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Castle Biosciences Inc

CSTL
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001447362

In the last 90 days, Castle Biosciences Inc insiders filed 0 open-market purchases and 20 sales; 176 institutions reported holding it in 13F filings for Q2 2026, worth $653.8M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Castle Biosciences Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
159
−27 vs. Q3 2021
Shares held
21.5M
−44.4K (−0.2%) vs. Q3 2021
Total value
$918.6M
−$503.7M (−35.4%) vs. Q3 2021
New holders
21
64 more added
Sold out
48
49 more reduced

2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CSTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 159 institutions
Q1 2021: 175 institutionsQ2 2021: 182 institutionsQ3 2021: 188 institutionsQ4 2021: 159 institutionsQ1 2022: 160 institutionsQ2 2022: 146 institutionsQ3 2022: 157 institutionsQ4 2022: 153 institutionsQ1 2023: 148 institutionsQ2 2023: 130 institutionsQ3 2023: 135 institutionsQ4 2023: 153 institutionsQ1 2024: 151 institutionsQ2 2024: 159 institutionsQ3 2024: 185 institutionsQ4 2024: 197 institutionsQ1 2025: 180 institutionsQ2 2025: 152 institutionsQ3 2025: 173 institutionsQ4 2025: 195 institutionsQ1 2026: 186 institutionsQ2 2026: 176 institutions
Value heldQ4 2021: $918.6M
Q1 2021: $1.46BQ2 2021: $1.52BQ3 2021: $1.42BQ4 2021: $918.6MQ1 2022: $1.02BQ2 2022: $495.0MQ3 2022: $569.8MQ4 2022: $522.0MQ1 2023: $501.9MQ2 2023: $316.6MQ3 2023: $391.0MQ4 2023: $515.4MQ1 2024: $553.2MQ2 2024: $549.4MQ3 2024: $736.9MQ4 2024: $706.4MQ1 2025: $516.3MQ2 2025: $541.8MQ3 2025: $608.3MQ4 2025: $1.06BQ1 2026: $677.8MQ2 2026: $653.8M
Institutions holding CSTL and their total value by quarter
QuarterHoldersValue
Q2 2026176$653.8M
Q1 2026186$677.8M
Q4 2025195$1.06B
Q3 2025173$608.3M
Q2 2025152$541.8M
Q1 2025180$516.3M
Q4 2024197$706.4M
Q3 2024185$736.9M
Q2 2024159$549.4M
Q1 2024151$553.2M
Q4 2023153$515.4M
Q3 2023135$391.0M
Q2 2023130$316.6M
Q1 2023148$501.9M
Q4 2022153$522.0M
Q3 2022157$569.8M
Q2 2022146$495.0M
Q1 2022160$1.02B
Q4 2021159$918.6M
Q3 2021188$1.42B
Q2 2021182$1.52B
Q1 2021175$1.46B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Castle Biosciences Inc; share changes are against Q3 2021.

