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Caribou Biosciences, Inc.

CRBU
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001619856

No open-market purchases or sales by Caribou Biosciences, Inc. insiders were filed in the last 90 days; 137 institutions reported holding it in 13F filings for Q2 2026, worth $84.8M in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q4 2021

Institutional positions in Caribou Biosciences, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
93
+5 vs. Q3 2021
Shares held
31.1M
+1.00M (+3.3%) vs. Q3 2021
Total value
$464.7M
−$240.0M (−34.1%) vs. Q3 2021
New holders
27
32 more added
Sold out
22
11 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CRBU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 93 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 88 institutionsQ4 2021: 93 institutionsQ1 2022: 104 institutionsQ2 2022: 120 institutionsQ3 2022: 113 institutionsQ4 2022: 133 institutionsQ1 2023: 126 institutionsQ2 2023: 121 institutionsQ3 2023: 126 institutionsQ4 2023: 144 institutionsQ1 2024: 151 institutionsQ2 2024: 140 institutionsQ3 2024: 129 institutionsQ4 2024: 133 institutionsQ1 2025: 131 institutionsQ2 2025: 129 institutionsQ3 2025: 117 institutionsQ4 2025: 124 institutionsQ1 2026: 137 institutionsQ2 2026: 137 institutions
Value heldQ4 2021: $464.7M
Q1 2021: $0Q2 2021: $0Q3 2021: $704.7MQ4 2021: $464.7MQ1 2022: $313.2MQ2 2022: $203.0MQ3 2022: $456.8MQ4 2022: $273.8MQ1 2023: $238.3MQ2 2023: $185.5MQ3 2023: $338.5MQ4 2023: $395.8MQ1 2024: $343.0MQ2 2024: $87.6MQ3 2024: $103.1MQ4 2024: $93.1MQ1 2025: $45.8MQ2 2025: $51.2MQ3 2025: $87.0MQ4 2025: $58.8MQ1 2026: $71.3MQ2 2026: $84.8M
Institutions holding CRBU and their total value by quarter
QuarterHoldersValue
Q2 2026137$84.8M
Q1 2026137$71.3M
Q4 2025124$58.8M
Q3 2025117$87.0M
Q2 2025129$51.2M
Q1 2025131$45.8M
Q4 2024133$93.1M
Q3 2024129$103.1M
Q2 2024140$87.6M
Q1 2024151$343.0M
Q4 2023144$395.8M
Q3 2023126$338.5M
Q2 2023121$185.5M
Q1 2023126$238.3M
Q4 2022133$273.8M
Q3 2022113$456.8M
Q2 2022120$203.0M
Q1 2022104$313.2M
Q4 202193$464.7M
Q3 202188$704.7M
Q2 20210$0
Q1 20210$0

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Caribou Biosciences, Inc.; share changes are against Q3 2021.

