Axsome Therapeutics, Inc.
AXSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001579428
In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Axsome Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 399
- +53 vs. Q3 2025
- Shares held
- 37.6M
- +542.0K (+1.5%) vs. Q3 2025
- Total value
- $6.86B
- +$2.36B (+52.3%) vs. Q3 2025
- New holders
- 87
- 139 more added
- Sold out
- 34
- 122 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 505 | $9.34B |
| Q1 2026 | 410 | $6.41B |
| Q4 2025 | 399 | $6.86B |
| Q3 2025 | 355 | $4.51B |
| Q2 2025 | 348 | $3.95B |
| Q1 2025 | 353 | $4.37B |
| Q4 2024 | 292 | $3.15B |
| Q3 2024 | 280 | $3.48B |
| Q2 2024 | 257 | $3.28B |
| Q1 2024 | 259 | $3.09B |
| Q4 2023 | 245 | $3.07B |
| Q3 2023 | 227 | $2.65B |
| Q2 2023 | 231 | $2.61B |
| Q1 2023 | 197 | $1.97B |
| Q4 2022 | 219 | $2.32B |
| Q3 2022 | 188 | $1.15B |
| Q2 2022 | 174 | $826.7M |
| Q1 2022 | 175 | $787.4M |
| Q4 2021 | 167 | $704.2M |
| Q3 2021 | 171 | $627.3M |
| Q2 2021 | 176 | $1.51B |
| Q1 2021 | 184 | $1.31B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Blair William & Co | 46,840 | $8.55M | 0.02% | −3,237−6.5% | Reduced |
| Bridgewater Associates, LP | 47,444 | $8.67M | 0.03% | +47,444 | New |
| SEI Investments Co | 47,600 | $8.69M | 0.01% | −527−1.1% | Reduced |
| Baldwin Brothers Inc | 48,570 | $8.87M | 0.57% | 00.0% | Unchanged |
| Trexquant Investment LP | 49,136 | $8.97M | 0.08% | +39,615+416.1% | Added |
| Rhumbline Advisers | 52,233 | $9.54M | 0.01% | −8,545−14.1% | Reduced |
| Alliancebernstein L.P. | 53,140 | $9.71M | 0.00% | −9,925−15.7% | Reduced |
| Atika Capital Management LLC | 55,500 | $10.1M | 1.41% | +6,500+13.3% | Added |
| HighTower Advisors, LLC | 55,972 | $10.2M | 0.01% | −1,143−2.0% | Reduced |
| Edgestream Partners, L.P. | 56,364 | $10.3M | 0.29% | +38,018+207.2% | Added |
| Privium Fund Management B.V. | 56,878 | $10.4M | 1.91% | +4,146+7.9% | Added |
| Walleye Capital LLC | 60,100 | $11.0M | 0.06% | +59,600+11,920.0% | Added |
| IFP Advisors, Inc | 62,448 | $11.4M | 0.26% | −865−1.4% | Reduced |
| Axiom Investors LLC | 63,390 | $11.6M | 0.10% | +14,137+28.7% | Added |
| Emerald Mutual Fund Advisers Trust | 67,608 | $12.3M | 0.60% | +2,103+3.2% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 68,858 | $12.6M | 0.02% | +956+1.4% | Added |
| Swiss National Bank | 68,900 | $12.6M | 0.01% | +2,100+3.1% | Added |
| Neuberger Berman Group LLC | 69,483 | $12.7M | 0.01% | −21,695−23.8% | Reduced |
| Summit Financial, LLC | 70,628 | $12.9M | 0.19% | −6,912−8.9% | Reduced |
| Iridian Asset Management LLC | 73,783 | $13.5M | 4.96% | −9,770−11.7% | Reduced |
| Cormorant Asset Management, LP | 75,000 | $13.7M | 0.78% | −25,000−25.0% | Reduced |
| Barclays PLC | 76,853 | $14.0M | 0.01% | +4,786+6.6% | Added |
| Spears Abacus Advisors LLC | 84,154 | $15.4M | 0.29% | +30.0% | Added |
| Granite Investment Partners, LLC | 84,894 | $15.5M | 0.92% | −3,664−4.1% | Reduced |
| UBS Asset Management Americas Inc | 87,249 | $15.9M | 0.00% | +558+0.6% | Added |
