Castle Biosciences Inc
CSTL- Exchange
- Nasdaq
- Industry
- Services-Medical Laboratories
- SEC CIK
- 0001447362
In the last 90 days, Castle Biosciences Inc insiders filed 0 open-market purchases and 20 sales; 176 institutions reported holding it in 13F filings for Q2 2026, worth $653.8M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Castle Biosciences Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 195
- +26 vs. Q3 2025
- Shares held
- 27.3M
- +724.4K (+2.7%) vs. Q3 2025
- Total value
- $1.06B
- +$455.1M (+75.0%) vs. Q3 2025
- New holders
- 43
- 64 more added
- Sold out
- 17
- 69 more reduced
4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CSTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 176 | $653.8M |
| Q1 2026 | 186 | $677.8M |
| Q4 2025 | 195 | $1.06B |
| Q3 2025 | 173 | $608.3M |
| Q2 2025 | 152 | $541.8M |
| Q1 2025 | 180 | $516.3M |
| Q4 2024 | 197 | $706.4M |
| Q3 2024 | 185 | $736.9M |
| Q2 2024 | 159 | $549.4M |
| Q1 2024 | 151 | $553.2M |
| Q4 2023 | 153 | $515.4M |
| Q3 2023 | 135 | $391.0M |
| Q2 2023 | 130 | $316.6M |
| Q1 2023 | 148 | $501.9M |
| Q4 2022 | 153 | $522.0M |
| Q3 2022 | 157 | $569.8M |
| Q2 2022 | 146 | $495.0M |
| Q1 2022 | 160 | $1.02B |
| Q4 2021 | 159 | $918.6M |
| Q3 2021 | 188 | $1.42B |
| Q2 2021 | 182 | $1.52B |
| Q1 2021 | 175 | $1.46B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Castle Biosciences Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 3,105,246 | $120.8M | 0.00% | −84,650−2.7% | Reduced |
| Vanguard Group Inc | 2,199,829 | $85.6M | 0.00% | +27,511+1.3% | Added |
| RTW Investments, LP | 2,115,237 | $82.3M | 0.82% | +2,115,237 | New |
| Principal Financial Group Inc | 1,807,644 | $70.3M | 0.04% | +13,289+0.7% | Added |
| Portolan Capital Management, LLC | 1,729,463 | $67.3M | 3.60% | +214,352+14.1% | Added |
| Dimensional Fund Advisors LP | 1,143,799 | $44.5M | 0.01% | −330,290−22.4% | Reduced |
| Summit Partners Public Asset Management, LLC | 1,058,725 | $41.2M | 1.16% | +658,725+164.7% | Added |
| State Street Corp | 736,454 | $28.6M | 0.00% | +12,374+1.7% | Added |
| Geode Capital Management, LLC | 714,913 | $27.8M | 0.00% | +16,303+2.3% | Added |
| AIGH Capital Management LLC | 624,719 | $24.3M | 7.18% | −82,568−11.7% | Reduced |
| Allianz Asset Management GmbH | 622,299 | $24.2M | 0.03% | −26,052−4.0% | Reduced |
| Palisade Capital Management LLC | 567,777 | $22.1M | 0.65% | −70,879−11.1% | Reduced |
| Wasatch Advisors Inc | 537,241 | $20.9M | 0.12% | −131,879−19.7% | Reduced |
| Nuveen, LLC | 524,681 | $20.4M | 0.01% | −432,400−45.2% | Reduced |
| Schroder Investment Management Group | 492,161 | $19.3M | 0.01% | −2,789−0.6% | Reduced |
| Renaissance Technologies LLC | 493,100 | $19.2M | 0.03% | −69,500−12.4% | Reduced |
| Acadian Asset Management LLC | 390,406 | $15.2M | 0.02% | −61,246−13.6% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 388,491 | $15.1M | 0.04% | +52,600+15.7% | Added |
| Citadel Advisors LLC | 366,356 | $14.3M | 0.01% | +115,441+46.0% | Added |
| Millennium Management LLC | 308,914 | $12.0M | 0.01% | −266,175−46.3% | Reduced |
| Eventide Asset Management, LLC | 305,000 | $11.9M | 0.19% | +305,000 | New |
