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Castle Biosciences Inc

CSTL
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001447362

In the last 90 days, Castle Biosciences Inc insiders filed 0 open-market purchases and 20 sales; 176 institutions reported holding it in 13F filings for Q2 2026, worth $653.8M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Castle Biosciences Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
159
−27 vs. Q3 2021
Shares held
21.5M
−44.4K (−0.2%) vs. Q3 2021
Total value
$918.6M
−$503.7M (−35.4%) vs. Q3 2021
New holders
21
64 more added
Sold out
48
49 more reduced

2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CSTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 159 institutions
Q1 2021: 175 institutionsQ2 2021: 182 institutionsQ3 2021: 188 institutionsQ4 2021: 159 institutionsQ1 2022: 160 institutionsQ2 2022: 146 institutionsQ3 2022: 157 institutionsQ4 2022: 153 institutionsQ1 2023: 148 institutionsQ2 2023: 130 institutionsQ3 2023: 135 institutionsQ4 2023: 153 institutionsQ1 2024: 151 institutionsQ2 2024: 159 institutionsQ3 2024: 185 institutionsQ4 2024: 197 institutionsQ1 2025: 180 institutionsQ2 2025: 152 institutionsQ3 2025: 173 institutionsQ4 2025: 195 institutionsQ1 2026: 186 institutionsQ2 2026: 176 institutions
Value heldQ4 2021: $918.6M
Q1 2021: $1.46BQ2 2021: $1.52BQ3 2021: $1.42BQ4 2021: $918.6MQ1 2022: $1.02BQ2 2022: $495.0MQ3 2022: $569.8MQ4 2022: $522.0MQ1 2023: $501.9MQ2 2023: $316.6MQ3 2023: $391.0MQ4 2023: $515.4MQ1 2024: $553.2MQ2 2024: $549.4MQ3 2024: $736.9MQ4 2024: $706.4MQ1 2025: $516.3MQ2 2025: $541.8MQ3 2025: $608.3MQ4 2025: $1.06BQ1 2026: $677.8MQ2 2026: $653.8M
Institutions holding CSTL and their total value by quarter
QuarterHoldersValue
Q2 2026176$653.8M
Q1 2026186$677.8M
Q4 2025195$1.06B
Q3 2025173$608.3M
Q2 2025152$541.8M
Q1 2025180$516.3M
Q4 2024197$706.4M
Q3 2024185$736.9M
Q2 2024159$549.4M
Q1 2024151$553.2M
Q4 2023153$515.4M
Q3 2023135$391.0M
Q2 2023130$316.6M
Q1 2023148$501.9M
Q4 2022153$522.0M
Q3 2022157$569.8M
Q2 2022146$495.0M
Q1 2022160$1.02B
Q4 2021159$918.6M
Q3 2021188$1.42B
Q2 2021182$1.52B
Q1 2021175$1.46B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Castle Biosciences Inc; share changes are against Q3 2021.

