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Caribou Biosciences, Inc.

CRBU
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001619856

No open-market purchases or sales by Caribou Biosciences, Inc. insiders were filed in the last 90 days; 137 institutions reported holding it in 13F filings for Q2 2026, worth $84.8M in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q1 2026

Institutional positions in Caribou Biosciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
137
+15 vs. Q4 2025
Shares held
37.8M
+5.01M (+15.3%) vs. Q4 2025
Total value
$71.3M
+$19.3M (+37.2%) vs. Q4 2025
New holders
28
27 more added
Sold out
13
39 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CRBU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 137 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 88 institutionsQ4 2021: 93 institutionsQ1 2022: 104 institutionsQ2 2022: 120 institutionsQ3 2022: 113 institutionsQ4 2022: 133 institutionsQ1 2023: 126 institutionsQ2 2023: 121 institutionsQ3 2023: 126 institutionsQ4 2023: 144 institutionsQ1 2024: 151 institutionsQ2 2024: 140 institutionsQ3 2024: 129 institutionsQ4 2024: 133 institutionsQ1 2025: 131 institutionsQ2 2025: 129 institutionsQ3 2025: 117 institutionsQ4 2025: 124 institutionsQ1 2026: 137 institutionsQ2 2026: 137 institutions
Value heldQ1 2026: $71.3M
Q1 2021: $0Q2 2021: $0Q3 2021: $704.7MQ4 2021: $464.7MQ1 2022: $313.2MQ2 2022: $203.0MQ3 2022: $456.8MQ4 2022: $273.8MQ1 2023: $238.3MQ2 2023: $185.5MQ3 2023: $338.5MQ4 2023: $395.8MQ1 2024: $343.0MQ2 2024: $87.6MQ3 2024: $103.1MQ4 2024: $93.1MQ1 2025: $45.8MQ2 2025: $51.2MQ3 2025: $87.0MQ4 2025: $58.8MQ1 2026: $71.3MQ2 2026: $84.8M
Institutions holding CRBU and their total value by quarter
QuarterHoldersValue
Q2 2026137$84.8M
Q1 2026137$71.3M
Q4 2025124$58.8M
Q3 2025117$87.0M
Q2 2025129$51.2M
Q1 2025131$45.8M
Q4 2024133$93.1M
Q3 2024129$103.1M
Q2 2024140$87.6M
Q1 2024151$343.0M
Q4 2023144$395.8M
Q3 2023126$338.5M
Q2 2023121$185.5M
Q1 2023126$238.3M
Q4 2022133$273.8M
Q3 2022113$456.8M
Q2 2022120$203.0M
Q1 2022104$313.2M
Q4 202193$464.7M
Q3 202188$704.7M
Q2 20210$0
Q1 20210$0

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Caribou Biosciences, Inc.; share changes are against Q4 2025.

