Axsome Therapeutics, Inc.
AXSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001579428
In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Axsome Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 399
- +53 vs. Q3 2025
- Shares held
- 37.6M
- +542.0K (+1.5%) vs. Q3 2025
- Total value
- $6.86B
- +$2.36B (+52.3%) vs. Q3 2025
- New holders
- 87
- 139 more added
- Sold out
- 34
- 122 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 505 | $9.34B |
| Q1 2026 | 410 | $6.41B |
| Q4 2025 | 399 | $6.86B |
| Q3 2025 | 355 | $4.51B |
| Q2 2025 | 348 | $3.95B |
| Q1 2025 | 353 | $4.37B |
| Q4 2024 | 292 | $3.15B |
| Q3 2024 | 280 | $3.48B |
| Q2 2024 | 257 | $3.28B |
| Q1 2024 | 259 | $3.09B |
| Q4 2023 | 245 | $3.07B |
| Q3 2023 | 227 | $2.65B |
| Q2 2023 | 231 | $2.61B |
| Q1 2023 | 197 | $1.97B |
| Q4 2022 | 219 | $2.32B |
| Q3 2022 | 188 | $1.15B |
| Q2 2022 | 174 | $826.7M |
| Q1 2022 | 175 | $787.4M |
| Q4 2021 | 167 | $704.2M |
| Q3 2021 | 171 | $627.3M |
| Q2 2021 | 176 | $1.51B |
| Q1 2021 | 184 | $1.31B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| J. Safra Sarasin Holding AG | 7,383 | $1.35M | 0.02% | −1,514−17.0% | Reduced |
| Oppenheimer & Co Inc | 7,076 | $1.29M | 0.02% | +7,076 | New |
| Glenmede Trust Co NA | 6,924 | $1.26M | 0.01% | +6,924 | New |
| Great Lakes Advisors, LLC | 6,765 | $1.24M | 0.01% | +89+1.3% | Added |
| Pitcairn Wealth Advisors LLC | 6,639 | $1.21M | 0.11% | +6,639 | New |
| Quantinno Capital Management LP | 6,478 | $1.18M | 0.00% | +3,636+127.9% | Added |
| D.A. Davidson & Co. | 6,180 | $1.13M | 0.01% | 00.0% | Unchanged |
| AlphaCentric Advisors LLC | 6,088 | $1.11M | 1.11% | +6,088 | New |
| Birchview Capital, LP | 6,061 | $1.11M | 0.65% | +61+1.0% | Added |
| Stifel Financial Corp | 5,868 | $1.07M | 0.00% | +361+6.6% | Added |
| Baader Bank INC | 5,823 | $1.06M | 0.09% | +3,708+175.3% | Added |
| Cabot Wealth Management Inc | 5,560 | $1.02M | 0.11% | 00.0% | Unchanged |
| Prudential Financial Inc | 5,415 | $989.0K | 0.00% | +357+7.1% | Added |
| Cerity Partners LLC | 5,389 | $984.2K | 0.00% | −15−0.3% | Reduced |
| Headlands Technologies LLC | 5,187 | $947.4K | 0.08% | +2,613+101.5% | Added |
| Teacher Retirement System of Texas | 5,164 | $943.2K | 0.00% | −3,293−38.9% | Reduced |
| CWM, LLC | 5,149 | $940.0K | 0.00% | −20.0% | Reduced |
| Yarbrough Capital, LLC | 5,054 | $923.1K | 0.03% | 00.0% | Unchanged |
| Odyssean, LLC | 4,983 | $910.1K | 0.65% | +4,983 | New |
| Victory Capital Management Inc | 4,776 | $872.3K | 0.00% | +36+0.8% | Added |
| Lighthouse Investment Partners, LLC | 4,640 | $847.5K | 0.03% | +4,640 | New |
| Virtus Investment Advisers, Inc. | 4,611 | $842.2K | 0.23% | +428+10.2% | Added |
| Toroso Investments, LLC | 4,519 | $825.4K | 0.00% | +498+12.4% | Added |
| Values First Advisors, Inc. | 4,402 | $803.9K | 0.42% | −480−9.8% | Reduced |