Institutions holding CSTL in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Wasatch Advisors Inc3,116,488$133.6M0.55%+622,786+25.0%Added
BlackRock Inc.1,801,387$77.2M0.00%+45,379+2.6%Added
ARK Investment Management LLCSuperinvestorARK Invest1,213,207$52.0M0.16%−844,660−41.0%Reduced
Vanguard Group Inc1,162,841$49.9M0.00%−3,347−0.3%Reduced
Invesco Ltd.1,049,660$45.0M0.01%+18,002+1.7%Added
Granahan Investment Management Inc737,374$31.6M0.65%+286,394+63.5%Added
Macquarie Group Ltd656,552$28.1M0.02%−12,509−1.9%Reduced
GW&K Investment Management, LLC610,292$26.2M0.22%+189,918+45.2%Added
RTW Investments, LP599,009$25.7M0.37%00.0%Unchanged
Sumitomo Mitsui Trust Holdings, Inc.533,677$22.9M0.01%+5,755+1.1%Added
Millennium Management LLC516,506$22.1M0.02%+113,147+28.1%Added
Nikko Asset Management Americas, Inc.533,677$21.9M0.12%+5,755+1.1%Added
Point72 Asset Management, L.P.482,852$20.7M0.09%+379,673+368.0%Added
State Street Corp456,039$19.6M0.00%+21,202+4.9%Added
Allspring Global Investments Holdings, LLC452,728$19.4M0.02%+452,728New
Kornitzer Capital Management Inc444,342$19.0M0.28%+100,525+29.2%Added
Geode Capital Management, LLC385,741$16.5M0.00%+20,373+5.6%Added
Pembroke Management, LTD383,372$16.4M1.20%−50,307−11.6%Reduced
Zevenbergen Capital Investments LLC369,031$15.8M0.33%−155,842−29.7%Reduced
Palisade Capital Management LLC352,441$15.1M0.31%+352,441New
Grandeur Peak Global Advisors, LLC338,457$14.5M0.66%+107,161+46.3%Added
Next Century Growth Investors LLC307,844$13.2M1.19%+32,402+11.8%Added
Northern Trust Corp218,662$9.37M0.00%−4,933−2.2%Reduced
ArrowMark Colorado Holdings LLC191,225$8.20M0.07%+139,992+273.2%Added
UBS Asset Management Americas Inc187,243$8.03M0.00%+8,588+4.8%Added
Principal Financial Group Inc182,667$7.83M0.00%+12,851+7.6%Added
Redwood Investments, LLC173,793$7.45M0.59%−1,868−1.1%Reduced
Charles Schwab Investment Management Inc161,915$6.94M0.00%+3,492+2.2%Added
Banque Pictet & Cie SA159,140$6.82M0.05%+133,137+512.0%Added
Lord, Abbett & Co. LLC158,810$6.81M0.02%−1,550−1.0%Reduced
Trustcore Financial Services, LLC142,866$6.13M0.69%00.0%Unchanged
Segall Bryant & Hamill, LLC138,957$5.96M0.06%+67,582+94.7%Added
Two Sigma Investments, LP135,367$5.80M0.01%+62,401+85.5%Added
Renaissance Technologies LLC134,281$5.76M0.01%+134,281New
New York State Common Retirement Fund128,176$5.50M0.01%+80,837+170.8%Added
Monarch Partners Asset Management LLC114,664$4.92M1.00%−47,804−29.4%Reduced
Dimensional Fund Advisors LP114,100$4.89M0.00%+59,783+110.1%Added
Two Sigma Advisers, LP111,500$4.78M0.01%+31,700+39.7%Added
Ameriprise Financial Inc109,321$4.69M0.00%+17,034+18.5%Added
King Luther Capital Management Corp109,030$4.67M0.02%+19,940+22.4%Added
Wells Fargo & Company107,722$4.62M0.00%−462,813−81.1%Reduced
Citadel Advisors LLC97,886$4.20M0.00%−132,553−57.5%Reduced
Essex Investment Management Co LLC91,935$3.94M0.45%−3,939−4.1%Reduced
DF Dent & Co Inc88,451$3.79M0.04%−12,109−12.0%Reduced
Bank of New York Mellon Corp87,228$3.74M0.00%−1,270−1.4%Reduced
Putnam Investments LLC77,152$3.31M0.00%+5,833+8.2%Added
Public Employees Retirement System of Ohio76,687$3.29M0.01%+20,433+36.3%Added
Goldman Sachs Group Inc71,408$3.06M0.00%−156,106−68.6%Reduced
