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Caribou Biosciences, Inc.

CRBU
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001619856

No open-market purchases or sales by Caribou Biosciences, Inc. insiders were filed in the last 90 days; 137 institutions reported holding it in 13F filings for Q2 2026, worth $84.8M in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Caribou Biosciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
124
+11 vs. Q3 2025
Shares held
37.1M
+110.9K (+0.3%) vs. Q3 2025
Total value
$58.8M
−$27.8M (−32.1%) vs. Q3 2025
New holders
25
28 more added
Sold out
14
36 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CRBU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 124 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 88 institutionsQ4 2021: 93 institutionsQ1 2022: 104 institutionsQ2 2022: 120 institutionsQ3 2022: 113 institutionsQ4 2022: 133 institutionsQ1 2023: 126 institutionsQ2 2023: 121 institutionsQ3 2023: 126 institutionsQ4 2023: 144 institutionsQ1 2024: 151 institutionsQ2 2024: 140 institutionsQ3 2024: 129 institutionsQ4 2024: 133 institutionsQ1 2025: 131 institutionsQ2 2025: 129 institutionsQ3 2025: 117 institutionsQ4 2025: 124 institutionsQ1 2026: 137 institutionsQ2 2026: 137 institutions
Value heldQ4 2025: $58.8M
Q1 2021: $0Q2 2021: $0Q3 2021: $704.7MQ4 2021: $464.7MQ1 2022: $313.2MQ2 2022: $203.0MQ3 2022: $456.8MQ4 2022: $273.8MQ1 2023: $238.3MQ2 2023: $185.5MQ3 2023: $338.5MQ4 2023: $395.8MQ1 2024: $343.0MQ2 2024: $87.6MQ3 2024: $103.1MQ4 2024: $93.1MQ1 2025: $45.8MQ2 2025: $51.2MQ3 2025: $87.0MQ4 2025: $58.8MQ1 2026: $71.3MQ2 2026: $84.8M
Institutions holding CRBU and their total value by quarter
QuarterHoldersValue
Q2 2026137$84.8M
Q1 2026137$71.3M
Q4 2025124$58.8M
Q3 2025117$87.0M
Q2 2025129$51.2M
Q1 2025131$45.8M
Q4 2024133$93.1M
Q3 2024129$103.1M
Q2 2024140$87.6M
Q1 2024151$343.0M
Q4 2023144$395.8M
Q3 2023126$338.5M
Q2 2023121$185.5M
Q1 2023126$238.3M
Q4 2022133$273.8M
Q3 2022113$456.8M
Q2 2022120$203.0M
Q1 2022104$313.2M
Q4 202193$464.7M
Q3 202188$704.7M
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Caribou Biosciences, Inc.; share changes are against Q3 2025.

Institutions holding CRBU in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Newbridge Financial Services Group, Inc.2,000$3.18K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA1,878$2.99K0.00%+2+0.1%Added
GF Fund Management Co. Ltd.1,835$2.92K0.00%+1,835New
Optiver Holding B.V.1,104$1.75K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC1,026$1.63K0.00%00.0%Unchanged
Harbour Investments, Inc.1,000$1.59K0.00%00.0%Unchanged
Global Retirement Partners, LLC1,000$1.59K0.00%+1,000New
TD Waterhouse Canada Inc.1,000$1.58K0.00%00.0%Unchanged
Basecamp Wealth Advisors LLC937$1.49K0.00%+937New
Tradewinds Capital Management, LLC800$1.27K0.00%00.0%Unchanged
Country Trust Bank700$1.11K0.00%00.0%Unchanged
Fortitude Family Office, LLC646$1.03K0.00%00.0%Unchanged
CWM, LLC575$1.00K0.00%−1,860−76.4%Reduced
Jones Financial Companies LLLP200$3180.00%00.0%Unchanged
Signature Equity Partners, LLC177$2810.00%+177New
Gen-Wealth Partners Inc136$2160.00%00.0%Unchanged
Farther Finance Advisors, LLC100$1590.00%00.0%Unchanged
SBI Securities Co., Ltd.92$1460.00%−66−41.8%Reduced
SRS Capital Advisors, Inc.61$970.00%−445−87.9%Reduced
Paladin Partners, LLC50$800.00%+50New
Sunbelt Securities, Inc.18$290.00%−117−86.7%Reduced
McGuire Capital Advisors Inc10$160.00%+10New
IFP Advisors, Inc1$20.00%−26−96.3%Reduced
DekaBank Deutsche Girozentrale130,000––00.0%Unchanged
Pale Fire Capital SE0$00.00%−775,055−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−558,576−100.0%Sold out
Catalyst Funds Management Pty Ltd0$00.00%−88,300−100.0%Sold out
Thrivent Financial for Lutherans0$00.00%−35,562−100.0%Sold out
Susquehanna Portfolio Strategies, LLC0$00.00%−29,883−100.0%Sold out
Simplex Trading, LLC0$00.00%−21,123−100.0%Sold out
R Squared Ltd0$00.00%−12,268−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−7,500−100.0%Sold out
Group One Trading, L.P.0$00.00%−6,084−100.0%Sold out
Advisory Services Network, LLC0$00.00%−914−100.0%Sold out
Rise Advisors, LLC0$00.00%−548−100.0%Sold out
Principal Securities, Inc.0$00.00%−270−100.0%Sold out
Essential Partners LLC0$00.00%−157−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−24−100.0%Sold out
Cubist Systematic Strategies, LLC––––Not filed
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
FSA Wealth Management LLC––––Not filed
Point72 (DIFC) Ltd––––Not filed