Axsome Therapeutics, Inc.
AXSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001579428
In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Axsome Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 399
- +53 vs. Q3 2025
- Shares held
- 37.6M
- +542.0K (+1.5%) vs. Q3 2025
- Total value
- $6.86B
- +$2.36B (+52.3%) vs. Q3 2025
- New holders
- 87
- 139 more added
- Sold out
- 34
- 122 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 505 | $9.34B |
| Q1 2026 | 410 | $6.41B |
| Q4 2025 | 399 | $6.86B |
| Q3 2025 | 355 | $4.51B |
| Q2 2025 | 348 | $3.95B |
| Q1 2025 | 353 | $4.37B |
| Q4 2024 | 292 | $3.15B |
| Q3 2024 | 280 | $3.48B |
| Q2 2024 | 257 | $3.28B |
| Q1 2024 | 259 | $3.09B |
| Q4 2023 | 245 | $3.07B |
| Q3 2023 | 227 | $2.65B |
| Q2 2023 | 231 | $2.61B |
| Q1 2023 | 197 | $1.97B |
| Q4 2022 | 219 | $2.32B |
| Q3 2022 | 188 | $1.15B |
| Q2 2022 | 174 | $826.7M |
| Q1 2022 | 175 | $787.4M |
| Q4 2021 | 167 | $704.2M |
| Q3 2021 | 171 | $627.3M |
| Q2 2021 | 176 | $1.51B |
| Q1 2021 | 184 | $1.31B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Empowered Funds, LLC | 1,302 | $237.8K | 0.00% | +1,302 | New |
| Quest Partners LLC | 1,408 | $257.2K | 0.01% | +854+154.2% | Added |
| Petix & Botte Co | 1,430 | $261.2K | 0.06% | +1,430 | New |
| Bessemer Group Inc | 1,436 | $262.0K | 0.00% | +21+1.5% | Added |
| Allworth Financial LP | 1,459 | $266.5K | 0.00% | +17+1.2% | Added |
| Grimes & Company, Inc. | 1,460 | $266.7K | 0.01% | +1,460 | New |
| Commonwealth Equity Services, LLC | 1,522 | $278.0K | 0.00% | +1,522 | New |
| Diametric Capital, LP | 1,525 | $278.5K | 0.07% | +1,525 | New |
| Graham Capital Management, L.P. | 1,532 | $279.8K | 0.01% | −1,075−41.2% | Reduced |
| AlphaGrep UK Ltd | 1,563 | $285.5K | 0.10% | +1,563 | New |
| Rafferty Asset Management, LLC | 1,567 | $286.2K | 0.00% | −175−10.0% | Reduced |
| Swiss Life Asset Management Ltd | 1,576 | $287.8K | 0.00% | +1,576 | New |
| Wiley Bros.-Aintree Capital, LLC | 1,602 | $292.6K | 0.00% | +1,602 | New |
| Snowden Capital Advisors LLC | 1,638 | $299.2K | 0.01% | +1,638 | New |
| Concurrent Investment Advisors, LLC | 1,643 | $300.1K | 0.00% | +1,643 | New |
| Atria Investments LLC | 1,663 | $303.7K | 0.00% | −106−6.0% | Reduced |
| Vident Advisory, LLC | 1,677 | $306.3K | 0.00% | −280−14.3% | Reduced |
| Brinker Capital Investments, LLC | 1,683 | $307.4K | 0.00% | −506−23.1% | Reduced |
| WealthPlan Investment Management, LLC | 1,693 | $309.2K | 0.02% | 00.0% | Unchanged |
| CIBC Asset Management Inc | 1,699 | $310.3K | 0.00% | +1,699 | New |
| Yorktown Management & Research Co Inc | 1,700 | $310.5K | 0.25% | +1,700 | New |
| Sectoral Asset Management Inc | 1,740 | $317.8K | 0.25% | +720+70.6% | Added |
| Tower Research Capital LLC (TRC) | 1,772 | $323.6K | 0.01% | +1,010+132.5% | Added |
| Legacy Capital Wealth Management, LLC | 1,785 | $326.0K | 0.20% | +1,785 | New |
