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Caribou Biosciences, Inc.

CRBU
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001619856

No open-market purchases or sales by Caribou Biosciences, Inc. insiders were filed in the last 90 days; 137 institutions reported holding it in 13F filings for Q2 2026, worth $84.8M in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q3 2025

Institutional positions in Caribou Biosciences, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
117
−12 vs. Q2 2025
Shares held
37.2M
−3.61M (−8.8%) vs. Q2 2025
Total value
$87.0M
+$35.8M (+69.9%) vs. Q2 2025
New holders
16
21 more added
Sold out
28
47 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CRBU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 117 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 88 institutionsQ4 2021: 93 institutionsQ1 2022: 104 institutionsQ2 2022: 120 institutionsQ3 2022: 113 institutionsQ4 2022: 133 institutionsQ1 2023: 126 institutionsQ2 2023: 121 institutionsQ3 2023: 126 institutionsQ4 2023: 144 institutionsQ1 2024: 151 institutionsQ2 2024: 140 institutionsQ3 2024: 129 institutionsQ4 2024: 133 institutionsQ1 2025: 131 institutionsQ2 2025: 129 institutionsQ3 2025: 117 institutionsQ4 2025: 124 institutionsQ1 2026: 137 institutionsQ2 2026: 137 institutions
Value heldQ3 2025: $87.0M
Q1 2021: $0Q2 2021: $0Q3 2021: $704.7MQ4 2021: $464.7MQ1 2022: $313.2MQ2 2022: $203.0MQ3 2022: $456.8MQ4 2022: $273.8MQ1 2023: $238.3MQ2 2023: $185.5MQ3 2023: $338.5MQ4 2023: $395.8MQ1 2024: $343.0MQ2 2024: $87.6MQ3 2024: $103.1MQ4 2024: $93.1MQ1 2025: $45.8MQ2 2025: $51.2MQ3 2025: $87.0MQ4 2025: $58.8MQ1 2026: $71.3MQ2 2026: $84.8M
Institutions holding CRBU and their total value by quarter
QuarterHoldersValue
Q2 2026137$84.8M
Q1 2026137$71.3M
Q4 2025124$58.8M
Q3 2025117$87.0M
Q2 2025129$51.2M
Q1 2025131$45.8M
Q4 2024133$93.1M
Q3 2024129$103.1M
Q2 2024140$87.6M
Q1 2024151$343.0M
Q4 2023144$395.8M
Q3 2023126$338.5M
Q2 2023121$185.5M
Q1 2023126$238.3M
Q4 2022133$273.8M
Q3 2022113$456.8M
Q2 2022120$203.0M
Q1 2022104$313.2M
Q4 202193$464.7M
Q3 202188$704.7M
Q2 20210$0
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Caribou Biosciences, Inc.; share changes are against Q2 2025.

