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Caribou Biosciences, Inc.

CRBU
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001619856

No open-market purchases or sales by Caribou Biosciences, Inc. insiders were filed in the last 90 days; 137 institutions reported holding it in 13F filings for Q2 2026, worth $84.8M in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q4 2021

Institutional positions in Caribou Biosciences, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
93
+5 vs. Q3 2021
Shares held
31.1M
+1.00M (+3.3%) vs. Q3 2021
Total value
$464.7M
−$240.0M (−34.1%) vs. Q3 2021
New holders
27
32 more added
Sold out
22
11 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CRBU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 93 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 88 institutionsQ4 2021: 93 institutionsQ1 2022: 104 institutionsQ2 2022: 120 institutionsQ3 2022: 113 institutionsQ4 2022: 133 institutionsQ1 2023: 126 institutionsQ2 2023: 121 institutionsQ3 2023: 126 institutionsQ4 2023: 144 institutionsQ1 2024: 151 institutionsQ2 2024: 140 institutionsQ3 2024: 129 institutionsQ4 2024: 133 institutionsQ1 2025: 131 institutionsQ2 2025: 129 institutionsQ3 2025: 117 institutionsQ4 2025: 124 institutionsQ1 2026: 137 institutionsQ2 2026: 137 institutions
Value heldQ4 2021: $464.7M
Q1 2021: $0Q2 2021: $0Q3 2021: $704.7MQ4 2021: $464.7MQ1 2022: $313.2MQ2 2022: $203.0MQ3 2022: $456.8MQ4 2022: $273.8MQ1 2023: $238.3MQ2 2023: $185.5MQ3 2023: $338.5MQ4 2023: $395.8MQ1 2024: $343.0MQ2 2024: $87.6MQ3 2024: $103.1MQ4 2024: $93.1MQ1 2025: $45.8MQ2 2025: $51.2MQ3 2025: $87.0MQ4 2025: $58.8MQ1 2026: $71.3MQ2 2026: $84.8M
Institutions holding CRBU and their total value by quarter
QuarterHoldersValue
Q2 2026137$84.8M
Q1 2026137$71.3M
Q4 2025124$58.8M
Q3 2025117$87.0M
Q2 2025129$51.2M
Q1 2025131$45.8M
Q4 2024133$93.1M
Q3 2024129$103.1M
Q2 2024140$87.6M
Q1 2024151$343.0M
Q4 2023144$395.8M
Q3 2023126$338.5M
Q2 2023121$185.5M
Q1 2023126$238.3M
Q4 2022133$273.8M
Q3 2022113$456.8M
Q2 2022120$203.0M
Q1 2022104$313.2M
Q4 202193$464.7M
Q3 202188$704.7M
Q2 20210$0
Q1 20210$0

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Caribou Biosciences, Inc.; share changes are against Q3 2021.

