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Applied Therapeutics, Inc.

APLTDelisted Feb 3, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001697532

Applied Therapeutics, Inc. was delisted on Feb 3, 2026; its insiders filed their last Form 4 on Feb 4, 2026; 52 institutions reported holding it in 13F filings for Q4 2025, worth $5.93M in total; no superinvestor held it.

13F holders, Q4 2025

Institutional positions in Applied Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

APLT is no longer listed, so this page shows Q4 2025. 13F filings for later quarters list far fewer holders.

Institutional holders
52
−16 vs. Q3 2025
Shares held
58.9M
−35.8M (−37.8%) vs. Q3 2025
Total value
$5.93M
−$51.2M (−89.6%) vs. Q3 2025
New holders
9
13 more added
Sold out
25
19 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 52 institutions
Q1 2021: 67 institutionsQ2 2021: 69 institutionsQ3 2021: 70 institutionsQ4 2021: 69 institutionsQ1 2022: 71 institutionsQ2 2022: 53 institutionsQ3 2022: 44 institutionsQ4 2022: 38 institutionsQ1 2023: 36 institutionsQ2 2023: 40 institutionsQ3 2023: 55 institutionsQ4 2023: 83 institutionsQ1 2024: 89 institutionsQ2 2024: 94 institutionsQ3 2024: 126 institutionsQ4 2024: 119 institutionsQ1 2025: 90 institutionsQ2 2025: 75 institutionsQ3 2025: 70 institutionsQ4 2025: 52 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2025: $5.93M
Q1 2021: $278.6MQ2 2021: $319.3MQ3 2021: $250.9MQ4 2021: $133.6MQ1 2022: $26.0MQ2 2022: $25.3MQ3 2022: $21.1MQ4 2022: $15.1MQ1 2023: $15.6MQ2 2023: $40.3MQ3 2023: $107.0MQ4 2023: $205.8MQ1 2024: $638.6MQ2 2024: $481.8MQ3 2024: $960.9MQ4 2024: $98.5MQ1 2025: $51.8MQ2 2025: $27.4MQ3 2025: $57.2MQ4 2025: $5.93MQ1 2026: $0Q2 2026: $0
Institutions holding APLT and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 202552$5.93M
Q3 202570$57.2M
Q2 202575$27.4M
Q1 202590$51.8M
Q4 2024119$98.5M
Q3 2024126$960.9M
Q2 202494$481.8M
Q1 202489$638.6M
Q4 202383$205.8M
Q3 202355$107.0M
Q2 202340$40.3M
Q1 202336$15.6M
Q4 202238$15.1M
Q3 202244$21.1M
Q2 202253$25.3M
Q1 202271$26.0M
Q4 202169$133.6M
Q3 202170$250.9M
Q2 202169$319.3M
Q1 202167$278.6M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Applied Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding APLT in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Royal Bank of Canada852$00.00%−201,960−99.6%Reduced
Barclays PLC1$00.00%−5,264−100.0%Reduced
Federation des caisses Desjardins du Quebec84$80.00%00.0%Unchanged
FMR LLC184$180.00%−17,298−98.9%Reduced
Optiver Holding B.V.427$430.00%+427New
Rhumbline Advisers544$540.00%00.0%Unchanged
SBI Securities Co., Ltd.788$790.00%−35−4.3%Reduced
BNP Paribas Arbitrage, SA2,974$2970.00%−501−14.4%Reduced
Bank of America Corp3,109$3110.00%−8,561−73.4%Reduced
Quest Partners LLC4,661$4660.00%00.0%Unchanged
Perennial Investment Advisors, LLC11,600$1.16K0.00%00.0%Unchanged
JPMorgan Chase & Co12,064$1.21K0.00%+4,433+58.1%Added
AQR Capital Management LLC13,413$1.34K0.00%−96,274−87.8%Reduced
Point72 Asset Management, L.P.17,020$1.70K0.00%+17,020New
Cresset Asset Management, LLC17,091$1.71K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)19,675$1.97K0.00%−14,680−42.7%Reduced
Adams Wealth Management38,637$3.86K0.00%00.0%Unchanged
CacheTech Inc.38,637$3.86K0.00%00.0%Unchanged
SG Americas Securities, LLC41,748$4.00K0.00%+25,344+154.5%Added
Group One Trading, L.P.48,675$4.87K0.00%−26,586−35.3%Reduced
Sphera Funds Management Ltd.50,000$5.00K0.00%00.0%Unchanged