Institutions holding CRBU in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Pfizer Inc4,690,431$10.9M2.50%00.0%Unchanged
Vanguard Group Inc4,226,926$9.85M0.00%+137,060+3.4%Added
Millennium Management LLC3,216,535$7.49M0.01%+1,665,946+107.4%Added
Kynam Capital Management, LP3,067,774$7.15M0.53%00.0%Unchanged
BlackRock, Inc.1,459,320$3.40M0.00%−424,156−22.5%Reduced
Standard Life Aberdeen plc1,388,905$3.24M0.01%+491,326+54.7%Added
PFM Health Sciences, LP1,358,831$3.17M0.27%00.0%Unchanged
Two Sigma Advisers, LP1,227,400$2.86M0.01%−220,400−15.2%Reduced
Dimensional Fund Advisors LP1,210,310$2.82M0.00%−97,045−7.4%Reduced
Bank of America Corp1,074,442$2.50M0.00%+265,542+32.8%Added
Geode Capital Management, LLC985,126$2.30M0.00%+4,197+0.4%Added
Two Sigma Investments, LP783,590$1.83M0.00%−144,935−15.6%Reduced
Renaissance Technologies LLC780,421$1.82M0.00%+248,300+46.7%Added
Pale Fire Capital SE775,055$1.81M0.20%00.0%Unchanged
FMR LLC729,002$1.70M0.00%−439−0.1%Reduced
Maverick Capital LtdSuperinvestorMaverick Capital652,542$1.52M0.02%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.582,387$1.36M0.00%−2,059−0.4%Reduced
Royal Bank of Canada574,267$1.34M0.00%−24,964−4.2%Reduced
Schonfeld Strategic Advisors LLC558,576$1.30M0.01%−1,714,290−75.4%Reduced
Charles Schwab Investment Management Inc558,474$1.30M0.00%+29,025+5.5%Added
Jane Street Group, LLC479,438$1.12M0.00%−4,172−0.9%Reduced
72 Investment Holdings, LLC474,067$1.10M1.63%00.0%Unchanged
Susquehanna International Group, LLP445,607$1.04M0.00%+180,972+68.4%Added
XTX Topco Ltd441,541$1.03M0.05%+336,308+319.6%Added
State Street Corp386,263$900.0K0.00%+28,100+7.8%Added
Green Alpha Advisors, LLC363,699$847.4K0.82%−61,980−14.6%Reduced
Morgan Stanley358,219$834.6K0.00%+26,738+8.1%Added
Jacobs Levy Equity Management, Inc349,083$813.4K0.00%−607,897−63.5%Reduced
UBS Group AG319,292$744.0K0.00%+70,189+28.2%Added
DekaBank Deutsche Girozentrale130,000$716.0K0.00%00.0%Unchanged
Point72 Asset Management, L.P.288,547$672.3K0.00%−1,192−0.4%Reduced
Citadel Advisors LLC265,123$617.7K0.00%+24,904+10.4%Added
Bruce & Co., Inc.250,000$582.5K0.18%00.0%Unchanged
Goldman Sachs Group Inc244,824$570.4K0.00%−546,792−69.1%Reduced
Northern Trust Corp205,072$477.8K0.00%−6,916−3.3%Reduced
Milestone Asset Management, LLC175,967$410.0K0.08%−233,595−57.0%Reduced
Bridgeway Capital Management, LLC148,500$346.0K0.01%00.0%Unchanged
Graham Capital Management, L.P.128,352$299.1K0.01%+128,352New
Marshall Wace, LLP125,844$293.2K0.00%+125,844New
Siren, L.L.C.105,347$245.5K0.01%00.0%Unchanged
Cubist Systematic Strategies, LLC92,762$216.1K0.00%−215,239−69.9%Reduced
Catalyst Funds Management Pty Ltd88,300$205.7K0.03%+49,600+128.2%Added
Ameriprise Financial Inc85,354$198.9K0.00%−223,601−72.4%Reduced
Nelson Capital Management, LLC85,020$198.1K0.02%00.0%Unchanged
American Century Companies Inc81,802$190.6K0.00%+81,802New
RBF Capital, LLC80,000$186.4K0.01%00.0%Unchanged
AQR Capital Management LLC61,407$143.1K0.00%−585,718−90.5%Reduced
Jefferies Financial Group Inc.47,200$110.0K0.00%+47,200New
