Axsome Therapeutics, Inc.
AXSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001579428
In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Axsome Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 355
- +10 vs. Q2 2025
- Shares held
- 37.2M
- −189.7K (−0.5%) vs. Q2 2025
- Total value
- $4.51B
- +$613.1M (+15.7%) vs. Q2 2025
- New holders
- 49
- 146 more added
- Sold out
- 39
- 104 more reduced
3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 505 | $9.34B |
| Q1 2026 | 410 | $6.41B |
| Q4 2025 | 399 | $6.86B |
| Q3 2025 | 355 | $4.51B |
| Q2 2025 | 348 | $3.95B |
| Q1 2025 | 353 | $4.37B |
| Q4 2024 | 292 | $3.15B |
| Q3 2024 | 280 | $3.48B |
| Q2 2024 | 257 | $3.28B |
| Q1 2024 | 259 | $3.09B |
| Q4 2023 | 245 | $3.07B |
| Q3 2023 | 227 | $2.65B |
| Q2 2023 | 231 | $2.61B |
| Q1 2023 | 197 | $1.97B |
| Q4 2022 | 219 | $2.32B |
| Q3 2022 | 188 | $1.15B |
| Q2 2022 | 174 | $826.7M |
| Q1 2022 | 175 | $787.4M |
| Q4 2021 | 167 | $704.2M |
| Q3 2021 | 171 | $627.3M |
| Q2 2021 | 176 | $1.51B |
| Q1 2021 | 184 | $1.31B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Citigroup Inc | 142,013 | $17.2M | 0.01% | +57,002+67.1% | Added |
| Perceptive Advisors LLC | 148,900 | $18.1M | 0.52% | −49,634−25.0% | Reduced |
| Renaissance Technologies LLC | 150,000 | $18.2M | 0.02% | +11,300+8.1% | Added |
| Vestal Point Capital, LP | 150,000 | $18.2M | 0.83% | +150,000 | New |
| First Turn Management, LLC | 152,614 | $18.5M | 2.78% | +8,214+5.7% | Added |
| Squarepoint Ops LLC | 155,000 | $18.8M | 0.04% | −8,000−4.9% | Reduced |
| Citadel Advisors LLC | 158,406 | $19.2M | 0.02% | +144,788+1,063.2% | Added |
| Raymond James Financial Inc | 158,689 | $19.3M | 0.01% | −2,723−1.7% | Reduced |
| Rhenman & Partners Asset Management AB | 172,800 | $21.0M | 2.32% | +82,000+90.3% | Added |
| BNP Paribas Arbitrage, SA | 190,106 | $23.1M | 0.02% | +3,669+2.0% | Added |
| MetLife Investment Management | 197,318 | $24.0M | 0.12% | +13,154+7.1% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 209,069 | $25.4M | 0.08% | −15,652−7.0% | Reduced |
| UBS Group AG | 212,451 | $25.8M | 0.01% | −383,004−64.3% | Reduced |
| Driehaus Capital Management LLC | 223,408 | $27.1M | 0.19% | +128+0.1% | Added |
| Goldman Sachs Group Inc | 224,139 | $27.2M | 0.00% | −4,065−1.8% | Reduced |
| JPMorgan Chase & Co | 250,513 | $30.4M | 0.00% | +62,785+33.4% | Added |
| Bank of New York Mellon Corp | 253,263 | $30.8M | 0.01% | +49,631+24.4% | Added |
| T. Rowe Price Investment Management, Inc. | 274,014 | $33.3M | 0.02% | +25,288+10.2% | Added |
| Franklin Resources Inc | 285,598 | $34.7M | 0.01% | +7,088+2.5% | Added |
| Man Group plc | 287,908 | $35.0M | 0.07% | −237,161−45.2% | Reduced |
| Tri Locum Partners LP | 292,137 | $35.5M | 8.16% | +134,276+85.1% | Added |
| Assenagon Asset Management S.A. | 294,771 | $35.8M | 0.05% | +113,811+62.9% | Added |
| D. E. Shaw & Co., Inc. | 296,287 | $36.0M | 0.03% | +95,523+47.6% | Added |
| Nuveen, LLC | 298,341 | $36.2M | 0.01% | +15,370+5.4% | Added |
| Qube Research & Technologies Ltd | 325,626 | $39.5M | 0.06% | −65,991−16.9% | Reduced |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 326,318 | $39.6M | 3.06% | 00.0% | Unchanged |
| Loomis Sayles & Co L P | 330,125 | $40.1M | 0.05% | +52,660+19.0% | Added |
| Woodline Partners LP | 331,864 | $40.3M | 0.19% | +733+0.2% | Added |
| Hood River Capital Management LLC | 359,957 | $43.7M | 0.52% | −11,147−3.0% | Reduced |
| Bank of America Corp | 361,261 | $43.9M | 0.00% | −392,168−52.1% | Reduced |
| Pictet Asset Management Holding SA | 362,138 | $44.0M | 0.04% | −49,712−12.1% | Reduced |
| Principal Financial Group Inc | 368,434 | $44.7M | 0.02% | +12,923+3.6% | Added |
| Marshall Wace, LLP | 378,024 | $45.9M | 0.05% | +321,308+566.5% | Added |
| Charles Schwab Investment Management Inc | 382,047 | $46.4M | 0.01% | +25,396+7.1% | Added |
| Sofinnova Investments, Inc. | 393,499 | $47.8M | 2.93% | +299,889+320.4% | Added |
| Northern Trust Corp | 409,535 | $49.7M | 0.01% | +1410.0% | Added |
| Morgan Stanley | 409,580 | $49.7M | 0.00% | −38,339−8.6% | Reduced |
| Adage Capital Partners GP, L.L.C. | 445,000 | $54.0M | 0.09% | −2,000−0.4% | Reduced |
| BVF Inc | 486,757 | $59.1M | 2.40% | −1,203,464−71.2% | Reduced |