| Goldman Sachs Group Inc | 287,235 | $11.2M | 0.00% | −57,864−16.8% | Reduced |
| Kornitzer Capital Management Inc | 267,733 | $10.4M | 0.22% | −10,581−3.8% | Reduced |
| Bank of America Corp | 263,019 | $10.2M | 0.00% | −52,351−16.6% | Reduced |
| Northern Trust Corp | 262,243 | $10.2M | 0.00% | −20,024−7.1% | Reduced |
| Advisors Capital Management, LLC | 250,677 | $9.75M | 0.11% | −3,523−1.4% | Reduced |
| Bridgeway Capital Management, LLC | 246,920 | $9.61M | 0.20% | +69,740+39.4% | Added |
| Charles Schwab Investment Management Inc | 242,535 | $9.43M | 0.00% | +4,381+1.8% | Added |
| Qube Research & Technologies Ltd | 235,518 | $9.16M | 0.01% | +14,557+6.6% | Added |
| New York State Common Retirement Fund | 233,046 | $9.07M | 0.01% | +3,000+1.3% | Added |
| Wellington Management Group LLP | 218,560 | $8.50M | 0.00% | +218,560 | New |
| Silvercrest Asset Management Group LLC | 205,002 | $7.97M | 0.05% | −162,886−44.3% | Reduced |
| Morgan Stanley | 203,577 | $7.92M | 0.00% | −66,054−24.5% | Reduced |
| Braidwell LP | 177,183 | $6.89M | 0.22% | −645,552−78.5% | Reduced |
| Jane Street Group, LLC | 168,646 | $6.56M | 0.01% | +145,762+637.0% | Added |
| Tudor Investment Corp Et Al | 167,178 | $6.50M | 0.04% | +81,743+95.7% | Added |
| D. E. Shaw & Co., Inc. | 159,709 | $6.21M | 0.00% | +67,095+72.4% | Added |
| Allspring Global Investments Holdings, LLC | 159,171 | $6.13M | 0.01% | +2,658+1.7% | Added |
| Parkman Healthcare Partners LLC | 150,558 | $5.86M | 0.56% | −325,010−68.3% | Reduced |
| BNP Paribas Arbitrage, SA | 150,011 | $5.84M | 0.00% | +10,097+7.2% | Added |
| UBS Group AG | 141,873 | $5.52M | 0.00% | −149,489−51.3% | Reduced |
| Invesco Ltd. | 135,461 | $5.27M | 0.00% | +79,621+142.6% | Added |
| Empowered Funds, LLC | 121,920 | $4.74M | 0.08% | +23,740+24.2% | Added |
| Point72 Asset Management, L.P. | 119,458 | $4.65M | 0.01% | −217,500−64.5% | Reduced |
| JPMorgan Chase & Co | 90,032 | $3.50M | 0.00% | +62,254+224.1% | Added |
| Bank of New York Mellon Corp | 86,984 | $3.38M | 0.00% | −7,032−7.5% | Reduced |
| Two Sigma Investments, LP | 84,066 | $3.27M | 0.00% | +58,366+227.1% | Added |
| Franklin Resources Inc | 80,603 | $3.14M | 0.00% | −19,184−19.2% | Reduced |
| Birchview Capital, LP | 80,600 | $3.14M | 1.84% | −30,000−27.1% | Reduced |
| American Century Companies Inc | 77,768 | $3.03M | 0.00% | −4,744−5.7% | Reduced |
| Brinker Capital Investments, LLC | 74,653 | $2.90M | 0.02% | −1,691−2.2% | Reduced |
| EAM Investors, LLC | 74,138 | $2.88M | 0.32% | +74,138 | New |
| Barclays PLC | 72,149 | $2.81M | 0.00% | −919−1.3% | Reduced |
| UBS Asset Management Americas Inc | 69,628 | $2.71M | 0.00% | +12,168+21.2% | Added |
| Trexquant Investment LP | 64,605 | $2.51M | 0.02% | −113,837−63.8% | Reduced |
| AQR Capital Management LLC | 63,881 | $2.48M | 0.00% | +13,039+25.6% | Added |
| Envestnet Asset Management Inc | 61,966 | $2.41M | 0.00% | −4,962−7.4% | Reduced |
| Swiss National Bank | 57,300 | $2.23M | 0.00% | +1,300+2.3% | Added |
| Squarepoint Ops LLC | 55,118 | $2.14M | 0.00% | +55,118 | New |
| HRT Financial LP | 47,654 | $1.85M | 0.01% | +415+0.9% | Added |