| Davenport & Co LLC | 1,800 | $328.8K | 0.00% | −67−3.6% | Reduced |
| Impact Partnership Wealth, LLC | 1,822 | $332.8K | 0.04% | +1,822 | New |
| Signature Estate & Investment Advisors LLC | 1,832 | $334.6K | 0.01% | 00.0% | Unchanged |
| Tortoise Investment Management, LLC | 1,870 | $341.5K | 0.03% | −266−12.5% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 1,900 | $347.0K | 0.00% | +1,900 | New |
| The PNC Financial Services Group, Inc. | 1,921 | $350.9K | 0.00% | +65+3.5% | Added |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 2,110 | $385.4K | 0.06% | +2,110 | New |
| Prelude Capital Management, LLC | 2,129 | $388.8K | 0.03% | +2,129 | New |
| Adams Wealth Management | 2,169 | $389.1K | 0.08% | 00.0% | Unchanged |
| CacheTech Inc. | 2,169 | $389.1K | 0.07% | 00.0% | Unchanged |
| Invst, LLC | 2,140 | $390.9K | 0.04% | 00.0% | Unchanged |
| JustInvest LLC | 2,190 | $400.0K | 0.00% | +89+4.2% | Added |
| Howland Capital Management LLC | 2,220 | $405.5K | 0.02% | +2,220 | New |
| McAdam, LLC | 2,274 | $415.3K | 0.02% | +76+3.5% | Added |
| Fiduciary Family Office, LLC | 2,283 | $417.0K | 0.12% | −387−14.5% | Reduced |
| O'Shaughnessy Asset Management, LLC | 2,370 | $432.9K | 0.00% | +40+1.7% | Added |
| MML Investors Services, LLC | 2,388 | $436.1K | 0.00% | +2,388 | New |
| Moors & Cabot, Inc. | 2,430 | $443.8K | 0.02% | +50+2.1% | Added |
| NBC Securities, Inc. | 2,435 | $444.7K | 0.03% | −235−8.8% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,450 | $447.5K | 0.00% | +521+27.0% | Added |
| Profund Advisors LLC | 2,468 | $450.8K | 0.01% | −654−20.9% | Reduced |
| Fifth Third Bancorp | 2,477 | $452.4K | 0.00% | +2,265+1,068.4% | Added |
| Quantitative Investment Management, LLC | 2,524 | $460.0K | 0.04% | +429+20.5% | Added |
| M&T Bank Corp | 2,560 | $467.5K | 0.00% | +696+37.3% | Added |
| CIBC World Markets Corp | 2,715 | $495.9K | 0.00% | +2,715 | New |
| Cambridge Investment Research Advisors, Inc. | 2,729 | $498.0K | 0.00% | +2,729 | New |
| Mackenzie Financial Corp | 3,382 | $502.2K | 0.00% | 00.0% | Unchanged |
| Old North State Wealth Management, LLC | 2,800 | $511.4K | 0.24% | −650−18.8% | Reduced |
| Truist Financial Corp | 3,055 | $558.0K | 0.00% | +1,100+56.3% | Added |
| Leonteq Securities AG | 3,219 | $587.9K | 0.03% | −518−13.9% | Reduced |
| Mercer Global Advisors Inc | 3,222 | $588.5K | 0.00% | +1,260+64.2% | Added |
| Xponance, Inc. | 3,265 | $596.3K | 0.00% | +76+2.4% | Added |
| Pathstone Holdings, LLC | 3,277 | $598.5K | 0.00% | −522−13.7% | Reduced |
| Ameritas Investment Partners, Inc. | 3,381 | $617.5K | 0.02% | 00.0% | Unchanged |
| Verition Fund Management LLC | 3,409 | $622.6K | 0.00% | +1,420+71.4% | Added |
| Cynosure Management, LLC | 3,475 | $634.7K | 0.06% | −4,369−55.7% | Reduced |
| PDT Partners, LLC | 3,577 | $653.3K | 0.04% | +3,577 | New |
| Scientech Research LLC | 3,593 | $656.2K | 0.41% | +3,593 | New |
