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Castle Biosciences Inc

CSTL
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001447362

In the last 90 days, Castle Biosciences Inc insiders filed 0 open-market purchases and 20 sales; 176 institutions reported holding it in 13F filings for Q2 2026, worth $653.8M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Castle Biosciences Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
152
−26 vs. Q1 2025
Shares held
26.5M
+744.7K (+2.9%) vs. Q1 2025
Total value
$541.8M
+$27.1M (+5.3%) vs. Q1 2025
New holders
16
69 more added
Sold out
42
45 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CSTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 152 institutions
Q1 2021: 175 institutionsQ2 2021: 182 institutionsQ3 2021: 188 institutionsQ4 2021: 159 institutionsQ1 2022: 160 institutionsQ2 2022: 146 institutionsQ3 2022: 157 institutionsQ4 2022: 153 institutionsQ1 2023: 148 institutionsQ2 2023: 130 institutionsQ3 2023: 135 institutionsQ4 2023: 153 institutionsQ1 2024: 151 institutionsQ2 2024: 159 institutionsQ3 2024: 185 institutionsQ4 2024: 197 institutionsQ1 2025: 180 institutionsQ2 2025: 152 institutionsQ3 2025: 173 institutionsQ4 2025: 195 institutionsQ1 2026: 186 institutionsQ2 2026: 176 institutions
Value heldQ2 2025: $541.8M
Q1 2021: $1.46BQ2 2021: $1.52BQ3 2021: $1.42BQ4 2021: $918.6MQ1 2022: $1.02BQ2 2022: $495.0MQ3 2022: $569.8MQ4 2022: $522.0MQ1 2023: $501.9MQ2 2023: $316.6MQ3 2023: $391.0MQ4 2023: $515.4MQ1 2024: $553.2MQ2 2024: $549.4MQ3 2024: $736.9MQ4 2024: $706.4MQ1 2025: $516.3MQ2 2025: $541.8MQ3 2025: $608.3MQ4 2025: $1.06BQ1 2026: $677.8MQ2 2026: $653.8M
Institutions holding CSTL and their total value by quarter
QuarterHoldersValue
Q2 2026176$653.8M
Q1 2026186$677.8M
Q4 2025195$1.06B
Q3 2025173$608.3M
Q2 2025152$541.8M
Q1 2025180$516.3M
Q4 2024197$706.4M
Q3 2024185$736.9M
Q2 2024159$549.4M
Q1 2024151$553.2M
Q4 2023153$515.4M
Q3 2023135$391.0M
Q2 2023130$316.6M
Q1 2023148$501.9M
Q4 2022153$522.0M
Q3 2022157$569.8M
Q2 2022146$495.0M
Q1 2022160$1.02B
Q4 2021159$918.6M
Q3 2021188$1.42B
Q2 2021182$1.52B
Q1 2021175$1.46B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Castle Biosciences Inc; share changes are against Q1 2025.