| Panagora Asset Management Inc | 45,995 | $1.79M | 0.01% | +24,597+114.9% | Added |
| FMR LLC | 42,286 | $1.64M | 0.00% | +13,744+48.2% | Added |
| SEI Investments Co | 39,727 | $1.55M | 0.00% | +12,956+48.4% | Added |
| Rhumbline Advisers | 38,468 | $1.50M | 0.00% | −5,290−12.1% | Reduced |
| Mackenzie Financial Corp | 37,317 | $1.46M | 0.00% | +13,113+54.2% | Added |
| Advisor Group Holdings, Inc. | 36,404 | $1.42M | 0.00% | +35,996+8,822.5% | Added |
| Ameriprise Financial Inc | 35,368 | $1.38M | 0.00% | −220,865−86.2% | Reduced |
| Wells Fargo & Company | 34,212 | $1.33M | 0.00% | +10,233+42.7% | Added |
| Price T Rowe Associates Inc | 34,138 | $1.33M | 0.00% | +1,545+4.7% | Added |
| Citigroup Inc | 32,422 | $1.26M | 0.00% | +28,172+662.9% | Added |
| Two Sigma Advisers, LP | 29,899 | $1.16M | 0.00% | +19,999+202.0% | Added |
| Legal & General Group Plc | 29,735 | $1.16M | 0.00% | −5,173−14.8% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 29,357 | $1.14M | 0.00% | −526−1.8% | Reduced |
| Perkins Capital Management Inc | 28,045 | $1.09M | 0.87% | −100−0.4% | Reduced |
| California State Teachers Retirement System | 27,725 | $1.08M | 0.00% | +3,103+12.6% | Added |
| Alliancebernstein L.P. | 25,270 | $983.0K | 0.00% | −8,100−24.3% | Reduced |
| Truist Financial Corp | 23,628 | $919.1K | 0.00% | +257+1.1% | Added |
| Engineers Gate Manager LP | 22,949 | $892.7K | 0.01% | −23,557−50.7% | Reduced |
| Caxton Associates LLP | 22,464 | $873.9K | 0.02% | +22,464 | New |
| Deutsche Bank AG | 22,384 | $870.7K | 0.00% | +5,742+34.5% | Added |
| XTX Topco Ltd | 22,125 | $860.7K | 0.02% | +22,125 | New |
| Fox Run Management, L.L.C. | 21,884 | $851.3K | 0.13% | +8,064+58.4% | Added |
| Schonfeld Strategic Advisors LLC | 21,476 | $835.4K | 0.00% | −66,215−75.5% | Reduced |
| SG Americas Securities, LLC | 21,262 | $827.0K | 0.00% | +8,201+62.8% | Added |
| HSBC Holdings PLC | 19,486 | $760.3K | 0.00% | −13,747−41.4% | Reduced |
| Algert Global LLC | 18,978 | $738.2K | 0.01% | −38,917−67.2% | Reduced |
| SummitTX Capital, L.P. | 17,410 | $677.2K | 0.02% | −27,590−61.3% | Reduced |
| Quest Partners LLC | 17,116 | $665.8K | 0.04% | +2,572+17.7% | Added |
| Verition Fund Management LLC | 16,811 | $653.9K | 0.00% | +1,169+7.5% | Added |
| First Bank & Trust | 16,706 | $649.9K | 0.11% | −3,093−15.6% | Reduced |
| Creative Planning | 16,141 | $627.9K | 0.00% | −135−0.8% | Reduced |
| MetLife Investment Management | 15,881 | $617.8K | 0.00% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 15,037 | $585.0K | 0.00% | +5,900+64.6% | Added |
| Los Angeles Capital Management LLC | 23,631 | $572.1K | 0.00% | −490−2.0% | Reduced |
| Parallel Advisors, LLC | 13,986 | $544.1K | 0.01% | −3,800−21.4% | Reduced |
| Oak Harvest Investment Services | 13,485 | $524.6K | 0.06% | −3,398−20.1% | Reduced |
| Harbor Capital Advisors, Inc. | 13,432 | $523.0K | 0.04% | +261+2.0% | Added |
| Y-Intercept (Hong Kong) Ltd | 13,246 | $515.3K | 0.01% | +13,246 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 13,223 | $514.4K | 0.00% | −50−0.4% | Reduced |
| Counterpoint Mutual Funds LLC | 12,952 | $503.8K | 0.04% | +12,952 | New |