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Castle Biosciences Inc

CSTL
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001447362

In the last 90 days, Castle Biosciences Inc insiders filed 0 open-market purchases and 20 sales; 176 institutions reported holding it in 13F filings for Q2 2026, worth $653.8M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Castle Biosciences Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
180
−14 vs. Q4 2024
Shares held
25.9M
−168.1K (−0.6%) vs. Q4 2024
Total value
$516.3M
−$177.7M (−25.6%) vs. Q4 2024
New holders
30
76 more added
Sold out
44
54 more reduced

3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CSTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 180 institutions
Q1 2021: 175 institutionsQ2 2021: 182 institutionsQ3 2021: 188 institutionsQ4 2021: 159 institutionsQ1 2022: 160 institutionsQ2 2022: 146 institutionsQ3 2022: 157 institutionsQ4 2022: 153 institutionsQ1 2023: 148 institutionsQ2 2023: 130 institutionsQ3 2023: 135 institutionsQ4 2023: 153 institutionsQ1 2024: 151 institutionsQ2 2024: 159 institutionsQ3 2024: 185 institutionsQ4 2024: 197 institutionsQ1 2025: 180 institutionsQ2 2025: 152 institutionsQ3 2025: 173 institutionsQ4 2025: 195 institutionsQ1 2026: 186 institutionsQ2 2026: 176 institutions
Value heldQ1 2025: $516.3M
Q1 2021: $1.46BQ2 2021: $1.52BQ3 2021: $1.42BQ4 2021: $918.6MQ1 2022: $1.02BQ2 2022: $495.0MQ3 2022: $569.8MQ4 2022: $522.0MQ1 2023: $501.9MQ2 2023: $316.6MQ3 2023: $391.0MQ4 2023: $515.4MQ1 2024: $553.2MQ2 2024: $549.4MQ3 2024: $736.9MQ4 2024: $706.4MQ1 2025: $516.3MQ2 2025: $541.8MQ3 2025: $608.3MQ4 2025: $1.06BQ1 2026: $677.8MQ2 2026: $653.8M
Institutions holding CSTL and their total value by quarter
QuarterHoldersValue
Q2 2026176$653.8M
Q1 2026186$677.8M
Q4 2025195$1.06B
Q3 2025173$608.3M
Q2 2025152$541.8M
Q1 2025180$516.3M
Q4 2024197$706.4M
Q3 2024185$736.9M
Q2 2024159$549.4M
Q1 2024151$553.2M
Q4 2023153$515.4M
Q3 2023135$391.0M
Q2 2023130$316.6M
Q1 2023148$501.9M
Q4 2022153$522.0M
Q3 2022157$569.8M
Q2 2022146$495.0M
Q1 2022160$1.02B
Q4 2021159$918.6M
Q3 2021188$1.42B
Q2 2021182$1.52B
Q1 2021175$1.46B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Castle Biosciences Inc; share changes are against Q4 2024.