Commonwealth Equity Services, LLC46,933$109.0K0.00%−13,031−21.7%Reduced
Qube Research & Technologies Ltd45,150$105.2K0.00%+45,150New
Wiley Bros.-Aintree Capital, LLC44,139$102.8K0.00%−292,426−86.9%Reduced
Public Employees Retirement System of Ohio42,229$98.4K0.00%−86,200−67.1%Reduced
JustInvest LLC42,186$98.3K0.00%+1,373+3.4%Added
Envestnet Asset Management Inc38,768$90.3K0.00%−279,889−87.8%Reduced
Thrivent Financial for Lutherans35,562$83.0K0.00%−238,923−87.0%Reduced
Prime Capital Investment Advisors, LLC34,674$80.8K0.00%−3,319−8.7%Reduced
US Bancorp34,265$79.8K0.00%+34,082+18,624.0%Added
HSBC Holdings PLC34,460$78.2K0.00%−80,183−69.9%Reduced
Thrive Wealth Management, LLC32,000$74.6K0.01%00.0%Unchanged
Susquehanna Portfolio Strategies, LLC29,883$69.6K0.00%+29,883New
Point72 Asia (Singapore) Pte. Ltd.29,658$69.1K0.01%−29,880−50.2%Reduced
Credit Agricole S A29,000$67.6K0.00%+29,000New
Wells Fargo & Company25,854$60.2K0.00%−61,898−70.5%Reduced
Squarepoint Ops LLC24,110$56.2K0.00%−5,619−18.9%Reduced
Barclays PLC21,772$50.7K0.00%+84+0.4%Added
Simplex Trading, LLC21,123$49.0K0.00%+21,123New
Next Capital Management LLC20,000$46.6K0.02%00.0%Unchanged
Liberty Wealth Management LLC19,500$45.4K0.01%+19,500New
Tower Research Capital LLC (TRC)19,219$44.8K0.00%−54,834−74.0%Reduced
Creative Planning18,922$44.1K0.00%−1,249−6.2%Reduced
HighTower Advisors, LLC16,934$39.5K0.00%−200−1.2%Reduced
HBK Sorce Advisory LLC12,344$35.1K0.00%00.0%Unchanged
Cetera Investment Advisers14,883$34.7K0.00%+2,229+17.6%Added
Bank of New York Mellon Corp14,051$32.7K0.00%+38+0.3%Added
Russell Investments Group, Ltd.13,523$31.5K0.00%−9,049−40.1%Reduced
Pinnacle Associates Ltd12,903$30.1K0.00%00.0%Unchanged
Pinnacle Wealth Management Advisory Group, LLC12,903$30.1K0.00%00.0%Unchanged
Capital Advisory Group Advisory Services, LLC12,314$28.7K0.01%+814+7.1%Added
R Squared Ltd12,268$28.6K0.01%+12,268New
Buckingham Strategic Partners12,251$28.5K0.00%−3,344−21.4%Reduced
Invesco Ltd.12,207$28.4K0.00%−12,532−50.7%Reduced
J.W. Cole Advisors, Inc.11,269$26.3K0.00%−735−6.1%Reduced
GWM Advisors LLC10,400$24.2K0.00%00.0%Unchanged
LPL Financial LLC10,296$24.0K0.00%+10,296New
Chevy Chase Trust Holdings, Inc.10,000$23.3K0.00%00.0%Unchanged
Modern Wealth Management, LLC10,000$23.3K0.00%00.0%Unchanged
FSA Wealth Management LLC8,630$20.1K0.01%00.0%Unchanged
Advisor Group Holdings, Inc.9,334$18.7K0.00%+500+5.7%Added
Wealthspire Advisors, LLC7,500$17.5K0.00%+7,500New
Group One Trading, L.P.6,084$14.2K0.00%−19,831−76.5%Reduced
The PNC Financial Services Group, Inc.4,428$10.3K0.00%00.0%Unchanged
Atlantic Union Bankshares Corp3,200$7.46K0.00%+3,200New
Federated Hermes, Inc.3,066$7.14K0.00%−4,851−61.3%Reduced
CWM, LLC2,435$6.00K0.00%−31,404−92.8%Reduced
Newbridge Financial Services Group, Inc.2,000$4.66K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA1,876$4.37K0.00%−17,487−90.3%Reduced
Citigroup Inc1,571$3.66K0.00%−29,790−95.0%Reduced
Optiver Holding B.V.1,104$2.57K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC1,026$2.39K0.00%00.0%Unchanged
Harbour Investments, Inc.1,000$2.33K0.00%00.0%Unchanged