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Axsome Therapeutics, Inc.

AXSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001579428

In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Axsome Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
399
+53 vs. Q3 2025
Shares held
37.6M
+542.0K (+1.5%) vs. Q3 2025
Total value
$6.86B
+$2.36B (+52.3%) vs. Q3 2025
New holders
87
139 more added
Sold out
34
122 more reduced

9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 399 institutions
Q1 2021: 184 institutionsQ2 2021: 176 institutionsQ3 2021: 171 institutionsQ4 2021: 167 institutionsQ1 2022: 175 institutionsQ2 2022: 174 institutionsQ3 2022: 188 institutionsQ4 2022: 219 institutionsQ1 2023: 197 institutionsQ2 2023: 231 institutionsQ3 2023: 227 institutionsQ4 2023: 245 institutionsQ1 2024: 259 institutionsQ2 2024: 257 institutionsQ3 2024: 280 institutionsQ4 2024: 292 institutionsQ1 2025: 353 institutionsQ2 2025: 348 institutionsQ3 2025: 355 institutionsQ4 2025: 399 institutionsQ1 2026: 410 institutionsQ2 2026: 505 institutions
Value heldQ4 2025: $6.86B
Q1 2021: $1.31BQ2 2021: $1.51BQ3 2021: $627.3MQ4 2021: $704.2MQ1 2022: $787.4MQ2 2022: $826.7MQ3 2022: $1.15BQ4 2022: $2.32BQ1 2023: $1.97BQ2 2023: $2.61BQ3 2023: $2.65BQ4 2023: $3.07BQ1 2024: $3.09BQ2 2024: $3.28BQ3 2024: $3.48BQ4 2024: $3.15BQ1 2025: $4.37BQ2 2025: $3.95BQ3 2025: $4.51BQ4 2025: $6.86BQ1 2026: $6.41BQ2 2026: $9.34B
Institutions holding AXSM and their total value by quarter
QuarterHoldersValue
Q2 2026505$9.34B
Q1 2026410$6.41B
Q4 2025399$6.86B
Q3 2025355$4.51B
Q2 2025348$3.95B
Q1 2025353$4.37B
Q4 2024292$3.15B
Q3 2024280$3.48B
Q2 2024257$3.28B
Q1 2024259$3.09B
Q4 2023245$3.07B
Q3 2023227$2.65B
Q2 2023231$2.61B
Q1 2023197$1.97B
Q4 2022219$2.32B
Q3 2022188$1.15B
Q2 2022174$826.7M
Q1 2022175$787.4M
Q4 2021167$704.2M
Q3 2021171$627.3M
Q2 2021176$1.51B
Q1 2021184$1.31B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding AXSM in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Fairmount Funds Management LLC0$00.00%−815,176−100.0%Sold out
HSBC Holdings PLC0$00.00%−101,001−100.0%Sold out
SVB Capital Management, LLC0$00.00%−33,849−100.0%Sold out
Capital Fund Management S.A.0$00.00%−28,758−100.0%Sold out
Jump Financial, LLC0$00.00%−25,000−100.0%Sold out
Alps Advisors Inc0$00.00%−24,437−100.0%Sold out
Readystate Asset Management LP0$00.00%−17,860−100.0%Sold out
SummitTX Capital, L.P.0$00.00%−15,350−100.0%Sold out
Jain Global LLC0$00.00%−9,007−100.0%Sold out
J. Goldman & Co LP0$00.00%−8,401−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−7,426−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−7,267−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−6,552−100.0%Sold out
Pitcairn Co0$00.00%−6,106−100.0%Sold out
Henshaw Capital LLC0$00.00%−5,036−100.0%Sold out
Cornerstone Select Advisors, LLC0$00.00%−4,375−100.0%Sold out
Freestone Grove Partners LP0$00.00%−2,494−100.0%Sold out
National Asset Management, Inc.0$00.00%−2,473−100.0%Sold out
Lombard Odier Asset Management (USA) Corp0$00.00%−2,379−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−2,263−100.0%Sold out
Bank Hapoalim BM0$00.00%−1,750−100.0%Sold out
Ameritas Advisory Services, LLC0$00.00%−735−100.0%Sold out
Johnson Financial Group, Inc.0$00.00%−503−100.0%Sold out
Natixis0$00.00%−485−100.0%Sold out
Advisory Services Network, LLC0$00.00%−330−100.0%Sold out
Rise Advisors, LLC0$00.00%−80−100.0%Sold out
JPL Wealth Management, LLC0$00.00%−76−100.0%Sold out
Principal Securities, Inc.0$00.00%−33−100.0%Sold out
GPS Wealth Strategies Group, LLC0$00.00%−18−100.0%Sold out
Geneos Wealth Management Inc.0$00.00%−16−100.0%Sold out
Montag A & Associates Inc0$00.00%−8−100.0%Sold out
GHP Investment Advisors, Inc.0$00.00%−6−100.0%Sold out
Atlantic Union Bankshares Corp0$00.00%−1−100.0%Sold out
Synovus Financial Corp––––Not filed
Cubist Systematic Strategies, LLC––––Not filed
Wolverine Trading, LLC––––Not filed
Glenmede Investment Management, LP––––Not filed
Lion Street Advisors, LLC––––Not filed
CIBC Bancorp USA Inc.––––Not filed
Point72 Hong Kong Ltd––––Not filed
Point72 (DIFC) Ltd––––Not filed
Abich Financial Wealth Management LLC––––Not filed