| Tocqueville Asset Management L.P. | 4,400 | $803.6K | 0.01% | −1,250−22.1% | Reduced |
| Goodwin Investment Advisory | 4,241 | $774.6K | 0.85% | 00.0% | Unchanged |
| FORA Capital, LLC | 5,714 | $740.2K | 0.09% | +5,714 | New |
| Intrust Bank NA | 4,052 | $740.1K | 0.06% | +288+7.7% | Added |
| Los Angeles Capital Management LLC | 5,555 | $739.6K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 4,007 | $732.0K | 0.00% | −4,984−55.4% | Reduced |
| Farallon Capital Management, L.L.C. | 4,000 | $730.6K | 0.00% | 00.0% | Unchanged |
| Mirador Capital Partners LP | 4,000 | $730.6K | 0.10% | 00.0% | Unchanged |
| Aries Wealth Management | 4,000 | $730.6K | 0.16% | 00.0% | Unchanged |
| Csenge Advisory Group | 3,996 | $729.8K | 0.03% | +3,996 | New |
| Inceptionr LLC | 3,934 | $718.5K | 0.20% | −4,725−54.6% | Reduced |
| Forbes J M & Co LLP | 3,704 | $676.5K | 0.05% | 00.0% | Unchanged |
| Public Employees Retirement Association of Colorado | 3,704 | $676.0K | 0.00% | 00.0% | Unchanged |
| Scientech Research LLC | 3,593 | $656.2K | 0.41% | +3,593 | New |
| PDT Partners, LLC | 3,577 | $653.3K | 0.04% | +3,577 | New |
| Cynosure Management, LLC | 3,475 | $634.7K | 0.06% | −4,369−55.7% | Reduced |
| Verition Fund Management LLC | 3,409 | $622.6K | 0.00% | +1,420+71.4% | Added |
| Ameritas Investment Partners, Inc. | 3,381 | $617.5K | 0.02% | 00.0% | Unchanged |
| Pathstone Holdings, LLC | 3,277 | $598.5K | 0.00% | −522−13.7% | Reduced |
| Xponance, Inc. | 3,265 | $596.3K | 0.00% | +76+2.4% | Added |
| Mercer Global Advisors Inc | 3,222 | $588.5K | 0.00% | +1,260+64.2% | Added |
| Leonteq Securities AG | 3,219 | $587.9K | 0.03% | −518−13.9% | Reduced |
| Truist Financial Corp | 3,055 | $558.0K | 0.00% | +1,100+56.3% | Added |
| Old North State Wealth Management, LLC | 2,800 | $511.4K | 0.24% | −650−18.8% | Reduced |
| Mackenzie Financial Corp | 3,382 | $502.2K | 0.00% | 00.0% | Unchanged |
| Cambridge Investment Research Advisors, Inc. | 2,729 | $498.0K | 0.00% | +2,729 | New |
| CIBC World Markets Corp | 2,715 | $495.9K | 0.00% | +2,715 | New |
| M&T Bank Corp | 2,560 | $467.5K | 0.00% | +696+37.3% | Added |
| Quantitative Investment Management, LLC | 2,524 | $460.0K | 0.04% | +429+20.5% | Added |
| Fifth Third Bancorp | 2,477 | $452.4K | 0.00% | +2,265+1,068.4% | Added |
| Profund Advisors LLC | 2,468 | $450.8K | 0.01% | −654−20.9% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,450 | $447.5K | 0.00% | +521+27.0% | Added |
| NBC Securities, Inc. | 2,435 | $444.7K | 0.03% | −235−8.8% | Reduced |
| Moors & Cabot, Inc. | 2,430 | $443.8K | 0.02% | +50+2.1% | Added |
| MML Investors Services, LLC | 2,388 | $436.1K | 0.00% | +2,388 | New |
| O'Shaughnessy Asset Management, LLC | 2,370 | $432.9K | 0.00% | +40+1.7% | Added |
| Fiduciary Family Office, LLC | 2,283 | $417.0K | 0.12% | −387−14.5% | Reduced |
| McAdam, LLC | 2,274 | $415.3K | 0.02% | +76+3.5% | Added |
