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Caris Life Sciences, Inc.

CAI
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0002019410

In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.

13F holders, Q3 2025

Institutional positions in Caris Life Sciences, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
138
+23 vs. Q2 2025
Shares held
113.4M
+4.45M (+4.1%) vs. Q2 2025
Total value
$3.41B
+$495.5M (+17.0%) vs. Q2 2025
New holders
53
45 more added
Sold out
30
19 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 138 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 116 institutionsQ3 2025: 138 institutionsQ4 2025: 186 institutionsQ1 2026: 202 institutionsQ2 2026: 247 institutions
Value heldQ3 2025: $3.41B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $2.92BQ3 2025: $3.41BQ4 2025: $3.92BQ1 2026: $2.80BQ2 2026: $2.75B
Institutions holding CAI and their total value by quarter
QuarterHoldersValue
Q2 2026247$2.75B
Q1 2026202$2.80B
Q4 2025186$3.92B
Q3 2025138$3.41B
Q2 2025116$2.92B
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q2 2025.

Institutions holding CAI in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Tudor Investment Corp Et Al264,551$8.00M0.05%00.0%Unchanged
Lazard Asset Management LLC277,537$8.40M0.01%+107,608+63.3%Added
Goldman Sachs Group Inc282,209$8.54M0.00%+99,956+54.8%Added
Walleye Capital LLC320,669$9.70M0.08%+282,741+745.5%Added
First Light Asset Management, LLC403,924$11.9M1.12%−39,119−8.8%Reduced
Geode Capital Management, LLC398,328$12.0M0.00%+163,094+69.3%Added
Bank of America Corp429,478$13.0M0.00%+394,289+1,120.5%Added
BlackRock, Inc.647,081$19.6M0.00%+337,979+109.3%Added
Point72 (DIFC) Ltd654,792$19.8M1.38%+600,650+1,109.4%Added
Janus Henderson Group PLC664,438$20.1M0.01%−225,208−25.3%Reduced
Woodline Partners LP723,163$21.9M0.10%−523,163−42.0%Reduced
Rock Springs Capital Management LP793,651$24.0M1.40%00.0%Unchanged
Invesco Ltd.803,802$24.3M0.00%+297,065+58.6%Added
Lord, Abbett & Co. LLC850,000$25.7M0.08%+850,000New
JPMorgan Chase & Co858,105$26.0M0.00%−76,528−8.2%Reduced
Massachusetts Financial Services Co971,330$29.4M0.01%−78,398−7.5%Reduced
Ghisallo Capital Management LLC1,048,163$31.7M1.04%00.0%Unchanged
Perceptive Advisors LLC1,098,163$33.2M0.96%00.0%Unchanged
Alyeska Investment Group, L.P.1,101,071$33.3M0.10%+725,071+192.8%Added
UBS Asset Management Americas Inc1,116,191$33.8M0.01%+316,078+39.5%Added
Alliancebernstein L.P.1,201,985$36.4M0.01%+264,434+28.2%Added
Longaeva Partners L.P.1,285,968$38.9M8.27%−173,777−11.9%Reduced
Canada Pension Plan Investment Board1,322,752$40.0M0.03%00.0%Unchanged
Clearbridge Investments, LLC1,381,230$41.8M0.03%+124,105+9.9%Added
Morgan Stanley1,534,423$46.4M0.00%+729,183+90.6%Added
Ameriprise Financial Inc1,679,468$50.8M0.01%+53,754+3.3%Added
OrbiMed Advisors LLC3,034,858$91.8M2.20%00.0%Unchanged
Neuberger Berman Group LLC4,345,042$109.1M0.08%−1,894,478−30.4%Reduced
PointState Capital LP3,883,721$117.5M2.11%+1,385,364+55.5%Added
Millennium Management LLC3,938,072$119.1M0.09%+424,896+12.1%Added
Silver Lake Group, L.L.C.5,291,006$160.1M3.12%00.0%Unchanged
Price T Rowe Associates Inc6,924,745$209.5M0.02%+163,941+2.4%Added
Braidwell LP7,316,142$221.3M6.57%00.0%Unchanged
T. Rowe Price Investment Management, Inc.8,025,759$242.8M0.15%+721,772+9.9%Added
FMR LLC9,633,435$291.4M0.02%+1,001,890+11.6%Added
Coatue Management LLCSuperinvestorCoatue Management10,142,198$306.8M0.75%00.0%Unchanged
Sixth Street Partners Management Company, L.P.24,385,399$737.7M63.36%00.0%Unchanged
Rakuten Investment Management, Inc.14,518––+14,518New
Capital World Investors0$00.00%−999,945−100.0%Sold out
Citadel Advisors LLC0$00.00%−341,570−100.0%Sold out
Summit Partners Public Asset Management, LLC0$00.00%−296,000−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−150,000−100.0%Sold out
Standard Life Aberdeen plc0$00.00%−117,841−100.0%Sold out
HRT Financial LP0$00.00%−109,318−100.0%Sold out
Blackstone Group Inc.0$00.00%−100,000−100.0%Sold out
Healthcare of Ontario Pension Plan Trust Fund0$00.00%−100,000−100.0%Sold out
Jain Global LLC0$00.00%−87,288−100.0%Sold out
Limestone Investment Advisors LP0$00.00%−86,000−100.0%Sold out
Harbert Fund Advisors, Inc.0$00.00%−80,000−100.0%Sold out
Squarepoint Ops LLC0$00.00%−77,830−100.0%Sold out
Davidson Kempner Capital Management LP0$00.00%−54,000−100.0%Sold out
Winton Group Ltd0$00.00%−44,981−100.0%Sold out
Principal Financial Group Inc0$00.00%−42,026−100.0%Sold out
Pictet Asset Management Holding SA0$00.00%−34,815−100.0%Sold out
Scientech Research LLC0$00.00%−30,727−100.0%Sold out
Westfield Capital Management Co LP0$00.00%−30,000−100.0%Sold out
Greenland Capital Management LP0$00.00%−26,504−100.0%Sold out
Oxford Asset Management LLP0$00.00%−25,000−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−16,880−100.0%Sold out
Aristeia Capital LLC0$00.00%−16,383−100.0%Sold out
Diametric Capital, LP0$00.00%−14,828−100.0%Sold out
Federated Hermes, Inc.0$00.00%−14,200−100.0%Sold out
HBK Investments L P0$00.00%−11,000−100.0%Sold out
Quarry LP0$00.00%−10,623−100.0%Sold out
Bank of Montreal0$00.00%−10,000−100.0%Sold out
Weiss Asset Management LP0$00.00%−10,000−100.0%Sold out
Sectoral Asset Management Inc0$00.00%−8,350−100.0%Sold out
Olistico Wealth, LLC0$00.00%−1,032−100.0%Sold out
Norges Bank––––Not filed