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Castle Biosciences Inc

CSTL
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001447362

In the last 90 days, Castle Biosciences Inc insiders filed 0 open-market purchases and 20 sales; 176 institutions reported holding it in 13F filings for Q2 2026, worth $653.8M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Castle Biosciences Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
173
+22 vs. Q2 2025
Shares held
26.6M
+114.3K (+0.4%) vs. Q2 2025
Total value
$608.3M
+$66.6M (+12.3%) vs. Q2 2025
New holders
37
62 more added
Sold out
15
53 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CSTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 173 institutions
Q1 2021: 175 institutionsQ2 2021: 182 institutionsQ3 2021: 188 institutionsQ4 2021: 159 institutionsQ1 2022: 160 institutionsQ2 2022: 146 institutionsQ3 2022: 157 institutionsQ4 2022: 153 institutionsQ1 2023: 148 institutionsQ2 2023: 130 institutionsQ3 2023: 135 institutionsQ4 2023: 153 institutionsQ1 2024: 151 institutionsQ2 2024: 159 institutionsQ3 2024: 185 institutionsQ4 2024: 197 institutionsQ1 2025: 180 institutionsQ2 2025: 152 institutionsQ3 2025: 173 institutionsQ4 2025: 195 institutionsQ1 2026: 186 institutionsQ2 2026: 176 institutions
Value heldQ3 2025: $608.3M
Q1 2021: $1.46BQ2 2021: $1.52BQ3 2021: $1.42BQ4 2021: $918.6MQ1 2022: $1.02BQ2 2022: $495.0MQ3 2022: $569.8MQ4 2022: $522.0MQ1 2023: $501.9MQ2 2023: $316.6MQ3 2023: $391.0MQ4 2023: $515.4MQ1 2024: $553.2MQ2 2024: $549.4MQ3 2024: $736.9MQ4 2024: $706.4MQ1 2025: $516.3MQ2 2025: $541.8MQ3 2025: $608.3MQ4 2025: $1.06BQ1 2026: $677.8MQ2 2026: $653.8M
Institutions holding CSTL and their total value by quarter
QuarterHoldersValue
Q2 2026176$653.8M
Q1 2026186$677.8M
Q4 2025195$1.06B
Q3 2025173$608.3M
Q2 2025152$541.8M
Q1 2025180$516.3M
Q4 2024197$706.4M
Q3 2024185$736.9M
Q2 2024159$549.4M
Q1 2024151$553.2M
Q4 2023153$515.4M
Q3 2023135$391.0M
Q2 2023130$316.6M
Q1 2023148$501.9M
Q4 2022153$522.0M
Q3 2022157$569.8M
Q2 2022146$495.0M
Q1 2022160$1.02B
Q4 2021159$918.6M
Q3 2021188$1.42B
Q2 2021182$1.52B
Q1 2021175$1.46B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Castle Biosciences Inc; share changes are against Q2 2025.

