Caribou Biosciences, Inc.
CRBU- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001619856
No open-market purchases or sales by Caribou Biosciences, Inc. insiders were filed in the last 90 days; 137 institutions reported holding it in 13F filings for Q2 2026, worth $84.8M in total; Maverick Capital is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Caribou Biosciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 124
- +11 vs. Q3 2025
- Shares held
- 37.1M
- +110.9K (+0.3%) vs. Q3 2025
- Total value
- $58.8M
- −$27.8M (−32.1%) vs. Q3 2025
- New holders
- 25
- 28 more added
- Sold out
- 14
- 36 more reduced
4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CRBU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 137 | $84.8M |
| Q1 2026 | 137 | $71.3M |
| Q4 2025 | 124 | $58.8M |
| Q3 2025 | 117 | $87.0M |
| Q2 2025 | 129 | $51.2M |
| Q1 2025 | 131 | $45.8M |
| Q4 2024 | 133 | $93.1M |
| Q3 2024 | 129 | $103.1M |
| Q2 2024 | 140 | $87.6M |
| Q1 2024 | 151 | $343.0M |
| Q4 2023 | 144 | $395.8M |
| Q3 2023 | 126 | $338.5M |
| Q2 2023 | 121 | $185.5M |
| Q1 2023 | 126 | $238.3M |
| Q4 2022 | 133 | $273.8M |
| Q3 2022 | 113 | $456.8M |
| Q2 2022 | 120 | $203.0M |
| Q1 2022 | 104 | $313.2M |
| Q4 2021 | 93 | $464.7M |
| Q3 2021 | 88 | $704.7M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Caribou Biosciences, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Pfizer Inc | 4,690,431 | $7.46M | 3.15% | 00.0% | Unchanged |
| Vanguard Group Inc | 4,304,198 | $6.84M | 0.00% | +77,272+1.8% | Added |
| Kynam Capital Management, LP | 2,503,302 | $3.98M | 0.26% | −564,472−18.4% | Reduced |
| BlackRock, Inc. | 2,141,023 | $3.40M | 0.00% | +681,703+46.7% | Added |
| Renaissance Technologies LLC | 1,639,857 | $2.61M | 0.00% | +859,436+110.1% | Added |
| Standard Life Aberdeen plc | 1,388,905 | $2.21M | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 1,115,700 | $1.77M | 0.00% | −111,700−9.1% | Reduced |
| Susquehanna International Group, LLP | 1,031,375 | $1.64M | 0.00% | +585,768+131.5% | Added |
| Two Sigma Investments, LP | 1,020,079 | $1.62M | 0.00% | +236,489+30.2% | Added |
| Dimensional Fund Advisors LP | 1,006,010 | $1.60M | 0.00% | −204,300−16.9% | Reduced |
| Bank of America Corp | 993,186 | $1.58M | 0.00% | −81,256−7.6% | Reduced |
| Geode Capital Management, LLC | 976,813 | $1.55M | 0.00% | −8,313−0.8% | Reduced |
| PFM Health Sciences, LP | 957,787 | $1.52M | 0.15% | −401,044−29.5% | Reduced |
| Marshall Wace, LLP | 881,105 | $1.40M | 0.00% | +755,261+600.2% | Added |
| Jacobs Levy Equity Management, Inc | 824,299 | $1.31M | 0.01% | +475,216+136.1% | Added |
| Millennium Management LLC | 767,002 | $1.22M | 0.00% | −2,449,533−76.2% | Reduced |
| FMR LLC | 725,968 | $1.15M | 0.00% | −3,034−0.4% | Reduced |
| Maverick Capital LtdSuperinvestorMaverick Capital | 652,542 | $1.04M | 0.01% | 00.0% | Unchanged |
| UBS Group AG | 637,745 | $1.01M | 0.00% | +318,453+99.7% | Added |
| Cambridge Investment Research Advisors, Inc. | 581,793 | $925.0K | 0.00% | −594−0.1% | Reduced |
| Charles Schwab Investment Management Inc | 555,628 | $883.4K | 0.00% | −2,846−0.5% | Reduced |