Institutions holding CRBU in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
TD Waterhouse Canada Inc.30$4330.00%+30New
Piscataqua Savings Bank150$2.00K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.100$2.00K0.00%00.0%Unchanged
TCI Wealth Advisors, Inc.100$2.00K0.00%00.0%Unchanged
Retirement Group, LLC100$2.00K0.00%00.0%Unchanged
State of Wyoming159$2.00K0.00%+159New
Daiwa Securities Group Inc.176$3.00K0.00%+176New
Eaton Vance Management425$6.00K0.00%+425New
Advisor Group Holdings, Inc.896$14.0K0.00%+19+2.2%Added
Cubist Systematic Strategies, LLC1,100$17.0K0.00%−9,297−89.4%Reduced
Ameritas Investment Partners, Inc.1,470$22.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,660$40.0K0.00%+2,190+466.0%Added
Royal Bank of Canada3,758$58.0K0.00%+1,000+36.3%Added
Simplex Trading, LLC4,106$61.0K0.00%+4,106New
STRS Ohio4,400$66.0K0.00%00.0%Unchanged
Metropolitan Life Insurance Co5,697$86.0K0.00%00.0%Unchanged
MetLife Investment Management7,531$113.6K0.00%00.0%Unchanged
Legal & General Group Plc8,153$123.0K0.00%+6,355+353.4%Added
Virtus ETF Advisers LLC9,949$150.0K0.06%+9,949New
LMR Partners LLP10,000$151.0K0.00%00.0%Unchanged
American International Group, Inc.10,776$163.0K0.00%+280+2.7%Added
Manufacturers Life Insurance Company, The10,912$165.0K0.00%+1,165+12.0%Added
KCL Capital, L.P.12,000$181.0K0.02%+2,856+31.2%Added
Royce & Associates LP12,900$195.0K0.00%+12,900New
ProShare Advisors LLC12,910$195.0K0.00%+12,910New
Deutsche Bank AG13,014$196.0K0.00%+1,296+11.1%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.13,922$213.0K0.00%+13,922New
Susquehanna International Group, LLP14,463$218.0K0.00%+14,463New
AlphaCentric Advisors LLC16,000$241.0K0.07%+16,000New
Atom Investors LP16,323$246.0K0.07%+16,323New
Credit Suisse AG16,463$247.0K0.00%+16,463New
UBS Group AG17,934$271.0K0.00%+8,976+100.2%Added
JPMorgan Chase & Co18,066$273.0K0.00%+11,002+155.7%Added
Rhumbline Advisers19,725$298.0K0.00%+2,126+12.1%Added
DekaBank Deutsche Girozentrale22,000$321.0K0.00%+22,000New
New York State Common Retirement Fund21,447$324.0K0.00%+4,086+23.5%Added
Allspring Global Investments Holdings, LLC22,163$334.0K0.00%+22,163New
State of Wisconsin Investment Board25,100$379.0K0.00%+25,100New
Wells Fargo & Company26,060$394.0K0.00%+24,758+1,901.5%Added
Tudor Investment Corp Et Al30,021$453.0K0.01%+30,021New
Citigroup Inc30,496$460.0K0.00%+28,271+1,270.6%Added
California State Teachers Retirement System31,489$475.0K0.00%+21,128+203.9%Added
Goldman Sachs Group Inc31,723$478.0K0.00%+31,723New
Green Alpha Advisors, LLC35,592$537.0K0.36%+2,756+8.4%Added
Ergoteles LLC41,487$626.0K0.02%+41,487New
Pura Vida Investments, LLC41,932$633.0K0.07%−1,707−3.9%Reduced
Swiss National Bank52,800$797.0K0.00%+52,800New
Vident Investment Advisory, LLC60,306$910.0K0.02%+60,306New
Ensign Peak Advisors, Inc64,788$978.0K0.00%+64,788New
Nuveen Asset Management, LLC62,781$1.01M0.00%−3,007−4.6%Reduced
Stansberry Asset Management, LLC67,371$1.02M0.19%+40,047+146.6%Added
Bank of New York Mellon Corp67,835$1.02M0.00%+19,704+40.9%Added
Woodline Partners LP68,802$1.04M0.02%−50,471−42.3%Reduced
EcoR1 Capital, LLC75,000$1.13M0.04%00.0%Unchanged
Squarepoint Ops LLC76,691$1.16M0.01%+1,691+2.3%Added
Victory Capital Management Inc81,160$1.23M0.00%−3,770−4.4%Reduced
Granahan Investment Management Inc82,127$1.24M0.03%−59,824−42.1%Reduced
Bank of America Corp90,142$1.36M0.00%+55,767+162.2%Added
Renaissance Technologies LLC95,949$1.45M0.00%+95,949New
Morgan Stanley103,068$1.56M0.00%+50,312+95.4%Added
Laurion Capital Management LP115,000$1.74M0.03%00.0%Unchanged
D. E. Shaw & Co., Inc.141,361$2.13M0.00%+141,361New
Charles Schwab Investment Management Inc142,516$2.15M0.00%+9,239+6.9%Added
Citadel Advisors LLC151,110$2.28M0.00%+151,110New
Mirae Asset Global Investments Co., Ltd.178,913$2.70M0.01%+178,913New
Shelton Capital Management182,000$2.75M0.10%+44,000+31.9%Added
Northern Trust Corp184,087$2.78M0.00%+11,086+6.4%Added
Velan Capital Investment Management LP210,695$3.18M2.66%+210,695New
Millennium Management LLC257,500$3.89M0.00%+182,826+244.8%Added
Duquesne Family Office LLCSuperinvestorDuquesne Family Office271,430$4.10M0.15%00.0%Unchanged
Point72 Asset Management, L.P.289,739$4.37M0.02%00.0%Unchanged
Geode Capital Management, LLC361,632$5.46M0.00%+19,417+5.7%Added
Artal Group S.A.405,347$6.12M0.18%00.0%Unchanged
State Street Corp412,948$6.23M0.00%+129,359+45.6%Added
CloudAlpha Capital Management Limited/Hong Kong415,000$6.26M7.34%+110,000+36.1%Added
72 Investment Holdings, LLC474,067$7.15M6.35%00.0%Unchanged
Monashee Investment Management LLC504,377$7.61M1.88%+55,000+12.2%Added
Coatue Management LLCSuperinvestorCoatue Management557,669$8.41M0.04%−142,331−20.3%Reduced
Rokos Capital Management LLP570,359$8.60M1.71%+220,386+63.0%Added
Adage Capital Partners GP, L.L.C.609,067$9.19M0.02%00.0%Unchanged
Maverick Capital LtdSuperinvestorMaverick Capital652,542$9.75M0.12%−300,000−31.5%Reduced
Tekla Capital Management LLC699,377$9.88M0.32%00.0%Unchanged
Memorial Sloan Kettering Cancer Center674,196$10.2M6.39%00.0%Unchanged
FIL Ltd860,667$13.0M0.01%00.0%Unchanged
Vanguard Group Inc914,516$13.8M0.00%−21,884−2.3%Reduced
Janus Henderson Group PLC1,172,725$16.7M0.01%−66,927−5.4%Reduced
Alkeon Capital Management LLC1,246,625$18.8M0.06%00.0%Unchanged
BlackRock Inc.1,763,029$26.6M0.00%+581,489+49.2%Added
Pictet Asset Management SA1,916,431$28.9M0.03%−48,276−2.5%Reduced
Avidity Partners Management LP2,674,067$40.4M0.86%+200,000+8.1%Added
Farallon Capital Management, L.L.C.2,963,448$44.7M0.25%00.0%Unchanged
FMR LLC3,323,284$50.1M0.00%00.0%Unchanged
PFM Health Sciences, LP4,092,309$59.4M2.07%00.0%Unchanged
Jennison Associates LLC0$00.00%−322,091−100.0%Sold out
Sphera Funds Management Ltd.0$00.00%−200,000−100.0%Sold out
Davidson Kempner Capital Management LP0$00.00%−183,600−100.0%Sold out
ArrowMark Colorado Holdings LLC0$00.00%−125,000−100.0%Sold out
Caas Capital Management LP0$00.00%−100,000−100.0%Sold out
Mark Asset Management LP0$00.00%−80,000−100.0%Sold out
Ghisallo Capital Management LLC0$00.00%−75,000−100.0%Sold out