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Castle Biosciences Inc

CSTL
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001447362

In the last 90 days, Castle Biosciences Inc insiders filed 0 open-market purchases and 20 sales; 176 institutions reported holding it in 13F filings for Q2 2026, worth $653.8M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Castle Biosciences Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
173
+22 vs. Q2 2025
Shares held
26.6M
+114.3K (+0.4%) vs. Q2 2025
Total value
$608.3M
+$66.6M (+12.3%) vs. Q2 2025
New holders
37
62 more added
Sold out
15
53 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CSTL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 173 institutions
Q1 2021: 175 institutionsQ2 2021: 182 institutionsQ3 2021: 188 institutionsQ4 2021: 159 institutionsQ1 2022: 160 institutionsQ2 2022: 146 institutionsQ3 2022: 157 institutionsQ4 2022: 153 institutionsQ1 2023: 148 institutionsQ2 2023: 130 institutionsQ3 2023: 135 institutionsQ4 2023: 153 institutionsQ1 2024: 151 institutionsQ2 2024: 159 institutionsQ3 2024: 185 institutionsQ4 2024: 197 institutionsQ1 2025: 180 institutionsQ2 2025: 152 institutionsQ3 2025: 173 institutionsQ4 2025: 195 institutionsQ1 2026: 186 institutionsQ2 2026: 176 institutions
Value heldQ3 2025: $608.3M
Q1 2021: $1.46BQ2 2021: $1.52BQ3 2021: $1.42BQ4 2021: $918.6MQ1 2022: $1.02BQ2 2022: $495.0MQ3 2022: $569.8MQ4 2022: $522.0MQ1 2023: $501.9MQ2 2023: $316.6MQ3 2023: $391.0MQ4 2023: $515.4MQ1 2024: $553.2MQ2 2024: $549.4MQ3 2024: $736.9MQ4 2024: $706.4MQ1 2025: $516.3MQ2 2025: $541.8MQ3 2025: $608.3MQ4 2025: $1.06BQ1 2026: $677.8MQ2 2026: $653.8M
Institutions holding CSTL and their total value by quarter
QuarterHoldersValue
Q2 2026176$653.8M
Q1 2026186$677.8M
Q4 2025195$1.06B
Q3 2025173$608.3M
Q2 2025152$541.8M
Q1 2025180$516.3M
Q4 2024197$706.4M
Q3 2024185$736.9M
Q2 2024159$549.4M
Q1 2024151$553.2M
Q4 2023153$515.4M
Q3 2023135$391.0M
Q2 2023130$316.6M
Q1 2023148$501.9M
Q4 2022153$522.0M
Q3 2022157$569.8M
Q2 2022146$495.0M
Q1 2022160$1.02B
Q4 2021159$918.6M
Q3 2021188$1.42B
Q2 2021182$1.52B
Q1 2021175$1.46B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Castle Biosciences Inc; share changes are against Q2 2025.