Nuveen Asset Management, LLC70,991$2.76M0.00%−5,521−7.2%Reduced
Madison Asset Management, LLC60,911$2.61M0.03%+453+0.7%Added
Premier Fund Managers Ltd52,282$2.29M0.07%−29,772−36.3%Reduced
Polar Capital Holdings Plc44,985$1.93M0.01%+8,107+22.0%Added
Swiss National Bank44,300$1.90M0.00%00.0%Unchanged
Parametric Portfolio Associates LLC42,972$1.84M0.00%+9,862+29.8%Added
Morgan Stanley42,899$1.84M0.00%−26,923−38.6%Reduced
Schonfeld Strategic Advisors LLC41,114$1.76M0.02%−5,022−10.9%Reduced
Stanley-Laman Group, Ltd.39,974$1.71M0.20%+39,974New
Cubist Systematic Strategies, LLC39,541$1.70M0.02%+32,913+496.6%Added
Bank of America Corp38,801$1.66M0.00%+17,827+85.0%Added
Isthmus Partners, LLC37,809$1.62M0.27%+28,247+295.4%Added
Swedbank AB35,000$1.53M0.00%00.0%Unchanged
Squarepoint Ops LLC34,693$1.49M0.01%+34,693New
Envestnet Asset Management Inc33,439$1.43M0.00%+441+1.3%Added
Perkins Capital Management Inc33,170$1.42M0.96%+20+0.1%Added
Victory Capital Management Inc30,514$1.31M0.00%−289,145−90.5%Reduced
Jump Financial, LLC30,244$1.30M0.08%+24,544+430.6%Added
Parian Global Management LP29,498$1.26M1.15%+29,498New
California State Teachers Retirement System28,594$1.23M0.00%+688+2.5%Added
Brinker Capital Investments, LLC27,720$1.19M0.02%−22,441−44.7%Reduced
Oberweis Asset Management Inc26,260$1.13M0.21%00.0%Unchanged
Rice Hall James & Associates, LLC25,213$1.08M0.04%−3,531−12.3%Reduced
EMC Capital Management24,847$1.06M0.57%00.0%Unchanged
Alliancebernstein L.P.24,700$1.06M0.00%00.0%Unchanged
Bridgewater Associates, LP24,424$1.05M0.01%−46−0.2%Reduced
Capital Impact Advisors, LLC24,429$1.05M0.72%+7,726+46.3%Added
JPMorgan Chase & Co23,570$1.01M0.00%+1,477+6.7%Added
Knights of Columbus Asset Advisors LLC22,602$969.0K0.08%+400+1.8%Added
Parallel Advisors, LLC21,769$933.0K0.03%00.0%Unchanged
Covenant Partners, LLC21,279$912.0K0.34%00.0%Unchanged
Rhumbline Advisers20,898$896.0K0.00%−357−1.7%Reduced
Signaturefd, LLC19,415$832.0K0.03%+32+0.2%Added
United Capital Financial Advisers, LLC17,637$756.0K0.00%+197+1.1%Added
Advisors Capital Management, LLC17,013$729.0K0.02%+2,901+20.6%Added
State of Wisconsin Investment Board16,400$703.0K0.00%−4,900−23.0%Reduced
Citigroup Inc14,567$624.0K0.00%−1,061−6.8%Reduced
Chartwell Investment Partners, LLC13,901$596.0K0.02%−245−1.7%Reduced
Deutsche Bank AG13,810$592.0K0.00%−9,024−39.5%Reduced
Baird Financial Group, Inc.13,675$586.0K0.00%−366−2.6%Reduced
Voya Investment Management LLC13,502$579.0K0.00%+1,438+11.9%Added
Walleye Capital LLC13,443$576.0K0.02%+13,443New
Credit Suisse AG13,158$564.0K0.00%+365+2.9%Added
Qube Research & Technologies Ltd12,814$549.0K0.00%+6,299+96.7%Added
US Bancorp12,774$547.0K0.00%−816−6.0%Reduced
Susquehanna Fundamental Investments, LLC12,725$546.0K0.01%−5,255−29.2%Reduced
American International Group, Inc.11,323$485.0K0.00%−339−2.9%Reduced
Cambridge Investment Research Advisors, Inc.11,165$479.0K0.00%+110+1.0%Added
Manufacturers Life Insurance Company, The10,933$469.0K0.00%+208+1.9%Added
Susquehanna International Group, LLP10,707$459.0K0.00%+10,707New
UBS Group AG10,398$446.0K0.00%+9,142+727.9%Added
Claybrook Capital, LLC10,026$430.0K0.20%00.0%Unchanged