Institutions holding CSTL in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.3,154,679$64.4M0.00%+171,139+5.7%Added
Vanguard Group Inc2,170,028$44.3M0.00%+122,463+6.0%Added
Principal Financial Group Inc1,798,974$36.7M0.02%+331,101+22.6%Added
Portolan Capital Management, LLC1,489,572$30.4M1.91%+224,349+17.7%Added
Dimensional Fund Advisors LP1,378,005$28.1M0.01%+177,783+14.8%Added
Nuveen, LLC1,073,107$21.9M0.01%+401,296+59.7%Added
Wasatch Advisors Inc1,049,773$21.4M0.11%+51,318+5.1%Added
Citadel Advisors LLC888,515$18.1M0.02%+630,133+243.9%Added
Braidwell LP822,735$16.8M0.57%+457,488+125.3%Added
Allianz Asset Management GmbH713,742$14.6M0.02%+74,265+11.6%Added
State Street Corp707,687$14.5M0.00%−7,341−1.0%Reduced
Geode Capital Management, LLC689,926$14.1M0.00%+40,073+6.2%Added
Renaissance Technologies LLC670,500$13.7M0.02%−30,700−4.4%Reduced
Schroder Investment Management Group648,572$13.2M0.01%+51,483+8.6%Added
Palisade Capital Management LLC575,116$11.7M0.33%+85,148+17.4%Added
Acadian Asset Management LLC544,250$11.1M0.02%−131,816−19.5%Reduced
Millennium Management LLC428,397$8.75M0.01%+173,648+68.2%Added
Wellington Management Group LLP407,211$8.32M0.00%−421,317−50.9%Reduced
Bank of America Corp382,745$7.82M0.00%+7,365+2.0%Added
Ameriprise Financial Inc372,467$7.61M0.00%+46,770+14.4%Added
UBS Group AG363,848$7.43M0.00%+315,089+646.2%Added
Parkman Healthcare Partners LLC352,262$7.19M0.83%+1,711+0.5%Added
Trexquant Investment LP318,072$6.50M0.07%+69,081+27.7%Added
Silvercrest Asset Management Group LLC279,959$5.72M0.04%+81,157+40.8%Added
Northern Trust Corp279,825$5.71M0.00%+6,356+2.3%Added
Kornitzer Capital Management Inc278,314$5.68M0.11%00.0%Unchanged
Goldman Sachs Group Inc273,443$5.58M0.00%+98,118+56.0%Added
Advisors Capital Management, LLC245,867$5.02M0.07%+44,180+21.9%Added
Charles Schwab Investment Management Inc235,015$4.80M0.00%−7,243−3.0%Reduced
New York State Common Retirement Fund215,830$4.41M0.01%+52,671+32.3%Added
Qube Research & Technologies Ltd192,553$3.93M0.01%−86,811−31.1%Reduced
Algert Global LLC185,181$3.78M0.08%+40,870+28.3%Added
Morgan Stanley167,588$3.42M0.00%−44,205−20.9%Reduced
Allspring Global Investments Holdings, LLC161,175$3.29M0.01%−56,619−26.0%Reduced
D. E. Shaw & Co., Inc.148,190$3.03M0.00%−40,987−21.7%Reduced
Connor, Clark & Lunn Investment Management Ltd.126,431$2.58M0.01%−50,458−28.5%Reduced
Squarepoint Ops LLC125,719$2.57M0.01%+28,359+29.1%Added
Birchview Capital, LP110,600$2.26M2.24%+22,196+25.1%Added
Barclays PLC109,743$2.24M0.00%+66,928+156.3%Added
UBS Asset Management Americas Inc102,742$2.10M0.00%+34,711+51.0%Added
BNP Paribas Arbitrage, SA99,293$2.03M0.00%+54,063+119.5%Added
Franklin Resources Inc99,247$2.03M0.00%+161+0.2%Added
Bank of New York Mellon Corp89,883$1.84M0.00%+5,842+7.0%Added
Y-Intercept (Hong Kong) Ltd78,938$1.61M0.04%+78,938New
Brinker Capital Investments, LLC76,532$1.56M0.01%−1,877−2.4%Reduced
Tudor Investment Corp Et Al76,454$1.56M0.01%−94,928−55.4%Reduced
Envestnet Asset Management Inc70,478$1.44M0.00%+707+1.0%Added
Schonfeld Strategic Advisors LLC67,926$1.39M0.01%+8,255+13.8%Added