| Public Employees Retirement Association of Colorado | 3,704 | $676.0K | 0.00% | 00.0% | Unchanged |
| Forbes J M & Co LLP | 3,704 | $676.5K | 0.05% | 00.0% | Unchanged |
| Inceptionr LLC | 3,934 | $718.5K | 0.20% | −4,725−54.6% | Reduced |
| Csenge Advisory Group | 3,996 | $729.8K | 0.03% | +3,996 | New |
| Farallon Capital Management, L.L.C. | 4,000 | $730.6K | 0.00% | 00.0% | Unchanged |
| Mirador Capital Partners LP | 4,000 | $730.6K | 0.10% | 00.0% | Unchanged |
| Aries Wealth Management | 4,000 | $730.6K | 0.16% | 00.0% | Unchanged |
| Great West Life Assurance Co | 4,007 | $732.0K | 0.00% | −4,984−55.4% | Reduced |
| Los Angeles Capital Management LLC | 5,555 | $739.6K | 0.00% | 00.0% | Unchanged |
| Intrust Bank NA | 4,052 | $740.1K | 0.06% | +288+7.7% | Added |
| FORA Capital, LLC | 5,714 | $740.2K | 0.09% | +5,714 | New |
| Goodwin Investment Advisory | 4,241 | $774.6K | 0.85% | 00.0% | Unchanged |
| Tocqueville Asset Management L.P. | 4,400 | $803.6K | 0.01% | −1,250−22.1% | Reduced |
| Values First Advisors, Inc. | 4,402 | $803.9K | 0.42% | −480−9.8% | Reduced |
| Toroso Investments, LLC | 4,519 | $825.4K | 0.00% | +498+12.4% | Added |
| Virtus Investment Advisers, Inc. | 4,611 | $842.2K | 0.23% | +428+10.2% | Added |
| Lighthouse Investment Partners, LLC | 4,640 | $847.5K | 0.03% | +4,640 | New |
| Victory Capital Management Inc | 4,776 | $872.3K | 0.00% | +36+0.8% | Added |
| Odyssean, LLC | 4,983 | $910.1K | 0.65% | +4,983 | New |
| Yarbrough Capital, LLC | 5,054 | $923.1K | 0.03% | 00.0% | Unchanged |
| CWM, LLC | 5,149 | $940.0K | 0.00% | −20.0% | Reduced |
| Teacher Retirement System of Texas | 5,164 | $943.2K | 0.00% | −3,293−38.9% | Reduced |
| Headlands Technologies LLC | 5,187 | $947.4K | 0.08% | +2,613+101.5% | Added |
| Cerity Partners LLC | 5,389 | $984.2K | 0.00% | −15−0.3% | Reduced |
| Prudential Financial Inc | 5,415 | $989.0K | 0.00% | +357+7.1% | Added |
| Cabot Wealth Management Inc | 5,560 | $1.02M | 0.11% | 00.0% | Unchanged |
| Baader Bank INC | 5,823 | $1.06M | 0.09% | +3,708+175.3% | Added |
| Stifel Financial Corp | 5,868 | $1.07M | 0.00% | +361+6.6% | Added |
| Birchview Capital, LP | 6,061 | $1.11M | 0.65% | +61+1.0% | Added |
| AlphaCentric Advisors LLC | 6,088 | $1.11M | 1.11% | +6,088 | New |
| D.A. Davidson & Co. | 6,180 | $1.13M | 0.01% | 00.0% | Unchanged |
| Quantinno Capital Management LP | 6,478 | $1.18M | 0.00% | +3,636+127.9% | Added |
| Pitcairn Wealth Advisors LLC | 6,639 | $1.21M | 0.11% | +6,639 | New |
| Great Lakes Advisors, LLC | 6,765 | $1.24M | 0.01% | +89+1.3% | Added |
| Glenmede Trust Co NA | 6,924 | $1.26M | 0.01% | +6,924 | New |
| Oppenheimer & Co Inc | 7,076 | $1.29M | 0.02% | +7,076 | New |
| J. Safra Sarasin Holding AG | 7,383 | $1.35M | 0.02% | −1,514−17.0% | Reduced |
| Martingale Asset Management L P | 7,406 | $1.35M | 0.03% | +3,606+94.9% | Added |