Institutions holding CRBU in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
PFM Health Sciences, LP4,092,309$59.4M2.07%00.0%Unchanged
FMR LLC3,323,284$50.1M0.00%00.0%Unchanged
Farallon Capital Management, L.L.C.2,963,448$44.7M0.25%00.0%Unchanged
Avidity Partners Management LP2,674,067$40.4M0.86%+200,000+8.1%Added
Pictet Asset Management SA1,916,431$28.9M0.03%−48,276−2.5%Reduced
BlackRock Inc.1,763,029$26.6M0.00%+581,489+49.2%Added
Alkeon Capital Management LLC1,246,625$18.8M0.06%00.0%Unchanged
Janus Henderson Group PLC1,172,725$16.7M0.01%−66,927−5.4%Reduced
Vanguard Group Inc914,516$13.8M0.00%−21,884−2.3%Reduced
FIL Ltd860,667$13.0M0.01%00.0%Unchanged
Memorial Sloan Kettering Cancer Center674,196$10.2M6.39%00.0%Unchanged
Tekla Capital Management LLC699,377$9.88M0.32%00.0%Unchanged
Maverick Capital LtdSuperinvestorMaverick Capital652,542$9.75M0.12%−300,000−31.5%Reduced
Adage Capital Partners GP, L.L.C.609,067$9.19M0.02%00.0%Unchanged
Rokos Capital Management LLP570,359$8.60M1.71%+220,386+63.0%Added
Coatue Management LLCSuperinvestorCoatue Management557,669$8.41M0.04%−142,331−20.3%Reduced
Monashee Investment Management LLC504,377$7.61M1.88%+55,000+12.2%Added
72 Investment Holdings, LLC474,067$7.15M6.35%00.0%Unchanged
CloudAlpha Capital Management Limited/Hong Kong415,000$6.26M7.34%+110,000+36.1%Added
State Street Corp412,948$6.23M0.00%+129,359+45.6%Added
Artal Group S.A.405,347$6.12M0.18%00.0%Unchanged
Geode Capital Management, LLC361,632$5.46M0.00%+19,417+5.7%Added
Point72 Asset Management, L.P.289,739$4.37M0.02%00.0%Unchanged
Duquesne Family Office LLCSuperinvestorDuquesne Family Office271,430$4.10M0.15%00.0%Unchanged
Millennium Management LLC257,500$3.89M0.00%+182,826+244.8%Added
Velan Capital Investment Management LP210,695$3.18M2.66%+210,695New
Northern Trust Corp184,087$2.78M0.00%+11,086+6.4%Added
Shelton Capital Management182,000$2.75M0.10%+44,000+31.9%Added
Mirae Asset Global Investments Co., Ltd.178,913$2.70M0.01%+178,913New
Citadel Advisors LLC151,110$2.28M0.00%+151,110New
Charles Schwab Investment Management Inc142,516$2.15M0.00%+9,239+6.9%Added
D. E. Shaw & Co., Inc.141,361$2.13M0.00%+141,361New
Laurion Capital Management LP115,000$1.74M0.03%00.0%Unchanged
Morgan Stanley103,068$1.56M0.00%+50,312+95.4%Added
Renaissance Technologies LLC95,949$1.45M0.00%+95,949New
Bank of America Corp90,142$1.36M0.00%+55,767+162.2%Added
Granahan Investment Management Inc82,127$1.24M0.03%−59,824−42.1%Reduced
Victory Capital Management Inc81,160$1.23M0.00%−3,770−4.4%Reduced
Squarepoint Ops LLC76,691$1.16M0.01%+1,691+2.3%Added
EcoR1 Capital, LLC75,000$1.13M0.04%00.0%Unchanged
Woodline Partners LP68,802$1.04M0.02%−50,471−42.3%Reduced
Bank of New York Mellon Corp67,835$1.02M0.00%+19,704+40.9%Added
Stansberry Asset Management, LLC67,371$1.02M0.19%+40,047+146.6%Added
Nuveen Asset Management, LLC62,781$1.01M0.00%−3,007−4.6%Reduced
Ensign Peak Advisors, Inc64,788$978.0K0.00%+64,788New
Vident Investment Advisory, LLC60,306$910.0K0.02%+60,306New
Swiss National Bank52,800$797.0K0.00%+52,800New
Pura Vida Investments, LLC41,932$633.0K0.07%−1,707−3.9%Reduced
Ergoteles LLC41,487$626.0K0.02%+41,487New
Green Alpha Advisors, LLC35,592$537.0K0.36%+2,756+8.4%Added
Goldman Sachs Group Inc31,723$478.0K0.00%+31,723New
California State Teachers Retirement System31,489$475.0K0.00%+21,128+203.9%Added
Citigroup Inc30,496$460.0K0.00%+28,271+1,270.6%Added
Tudor Investment Corp Et Al30,021$453.0K0.01%+30,021New
Wells Fargo & Company26,060$394.0K0.00%+24,758+1,901.5%Added
State of Wisconsin Investment Board25,100$379.0K0.00%+25,100New
Allspring Global Investments Holdings, LLC22,163$334.0K0.00%+22,163New
New York State Common Retirement Fund21,447$324.0K0.00%+4,086+23.5%Added
DekaBank Deutsche Girozentrale22,000$321.0K0.00%+22,000New
Rhumbline Advisers19,725$298.0K0.00%+2,126+12.1%Added
JPMorgan Chase & Co18,066$273.0K0.00%+11,002+155.7%Added
UBS Group AG17,934$271.0K0.00%+8,976+100.2%Added
Credit Suisse AG16,463$247.0K0.00%+16,463New
Atom Investors LP16,323$246.0K0.07%+16,323New
AlphaCentric Advisors LLC16,000$241.0K0.07%+16,000New
Susquehanna International Group, LLP14,463$218.0K0.00%+14,463New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.13,922$213.0K0.00%+13,922New
Deutsche Bank AG13,014$196.0K0.00%+1,296+11.1%Added
Royce & Associates LP12,900$195.0K0.00%+12,900New
ProShare Advisors LLC12,910$195.0K0.00%+12,910New
KCL Capital, L.P.12,000$181.0K0.02%+2,856+31.2%Added
Manufacturers Life Insurance Company, The10,912$165.0K0.00%+1,165+12.0%Added
American International Group, Inc.10,776$163.0K0.00%+280+2.7%Added
LMR Partners LLP10,000$151.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC9,949$150.0K0.06%+9,949New
Legal & General Group Plc8,153$123.0K0.00%+6,355+353.4%Added
MetLife Investment Management7,531$113.6K0.00%00.0%Unchanged
Metropolitan Life Insurance Co5,697$86.0K0.00%00.0%Unchanged
STRS Ohio4,400$66.0K0.00%00.0%Unchanged
Simplex Trading, LLC4,106$61.0K0.00%+4,106New
Royal Bank of Canada3,758$58.0K0.00%+1,000+36.3%Added
Tower Research Capital LLC (TRC)2,660$40.0K0.00%+2,190+466.0%Added
Ameritas Investment Partners, Inc.1,470$22.0K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC1,100$17.0K0.00%−9,297−89.4%Reduced
Advisor Group Holdings, Inc.896$14.0K0.00%+19+2.2%Added
Eaton Vance Management425$6.00K0.00%+425New
Daiwa Securities Group Inc.176$3.00K0.00%+176New
Piscataqua Savings Bank150$2.00K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.100$2.00K0.00%00.0%Unchanged
TCI Wealth Advisors, Inc.100$2.00K0.00%00.0%Unchanged
Retirement Group, LLC100$2.00K0.00%00.0%Unchanged
State of Wyoming159$2.00K0.00%+159New
TD Waterhouse Canada Inc.30$4330.00%+30New
Jennison Associates LLC0$00.00%−322,091−100.0%Sold out
Sphera Funds Management Ltd.0$00.00%−200,000−100.0%Sold out
Davidson Kempner Capital Management LP0$00.00%−183,600−100.0%Sold out
ArrowMark Colorado Holdings LLC0$00.00%−125,000−100.0%Sold out
Caas Capital Management LP0$00.00%−100,000−100.0%Sold out
Mark Asset Management LP0$00.00%−80,000−100.0%Sold out
Ghisallo Capital Management LLC0$00.00%−75,000−100.0%Sold out