| Citadel Advisors LLC | 515,429 | $819.5K | 0.00% | +250,306+94.4% | Added |
| Goldman Sachs Group Inc | 489,138 | $777.7K | 0.00% | +244,314+99.8% | Added |
| 72 Investment Holdings, LLC | 474,067 | $753.8K | 1.49% | 00.0% | Unchanged |
| State Street Corp | 423,263 | $673.0K | 0.00% | +37,000+9.6% | Added |
| XTX Topco Ltd | 413,380 | $657.3K | 0.02% | −28,161−6.4% | Reduced |
| Point72 Asset Management, L.P. | 403,938 | $642.3K | 0.00% | +115,391+40.0% | Added |
| Green Alpha Advisors, LLC | 375,139 | $596.5K | 0.55% | +11,440+3.1% | Added |
| Gsa Capital Partners LLP | 371,372 | $590.0K | 0.05% | +371,372 | New |
| Morgan Stanley | 298,456 | $474.5K | 0.00% | −59,763−16.7% | Reduced |
| Jane Street Group, LLC | 295,685 | $470.1K | 0.00% | −183,753−38.3% | Reduced |
| Bruce & Co., Inc. | 250,000 | $397.5K | 0.12% | 00.0% | Unchanged |
| Milestone Asset Management, LLC | 231,799 | $368.6K | 0.07% | +55,832+31.7% | Added |
| Northern Trust Corp | 217,735 | $346.2K | 0.00% | +12,663+6.2% | Added |
| Qube Research & Technologies Ltd | 204,652 | $325.4K | 0.00% | +159,502+353.3% | Added |
| Omers Administration Corp | 178,100 | $283.2K | 0.00% | +178,100 | New |
| Quadrature Capital Ltd | 159,317 | $253.3K | 0.00% | +159,317 | New |
| Bridgeway Capital Management, LLC | 148,500 | $236.1K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 141,943 | $225.7K | 0.00% | +116,089+449.0% | Added |
| Nano Cap New Millennium Growth Fund L P | 112,500 | $178.9K | 0.15% | +112,500 | New |
| American Century Companies Inc | 112,453 | $178.8K | 0.00% | +30,651+37.5% | Added |
| Graham Capital Management, L.P. | 107,253 | $170.5K | 0.01% | −21,099−16.4% | Reduced |
| Siren, L.L.C. | 105,347 | $167.5K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 85,246 | $135.5K | 0.00% | +85,246 | New |
| Ameriprise Financial Inc | 85,104 | $135.3K | 0.00% | −250−0.3% | Reduced |
| Keystone Financial Group | 80,475 | $128.0K | 0.01% | +80,475 | New |
| ExodusPoint Capital Management, LP | 77,704 | $123.5K | 0.00% | +77,704 | New |
| Citigroup Inc | 74,571 | $118.6K | 0.00% | +73,000+4,646.7% | Added |
| Acadian Asset Management LLC | 59,722 | $94.0K | 0.00% | +59,722 | New |
| Nelson Capital Management, LLC | 58,685 | $93.3K | 0.01% | −26,335−31.0% | Reduced |
| Squarepoint Ops LLC | 55,938 | $88.9K | 0.00% | +31,828+132.0% | Added |
| Commonwealth Equity Services, LLC | 45,908 | $73.0K | 0.00% | −1,025−2.2% | Reduced |
| Jefferies Financial Group Inc. | 44,840 | $71.3K | 0.00% | −2,360−5.0% | Reduced |
| Lighthouse Investment Partners, LLC | 44,160 | $70.2K | 0.00% | +44,160 | New |
| Public Employees Retirement System of Ohio | 42,229 | $67.1K | 0.00% | 00.0% | Unchanged |
| JustInvest LLC | 42,113 | $67.0K | 0.00% | −73−0.2% | Reduced |
| RBF Capital, LLC | 40,000 | $63.6K | 0.00% | −40,000−50.0% | Reduced |
| Man Group plc | 36,712 | $58.4K | 0.00% | +36,712 | New |
| Wiley Bros.-Aintree Capital, LLC | 35,505 | $56.5K | 0.00% | −8,634−19.6% | Reduced |
| Invesco Ltd. | 35,063 | $55.8K | 0.00% | +22,856+187.2% | Added |