Institutions holding CSTL in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.2,983,540$59.7M0.00%+62,231+2.1%Added
Vanguard Group Inc2,047,565$41.0M0.00%+215,030+11.7%Added
Principal Financial Group Inc1,467,873$29.4M0.02%+32,208+2.2%Added
Portolan Capital Management, LLC1,265,223$25.3M1.93%+488,644+62.9%Added
Dimensional Fund Advisors LP1,200,222$24.0M0.01%+200,756+20.1%Added
Wasatch Advisors Inc998,455$20.0M0.11%−797,633−44.4%Reduced
Wellington Management Group LLP828,528$16.6M0.00%+106,408+14.7%Added
State Street Corp715,028$14.3M0.00%+4,816+0.7%Added
Renaissance Technologies LLC701,200$14.0M0.02%+16,200+2.4%Added
Acadian Asset Management LLC676,066$13.5M0.04%+267,416+65.4%Added
Geode Capital Management, LLC649,853$13.0M0.00%+21,657+3.4%Added
Allianz Asset Management GmbH639,477$12.8M0.02%+317,103+98.4%Added
Schroder Investment Management Group597,089$11.9M0.01%+597,089New
Nuveen, LLC671,811$11.9M0.00%+671,811New
Park West Asset Management LLC556,485$11.1M0.91%+556,485New
Palisade Capital Management LLC489,968$9.81M0.28%−13,474−2.7%Reduced
Bank of America Corp375,380$7.52M0.00%−28,173−7.0%Reduced
Braidwell LP365,247$7.31M0.26%+365,247New
Parkman Healthcare Partners LLC350,551$7.02M0.83%+45,922+15.1%Added
Ameriprise Financial Inc325,697$6.52M0.00%+9,661+3.1%Added
Bellevue Group AG301,103$6.03M0.14%−444,879−59.6%Reduced
Qube Research & Technologies Ltd279,364$5.59M0.01%+61,820+28.4%Added
Kornitzer Capital Management Inc278,314$5.57M0.11%−105,660−27.5%Reduced
Northern Trust Corp273,469$5.47M0.00%−11,118−3.9%Reduced
Citadel Advisors LLC258,382$5.17M0.01%−576,130−69.0%Reduced
Millennium Management LLC254,749$5.10M0.00%−294,060−53.6%Reduced
Trexquant Investment LP248,991$4.98M0.06%+45,420+22.3%Added
Charles Schwab Investment Management Inc242,258$4.85M0.00%−16,608−6.4%Reduced
Cubist Systematic Strategies, LLC237,698$4.76M0.06%+60,161+33.9%Added
Point72 Asset Management, L.P.236,218$4.73M0.01%−310,886−56.8%Reduced
Allspring Global Investments Holdings, LLC217,794$4.36M0.01%+207,761+2,070.8%Added
Morgan Stanley211,793$4.24M0.00%−94,884−30.9%Reduced
Advisors Capital Management, LLC201,687$4.04M0.06%+22,752+12.7%Added
Silvercrest Asset Management Group LLC198,802$3.98M0.03%−1,148−0.6%Reduced
D. E. Shaw & Co., Inc.189,177$3.79M0.00%+98,614+108.9%Added
Connor, Clark & Lunn Investment Management Ltd.176,889$3.54M0.02%+8,176+4.8%Added
Goldman Sachs Group Inc175,325$3.51M0.00%−257,425−59.5%Reduced
Tudor Investment Corp Et Al171,382$3.43M0.03%+101,306+144.6%Added
Shelton Capital Management164,008$3.28M0.08%00.0%Unchanged
New York State Common Retirement Fund163,159$3.27M0.00%−25,942−13.7%Reduced
Algert Global LLC144,311$2.89M0.07%−5,180−3.5%Reduced
Two Sigma Investments, LP139,785$2.80M0.01%+139,785New
AQR Capital Management LLC137,022$2.74M0.00%+115,907+548.9%Added
Franklin Resources Inc99,086$1.98M0.00%+25,449+34.6%Added
Squarepoint Ops LLC97,360$1.95M0.00%+80,043+462.2%Added
Birchview Capital, LP88,404$1.77M1.54%+10,404+13.3%Added
Bank of New York Mellon Corp84,041$1.68M0.00%−418−0.5%Reduced
Brinker Capital Investments, LLC78,409$1.57M0.02%+10,093+14.8%Added