Institutions holding CSTL in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Price T Rowe Associates Inc9,944$426.0K0.00%+3,209+47.6%Added
Pictet & Cie (Europe) SA9,689$415.0K0.01%+1,065+12.3%Added
AlphaCentric Advisors LLC9,500$407.0K0.12%+9,500New
Valmark Advisers, Inc.9,284$398.0K0.01%+260+2.9%Added
Legal & General Group Plc8,984$385.0K0.00%+28+0.3%Added
Dynamic Technology Lab Private Ltd8,710$373.0K0.04%+8,710New
SG Americas Securities, LLC8,227$353.0K0.00%−3,419−29.4%Reduced
ProShare Advisors LLC8,218$352.0K0.00%+111+1.4%Added
Handelsbanken Fonder AB8,000$343.0K0.00%−200−2.4%Reduced
Mesirow Financial Investment Management, Inc.7,960$341.0K0.98%00.0%Unchanged
First Trust Advisors LP7,936$340.0K0.00%−7,613−49.0%Reduced
MetLife Investment Management7,804$334.6K0.00%00.0%Unchanged
First Republic Investment Management, Inc.7,629$327.0K0.00%+7,629New
Advisor Group Holdings, Inc.7,245$310.0K0.00%+678+10.3%Added
NinePointTwo Capital6,965$298.0K0.10%+6,965New
DekaBank Deutsche Girozentrale7,200$296.0K0.00%+200+2.9%Added
Aristides Capital LLC6,910$296.0K0.17%+6,910New
Truist Financial Corp6,131$262.0K0.00%−237−3.7%Reduced
Metropolitan Life Insurance Co5,975$256.1K0.00%00.0%Unchanged
Prudential Financial Inc4,271$256.0K0.00%−585−12.0%Reduced
Prelude Capital Management, LLC5,855$251.0K0.01%+707+13.7%Added
Cullen/Frost Bankers, Inc.5,430$233.0K0.00%+1,605+42.0%Added
Arizona State Retirement System5,419$232.0K0.00%−41−0.8%Reduced
Commerce Bank5,260$226.0K0.00%+5,260New
Zurcher Kantonalbank (Zurich Cantonalbank)5,076$218.0K0.00%−75−1.5%Reduced
Royal Bank of Canada5,004$214.0K0.00%+1,977+65.3%Added
First Bank & Trust3,377$145.0K0.06%+2,344+226.9%Added
Quantbot Technologies LP3,081$132.0K0.01%−6,517−67.9%Reduced
STRS Ohio2,800$120.0K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.2,455$105.0K0.00%+960+64.2%Added
Amundi2,350$87.0K0.00%+1,689+255.5%Added
Ameritas Investment Partners, Inc.1,671$72.0K0.00%00.0%Unchanged
Great West Life Assurance Co971$41.0K0.00%00.0%Unchanged
Ensign Peak Advisors, Inc890$38.0K0.00%+890New
NEXT Financial Group, Inc557$24.0K0.00%−2,595−82.3%Reduced
State of Wyoming566$24.0K0.01%−18−3.1%Reduced
Harbor Investment Advisory, LLC542$23.0K0.00%00.0%Unchanged
Creative Financial Designs Inc500$21.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)443$19.0K0.00%−2,236−83.5%Reduced
First Horizon Advisors, Inc.460$19.0K0.00%−101−18.0%Reduced
Captrust Financial Advisors432$19.0K0.00%−67−13.4%Reduced
Baillie Gifford & Co225$10.0K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC200$9.00K0.00%−200−50.0%Reduced
Rockefeller Capital Management L.P.200$8.00K0.00%00.0%Unchanged
Simplex Trading, LLC177$7.00K0.00%−1,443−89.1%Reduced
TCI Wealth Advisors, Inc.145$6.00K0.00%+67+85.9%Added
Healthcare of Ontario Pension Plan Trust Fund108$5.00K0.00%00.0%Unchanged
Confluence Wealth Services, Inc.127$5.00K0.00%+127New
Dark Forest Capital Management LP87$4.00K0.00%−9,640−99.1%Reduced
Assetmark, Inc100$4.00K0.00%−225−69.2%Reduced
Daiwa Securities Group Inc.86$4.00K0.00%00.0%Unchanged
Global Retirement Partners, LLC50$2.00K0.00%00.0%Unchanged
Huntington National Bank42$2.00K0.00%+42New
Howe & Rusling Inc33$1.00K0.00%00.0%Unchanged
FourThought Financial, LLC28$1.00K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.12$1.00K0.00%+12New
Missouri Trust & Investment Co19$1.00K0.00%+19New
CWM, LLC2$00.00%+2New
Covestor Ltd7$00.00%+7New
Driehaus Capital Management LLC0$00.00%−358,200−100.0%Sold out
Intrinsic Edge Capital Management LLC0$00.00%−147,895−100.0%Sold out
Castleark Management LLC0$00.00%−147,867−100.0%Sold out
CastleArk Alternatives, LLC0$00.00%−147,867−100.0%Sold out
Calamos Advisors LLC0$00.00%−131,984−100.0%Sold out
M&G Investment Management Ltd0$00.00%−95,351−100.0%Sold out
Polar Asset Management Partners Inc.0$00.00%−95,504−100.0%Sold out
Russell Investments Group, Ltd.0$00.00%−88,774−100.0%Sold out
Fred Alger Management, LLC0$00.00%−80,293−100.0%Sold out
Altium Capital Management LP0$00.00%−72,500−100.0%Sold out
Bank of Montreal0$00.00%−44,818−100.0%Sold out
Lisanti Capital Growth, LLC0$00.00%−35,855−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−18,169−100.0%Sold out
Jane Street Group, LLC0$00.00%−16,423−100.0%Sold out
Martingale Asset Management L P0$00.00%−13,555−100.0%Sold out
Advisory Research Inc0$00.00%−12,368−100.0%Sold out
SEI Investments Co0$00.00%−9,374−100.0%Sold out
Old Mission Capital LLC0$00.00%−7,500−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−7,104−100.0%Sold out
Ergoteles LLC0$00.00%−5,400−100.0%Sold out
PDT Partners, LLC0$00.00%−5,351−100.0%Sold out
Level Four Advisory Services, LLC0$00.00%−5,265−100.0%Sold out
Commonwealth Equity Services, LLC0$00.00%−5,071−100.0%Sold out
HRT Financial LP0$00.00%−4,725−100.0%Sold out
Winton Group Ltd0$00.00%−4,607−100.0%Sold out
Oppenheimer Asset Management Inc.0$00.00%−4,374−100.0%Sold out
State Board of Administration of Florida Retirement System0$00.00%−4,016−100.0%Sold out
MML Investors Services, LLC0$00.00%−3,712−100.0%Sold out
Amalgamated Bank0$00.00%−3,709−100.0%Sold out
Versor Investments LP0$00.00%−3,700−100.0%Sold out
TownSquare Capital, LLC0$00.00%−3,702−100.0%Sold out
Park Avenue Securities LLC0$00.00%−3,670−100.0%Sold out
Cherry Creek Investment Advisors, Inc.0$00.00%−3,585−100.0%Sold out
Los Angeles Capital Management LLC0$00.00%−3,282−100.0%Sold out
M&T Bank Corp0$00.00%−3,186−100.0%Sold out
Teacher Retirement System of Texas0$00.00%−3,193−100.0%Sold out
First Quadrant L P0$00.00%−2,501−100.0%Sold out
Harbour Investments, Inc.0$00.00%−950−100.0%Sold out
O'Shaughnessy Asset Management, LLC0$00.00%−606−100.0%Sold out
Penserra Capital Management LLC0$00.00%−575−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−116−100.0%Sold out