| Federated Hermes, Inc. | 87,280 | $15.9M | 0.03% | +29,995+52.4% | Added |
| Wells Fargo & Company | 89,661 | $16.4M | 0.00% | +34,388+62.2% | Added |
| M&G Plc | 90,328 | $16.5M | 0.08% | +90,328 | New |
| WCM Investment Management, LLC | 112,058 | $16.7M | 0.03% | −7,638−6.4% | Reduced |
| Nicholas Investment Partners, LP | 91,564 | $16.7M | 1.22% | +42,907+88.2% | Added |
| Royce & Associates LP | 94,017 | $17.2M | 0.17% | +37,981+67.8% | Added |
| Standard Life Aberdeen plc | 97,413 | $17.8M | 0.03% | +2,765+2.9% | Added |
| Deutsche Bank AG | 98,257 | $17.9M | 0.01% | +1,565+1.6% | Added |
| Ameriprise Financial Inc | 99,916 | $18.2M | 0.00% | −8,320−7.7% | Reduced |
| DnB Asset Management AS | 101,102 | $18.5M | 0.06% | −879−0.9% | Reduced |
| Canada Pension Plan Investment Board | 103,200 | $18.8M | 0.01% | +38,800+60.2% | Added |
| AQR Capital Management LLC | 103,418 | $18.9M | 0.01% | −15,238−12.8% | Reduced |
| Emerald Advisers, LLC | 108,082 | $19.7M | 0.61% | −860−0.8% | Reduced |
| Voleon Capital Management LP | 110,179 | $20.1M | 0.43% | +93,445+558.4% | Added |
| Rhenman & Partners Asset Management AB | 114,800 | $21.0M | 1.96% | −58,000−33.6% | Reduced |
| Manufacturers Life Insurance Company, The | 133,884 | $23.7M | 0.02% | +1,167+0.9% | Added |
| US Bancorp | 130,985 | $23.9M | 0.03% | −548−0.4% | Reduced |
| Raymond James Financial Inc | 150,098 | $24.8M | 0.01% | −8,591−5.4% | Reduced |
| Jane Street Group, LLC | 137,283 | $25.1M | 0.03% | +6,438+4.9% | Added |
| Citadel Advisors LLC | 138,213 | $25.2M | 0.02% | −20,193−12.7% | Reduced |
| Two Sigma Investments, LP | 145,597 | $26.6M | 0.04% | +137,390+1,674.1% | Added |
| Perceptive Advisors LLC | 148,900 | $27.2M | 0.50% | 00.0% | Unchanged |
| Algert Global LLC | 149,392 | $27.3M | 0.43% | +105,242+238.4% | Added |
| Woodline Partners LP | 150,864 | $27.6M | 0.11% | −181,000−54.5% | Reduced |
| Squarepoint Ops LLC | 155,000 | $28.3M | 0.06% | 00.0% | Unchanged |
| Frontier Capital Management Co LLC | 157,691 | $28.8M | 0.31% | +31,309+24.8% | Added |
| MetLife Investment Management | 164,871 | $30.1M | 0.15% | −32,447−16.4% | Reduced |
| Renaissance Technologies LLC | 170,000 | $31.0M | 0.05% | +20,000+13.3% | Added |
| Voya Investment Management LLC | 173,301 | $31.7M | 0.03% | +59,251+52.0% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 188,258 | $34.4M | 0.09% | −20,811−10.0% | Reduced |
| Two Sigma Advisers, LP | 188,500 | $34.4M | 0.07% | +188,500 | New |
| Tri Locum Partners LP | 201,627 | $36.8M | 4.78% | −90,510−31.0% | Reduced |
| Citigroup Inc | 204,104 | $37.3M | 0.03% | +62,091+43.7% | Added |
| First Turn Management, LLC | 206,921 | $37.8M | 4.32% | +54,307+35.6% | Added |
| Vestal Point Capital, LP | 210,000 | $38.4M | 1.41% | +60,000+40.0% | Added |
| Driehaus Capital Management LLC | 220,518 | $40.3M | 0.27% | −2,890−1.3% | Reduced |
| Man Group plc | 228,641 | $41.8M | 0.08% | −59,267−20.6% | Reduced |
| JPMorgan Chase & Co | 233,191 | $42.6M | 0.00% | −17,322−6.9% | Reduced |
