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Axsome Therapeutics, Inc.

AXSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001579428

In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Axsome Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
355
+10 vs. Q2 2025
Shares held
37.2M
−189.7K (−0.5%) vs. Q2 2025
Total value
$4.51B
+$613.1M (+15.7%) vs. Q2 2025
New holders
49
146 more added
Sold out
39
104 more reduced

3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 355 institutions
Q1 2021: 184 institutionsQ2 2021: 176 institutionsQ3 2021: 171 institutionsQ4 2021: 167 institutionsQ1 2022: 175 institutionsQ2 2022: 174 institutionsQ3 2022: 188 institutionsQ4 2022: 219 institutionsQ1 2023: 197 institutionsQ2 2023: 231 institutionsQ3 2023: 227 institutionsQ4 2023: 245 institutionsQ1 2024: 259 institutionsQ2 2024: 257 institutionsQ3 2024: 280 institutionsQ4 2024: 292 institutionsQ1 2025: 353 institutionsQ2 2025: 348 institutionsQ3 2025: 355 institutionsQ4 2025: 399 institutionsQ1 2026: 410 institutionsQ2 2026: 505 institutions
Value heldQ3 2025: $4.51B
Q1 2021: $1.31BQ2 2021: $1.51BQ3 2021: $627.3MQ4 2021: $704.2MQ1 2022: $787.4MQ2 2022: $826.7MQ3 2022: $1.15BQ4 2022: $2.32BQ1 2023: $1.97BQ2 2023: $2.61BQ3 2023: $2.65BQ4 2023: $3.07BQ1 2024: $3.09BQ2 2024: $3.28BQ3 2024: $3.48BQ4 2024: $3.15BQ1 2025: $4.37BQ2 2025: $3.95BQ3 2025: $4.51BQ4 2025: $6.86BQ1 2026: $6.41BQ2 2026: $9.34B
Institutions holding AXSM and their total value by quarter
QuarterHoldersValue
Q2 2026505$9.34B
Q1 2026410$6.41B
Q4 2025399$6.86B
Q3 2025355$4.51B
Q2 2025348$3.95B
Q1 2025353$4.37B
Q4 2024292$3.15B
Q3 2024280$3.48B
Q2 2024257$3.28B
Q1 2024259$3.09B
Q4 2023245$3.07B
Q3 2023227$2.65B
Q2 2023231$2.61B
Q1 2023197$1.97B
Q4 2022219$2.32B
Q3 2022188$1.15B
Q2 2022174$826.7M
Q1 2022175$787.4M
Q4 2021167$704.2M
Q3 2021171$627.3M
Q2 2021176$1.51B
Q1 2021184$1.31B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding AXSM in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Tortoise Investment Management, LLC2,136$259.4K0.02%00.0%Unchanged
Invst, LLC2,140$259.9K0.03%+26+1.2%Added
Brinker Capital Investments, LLC2,189$265.9K0.00%+53+2.5%Added
McAdam, LLC2,198$266.9K0.01%+2+0.1%Added
EntryPoint Capital, LLC2,263$274.8K0.11%+176+8.4%Added
HRT Financial LP2,281$277.0K0.00%+2,281New
O'Shaughnessy Asset Management, LLC2,330$283.0K0.00%+2,330New
Lombard Odier Asset Management (USA) Corp2,379$288.9K0.07%−27−1.1%Reduced
Moors & Cabot, Inc.2,380$289.1K0.01%+50+2.1%Added
National Asset Management, Inc.2,473$300.3K0.01%+2+0.1%Added
Freestone Grove Partners LP2,494$302.9K0.00%+2,494New
Headlands Technologies LLC2,574$312.6K0.02%+2,476+2,526.5%Added
Graham Capital Management, L.P.2,607$316.6K0.01%−1,777−40.5%Reduced
NBC Securities, Inc.2,670$324.3K0.02%+60+2.3%Added
Fiduciary Family Office, LLC2,670$324.3K0.09%+2,670New
SRS Capital Advisors, Inc.2,707$328.8K0.00%+2,640+3,940.3%Added
Quantinno Capital Management LP2,842$345.2K0.00%+668+30.7%Added
Profund Advisors LLC3,122$379.2K0.01%−941−23.2%Reduced
Xponance, Inc.3,189$387.3K0.00%+35+1.1%Added
Point72 Hong Kong Ltd3,203$389.0K0.02%+3,203New
Ameritas Investment Partners, Inc.3,381$410.6K0.01%−751−18.2%Reduced
Mackenzie Financial Corp3,382$410.7K0.00%+1,097+48.0%Added
Old North State Wealth Management, LLC3,450$419.0K0.20%00.0%Unchanged
Forbes J M & Co LLP3,704$449.9K0.04%00.0%Unchanged
Public Employees Retirement Association of Colorado3,704$450.0K0.00%00.0%Unchanged
Leonteq Securities AG3,737$453.9K0.02%−48−1.3%Reduced
Intrust Bank NA3,764$457.1K0.04%+889+30.9%Added
Pathstone Holdings, LLC3,799$461.4K0.00%+537+16.5%Added
Martingale Asset Management L P3,800$461.5K0.01%−10.0%Reduced
Farallon Capital Management, L.L.C.4,000$485.8K0.00%00.0%Unchanged
Mirador Capital Partners LP4,000$485.8K0.07%00.0%Unchanged
Aries Wealth Management4,000$485.8K0.11%00.0%Unchanged
Toroso Investments, LLC4,021$488.4K0.00%−204−4.8%Reduced
Virtus Investment Advisers, Inc.4,183$508.0K0.15%00.0%Unchanged