| HSBC Holdings PLC | 34,460 | $55.0K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 34,265 | $54.5K | 0.00% | 00.0% | Unchanged |
| Prime Capital Investment Advisors, LLC | 33,934 | $54.0K | 0.00% | −740−2.1% | Reduced |
| Envestnet Asset Management Inc | 32,307 | $51.4K | 0.00% | −6,461−16.7% | Reduced |
| Thrive Wealth Management, LLC | 32,000 | $50.9K | 0.01% | 00.0% | Unchanged |
| Credit Agricole S A | 29,000 | $46.1K | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 25,561 | $40.6K | 0.00% | −35,846−58.4% | Reduced |
| Russell Investments Group, Ltd. | 24,347 | $38.7K | 0.00% | +10,824+80.0% | Added |
| Barclays PLC | 21,688 | $34.5K | 0.00% | −84−0.4% | Reduced |
| Tower Research Capital LLC (TRC) | 20,351 | $32.4K | 0.00% | +1,132+5.9% | Added |
| Next Capital Management LLC | 20,000 | $31.8K | 0.01% | 00.0% | Unchanged |
| Liberty Wealth Management LLC | 19,500 | $31.0K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 18,500 | $29.4K | 0.00% | −422−2.2% | Reduced |
| HighTower Advisors, LLC | 16,934 | $26.9K | 0.00% | 00.0% | Unchanged |
| Cetera Investment Advisers | 15,781 | $25.1K | 0.00% | +898+6.0% | Added |
| Bronte Capital Management Pty Ltd. | 15,627 | $24.8K | 0.00% | +15,627 | New |
| LPL Financial LLC | 15,524 | $24.7K | 0.00% | +5,228+50.8% | Added |
| China Universal Asset Management Co., Ltd. | 15,231 | $24.2K | 0.00% | +15,231 | New |
| Royal Bank of Canada | 14,874 | $24.0K | 0.00% | −559,393−97.4% | Reduced |
| Modern Wealth Management, LLC | 15,000 | $23.9K | 0.00% | +5,000+50.0% | Added |
| Bank of New York Mellon Corp | 12,956 | $20.6K | 0.00% | −1,095−7.8% | Reduced |
| Pinnacle Associates Ltd | 12,903 | $20.5K | 0.00% | 00.0% | Unchanged |
| Pinnacle Wealth Management Advisory Group, LLC | 12,903 | $20.5K | 0.00% | 00.0% | Unchanged |
| Capital Advisory Group Advisory Services, LLC | 12,314 | $19.6K | 0.01% | 00.0% | Unchanged |
| Buckingham Strategic Partners | 12,216 | $19.4K | 0.00% | −35−0.3% | Reduced |
| HBK Sorce Advisory LLC | 12,344 | $19.4K | 0.00% | 00.0% | Unchanged |
| J.W. Cole Advisors, Inc. | 11,269 | $17.9K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 10,693 | $17.0K | 0.00% | +1,359+14.6% | Added |
| GWM Advisors LLC | 10,400 | $16.5K | 0.00% | 00.0% | Unchanged |
| Chevy Chase Trust Holdings, Inc. | 10,000 | $15.9K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 9,430 | $15.0K | 0.00% | +9,430 | New |
| Canada Pension Plan Investment Board | 7,400 | $11.8K | 0.00% | +7,400 | New |
| JPMorgan Chase & Co | 6,601 | $10.5K | 0.00% | +6,601 | New |
| Mirae Asset Global Investments Co., Ltd. | 4,542 | $7.22K | 0.00% | +4,542 | New |
| The PNC Financial Services Group, Inc. | 4,422 | $7.03K | 0.00% | −6−0.1% | Reduced |
| Larson Financial Group LLC | 4,066 | $6.46K | 0.00% | +4,066 | New |
| Atlantic Union Bankshares Corp | 3,200 | $5.09K | 0.00% | 00.0% | Unchanged |
| Hilton Head Capital Partners, LLC | 3,000 | $4.77K | 0.00% | +3,000 | New |
| Federated Hermes, Inc. | 2,722 | $4.33K | 0.00% | −344−11.2% | Reduced |
| Nvest Wealth Strategies, Inc. | 2,525 | $4.01K | 0.00% | +2,525 | New |