Castle Biosciences Inc
CSTL- Exchange
- Nasdaq
- Industry
- Services-Medical Laboratories
- SEC CIK
- 0001447362
In the last 90 days, Castle Biosciences Inc insiders filed 0 open-market purchases and 20 sales; 176 institutions reported holding it in 13F filings for Q2 2026, worth $653.8M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Castle Biosciences Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 195
- +26 vs. Q3 2025
- Shares held
- 27.3M
- +724.4K (+2.7%) vs. Q3 2025
- Total value
- $1.06B
- +$455.1M (+75.0%) vs. Q3 2025
- New holders
- 43
- 64 more added
- Sold out
- 17
- 69 more reduced
4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CSTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 176 | $653.8M |
| Q1 2026 | 186 | $677.8M |
| Q4 2025 | 195 | $1.06B |
| Q3 2025 | 173 | $608.3M |
| Q2 2025 | 152 | $541.8M |
| Q1 2025 | 180 | $516.3M |
| Q4 2024 | 197 | $706.4M |
| Q3 2024 | 185 | $736.9M |
| Q2 2024 | 159 | $549.4M |
| Q1 2024 | 151 | $553.2M |
| Q4 2023 | 153 | $515.4M |
| Q3 2023 | 135 | $391.0M |
| Q2 2023 | 130 | $316.6M |
| Q1 2023 | 148 | $501.9M |
| Q4 2022 | 153 | $522.0M |
| Q3 2022 | 157 | $569.8M |
| Q2 2022 | 146 | $495.0M |
| Q1 2022 | 160 | $1.02B |
| Q4 2021 | 159 | $918.6M |
| Q3 2021 | 188 | $1.42B |
| Q2 2021 | 182 | $1.52B |
| Q1 2021 | 175 | $1.46B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Castle Biosciences Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Parallel Advisors, LLC | 13,986 | $544.1K | 0.01% | −3,800−21.4% | Reduced |
| Los Angeles Capital Management LLC | 23,631 | $572.1K | 0.00% | −490−2.0% | Reduced |
| Janus Henderson Group PLC | 15,037 | $585.0K | 0.00% | +5,900+64.6% | Added |
| MetLife Investment Management | 15,881 | $617.8K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 16,141 | $627.9K | 0.00% | −135−0.8% | Reduced |
| First Bank & Trust | 16,706 | $649.9K | 0.11% | −3,093−15.6% | Reduced |
| Verition Fund Management LLC | 16,811 | $653.9K | 0.00% | +1,169+7.5% | Added |
| Quest Partners LLC | 17,116 | $665.8K | 0.04% | +2,572+17.7% | Added |
| SummitTX Capital, L.P. | 17,410 | $677.2K | 0.02% | −27,590−61.3% | Reduced |
| Algert Global LLC | 18,978 | $738.2K | 0.01% | −38,917−67.2% | Reduced |
| HSBC Holdings PLC | 19,486 | $760.3K | 0.00% | −13,747−41.4% | Reduced |
| SG Americas Securities, LLC | 21,262 | $827.0K | 0.00% | +8,201+62.8% | Added |
| Schonfeld Strategic Advisors LLC | 21,476 | $835.4K | 0.00% | −66,215−75.5% | Reduced |
| Fox Run Management, L.L.C. | 21,884 | $851.3K | 0.13% | +8,064+58.4% | Added |
| XTX Topco Ltd | 22,125 | $860.7K | 0.02% | +22,125 | New |
| Deutsche Bank AG | 22,384 | $870.7K | 0.00% | +5,742+34.5% | Added |
| Caxton Associates LLP | 22,464 | $873.9K | 0.02% | +22,464 | New |
| Engineers Gate Manager LP | 22,949 | $892.7K | 0.01% | −23,557−50.7% | Reduced |
| Truist Financial Corp | 23,628 | $919.1K | 0.00% | +257+1.1% | Added |
| Alliancebernstein L.P. | 25,270 | $983.0K | 0.00% | −8,100−24.3% | Reduced |
| California State Teachers Retirement System | 27,725 | $1.08M | 0.00% | +3,103+12.6% | Added |