Goodwin Investment Advisory4,241$515.1K0.55%00.0%Unchanged
CIBC Bancorp USA Inc.4,314$523.9K0.00%+4,314New
Cornerstone Select Advisors, LLC4,375$531.3K0.39%00.0%Unchanged
Lion Street Advisors, LLC14,677$565.1K0.20%+5,619+62.0%Added
Victory Capital Management Inc4,740$575.7K0.00%−83−1.7%Reduced
Gsa Capital Partners LLP4,767$579.0K0.05%+4,767New
Values First Advisors, Inc.4,882$592.9K0.32%−227−4.4%Reduced
Henshaw Capital LLC5,036$611.6K0.02%−1,835−26.7%Reduced
Legato Capital Management LLC5,051$613.4K0.07%+750+17.4%Added
Yarbrough Capital, LLC5,054$613.8K0.02%00.0%Unchanged
Prudential Financial Inc5,058$614.3K0.00%−17,750−77.8%Reduced
CWM, LLC5,151$626.0K0.00%+2,146+71.4%Added
Cerity Partners LLC5,404$656.3K0.00%−248−4.4%Reduced
Stifel Financial Corp5,507$668.8K0.00%+1,185+27.4%Added
Los Angeles Capital Management LLC5,555$674.7K0.00%+1,131+25.6%Added
Cabot Wealth Management Inc5,560$675.3K0.07%+5,560New
Tocqueville Asset Management L.P.5,650$686.2K0.01%+450+8.7%Added
Rockefeller Capital Management L.P.5,737$696.8K0.00%+5,737New
Millennium Management LLC5,741$697.2K0.00%−24,878−81.3%Reduced
Birchview Capital, LP6,000$728.7K0.55%00.0%Unchanged
Campbell & CO Investment Adviser LLC6,077$738.1K0.06%−3,177−34.3%Reduced
Pitcairn Co6,106$741.6K0.06%−2,407−28.3%Reduced
D.A. Davidson & Co.6,180$750.6K0.00%−475−7.1%Reduced
Perbak Capital Partners LLP6,313$766.7K0.13%+1,585+33.5%Added
Advisor Group Holdings, Inc.6,404$773.6K0.00%+3,189+99.2%Added
Capstone Investment Advisors, LLC6,552$795.7K0.01%+6,552New
Great Lakes Advisors, LLC6,676$810.8K0.01%+306+4.8%Added
Zurcher Kantonalbank (Zurich Cantonalbank)6,989$848.8K0.00%+541+8.4%Added
Glenmede Investment Management, LP7,232$878.3K0.00%−1,055−12.7%Reduced
Dark Forest Capital Management LP7,267$882.6K0.03%−9,624−57.0%Reduced
Brevan Howard Capital Management LP7,334$890.7K0.01%−7,448−50.4%Reduced
Aquatic Capital Management LLC7,426$901.9K0.02%−16,208−68.6%Reduced
MONECO Advisors, LLC7,505$911.5K0.08%00.0%Unchanged
Cynosure Management, LLC7,844$952.7K0.10%00.0%Unchanged
Captrust Financial Advisors7,959$966.6K0.00%+967+13.8%Added
Two Sigma Investments, LP8,207$996.7K0.00%+8,207New
Teachers Retirement System of the State of Kentucky8,328$1.01M0.01%00.0%Unchanged
J. Goldman & Co LP8,401$1.02M0.04%−31,254−78.8%Reduced
Teacher Retirement System of Texas8,457$1.03M0.00%−726−7.9%Reduced
Inceptionr LLC8,659$1.05M0.25%+8,659New
Great West Life Assurance Co8,991$1.06M0.00%+1,586+21.4%Added
ProShare Advisors LLC8,698$1.06M0.00%−1,440−14.2%Reduced
China Universal Asset Management Co., Ltd.8,747$1.06M0.09%−1,142−11.5%Reduced
J. Safra Sarasin Holding AG8,897$1.08M0.02%−10,761−54.7%Reduced
KLP Kapitalforvaltning AS9,000$1.09M0.00%−2,200−19.6%Reduced
Jain Global LLC9,007$1.09M0.01%+9,007New
State Board of Administration of Florida Retirement System9,064$1.10M0.00%−18−0.2%Reduced
B. Metzler seel. Sohn & Co. AG9,241$1.12M0.01%00.0%Unchanged
HighVista Strategies LLC9,348$1.14M0.28%−1,561−14.3%Reduced
Trexquant Investment LP9,521$1.16M0.01%+9,521New
Cetera Investment Advisers9,668$1.17M0.00%+2,448+33.9%Added
Resources Investment Advisors, LLC.9,805$1.19M0.01%+496+5.3%Added
Arizona State Retirement System10,196$1.24M0.01%+258+2.6%Added
Erste Asset Management GmbH11,000$1.29M0.01%00.0%Unchanged
Ieq Capital, LLC10,820$1.31M0.00%+2,972+37.9%Added
Quantbot Technologies LP10,877$1.32M0.04%−7,717−41.5%Reduced
Royal Bank of Canada11,055$1.34M0.00%+3,414+44.7%Added
Police & Firemen's Retirement System of New Jersey11,202$1.36M0.01%+1,934+20.9%Added
Handelsbanken Fonder AB11,400$1.39M0.00%+600+5.6%Added
STRS Ohio11,900$1.45M0.01%−200−1.7%Reduced
Oak Ridge Investments LLC12,065$1.47M0.09%−241−2.0%Reduced
SG Americas Securities, LLC12,097$1.47M0.01%+5,368+79.8%Added
Engineers Gate Manager LP12,178$1.48M0.02%−4,478−26.9%Reduced
Guggenheim Capital LLC12,517$1.52M0.01%+3,065+32.4%Added
Simplex Trading, LLC12,576$1.53M0.03%−743−5.6%Reduced
Comerica Bank12,758$1.55M0.01%+9,362+275.7%Added