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Castle Biosciences Inc

CSTL
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001447362

In the last 90 days, Castle Biosciences Inc insiders filed 0 open-market purchases and 21 sales; 176 institutions reported holding it in 13F filings for Q2 2026, worth $653.8M in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Castle Biosciences Inc changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of CSTL: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders1734195+26
Shares26.6M63.0K27.3M+724.4K (+2.7%)
Value$608.3M$1.43M$1.06B+$455.1M (+75.0%)

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (43)

Institutions that held Castle Biosciences Inc at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to CSTL in Q4 2025
InstitutionSharesValue% of portfolio
RTW Investments, LP2,115,237$82.3M0.82%
Eventide Asset Management, LLC305,000$11.9M0.19%
Wellington Management Group LLP218,560$8.50M0.00%
EAM Investors, LLC74,138$2.88M0.32%
Squarepoint Ops LLC55,118$2.14M0.00%
Caxton Associates LLP22,464$873.9K0.02%
XTX Topco Ltd22,125$860.7K0.02%
Y-Intercept (Hong Kong) Ltd13,246$515.3K0.01%
Counterpoint Mutual Funds LLC12,952$503.8K0.04%
Man Group plc11,585$450.7K0.00%
Jackson Creek Investment Advisors LLC11,235$437.0K0.13%
TritonPoint Partners, LLC10,777$419.2K0.22%
Quantinno Capital Management LP9,332$363.0K0.00%
Cetera Investment Advisers8,935$347.6K0.00%
Glenmede Trust Co NA8,190$318.6K0.00%
Arizona State Retirement System8,071$314.0K0.00%
Intrust Bank NA7,378$287.0K0.02%
State Board of Administration of Florida Retirement System7,154$278.3K0.00%
Verdad Advisers, LP7,085$275.6K0.32%
Arrowstreet Capital, Limited Partnership7,029$273.4K0.00%
Commonwealth Equity Services, LLC6,591$256.4K0.00%
ProShare Advisors LLC6,478$252.0K0.00%
Blueshift Asset Management, LLC6,458$251.2K0.07%
Capstone Capital Management Ltd6,446$250.7K0.24%
Cornerstone Investment Partners, LLC6,078$236.4K0.01%
Portside Wealth Group, LLC5,942$231.1K0.03%
Pictet Asset Management Holding SA5,899$229.5K0.00%
Jump Financial, LLC5,500$213.9K0.00%
Voya Investment Management LLC5,246$204.1K0.00%
Raymond James Financial Inc5,238$203.8K0.00%
Globeflex Capital L P3,759$146.2K0.02%
State of Wyoming3,014$117.2K0.01%
Persistent Asset Partners Ltd2,463$95.8K0.05%
Kemnay Advisory Services Inc.889$34.6K0.01%
Federated Hermes, Inc.660$25.7K0.00%
Aster Capital Management (DIFC) Ltd151$5.87K0.00%
Rockefeller Capital Management L.P.87$3.38K0.00%
Quantbot Technologies LP47$1.83K0.00%
Northwestern Mutual Wealth Management Co28$1.09K0.00%
Parkside Financial Bank & Trust25$9730.00%
Torren Management, LLC21$8170.00%
Signature Equity Partners, LLC16$6220.00%
Sunbelt Securities, Inc.1$390.00%

Sold out (17)

Institutions that held Castle Biosciences Inc at the end of Q3 2025 and filed for Q4 2025 without it.

Not filed for Q4 2025 yet (4)

Institutions that held Castle Biosciences Inc at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding CSTL in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Cubist Systematic Strategies, LLC50,304$1.15M
Glenmede Investment Management, LP10,199$232.2K
Point72 (DIFC) Ltd2,386$54.3K
Point72 Europe (London) LLP112$2.56K