| PFM Health Sciences, LP | 530,332 | $64.4M | 5.49% | +47,227+9.8% | Added |
| OrbiMed Advisors LLC | 531,800 | $64.6M | 1.55% | +103,900+24.3% | Added |
| Alethea Capital Management, LLC | 670,883 | $81.5M | 52.44% | +3,515+0.5% | Added |
| Eventide Asset Management, LLC | 746,398 | $90.6M | 1.49% | +20,726+2.9% | Added |
| Fairmount Funds Management LLC | 815,176 | $99.0M | 8.91% | 00.0% | Unchanged |
| Deep Track Capital, LP | 900,000 | $109.3M | 3.05% | +98,629+12.3% | Added |
| FMR LLC | 927,883 | $112.7M | 0.01% | −48,847−5.0% | Reduced |
| State Street Corp | 942,960 | $114.5M | 0.00% | −15,543−1.6% | Reduced |
| Invesco Ltd. | 990,557 | $120.3M | 0.02% | +419,008+73.3% | Added |
| Geode Capital Management, LLC | 997,700 | $121.2M | 0.01% | +8,247+0.8% | Added |
| Price T Rowe Associates Inc | 1,037,448 | $126.0M | 0.01% | +424,705+69.3% | Added |
| Macquarie Group Ltd | 1,084,536 | $131.7M | 0.15% | −53,212−4.7% | Reduced |
| RTW Investments, LP | 1,118,883 | $135.9M | 1.67% | −398,020−26.2% | Reduced |
| Wellington Management Group LLP | 1,334,560 | $162.1M | 0.03% | +609,516+84.1% | Added |
| BlackRock, Inc. | 3,790,929 | $460.4M | 0.01% | −44,061−1.1% | Reduced |
| Vanguard Group Inc | 4,180,646 | $507.7M | 0.01% | +235,626+6.0% | Added |
| Bridgewater Associates, LP | 0 | $0 | 0.00% | −107,292−100.0% | Sold out |
| Avidity Partners Management LP | 0 | $0 | 0.00% | −94,500−100.0% | Sold out |
| Candriam Luxembourg S.C.A. | 0 | $0 | 0.00% | −76,727−100.0% | Sold out |
| Affinity Asset Advisors, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Schroder Investment Management Group | 0 | $0 | 0.00% | −37,481−100.0% | Sold out |
| Point72 Europe (London) LLP | 0 | $0 | 0.00% | −33,824−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −25,037−100.0% | Sold out |
| Magnetar Financial LLC | 0 | $0 | 0.00% | −20,315−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −16,459−100.0% | Sold out |
| Winton Group Ltd | 0 | $0 | 0.00% | −9,555−100.0% | Sold out |
| Virtue Capital Management, LLC | 0 | $0 | 0.00% | −6,807−100.0% | Sold out |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −6,400−100.0% | Sold out |
| Allianz Asset Management GmbH | 0 | $0 | 0.00% | −6,300−100.0% | Sold out |
| Knott David M Jr | 0 | $0 | 0.00% | −6,000−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −5,000−100.0% | Sold out |
| Aigen Investment Management, LP | 0 | $0 | 0.00% | −4,063−100.0% | Sold out |
| Polen Capital Management LLC | 0 | $0 | 0.00% | −3,232−100.0% | Sold out |
| Qsemble Capital Management, LP | 0 | $0 | 0.00% | −2,681−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −2,500−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −2,490−100.0% | Sold out |
| Mount Yale Investment Advisors, LLC | 0 | $0 | 0.00% | −2,366−100.0% | Sold out |
| NEOS Investment Management LLC | 0 | $0 | 0.00% | −2,327−100.0% | Sold out |
| Tema ETFs LLC | 0 | $0 | 0.00% | −2,327−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −2,228−100.0% | Sold out |
| Whalen Wealth Management Inc. | 0 | $0 | 0.00% | −2,168−100.0% | Sold out |
| Virginia Retirement Systems Et Al | 0 | $0 | 0.00% | −2,100−100.0% | Sold out |
| Marex Group plc | 0 | $0 | 0.00% | −2,062−100.0% | Sold out |
| Options Solutions, LLC | 0 | $0 | 0.00% | −2,022−100.0% | Sold out |
| Soleus Capital Management, L.P. | 0 | $0 | 0.00% | −2,000−100.0% | Sold out |
| Raiffeisen Bank International AG | 0 | $0 | 0.00% | −600−100.0% | Sold out |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −289−100.0% | Sold out |
| Transce3nd, LLC | 0 | $0 | 0.00% | −209−100.0% | Sold out |
| State of Wyoming | 0 | $0 | 0.00% | −146−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −37−100.0% | Sold out |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | 0.00% | −37−100.0% | Sold out |
| Riggs Asset Managment Co. Inc. | 0 | $0 | 0.00% | −27−100.0% | Sold out |
| Bryn Mawr Trust Co | 0 | $0 | 0.00% | −16−100.0% | Sold out |
| Twin Peaks Wealth Advisors, LLC | 0 | $0 | 0.00% | −10−100.0% | Sold out |
| Wolff Wiese Magana LLC | 0 | $0 | 0.00% | −10−100.0% | Sold out |
| Norges Bank | – | – | – | – | Not filed |
| CIBC World Markets Corp | – | – | – | – | Not filed |
| Avantax Advisory Services, Inc. | – | – | – | – | Not filed |