| Howland Capital Management LLC | 2,220 | $405.5K | 0.02% | +2,220 | New |
| JustInvest LLC | 2,190 | $400.0K | 0.00% | +89+4.2% | Added |
| Invst, LLC | 2,140 | $390.9K | 0.04% | 00.0% | Unchanged |
| Adams Wealth Management | 2,169 | $389.1K | 0.08% | 00.0% | Unchanged |
| CacheTech Inc. | 2,169 | $389.1K | 0.07% | 00.0% | Unchanged |
| Prelude Capital Management, LLC | 2,129 | $388.8K | 0.03% | +2,129 | New |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 2,110 | $385.4K | 0.06% | +2,110 | New |
| The PNC Financial Services Group, Inc. | 1,921 | $350.9K | 0.00% | +65+3.5% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 1,900 | $347.0K | 0.00% | +1,900 | New |
| Tortoise Investment Management, LLC | 1,870 | $341.5K | 0.03% | −266−12.5% | Reduced |
| Signature Estate & Investment Advisors LLC | 1,832 | $334.6K | 0.01% | 00.0% | Unchanged |
| Impact Partnership Wealth, LLC | 1,822 | $332.8K | 0.04% | +1,822 | New |
| Davenport & Co LLC | 1,800 | $328.8K | 0.00% | −67−3.6% | Reduced |
| Legacy Capital Wealth Management, LLC | 1,785 | $326.0K | 0.20% | +1,785 | New |
| Tower Research Capital LLC (TRC) | 1,772 | $323.6K | 0.01% | +1,010+132.5% | Added |
| Sectoral Asset Management Inc | 1,740 | $317.8K | 0.25% | +720+70.6% | Added |
| Yorktown Management & Research Co Inc | 1,700 | $310.5K | 0.25% | +1,700 | New |
| CIBC Asset Management Inc | 1,699 | $310.3K | 0.00% | +1,699 | New |
| WealthPlan Investment Management, LLC | 1,693 | $309.2K | 0.02% | 00.0% | Unchanged |
| Brinker Capital Investments, LLC | 1,683 | $307.4K | 0.00% | −506−23.1% | Reduced |
| Vident Advisory, LLC | 1,677 | $306.3K | 0.00% | −280−14.3% | Reduced |
| Atria Investments LLC | 1,663 | $303.7K | 0.00% | −106−6.0% | Reduced |
| Concurrent Investment Advisors, LLC | 1,643 | $300.1K | 0.00% | +1,643 | New |
| Snowden Capital Advisors LLC | 1,638 | $299.2K | 0.01% | +1,638 | New |
| Wiley Bros.-Aintree Capital, LLC | 1,602 | $292.6K | 0.00% | +1,602 | New |
| Swiss Life Asset Management Ltd | 1,576 | $287.8K | 0.00% | +1,576 | New |
| Rafferty Asset Management, LLC | 1,567 | $286.2K | 0.00% | −175−10.0% | Reduced |
| AlphaGrep UK Ltd | 1,563 | $285.5K | 0.10% | +1,563 | New |
| Graham Capital Management, L.P. | 1,532 | $279.8K | 0.01% | −1,075−41.2% | Reduced |
| Diametric Capital, LP | 1,525 | $278.5K | 0.07% | +1,525 | New |
| Commonwealth Equity Services, LLC | 1,522 | $278.0K | 0.00% | +1,522 | New |
| Grimes & Company, Inc. | 1,460 | $266.7K | 0.01% | +1,460 | New |
| Allworth Financial LP | 1,459 | $266.5K | 0.00% | +17+1.2% | Added |
| Bessemer Group Inc | 1,436 | $262.0K | 0.00% | +21+1.5% | Added |
| Petix & Botte Co | 1,430 | $261.2K | 0.06% | +1,430 | New |
| Quest Partners LLC | 1,408 | $257.2K | 0.01% | +854+154.2% | Added |
| Empowered Funds, LLC | 1,302 | $237.8K | 0.00% | +1,302 | New |
| Allianz Asset Management GmbH | 1,300 | $237.4K | 0.00% | +1,300 | New |