202469$60.4M
Q2 202474$61.9M
Q1 202488$97.1M
Q4 202368$50.6M
Q3 202362$41.8M
Q2 202367$58.7M
Q1 202376$53.7M
Q4 202281$57.5M
Q3 202284$52.6M
Q2 202299$83.4M
Q1 2022119$143.4M
Q4 2021110$236.5M
Q3 2021114$274.8M
Q2 2021122$358.9M
Q1 2021126$422.2M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding CytomX Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding CTMX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
CWM Advisors, LLC8$320.00%−522,474−100.0%Reduced
SBI Securities Co., Ltd.28$1190.00%−57−67.1%Reduced
Royal Bank of Canada214$1.00K0.00%−152,090−99.9%Reduced
Daiwa Securities Group Inc.564$2.00K0.00%+564New
BNP Paribas Arbitrage, SA2,825$12.0K0.00%+2,808+16,517.6%Added
GF Fund Management Co. Ltd.3,329$14.2K0.00%+3,329New
Caitong International Asset Management Co., Ltd4,690$20.0K0.00%+4,001+580.7%Added
Wells Fargo & Company6,605$28.1K0.00%+3,000+83.2%Added
Farther Finance Advisors, LLC7,875$33.5K0.00%−95−1.2%Reduced
Mirae Asset Global Investments Co., Ltd.8,233$35.1K0.00%+8,233New
Peregrine Asset Advisers, Inc.10,000$42.6K0.01%00.0%Unchanged
Brevan Howard Capital Management LP11,404$48.6K0.00%+11,404New
HSBC Holdings PLC12,230$52.1K0.00%+12,230New
IPG Investment Advisors LLC12,500$53.3K0.01%00.0%Unchanged
Nierenberg Investment Management Company, Inc.12,555$53.5K0.03%00.0%Unchanged
Bank of Nova Scotia13,661$58.2K0.00%+13,661New
Icapital Wealth LLC14,492$62.0K0.03%00.0%Unchanged
Victory Capital Management Inc14,722$62.7K0.00%+601+4.3%Added
Paces Ferry Wealth Advisors, LLC14,822$63.1K0.03%+14,822New
Evolve Private Wealth, LLC14,834$63.2K0.00%+14,834New
Mirae Asset Global ETFs Holdings Ltd.15,959$66.4K0.00%+15,959New
WestHill Financial Advisors, Inc.17,082$72.8K0.01%00.0%Unchanged
Twinbeech Capital LP17,600$75.0K0.01%+17,600New
Forefront Analytics, LLC18,699$79.7K0.07%+590+3.3%Added
Sanctuary Advisors, LLC19,140$81.5K0.00%−15,494−44.7%Reduced
Advisor Group Holdings, Inc.19,410$82.7K0.00%+2,700+16.2%Added
Jain Global LLC21,212$90.4K0.00%−12,440−37.0%Reduced
State of Wyoming21,511$91.6K0.01%+21,511New
Invesco Ltd.21,976$93.6K0.00%−450−2.0%Reduced
Mariner, LLC22,180$94.5K0.00%+11,930+116.4%Added
Ethos Financial Group, LLC23,697$100.9K0.01%00.0%Unchanged
Jefferies Financial Group Inc.23,764$101.2K0.00%−29,150−55.1%Reduced
Simplex Trading, LLC24,051$102.5K0.00%+24,051New
JPMorgan Chase & Co24,363$103.8K0.00%+8,211+50.8%Added
Tower Research Capital LLC (TRC)24,794$105.6K0.00%+24,791+826,366.7%Added
HB Wealth Management, LLC25,000$106.5K0.00%+25,000New
Mangrove Partners26,265$111.9K0.01%+26,265New
Engineers Gate Manager LP26,539$113.1K0.00%+26,539New
JustInvest LLC26,765$114.0K0.00%−174−0.6%Reduced
Truvestments Capital LLC27,428$116.8K0.02%+10,327+60.4%Added
China Universal Asset Management Co., Ltd.27,609$117.6K0.01%+27,609New
Cambria Investment Management, L.P.31,332$133.5K0.01%+31,332New
Empowered Funds, LLC31,332$133.5K0.00%+31,332New
Lighthouse Investment Partners, LLC32,040$136.5K0.00%+32,040New
Private Advisor Group, LLC44,002$187.4K0.00%00.0%Unchanged
Baader Bank INC45,000$191.7K0.02%+45,000New
Formidable Asset Management, LLC45,763$194.9K0.03%−72,574−61.3%Reduced