| Perkins Capital Management Inc | 28,045 | $1.09M | 0.87% | −100−0.4% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 29,357 | $1.14M | 0.00% | −526−1.8% | Reduced |
| Legal & General Group Plc | 29,735 | $1.16M | 0.00% | −5,173−14.8% | Reduced |
| Two Sigma Advisers, LP | 29,899 | $1.16M | 0.00% | +19,999+202.0% | Added |
| Citigroup Inc | 32,422 | $1.26M | 0.00% | +28,172+662.9% | Added |
| Price T Rowe Associates Inc | 34,138 | $1.33M | 0.00% | +1,545+4.7% | Added |
| Wells Fargo & Company | 34,212 | $1.33M | 0.00% | +10,233+42.7% | Added |
| Ameriprise Financial Inc | 35,368 | $1.38M | 0.00% | −220,865−86.2% | Reduced |
| Advisor Group Holdings, Inc. | 36,404 | $1.42M | 0.00% | +35,996+8,822.5% | Added |
| Mackenzie Financial Corp | 37,317 | $1.46M | 0.00% | +13,113+54.2% | Added |
| Rhumbline Advisers | 38,468 | $1.50M | 0.00% | −5,290−12.1% | Reduced |
| SEI Investments Co | 39,727 | $1.55M | 0.00% | +12,956+48.4% | Added |
| FMR LLC | 42,286 | $1.64M | 0.00% | +13,744+48.2% | Added |
| Panagora Asset Management Inc | 45,995 | $1.79M | 0.01% | +24,597+114.9% | Added |
| HRT Financial LP | 47,654 | $1.85M | 0.01% | +415+0.9% | Added |
| Squarepoint Ops LLC | 55,118 | $2.14M | 0.00% | +55,118 | New |
| Swiss National Bank | 57,300 | $2.23M | 0.00% | +1,300+2.3% | Added |
| Envestnet Asset Management Inc | 61,966 | $2.41M | 0.00% | −4,962−7.4% | Reduced |
| AQR Capital Management LLC | 63,881 | $2.48M | 0.00% | +13,039+25.6% | Added |
| Trexquant Investment LP | 64,605 | $2.51M | 0.02% | −113,837−63.8% | Reduced |
| UBS Asset Management Americas Inc | 69,628 | $2.71M | 0.00% | +12,168+21.2% | Added |
| Barclays PLC | 72,149 | $2.81M | 0.00% | −919−1.3% | Reduced |
| EAM Investors, LLC | 74,138 | $2.88M | 0.32% | +74,138 | New |
| Brinker Capital Investments, LLC | 74,653 | $2.90M | 0.02% | −1,691−2.2% | Reduced |
| American Century Companies Inc | 77,768 | $3.03M | 0.00% | −4,744−5.7% | Reduced |
| Birchview Capital, LP | 80,600 | $3.14M | 1.84% | −30,000−27.1% | Reduced |
| Franklin Resources Inc | 80,603 | $3.14M | 0.00% | −19,184−19.2% | Reduced |
| Two Sigma Investments, LP | 84,066 | $3.27M | 0.00% | +58,366+227.1% | Added |
| Bank of New York Mellon Corp | 86,984 | $3.38M | 0.00% | −7,032−7.5% | Reduced |
| JPMorgan Chase & Co | 90,032 | $3.50M | 0.00% | +62,254+224.1% | Added |
| Point72 Asset Management, L.P. | 119,458 | $4.65M | 0.01% | −217,500−64.5% | Reduced |
| Empowered Funds, LLC | 121,920 | $4.74M | 0.08% | +23,740+24.2% | Added |
| Invesco Ltd. | 135,461 | $5.27M | 0.00% | +79,621+142.6% | Added |
| UBS Group AG | 141,873 | $5.52M | 0.00% | −149,489−51.3% | Reduced |
| BNP Paribas Arbitrage, SA | 150,011 | $5.84M | 0.00% | +10,097+7.2% | Added |
| Parkman Healthcare Partners LLC | 150,558 | $5.86M | 0.56% | −325,010−68.3% | Reduced |
| Allspring Global Investments Holdings, LLC | 159,171 | $6.13M | 0.01% | +2,658+1.7% | Added |
| D. E. Shaw & Co., Inc. | 159,709 | $6.21M | 0.00% | +67,095+72.4% | Added |
| Tudor Investment Corp Et Al | 167,178 | $6.50M | 0.04% | +81,743+95.7% | Added |
| Jane Street Group, LLC | 168,646 | $6.56M | 0.01% | +145,762+637.0% | Added |
| Braidwell LP | 177,183 | $6.89M | 0.22% | −645,552−78.5% | Reduced |