Institutions holding CSTL in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Intech Investment Management LLC12,392$282.2K0.00%+103+0.8%Added
Summit Global Investments12,352$281.0K0.02%−3,297−21.1%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)12,207$278.0K0.00%+118+1.0%Added
Bailard, Inc.11,400$259.6K0.01%+11,400New
Stephens Inc11,122$253.2K0.00%−264−2.3%Reduced
Great West Life Assurance Co10,713$239.0K0.00%00.0%Unchanged
Magnetar Financial LLC10,327$235.1K0.00%+10,327New
Glenmede Investment Management, LP10,199$232.2K0.00%+10,199New
Lido Advisors, LLC10,036$228.5K0.00%+50.0%Added
Two Sigma Advisers, LP9,900$225.4K0.00%−2,100−17.5%Reduced
Atom Investors LP9,827$223.8K0.02%+9,827New
STRS Ohio9,800$223.1K0.00%−1,900−16.2%Reduced
Manufacturers Life Insurance Company, The9,539$217.2K0.00%−777−7.5%Reduced
Green Alpha Advisors, LLC9,538$217.2K0.21%+9,538New
LPL Financial LLC9,397$214.0K0.00%+9,397New
Janus Henderson Group PLC9,137$208.2K0.00%+9,137New
KLP Kapitalforvaltning AS8,900$202.7K0.00%+4,100+85.4%Added
Police & Firemen's Retirement System of New Jersey7,829$178.3K0.00%+1,992+34.1%Added
Assetmark, Inc5,705$129.9K0.00%+1,158+25.5%Added
China Universal Asset Management Co., Ltd.5,085$115.8K0.01%−714−12.3%Reduced
Citigroup Inc4,250$96.8K0.00%−9,822−69.8%Reduced
Tower Research Capital LLC (TRC)3,666$83.5K0.00%+875+31.4%Added
Harbour Investments, Inc.3,137$71.4K0.00%+150+5.0%Added
Russell Investments Group, Ltd.2,508$57.1K0.00%+976+63.7%Added
Canada Pension Plan Investment Board2,400$54.6K0.00%+2,400New
Point72 (DIFC) Ltd2,386$54.3K0.00%+2,386New
Ameritas Investment Partners, Inc.2,373$54.0K0.00%−527−18.2%Reduced
Aquatic Capital Management LLC2,335$53.2K0.00%−16,945−87.9%Reduced
Covestor Ltd2,069$47.0K0.03%−311−13.1%Reduced
Sterling Capital Management LLC1,960$44.6K0.00%+1,193+155.5%Added
CWM, LLC1,911$44.0K0.00%+853+80.6%Added
State of Alaska, Department of Revenue1,553$35.0K0.00%+1,553New
Simplex Trading, LLC1,512$34.0K0.00%+1,512New
Farther Finance Advisors, LLC1,392$31.7K0.00%+1,391+139,100.0%Added
Mirae Asset Global Investments Co., Ltd.1,121$25.5K0.00%+6+0.5%Added
Global Retirement Partners, LLC1,100$25.0K0.00%−63−5.4%Reduced
Royal Bank of Canada897$20.0K0.00%−9,676−91.5%Reduced
Amalgamated Bank893$20.0K0.00%00.0%Unchanged
Group One Trading, L.P.803$18.3K0.00%+803New
Caitong International Asset Management Co., Ltd728$16.6K0.01%+622+586.8%Added
Hughes Financial Services, LLC435$15.1K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.624$14.2K0.00%−92−12.8%Reduced
SRS Capital Advisors, Inc.574$13.1K0.00%+574New
First Horizon Corp447$10.2K0.00%+447New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.461$10.0K0.00%+33+7.7%Added
Advisor Group Holdings, Inc.408$9.26K0.00%+209+105.0%Added
Rossby Financial, LCC382$8.79K0.00%+240+169.0%Added
Nisa Investment Advisors, LLC364$8.29K0.00%+44+13.8%Added
Quadrant Capital Group LLC336$7.65K0.00%+336New
Versant Capital Management, Inc181$4.12K0.00%+55+43.7%Added
Huntington National Bank139$3.17K0.00%−58−29.4%Reduced
Essential Partners LLC123$2.80K0.00%+123New
The PNC Financial Services Group, Inc.115$2.62K0.00%+5+4.5%Added
Point72 Europe (London) LLP112$2.56K0.00%+112New
BFSG, LLC90$2.05K0.00%00.0%Unchanged
Daiwa Securities Group Inc.86$2.00K0.00%00.0%Unchanged
Principal Securities, Inc.76$1.73K0.00%00.0%Unchanged
Rothschild Investment LLC55$1.25K0.00%−30−35.3%Reduced
SBI Securities Co., Ltd.53$1.21K0.00%+3+6.0%Added
GAMMA Investing LLC52$1.18K0.00%−80−60.6%Reduced
IFP Advisors, Inc52$1.18K0.00%+16+44.4%Added
Spire Wealth Management50$1.14K0.00%00.0%Unchanged
Signaturefd, LLC45$1.02K0.00%00.0%Unchanged
Optiver Holding B.V.40$9110.00%+40New
US Bancorp26$5920.00%+26New
Jones Financial Companies LLLP25$5680.00%00.0%Unchanged
EverSource Wealth Advisors, LLC20$4550.00%−27−57.4%Reduced
Missouri Trust & Investment Co19$4330.00%00.0%Unchanged
Allworth Financial LP19$4330.00%+14+280.0%Added
Clearstead Advisors, LLC12$2740.00%+12New
Advisory Services Network, LLC7$1590.00%+7New
Larson Financial Group LLC1$230.00%+1New
True Wealth Design, LLC1$230.00%+1New
Wellington Management Group LLP0$00.00%−407,211−100.0%Sold out
Squarepoint Ops LLC0$00.00%−125,719−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−78,938−100.0%Sold out
XTX Topco Ltd0$00.00%−46,301−100.0%Sold out
Nebula Research & Development LLC0$00.00%−44,472−100.0%Sold out
Jump Financial, LLC0$00.00%−21,858−100.0%Sold out
Advantage Alpha Capital Partners LP0$00.00%−16,021−100.0%Sold out
Mount Yale Investment Advisors, LLC0$00.00%−8,362−100.0%Sold out
Raymond James Financial Inc0$00.00%−662−100.0%Sold out
Lazard Asset Management LLC0$00.00%−72−100.0%Sold out
Bryn Mawr Trust Co0$00.00%−46−100.0%Sold out
Parkside Financial Bank & Trust0$00.00%−25−100.0%Sold out
Skopos Labs, Inc.0$00.00%−11−100.0%Sold out
Stephens Consulting, LLC0$00.00%−2−100.0%Sold out
Twin Peaks Wealth Advisors, LLC0$00.00%−1−100.0%Sold out
First Horizon Advisors, Inc.––––Not filed