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Caribou Biosciences, Inc.

CRBU
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001619856

No open-market purchases or sales by Caribou Biosciences, Inc. insiders were filed in the last 90 days; 137 institutions reported holding it in 13F filings for Q2 2026, worth $84.8M in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Caribou Biosciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
124
+11 vs. Q3 2025
Shares held
37.1M
+110.9K (+0.3%) vs. Q3 2025
Total value
$58.8M
−$27.8M (−32.1%) vs. Q3 2025
New holders
25
28 more added
Sold out
14
36 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CRBU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 124 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 88 institutionsQ4 2021: 93 institutionsQ1 2022: 104 institutionsQ2 2022: 120 institutionsQ3 2022: 113 institutionsQ4 2022: 133 institutionsQ1 2023: 126 institutionsQ2 2023: 121 institutionsQ3 2023: 126 institutionsQ4 2023: 144 institutionsQ1 2024: 151 institutionsQ2 2024: 140 institutionsQ3 2024: 129 institutionsQ4 2024: 133 institutionsQ1 2025: 131 institutionsQ2 2025: 129 institutionsQ3 2025: 117 institutionsQ4 2025: 124 institutionsQ1 2026: 137 institutionsQ2 2026: 137 institutions
Value heldQ4 2025: $58.8M
Q1 2021: $0Q2 2021: $0Q3 2021: $704.7MQ4 2021: $464.7MQ1 2022: $313.2MQ2 2022: $203.0MQ3 2022: $456.8MQ4 2022: $273.8MQ1 2023: $238.3MQ2 2023: $185.5MQ3 2023: $338.5MQ4 2023: $395.8MQ1 2024: $343.0MQ2 2024: $87.6MQ3 2024: $103.1MQ4 2024: $93.1MQ1 2025: $45.8MQ2 2025: $51.2MQ3 2025: $87.0MQ4 2025: $58.8MQ1 2026: $71.3MQ2 2026: $84.8M
Institutions holding CRBU and their total value by quarter
QuarterHoldersValue
Q2 2026137$84.8M
Q1 2026137$71.3M
Q4 2025124$58.8M
Q3 2025117$87.0M
Q2 2025129$51.2M
Q1 2025131$45.8M
Q4 2024133$93.1M
Q3 2024129$103.1M
Q2 2024140$87.6M
Q1 2024151$343.0M
Q4 2023144$395.8M
Q3 2023126$338.5M
Q2 2023121$185.5M
Q1 2023126$238.3M
Q4 2022133$273.8M
Q3 2022113$456.8M
Q2 2022120$203.0M
Q1 2022104$313.2M
Q4 202193$464.7M
Q3 202188$704.7M
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Caribou Biosciences, Inc.; share changes are against Q3 2025.