Susquehanna International Group, LLP52,692$5.27K0.00%−424,465−89.0%Reduced
Tudor Investment Corp Et Al57,454$5.75K0.00%00.0%Unchanged
Roble, Belko & Company, Inc65,571$7.00K0.00%+34,730+112.6%Added
Goldman Sachs Group Inc146,219$14.6K0.00%−8,922−5.8%Reduced
Citigroup Inc163,449$16.3K0.00%+156,608+2,289.3%Added
Change Path, LLC169,974$17.0K0.00%+69,962+70.0%Added
Morgan Stanley178,474$17.8K0.00%−534,841−75.0%Reduced
GTS Securities LLC200,009$20.0K0.00%+200,009New
Rockefeller Capital Management L.P.241,897$24.2K0.00%−150,000−38.3%Reduced
Northern Trust Corp245,144$24.5K0.00%+71,429+41.1%Added
Bank of New York Mellon Corp253,575$25.4K0.00%+174,157+219.3%Added
Equitec Proprietary Markets, LLC300,600$30.1K0.14%+300,600New
Hennion & Walsh Asset Management, Inc.327,137$32.7K0.00%+44,289+15.7%Added
Marshall Wace, LLP337,389$33.7K0.00%−2,205,299−86.7%Reduced
Lynx1 Capital Management LP410,500$41.0K0.01%+410,500New
Virtu Financial LLC496,288$50.0K0.00%+445,271+872.8%Added
State Street Corp558,178$55.8K0.00%+39,660+7.6%Added
Graham Capital Management, L.P.572,759$57.3K0.00%+572,759New
Deutsche Bank AG622,226$62.2K0.00%00.0%Unchanged
UBS Group AG718,924$71.9K0.00%−1,186,701−62.3%Reduced
Millennium Management LLC1,051,846$105.2K0.00%−855,368−44.8%Reduced
Adage Capital Partners GP, L.L.C.1,211,629$121.2K0.00%−1,000,000−45.2%Reduced
Geode Capital Management, LLC1,492,903$149.3K0.00%+214,747+16.8%Added
Jane Street Group, LLC2,087,404$208.7K0.00%+2,087,404New
Renaissance Technologies LLC2,706,156$270.6K0.00%+2,706,156New
Pathstone Holdings, LLC2,643,540$305.1K0.00%00.0%Unchanged
BlackRock, Inc.3,251,462$325.1K0.00%−592,271−15.4%Reduced
Deltec Asset Management LLC3,847,449$384.7K0.06%+3,847,449New
Knoll Capital Management, LLC6,050,000$605.0K0.28%−1,749,687−22.4%Reduced
Vanguard Group Inc6,353,018$635.3K0.00%+1,250,329+24.5%Added
T. Rowe Price Investment Management, Inc.21,747,844$2.17M0.00%+344,544+1.6%Added
Vestal Point Capital, LP0$00.00%−14,250,000−100.0%Sold out
Propel Bio Management, LLC0$00.00%−11,285,420−100.0%Sold out
Simplify Asset Management Inc.0$00.00%−4,487,505−100.0%Sold out
The PNC Financial Services Group, Inc.0$00.00%−2,901,184−100.0%Sold out
Rock Springs Capital Management LP0$00.00%−2,075,991−100.0%Sold out
Franklin Resources Inc0$00.00%−2,003,338−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−1,167,269−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−673,764−100.0%Sold out
Birchview Capital, LP0$00.00%−225,000−100.0%Sold out
Two Sigma Investments, LP0$00.00%−198,933−100.0%Sold out
Squarepoint Ops LLC0$00.00%−158,865−100.0%Sold out
Scientech Research LLC0$00.00%−105,110−100.0%Sold out
HRT Financial LP0$00.00%−94,870−100.0%Sold out
Ethic Inc.0$00.00%−27,193−100.0%Sold out
China Universal Asset Management Co., Ltd.0$00.00%−25,243−100.0%Sold out
XTX Topco Ltd0$00.00%−23,579−100.0%Sold out
Cerity Partners LLC0$00.00%−16,803−100.0%Sold out
JustInvest LLC0$00.00%−16,244−100.0%Sold out
Stratos Wealth Advisors, LLC0$00.00%−10,500−100.0%Sold out
Beaumont Capital Management, LLC0$00.00%−10,403−100.0%Sold out
Mirae Asset Global Investments Co., Ltd.0$00.00%−5,568−100.0%Sold out
Capital Advisors, Ltd. LLC0$00.00%−2,367−100.0%Sold out
Sunbelt Securities, Inc.0$00.00%−1,000−100.0%Sold out
Parallel Advisors, LLC0$00.00%−100−100.0%Sold out
CWM, LLC0$00.00%−376−100.0%Sold out
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Wolverine Trading, LLC––––Not filed