| Morgan Stanley | 203,577 | $7.92M | 0.00% | −66,054−24.5% | Reduced |
| Silvercrest Asset Management Group LLC | 205,002 | $7.97M | 0.05% | −162,886−44.3% | Reduced |
| Wellington Management Group LLP | 218,560 | $8.50M | 0.00% | +218,560 | New |
| New York State Common Retirement Fund | 233,046 | $9.07M | 0.01% | +3,000+1.3% | Added |
| Qube Research & Technologies Ltd | 235,518 | $9.16M | 0.01% | +14,557+6.6% | Added |
| Charles Schwab Investment Management Inc | 242,535 | $9.43M | 0.00% | +4,381+1.8% | Added |
| Bridgeway Capital Management, LLC | 246,920 | $9.61M | 0.20% | +69,740+39.4% | Added |
| Advisors Capital Management, LLC | 250,677 | $9.75M | 0.11% | −3,523−1.4% | Reduced |
| Northern Trust Corp | 262,243 | $10.2M | 0.00% | −20,024−7.1% | Reduced |
| Bank of America Corp | 263,019 | $10.2M | 0.00% | −52,351−16.6% | Reduced |
| Kornitzer Capital Management Inc | 267,733 | $10.4M | 0.22% | −10,581−3.8% | Reduced |
| Goldman Sachs Group Inc | 287,235 | $11.2M | 0.00% | −57,864−16.8% | Reduced |
| Eventide Asset Management, LLC | 305,000 | $11.9M | 0.19% | +305,000 | New |
| Millennium Management LLC | 308,914 | $12.0M | 0.01% | −266,175−46.3% | Reduced |
| Citadel Advisors LLC | 366,356 | $14.3M | 0.01% | +115,441+46.0% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 388,491 | $15.1M | 0.04% | +52,600+15.7% | Added |
| Acadian Asset Management LLC | 390,406 | $15.2M | 0.02% | −61,246−13.6% | Reduced |
| Renaissance Technologies LLC | 493,100 | $19.2M | 0.03% | −69,500−12.4% | Reduced |
| Schroder Investment Management Group | 492,161 | $19.3M | 0.01% | −2,789−0.6% | Reduced |
| Nuveen, LLC | 524,681 | $20.4M | 0.01% | −432,400−45.2% | Reduced |
| Wasatch Advisors Inc | 537,241 | $20.9M | 0.12% | −131,879−19.7% | Reduced |
| Palisade Capital Management LLC | 567,777 | $22.1M | 0.65% | −70,879−11.1% | Reduced |
| Allianz Asset Management GmbH | 622,299 | $24.2M | 0.03% | −26,052−4.0% | Reduced |
| AIGH Capital Management LLC | 624,719 | $24.3M | 7.18% | −82,568−11.7% | Reduced |
| Geode Capital Management, LLC | 714,913 | $27.8M | 0.00% | +16,303+2.3% | Added |
| State Street Corp | 736,454 | $28.6M | 0.00% | +12,374+1.7% | Added |
| Summit Partners Public Asset Management, LLC | 1,058,725 | $41.2M | 1.16% | +658,725+164.7% | Added |
| Dimensional Fund Advisors LP | 1,143,799 | $44.5M | 0.01% | −330,290−22.4% | Reduced |
| Portolan Capital Management, LLC | 1,729,463 | $67.3M | 3.60% | +214,352+14.1% | Added |
| Principal Financial Group Inc | 1,807,644 | $70.3M | 0.04% | +13,289+0.7% | Added |
| RTW Investments, LP | 2,115,237 | $82.3M | 0.82% | +2,115,237 | New |
| Vanguard Group Inc | 2,199,829 | $85.6M | 0.00% | +27,511+1.3% | Added |
| BlackRock, Inc. | 3,105,246 | $120.8M | 0.00% | −84,650−2.7% | Reduced |
| Summit Wealth Group LLC | 0 | $0 | 0.00% | −122,494−100.0% | Sold out |
| Tritonpoint Wealth, LLC | 0 | $0 | 0.00% | −40,777−100.0% | Sold out |
| Healthcare of Ontario Pension Plan Trust Fund | 0 | $0 | 0.00% | −35,800−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −29,310−100.0% | Sold out |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −26,996−100.0% | Sold out |