| PFM Health Sciences, LP | 251,562 | $45.9M | 4.65% | −278,770−52.6% | Reduced |
| OrbiMed Advisors LLC | 253,121 | $46.2M | 0.95% | −278,679−52.4% | Reduced |
| Bank of New York Mellon Corp | 255,097 | $46.6M | 0.01% | +1,834+0.7% | Added |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 278,835 | $50.9M | 4.52% | −47,483−14.6% | Reduced |
| Goldman Sachs Group Inc | 300,906 | $55.0M | 0.01% | +76,767+34.2% | Added |
| BNP Paribas Arbitrage, SA | 304,388 | $55.6M | 0.04% | +114,282+60.1% | Added |
| Loomis Sayles & Co L P | 315,391 | $57.6M | 0.07% | −14,734−4.5% | Reduced |
| Marshall Wace, LLP | 320,568 | $58.5M | 0.06% | −57,456−15.2% | Reduced |
| Qube Research & Technologies Ltd | 325,440 | $59.4M | 0.09% | −186−0.1% | Reduced |
| Franklin Resources Inc | 342,573 | $62.6M | 0.02% | +56,975+19.9% | Added |
| Nuveen, LLC | 349,209 | $63.8M | 0.02% | +50,868+17.1% | Added |
| UBS Group AG | 355,318 | $64.9M | 0.01% | +142,867+67.2% | Added |
| Principal Financial Group Inc | 363,114 | $66.3M | 0.03% | −5,320−1.4% | Reduced |
| Hood River Capital Management LLC | 366,176 | $66.9M | 0.73% | +6,219+1.7% | Added |
| Adage Capital Partners GP, L.L.C. | 367,578 | $67.1M | 0.10% | −77,422−17.4% | Reduced |
| Northern Trust Corp | 390,431 | $71.3M | 0.01% | −19,104−4.7% | Reduced |
| Charles Schwab Investment Management Inc | 402,700 | $73.5M | 0.01% | +20,653+5.4% | Added |
| Pictet Asset Management Holding SA | 436,063 | $79.6M | 0.08% | +73,925+20.4% | Added |
| Assenagon Asset Management S.A. | 467,982 | $85.5M | 0.13% | +173,211+58.8% | Added |
| Morgan Stanley | 491,201 | $89.7M | 0.01% | +81,621+19.9% | Added |
| Norges Bank | 495,456 | $90.5M | 0.01% | +495,456 | New |
| D. E. Shaw & Co., Inc. | 549,113 | $100.3M | 0.08% | +252,826+85.3% | Added |
| Eventide Asset Management, LLC | 571,226 | $104.2M | 1.63% | −175,172−23.5% | Reduced |
| Bank of America Corp | 618,033 | $112.9M | 0.01% | +256,772+71.1% | Added |
| Alethea Capital Management, LLC | 668,710 | $122.1M | 59.30% | −2,173−0.3% | Reduced |
| RTW Investments, LP | 888,001 | $162.2M | 1.62% | −230,882−20.6% | Reduced |
| State Street Corp | 958,150 | $175.0M | 0.01% | +15,190+1.6% | Added |
| Nomura Asset Management International Inc. | 989,447 | $180.7M | 0.27% | +989,447 | New |
| Geode Capital Management, LLC | 1,010,249 | $184.5M | 0.01% | +12,549+1.3% | Added |
| Deep Track Capital, LP | 1,150,000 | $210.0M | 4.79% | +250,000+27.8% | Added |
| FMR LLC | 1,181,622 | $215.8M | 0.01% | +253,739+27.3% | Added |
| Wellington Management Group LLP | 1,221,656 | $223.1M | 0.04% | −112,904−8.5% | Reduced |
| Invesco Ltd. | 1,273,494 | $232.6M | 0.02% | +282,937+28.6% | Added |
| Price T Rowe Associates Inc | 1,509,870 | $275.8M | 0.03% | +472,422+45.5% | Added |
| BlackRock, Inc. | 3,913,543 | $714.8M | 0.01% | +122,614+3.2% | Added |
| Vanguard Group Inc | 4,164,818 | $760.7M | 0.01% | −15,828−0.4% | Reduced |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −1,084,536−100.0% | Sold out |