Toroso Investments, LLC45,763$194.9K0.00%−72,574−61.3%Reduced
XTX Topco Ltd47,991$204.4K0.01%+18,705+63.9%Added
Susquehanna Portfolio Strategies, LLC48,012$204.5K0.00%00.0%Unchanged
Seven Fleet Capital Management LP48,898$208.3K0.14%+48,898New
Squarepoint Ops LLC49,897$212.6K0.00%+2,169+4.5%Added
Hudson Bay Capital Management LP50,990$217.2K0.00%+50,990New
Timothy G. Youngquist 2020 Irrevocable Trust51,155$217.9K0.19%+51,155New
SG Americas Securities, LLC53,109$226.0K0.00%+53,109New
Merit Financial Group, LLC53,243$226.8K0.00%00.0%Unchanged
Congress Park Capital LLC58,922$251.0K0.07%−45,000−43.3%Reduced
Skopos Labs, Inc.61,474$257.6K0.01%+61,474New
Virtus Investment Advisers, Inc.63,491$270.5K0.07%+63,491New
Miller Financial Services LLC68,000$289.7K0.34%+1,000+1.5%Added
Charles Schwab Investment Management Inc68,687$292.6K0.00%−19,883−22.4%Reduced
HRT Financial LP71,867$306.0K0.00%+71,867New
Velan Capital Investment Management LP80,000$340.8K0.20%00.0%Unchanged
Gsa Capital Partners LLP81,886$349.0K0.03%−454,088−84.7%Reduced
Omers Administration Corp87,800$374.0K0.00%+87,800New
Citigroup Inc96,326$410.3K0.00%+88,570+1,142.0%Added
Profund Advisors LLC98,633$420.2K0.01%+98,633New
NLB Skladi, upravljanje premozenja, d.o.o.100,000$426.0K0.02%+100,000New
Aspire Growth Partners LLC102,254$435.6K0.30%00.0%Unchanged
Canada Pension Plan Investment Board104,200$443.9K0.00%+104,200New
LPL Financial LLC113,440$483.3K0.00%+26,787+30.9%Added
SEI Investments Co124,124$528.8K0.00%+124,124New
HighVista Strategies LLC193,941$826.2K0.21%−63,207−24.6%Reduced
EAM Investors, LLC203,823$868.3K0.10%+203,823New
Prelude Capital Management, LLC206,526$879.8K0.06%00.0%Unchanged
Ameriprise Financial Inc229,599$989.0K0.00%+71,270+45.0%Added
Rafferty Asset Management, LLC273,584$1.17M0.00%+273,584New
Millennium Management LLC289,653$1.23M0.00%−1,097,210−79.1%Reduced
Raymond James Financial Inc316,971$1.35M0.00%+23,411+8.0%Added
Bank of New York Mellon Corp328,248$1.40M0.00%+75,589+29.9%Added
Two Sigma Advisers, LP335,524$1.43M0.00%+295,524+738.8%Added
Barclays PLC336,525$1.43M0.00%+335,035+22,485.6%Added
Citadel Advisors LLC342,304$1.46M0.00%−1,458,131−81.0%Reduced
UBS Group AG370,739$1.58M0.00%+340,571+1,128.9%Added
Schulhoff & Co Inc374,850$1.60M0.67%+374,850New
Silverarc Capital Management, LLC385,974$1.64M0.24%+385,974New
Morgan Stanley401,191$1.71M0.00%+81,903+25.7%Added
Northern Trust Corp415,178$1.77M0.00%+25,493+6.5%Added
First Trust Advisors LP423,168$1.80M0.00%+21,277+5.3%Added
Assenagon Asset Management S.A.592,696$2.52M0.00%−137,271−18.8%Reduced
Jane Street Group, LLC607,218$2.59M0.00%+205,851+51.3%Added
Elmind Capital, LP700,000$2.98M0.88%+700,000New
Exome Asset Management LLC745,305$3.17M1.57%00.0%Unchanged
Acadian Asset Management LLC856,056$3.64M0.01%+202,331+31.0%Added
Bank of America Corp876,305$3.73M0.00%−128,923−12.8%Reduced
Boothbay Fund Management, LLC894,663$3.81M0.10%−342,394−27.7%Reduced
Susquehanna International Group, LLP981,598$4.18M0.01%+714,113+267.0%Added
StemPoint Capital LP1,036,311$4.41M0.76%+1,036,311New
Qube Research & Technologies Ltd1,061,128$4.52M0.01%+938,628+766.2%Added
Marshall Wace, LLP1,156,936$4.93M0.00%+51,943+4.7%Added