Institutions holding CRBU in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Pfizer Inc4,690,431$8.35M3.50%00.0%Unchanged
Vanguard Capital Management LLC3,767,228$7.16M0.00%+3,767,228New
Renaissance Technologies LLC2,590,497$4.92M0.01%+950,640+58.0%Added
Kynam Capital Management, LP2,503,302$4.76M0.30%00.0%Unchanged
BlackRock, Inc.2,143,085$4.07M0.00%+2,062+0.1%Added
Two Sigma Investments, LP1,759,934$3.34M0.00%+739,855+72.5%Added
Bank of America Corp1,297,167$2.46M0.00%+303,981+30.6%Added
Standard Life Aberdeen plc1,212,541$2.30M0.00%−176,364−12.7%Reduced
Marshall Wace, LLP1,205,668$2.29M0.00%+324,563+36.8%Added
Millennium Management LLC1,074,421$2.04M0.00%+307,419+40.1%Added
Geode Capital Management, LLC1,017,959$1.93M0.00%+41,146+4.2%Added
PFM Health Sciences, LP957,787$1.82M0.19%00.0%Unchanged
Mackenzie Financial Corp942,786$1.79M0.00%+942,786New
Acadian Asset Management LLC925,039$1.75M0.00%+865,317+1,448.9%Added
Susquehanna International Group, LLP836,903$1.59M0.00%−194,472−18.9%Reduced
FMR LLC723,959$1.38M0.00%−2,009−0.3%Reduced
Dimensional Fund Advisors LP673,200$1.28M0.00%−332,810−33.1%Reduced
Maverick Capital LtdSuperinvestorMaverick Capital652,542$1.24M0.01%00.0%Unchanged
Charles Schwab Investment Management Inc559,642$1.06M0.00%+4,014+0.7%Added
Cambridge Investment Research Advisors, Inc.547,014$1.04M0.00%−34,779−6.0%Reduced
Vanguard Fiduciary Trust Co520,118$988.2K0.00%+520,118New
Gsa Capital Partners LLP480,724$913.0K0.06%+109,352+29.4%Added
72 Investment Holdings, LLC474,067$900.7K1.82%00.0%Unchanged
State Street Corp423,263$804.2K0.00%00.0%Unchanged
Goldman Sachs Group Inc376,589$715.5K0.00%−112,549−23.0%Reduced
Green Alpha Advisors, LLC373,650$709.9K0.70%−1,489−0.4%Reduced
Jacobs Levy Equity Management, Inc358,941$682.0K0.00%−465,358−56.5%Reduced
XTX Topco Ltd323,469$614.6K0.01%−89,911−21.8%Reduced
Wells Fargo & Company303,655$576.9K0.00%+161,712+113.9%Added
UBS Group AG259,169$492.4K0.00%−378,576−59.4%Reduced
Bruce & Co., Inc.250,000$475.0K0.14%00.0%Unchanged
Morgan Stanley245,112$465.7K0.00%−53,344−17.9%Reduced
Northern Trust Corp217,735$413.7K0.00%00.0%Unchanged
Point72 Asset Management, L.P.187,622$356.5K0.00%−216,316−53.6%Reduced
Qube Research & Technologies Ltd176,697$335.7K0.00%−27,955−13.7%Reduced
Milestone Asset Management, LLC162,076$307.9K0.06%−69,723−30.1%Reduced
Citadel Advisors LLC159,033$302.2K0.00%−356,396−69.1%Reduced
Bridgeway Capital Management, LLC132,000$250.8K0.01%−16,500−11.1%Reduced
Omers Administration Corp120,200$228.4K0.00%−57,900−32.5%Reduced
Nano Cap New Millennium Growth Fund L P117,500$223.3K0.21%+5,000+4.4%Added
American Century Companies Inc112,453$213.7K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.88,487$168.1K0.00%+3,241+3.8%Added
Invesco Ltd.83,502$158.7K0.00%+48,439+138.1%Added
Keystone Financial Group80,475$152.9K0.01%00.0%Unchanged
HRT Financial LP78,954$150.0K0.00%+78,954New
Man Group plc77,210$146.7K0.00%+40,498+110.3%Added
Brevan Howard Capital Management LP65,062$123.6K0.00%+65,062New
Nelson Capital Management, LLC58,685$111.5K0.01%00.0%Unchanged
Canada Pension Plan Investment Board57,900$110.0K0.00%+50,500+682.4%Added
Citigroup Inc56,923$108.2K0.00%−17,648−23.7%Reduced
Commonwealth Equity Services, LLC44,908$85.3K0.00%−1,000−2.2%Reduced
RBF Capital, LLC40,000$76.0K0.00%00.0%Unchanged
Quadrature Capital Ltd39,556$75.2K0.00%−119,761−75.2%Reduced
JustInvest LLC39,233$74.5K0.00%−2,880−6.8%Reduced
Public Employees Retirement System of Ohio39,129$74.3K0.00%−3,100−7.3%Reduced
Graham Capital Management, L.P.38,751$73.6K0.00%−68,502−63.9%Reduced
Virtu Financial LLC36,609$70.0K0.00%+36,609New
LPL Financial LLC35,274$67.0K0.00%+19,750+127.2%Added
HSBC Holdings PLC34,460$65.3K0.00%00.0%Unchanged
US Bancorp34,265$65.1K0.00%00.0%Unchanged
Jefferies Financial Group Inc.33,262$63.2K0.00%−11,578−25.8%Reduced
Diametric Capital, LP32,793$62.3K0.02%+32,793New
Wiley Bros.-Aintree Capital, LLC32,505$61.8K0.00%−3,000−8.4%Reduced
Prime Capital Investment Advisors, LLC32,315$61.4K0.00%−1,619−4.8%Reduced
Catalyst Funds Management Pty Ltd32,200$61.2K0.01%+32,200New
Thrive Wealth Management, LLC32,000$60.8K0.01%00.0%Unchanged
SEI Investments Co31,008$58.9K0.00%+31,008New
Connor, Clark & Lunn Investment Management Ltd.30,741$58.4K0.00%+30,741New
Envestnet Asset Management Inc30,586$58.1K0.00%−1,721−5.3%Reduced
Ameriprise Financial Inc29,430$55.9K0.00%−55,674−65.4%Reduced
Vanguard Global Advisers, LLC29,101$55.3K0.00%+29,101New
Credit Agricole S A29,000$55.1K0.00%00.0%Unchanged
Russell Investments Group, Ltd.27,560$52.4K0.00%+3,213+13.2%Added
Barclays PLC26,713$50.8K0.00%+5,025+23.2%Added
Jane Street Group, LLC24,975$47.5K0.00%−270,710−91.6%Reduced
Schonfeld Strategic Advisors LLC23,969$45.5K0.00%+23,969New
Bank of Montreal21,000$39.9K0.00%+21,000New
Nine Masts Capital Ltd20,612$39.2K0.01%+20,612New
Next Capital Management LLC20,000$38.0K0.01%00.0%Unchanged
Westmount Partners, LLC19,609$37.3K0.01%+19,609New
Liberty Wealth Management LLC19,500$37.0K0.00%00.0%Unchanged
Prudential Financial Inc19,000$36.1K0.00%+19,000New
HighTower Advisors, LLC16,934$32.2K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.16,587$31.5K0.00%+1,356+8.9%Added
Creative Planning16,500$31.4K0.00%−2,000−10.8%Reduced
Raymond James Financial Inc16,373$31.1K0.00%+16,373New
Modern Wealth Management, LLC15,000$29.9K0.00%00.0%Unchanged
AQR Capital Management LLC15,678$29.8K0.00%−9,883−38.7%Reduced
Bronte Capital Management Pty Ltd.15,627$29.7K0.00%00.0%Unchanged
CTC Alternative Strategies, Ltd.15,076$28.6K0.07%+15,076New
Axq Capital, LP15,000$28.5K0.00%+15,000New
Cetera Investment Advisers14,781$28.1K0.00%−1,000−6.3%Reduced
Great Valley Advisor Group, Inc.14,314$27.6K0.00%+14,314New
Two Sigma Securities, LLC13,052$24.8K0.00%+13,052New
Pinnacle Associates Ltd12,903$24.5K0.00%00.0%Unchanged
Pinnacle Wealth Management Advisory Group, LLC12,903$24.5K0.00%00.0%Unchanged
HBK Sorce Advisory LLC12,344$23.9K0.00%00.0%Unchanged
Bank of New York Mellon Corp12,511$23.8K0.00%−445−3.4%Reduced
Jump Financial, LLC12,460$23.7K0.00%+12,460New
GWM Advisors LLC10,925$20.8K0.00%+525+5.0%Added