Orion Portfolio Solutions, LLC78,409$1.57M0.02%+10,093+14.8%Added
ExodusPoint Capital Management, LP77,563$1.55M0.02%+66,079+575.4%Added
American Century Companies Inc74,067$1.48M0.00%+4,892+7.1%Added
SEI Investments Co73,059$1.46M0.00%+31,568+76.1%Added
Envestnet Asset Management Inc69,771$1.40M0.00%−3,573−4.9%Reduced
Two Sigma Advisers, LP69,200$1.39M0.00%+57,700+501.7%Added
Graham Capital Management, L.P.68,385$1.37M0.04%+26,709+64.1%Added
UBS Asset Management Americas Inc68,031$1.36M0.00%+2,013+3.0%Added
Gsa Capital Partners LLP67,143$1.34M0.12%−3,658−5.2%Reduced
Deutsche Bank AG65,537$1.31M0.00%−2,130−3.1%Reduced
Citigroup Inc62,701$1.26M0.00%+21,374+51.7%Added
Schonfeld Strategic Advisors LLC59,671$1.19M0.01%+44,371+290.0%Added
Jackson Creek Investment Advisors LLC57,094$1.14M0.36%+57,094New
Swiss National Bank54,300$1.09M0.00%+3,000+5.8%Added
Engineers Gate Manager LP52,923$1.06M0.02%+34,201+182.7%Added
Dark Forest Capital Management LP51,855$1.04M0.05%+51,855New
UBS Group AG48,759$976.2K0.00%−763,841−94.0%Reduced
Campbell & CO Investment Adviser LLC45,849$917.9K0.07%−471−1.0%Reduced
BNP Paribas Arbitrage, SA45,230$905.5K0.00%−203,898−81.8%Reduced
Barclays PLC42,815$857.2K0.00%−6,198−12.6%Reduced
Tritonpoint Wealth, LLC41,637$833.6K0.08%−5,000−10.7%Reduced
Rhumbline Advisers39,186$784.5K0.00%−706−1.8%Reduced
Nebula Research & Development LLC37,617$753.1K0.07%+10,943+41.0%Added
ABG Innovation Capital Partners III GP Ltd36,747$735.7K91.94%00.0%Unchanged
Susquehanna International Group, LLP35,901$718.7K0.00%+18,467+105.9%Added
Healthcare of Ontario Pension Plan Trust Fund35,800$716.7K0.00%00.0%Unchanged
Los Angeles Capital Management LLC33,970$680.1K0.00%+33,970New
Perkins Capital Management Inc33,965$680.0K0.72%−200−0.6%Reduced
Alliancebernstein L.P.33,370$668.1K0.00%00.0%Unchanged
Invesco Ltd.32,251$645.7K0.00%+4,717+17.1%Added
Jane Street Group, LLC30,676$614.1K0.00%−28,707−48.3%Reduced
Verition Fund Management LLC30,671$614.0K0.00%+21,623+239.0%Added
Summit Global Investments30,640$613.0K0.04%+2,164+7.6%Added
JPMorgan Chase & Co30,577$612.2K0.00%−77,359−71.7%Reduced
HRT Financial LP28,285$566.0K0.00%+15,916+128.7%Added
Parallel Advisors, LLC27,593$550.8K0.01%−402−1.4%Reduced
Mackenzie Financial Corp27,460$549.7K0.00%+6,440+30.6%Added
Legal & General Group Plc25,916$518.8K0.00%−36−0.1%Reduced
California State Teachers Retirement System24,620$492.9K0.00%00.0%Unchanged
TownSquare Capital, LLC23,772$475.9K0.01%+1,584+7.1%Added
Price T Rowe Associates Inc23,705$475.0K0.00%+1,008+4.4%Added
Fan Yu22,503$450.5K0.46%00.0%Unchanged
Truist Financial Corp22,308$446.6K0.00%+1,005+4.7%Added
Jacobs Levy Equity Management, Inc21,299$426.4K0.00%−113,483−84.2%Reduced
Dynamic Technology Lab Private Ltd21,235$425.0K0.06%+3,605+20.4%Added
Cerity Partners LLC21,138$423.2K0.00%+21,138New
Hussman Strategic Advisors, Inc.21,000$420.4K0.10%−52,500−71.4%Reduced
EntryPoint Capital, LLC20,432$409.0K0.19%−8,712−29.9%Reduced
Advantage Alpha Capital Partners LP19,805$396.5K0.10%+19,805New
Balyasny Asset Management LLC19,730$395.0K0.00%+19,730New
XTX Topco Ltd19,628$393.0K0.02%+19,628New
HSBC Holdings PLC19,627$390.6K0.00%−46−0.2%Reduced