Institutions holding CRBU in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
IFP Advisors, Inc1$20.00%−26−96.3%Reduced
McGuire Capital Advisors Inc10$160.00%+10New
Sunbelt Securities, Inc.18$290.00%−117−86.7%Reduced
Paladin Partners, LLC50$800.00%+50New
SRS Capital Advisors, Inc.61$970.00%−445−87.9%Reduced
SBI Securities Co., Ltd.92$1460.00%−66−41.8%Reduced
Farther Finance Advisors, LLC100$1590.00%00.0%Unchanged
Gen-Wealth Partners Inc136$2160.00%00.0%Unchanged
Signature Equity Partners, LLC177$2810.00%+177New
Jones Financial Companies LLLP200$3180.00%00.0%Unchanged
CWM, LLC575$1.00K0.00%−1,860−76.4%Reduced
Fortitude Family Office, LLC646$1.03K0.00%00.0%Unchanged
Country Trust Bank700$1.11K0.00%00.0%Unchanged
Tradewinds Capital Management, LLC800$1.27K0.00%00.0%Unchanged
Basecamp Wealth Advisors LLC937$1.49K0.00%+937New
TD Waterhouse Canada Inc.1,000$1.58K0.00%00.0%Unchanged
Harbour Investments, Inc.1,000$1.59K0.00%00.0%Unchanged
Global Retirement Partners, LLC1,000$1.59K0.00%+1,000New
Nisa Investment Advisors, LLC1,026$1.63K0.00%00.0%Unchanged
Optiver Holding B.V.1,104$1.75K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.1,835$2.92K0.00%+1,835New
BNP Paribas Arbitrage, SA1,878$2.99K0.00%+2+0.1%Added
Newbridge Financial Services Group, Inc.2,000$3.18K0.00%00.0%Unchanged
Nvest Wealth Strategies, Inc.2,525$4.01K0.00%+2,525New
Federated Hermes, Inc.2,722$4.33K0.00%−344−11.2%Reduced
Hilton Head Capital Partners, LLC3,000$4.77K0.00%+3,000New
Atlantic Union Bankshares Corp3,200$5.09K0.00%00.0%Unchanged
Larson Financial Group LLC4,066$6.46K0.00%+4,066New
The PNC Financial Services Group, Inc.4,422$7.03K0.00%−6−0.1%Reduced
Mirae Asset Global Investments Co., Ltd.4,542$7.22K0.00%+4,542New
JPMorgan Chase & Co6,601$10.5K0.00%+6,601New
Canada Pension Plan Investment Board7,400$11.8K0.00%+7,400New
Allworth Financial LP9,430$15.0K0.00%+9,430New
Chevy Chase Trust Holdings, Inc.10,000$15.9K0.00%00.0%Unchanged
GWM Advisors LLC10,400$16.5K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.10,693$17.0K0.00%+1,359+14.6%Added
J.W. Cole Advisors, Inc.11,269$17.9K0.00%00.0%Unchanged
HBK Sorce Advisory LLC12,344$19.4K0.00%00.0%Unchanged
Buckingham Strategic Partners12,216$19.4K0.00%−35−0.3%Reduced
Capital Advisory Group Advisory Services, LLC12,314$19.6K0.01%00.0%Unchanged
Pinnacle Associates Ltd12,903$20.5K0.00%00.0%Unchanged
Pinnacle Wealth Management Advisory Group, LLC12,903$20.5K0.00%00.0%Unchanged
Bank of New York Mellon Corp12,956$20.6K0.00%−1,095−7.8%Reduced
Modern Wealth Management, LLC15,000$23.9K0.00%+5,000+50.0%Added
Royal Bank of Canada14,874$24.0K0.00%−559,393−97.4%Reduced
China Universal Asset Management Co., Ltd.15,231$24.2K0.00%+15,231New
LPL Financial LLC15,524$24.7K0.00%+5,228+50.8%Added
Bronte Capital Management Pty Ltd.15,627$24.8K0.00%+15,627New
Cetera Investment Advisers15,781$25.1K0.00%+898+6.0%Added
HighTower Advisors, LLC16,934$26.9K0.00%00.0%Unchanged
Creative Planning18,500$29.4K0.00%−422−2.2%Reduced
Liberty Wealth Management LLC19,500$31.0K0.00%00.0%Unchanged
Next Capital Management LLC20,000$31.8K0.01%00.0%Unchanged
Tower Research Capital LLC (TRC)20,351$32.4K0.00%+1,132+5.9%Added
Barclays PLC21,688$34.5K0.00%−84−0.4%Reduced
Russell Investments Group, Ltd.24,347$38.7K0.00%+10,824+80.0%Added
AQR Capital Management LLC25,561$40.6K0.00%−35,846−58.4%Reduced
Credit Agricole S A29,000$46.1K0.00%00.0%Unchanged
Thrive Wealth Management, LLC32,000$50.9K0.01%00.0%Unchanged
Envestnet Asset Management Inc32,307$51.4K0.00%−6,461−16.7%Reduced
Prime Capital Investment Advisors, LLC33,934$54.0K0.00%−740−2.1%Reduced
US Bancorp34,265$54.5K0.00%00.0%Unchanged
HSBC Holdings PLC34,460$55.0K0.00%00.0%Unchanged
Invesco Ltd.35,063$55.8K0.00%+22,856+187.2%Added
Wiley Bros.-Aintree Capital, LLC35,505$56.5K0.00%−8,634−19.6%Reduced
Man Group plc36,712$58.4K0.00%+36,712New
RBF Capital, LLC40,000$63.6K0.00%−40,000−50.0%Reduced
JustInvest LLC42,113$67.0K0.00%−73−0.2%Reduced
Public Employees Retirement System of Ohio42,229$67.1K0.00%00.0%Unchanged
Lighthouse Investment Partners, LLC44,160$70.2K0.00%+44,160New
Jefferies Financial Group Inc.44,840$71.3K0.00%−2,360−5.0%Reduced
Commonwealth Equity Services, LLC45,908$73.0K0.00%−1,025−2.2%Reduced
Squarepoint Ops LLC55,938$88.9K0.00%+31,828+132.0%Added
Nelson Capital Management, LLC58,685$93.3K0.01%−26,335−31.0%Reduced
Acadian Asset Management LLC59,722$94.0K0.00%+59,722New
Citigroup Inc74,571$118.6K0.00%+73,000+4,646.7%Added
ExodusPoint Capital Management, LP77,704$123.5K0.00%+77,704New
Keystone Financial Group80,475$128.0K0.01%+80,475New
Ameriprise Financial Inc85,104$135.3K0.00%−250−0.3%Reduced
Mirae Asset Global ETFs Holdings Ltd.85,246$135.5K0.00%+85,246New
Siren, L.L.C.105,347$167.5K0.00%00.0%Unchanged
Graham Capital Management, L.P.107,253$170.5K0.01%−21,099−16.4%Reduced
American Century Companies Inc112,453$178.8K0.00%+30,651+37.5%Added
Nano Cap New Millennium Growth Fund L P112,500$178.9K0.15%+112,500New
Wells Fargo & Company141,943$225.7K0.00%+116,089+449.0%Added
Bridgeway Capital Management, LLC148,500$236.1K0.00%00.0%Unchanged
Quadrature Capital Ltd159,317$253.3K0.00%+159,317New
Omers Administration Corp178,100$283.2K0.00%+178,100New
Qube Research & Technologies Ltd204,652$325.4K0.00%+159,502+353.3%Added
Northern Trust Corp217,735$346.2K0.00%+12,663+6.2%Added
Milestone Asset Management, LLC231,799$368.6K0.07%+55,832+31.7%Added
Bruce & Co., Inc.250,000$397.5K0.12%00.0%Unchanged
Jane Street Group, LLC295,685$470.1K0.00%−183,753−38.3%Reduced
Morgan Stanley298,456$474.5K0.00%−59,763−16.7%Reduced
Gsa Capital Partners LLP371,372$590.0K0.05%+371,372New
Green Alpha Advisors, LLC375,139$596.5K0.55%+11,440+3.1%Added
Point72 Asset Management, L.P.403,938$642.3K0.00%+115,391+40.0%Added
XTX Topco Ltd413,380$657.3K0.02%−28,161−6.4%Reduced
State Street Corp423,263$673.0K0.00%+37,000+9.6%Added
72 Investment Holdings, LLC474,067$753.8K1.49%00.0%Unchanged