Institutions holding CSTL in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.3,189,896$72.6M0.00%+35,217+1.1%Added
Vanguard Group Inc2,172,318$49.5M0.00%+2,290+0.1%Added
Principal Financial Group Inc1,794,355$40.9M0.02%−4,619−0.3%Reduced
Portolan Capital Management, LLC1,515,111$34.5M1.87%+25,539+1.7%Added
Dimensional Fund Advisors LP1,474,089$33.6M0.01%+96,084+7.0%Added
Nuveen, LLC957,081$21.8M0.01%−116,026−10.8%Reduced
Braidwell LP822,735$18.7M0.56%00.0%Unchanged
State Street Corp724,080$16.5M0.00%+16,393+2.3%Added
AIGH Capital Management LLC707,287$16.1M5.64%+707,287New
Geode Capital Management, LLC698,610$15.9M0.00%+8,684+1.3%Added
Wasatch Advisors Inc669,120$15.2M0.08%−380,653−36.3%Reduced
Allianz Asset Management GmbH648,351$14.8M0.02%−65,391−9.2%Reduced
Palisade Capital Management LLC638,656$14.5M0.40%+63,540+11.0%Added
Millennium Management LLC575,089$13.1M0.01%+146,692+34.2%Added
Renaissance Technologies LLC562,600$12.8M0.02%−107,900−16.1%Reduced
Schroder Investment Management Group494,950$11.1M0.01%−153,622−23.7%Reduced
Parkman Healthcare Partners LLC475,568$10.8M1.19%+123,306+35.0%Added
Acadian Asset Management LLC451,652$10.3M0.02%−92,598−17.0%Reduced
Summit Partners Public Asset Management, LLC400,000$9.11M0.30%+400,000New
Silvercrest Asset Management Group LLC367,888$8.38M0.06%+87,929+31.4%Added
Goldman Sachs Group Inc345,099$7.86M0.00%+71,656+26.2%Added
Point72 Asset Management, L.P.336,958$7.67M0.02%+336,958New
Connor, Clark & Lunn Investment Management Ltd.335,891$7.65M0.02%+209,460+165.7%Added
Bank of America Corp315,370$7.18M0.00%−67,375−17.6%Reduced
UBS Group AG291,362$6.63M0.00%−72,486−19.9%Reduced
Northern Trust Corp282,267$6.43M0.00%+2,442+0.9%Added
Kornitzer Capital Management Inc278,314$6.34M0.13%00.0%Unchanged
Morgan Stanley269,631$6.14M0.00%+102,043+60.9%Added
Ameriprise Financial Inc256,233$5.83M0.00%−116,234−31.2%Reduced
Advisors Capital Management, LLC254,200$5.79M0.07%+8,333+3.4%Added
Citadel Advisors LLC250,915$5.71M0.00%−637,600−71.8%Reduced
Charles Schwab Investment Management Inc238,154$5.42M0.00%+3,139+1.3%Added
New York State Common Retirement Fund230,046$5.24M0.01%+14,216+6.6%Added
Qube Research & Technologies Ltd220,961$5.03M0.01%+28,408+14.8%Added
Summit Wealth Group LLC122,494$4.51M0.62%+122,494New
Trexquant Investment LP178,442$4.06M0.04%−139,630−43.9%Reduced
Bridgeway Capital Management, LLC177,180$4.03M0.09%+136,430+334.8%Added
Allspring Global Investments Holdings, LLC156,513$3.56M0.01%−4,662−2.9%Reduced
BNP Paribas Arbitrage, SA139,914$3.19M0.00%+40,621+40.9%Added
Birchview Capital, LP110,600$2.52M1.90%00.0%Unchanged
Franklin Resources Inc99,787$2.27M0.00%+540+0.5%Added
Empowered Funds, LLC98,180$2.24M0.02%+57,430+140.9%Added
Bank of New York Mellon Corp94,016$2.14M0.00%+4,133+4.6%Added
D. E. Shaw & Co., Inc.92,614$2.11M0.00%−55,576−37.5%Reduced
Schonfeld Strategic Advisors LLC87,691$2.00M0.01%+19,765+29.1%Added
Tudor Investment Corp Et Al85,435$1.95M0.01%+8,981+11.7%Added
American Century Companies Inc82,512$1.88M0.00%+17,240+26.4%Added
Brinker Capital Investments, LLC76,344$1.74M0.01%−188−0.2%Reduced