Engineers Gate Manager LP67,252$1.37M0.02%+14,329+27.1%Added
American Century Companies Inc65,272$1.33M0.00%−8,795−11.9%Reduced
Deutsche Bank AG61,743$1.26M0.00%−3,794−5.8%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH54,610$1.12M0.00%+42,857+364.6%Added
Swiss National Bank54,300$1.11M0.00%00.0%Unchanged
AQR Capital Management LLC49,230$1.01M0.00%−87,792−64.1%Reduced
XTX Topco Ltd46,301$945.5K0.04%+26,673+135.9%Added
Rhumbline Advisers45,397$927.0K0.00%+6,211+15.9%Added
Nebula Research & Development LLC44,472$908.1K0.08%+6,855+18.2%Added
Susquehanna International Group, LLP42,853$875.1K0.00%+6,952+19.4%Added
Graham Capital Management, L.P.41,783$853.2K0.03%−26,602−38.9%Reduced
Brevan Howard Capital Management LP41,301$843.4K0.01%+29,096+238.4%Added
Tritonpoint Wealth, LLC40,777$832.7K0.08%−860−2.1%Reduced
Bridgeway Capital Management, LLC40,750$832.1K0.02%+40,750New
Empowered Funds, LLC40,750$832.1K0.01%+40,750New
Invesco Ltd.40,429$825.6K0.00%+8,178+25.4%Added
Healthcare of Ontario Pension Plan Trust Fund35,800$731.0K0.00%00.0%Unchanged
Legal & General Group Plc34,908$712.8K0.00%+8,992+34.7%Added
HSBC Holdings PLC34,018$690.7K0.00%+14,391+73.3%Added
Alliancebernstein L.P.33,370$681.4K0.00%00.0%Unchanged
Verition Fund Management LLC31,539$644.0K0.00%+868+2.8%Added
SEI Investments Co31,130$635.7K0.00%−41,929−57.4%Reduced
Two Sigma Investments, LP28,241$576.7K0.00%−111,544−79.8%Reduced
Perkins Capital Management Inc27,995$571.7K0.57%−5,970−17.6%Reduced
Parallel Advisors, LLC27,893$569.6K0.01%+300+1.1%Added
JPMorgan Chase & Co26,663$544.5K0.00%−3,914−12.8%Reduced
Price T Rowe Associates Inc26,407$540.0K0.00%+2,702+11.4%Added
California State Teachers Retirement System24,620$502.7K0.00%00.0%Unchanged
Mackenzie Financial Corp24,204$494.2K0.00%−3,256−11.9%Reduced
Truist Financial Corp24,023$490.6K0.00%+1,715+7.7%Added
FMR LLC24,000$490.1K0.00%+22,844+1,976.1%Added
Jump Financial, LLC21,858$446.3K0.01%+21,858New
Harbor Capital Advisors, Inc.20,399$417.0K0.02%+3,804+22.9%Added
Wells Fargo & Company20,300$414.5K0.00%+3,953+24.2%Added
First Bank & Trust19,951$407.4K0.07%+4,815+31.8%Added
Aquatic Capital Management LLC19,280$393.7K0.01%+19,280New
CWM Advisors, LLC19,117$390.4K0.04%+1,964+11.4%Added
HRT Financial LP18,826$384.0K0.00%−9,459−33.4%Reduced
Oak Harvest Investment Services16,883$344.8K0.04%00.0%Unchanged
Advantage Alpha Capital Partners LP16,021$327.1K0.09%−3,784−19.1%Reduced
MetLife Investment Management15,881$324.3K0.00%+152+1.0%Added
Summit Global Investments15,649$320.0K0.02%−14,991−48.9%Reduced
Mirae Asset Global ETFs Holdings Ltd.15,561$317.8K0.00%+120+0.8%Added
Citigroup Inc14,072$287.4K0.00%−48,629−77.6%Reduced
Simon Quick Advisors, LLC13,562$276.9K0.01%−33−0.2%Reduced
Intech Investment Management LLC12,289$250.9K0.00%−3,789−23.6%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)12,089$246.9K0.00%+8+0.1%Added
Two Sigma Advisers, LP12,000$245.0K0.00%−57,200−82.7%Reduced
STRS Ohio11,700$238.9K0.00%−6,600−36.1%Reduced
Diversify Wealth Management, LLC12,322$238.3K0.01%−780−6.0%Reduced
Stephens Inc11,386$232.5K0.00%−2,253−16.5%Reduced
Creative Planning11,111$226.9K0.00%+11+0.1%Added