Barclays PLC73,068$1.66M0.00%−36,675−33.4%Reduced
Envestnet Asset Management Inc66,928$1.52M0.00%−3,550−5.0%Reduced
Algert Global LLC57,895$1.32M0.02%−127,286−68.7%Reduced
UBS Asset Management Americas Inc57,460$1.31M0.00%−45,282−44.1%Reduced
Swiss National Bank56,000$1.28M0.00%+1,700+3.1%Added
Invesco Ltd.55,840$1.27M0.00%+15,411+38.1%Added
AQR Capital Management LLC50,842$1.16M0.00%+1,612+3.3%Added
Cubist Systematic Strategies, LLC50,304$1.15M0.02%+50,304New
HRT Financial LP47,239$1.07M0.00%+28,413+150.9%Added
Engineers Gate Manager LP46,506$1.06M0.01%−20,746−30.8%Reduced
SummitTX Capital, L.P.45,000$1.02M0.04%+45,000New
Rhumbline Advisers43,758$996.4K0.00%−1,639−3.6%Reduced
Tritonpoint Wealth, LLC40,777$928.5K0.08%00.0%Unchanged
Healthcare of Ontario Pension Plan Trust Fund35,800$815.2K0.00%00.0%Unchanged
Legal & General Group Plc34,908$794.9K0.00%00.0%Unchanged
Alliancebernstein L.P.33,370$759.8K0.00%00.0%Unchanged
HSBC Holdings PLC33,233$749.0K0.00%−785−2.3%Reduced
Price T Rowe Associates Inc32,593$743.0K0.00%+6,186+23.4%Added
Universal- Beteiligungs- und Servicegesellschaft mbH29,883$680.4K0.00%−24,727−45.3%Reduced
Dynamic Technology Lab Private Ltd29,310$667.0K0.11%+29,310New
FMR LLC28,542$649.9K0.00%+4,542+18.9%Added
Perkins Capital Management Inc28,145$640.9K0.56%+150+0.5%Added
JPMorgan Chase & Co27,778$632.5K0.00%+1,115+4.2%Added
Campbell & CO Investment Adviser LLC26,996$614.7K0.05%+26,996New
SEI Investments Co26,771$609.6K0.00%−4,359−14.0%Reduced
Two Sigma Investments, LP25,700$585.2K0.00%−2,541−9.0%Reduced
California State Teachers Retirement System24,622$560.6K0.00%+20.0%Added
Susquehanna International Group, LLP24,225$551.6K0.00%−18,628−43.5%Reduced
Mackenzie Financial Corp24,204$551.1K0.00%00.0%Unchanged
Los Angeles Capital Management LLC24,121$549.2K0.00%+24,121New
Wells Fargo & Company23,979$546.0K0.00%+3,679+18.1%Added
Truist Financial Corp23,371$532.2K0.00%−652−2.7%Reduced
Jane Street Group, LLC22,884$521.1K0.00%+22,884New
Panagora Asset Management Inc21,398$487.2K0.00%+21,398New
Graham Capital Management, L.P.21,133$481.2K0.02%−20,650−49.4%Reduced
CWM Advisors, LLC19,887$452.8K0.04%+770+4.0%Added
First Bank & Trust19,799$450.8K0.08%−152−0.8%Reduced
Brevan Howard Capital Management LP19,128$435.5K0.01%−22,173−53.7%Reduced
Parallel Advisors, LLC17,786$405.0K0.01%−10,107−36.2%Reduced
Oak Harvest Investment Services16,883$384.4K0.04%00.0%Unchanged
Capstone Investment Advisors, LLC16,677$379.7K0.00%+16,677New
Deutsche Bank AG16,642$378.9K0.00%−45,101−73.0%Reduced
Creative Planning16,276$370.6K0.00%+5,165+46.5%Added
MetLife Investment Management15,881$361.6K0.00%00.0%Unchanged
Verition Fund Management LLC15,642$356.2K0.00%−15,897−50.4%Reduced
Quest Partners LLC14,544$331.2K0.02%+12,449+594.2%Added
Fox Run Management, L.L.C.13,820$314.7K0.05%+13,820New
Simon Quick Advisors, LLC13,562$308.8K0.01%00.0%Unchanged
Diversify Wealth Management, LLC11,747$305.3K0.02%−575−4.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.13,273$302.2K0.00%−2,288−14.7%Reduced
Harbor Capital Advisors, Inc.13,171$300.0K0.02%−7,228−35.4%Reduced
SG Americas Securities, LLC13,061$297.0K0.00%+13,061New