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Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Annexon, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
217
+51 vs. Q4 2025
Shares held
155.9M
+26.8M (+20.8%) vs. Q4 2025
Total value
$863.7M
+$215.6M (+33.3%) vs. Q4 2025
New holders
66
87 more added
Sold out
15
49 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 217 institutions
Q1 2021: 72 institutionsQ2 2021: 74 institutionsQ3 2021: 82 institutionsQ4 2021: 97 institutionsQ1 2022: 100 institutionsQ2 2022: 78 institutionsQ3 2022: 72 institutionsQ4 2022: 84 institutionsQ1 2023: 100 institutionsQ2 2023: 95 institutionsQ3 2023: 93 institutionsQ4 2023: 99 institutionsQ1 2024: 127 institutionsQ2 2024: 140 institutionsQ3 2024: 142 institutionsQ4 2024: 153 institutionsQ1 2025: 148 institutionsQ2 2025: 129 institutionsQ3 2025: 144 institutionsQ4 2025: 168 institutionsQ1 2026: 217 institutionsQ2 2026: 216 institutions
Value heldQ1 2026: $863.7M
Q1 2021: $1.04BQ2 2021: $873.7MQ3 2021: $708.6MQ4 2021: $445.7MQ1 2022: $105.9MQ2 2022: $144.9MQ3 2022: $292.3MQ4 2022: $243.3MQ1 2023: $207.6MQ2 2023: $190.0MQ3 2023: $126.0MQ4 2023: $365.7MQ1 2024: $679.4MQ2 2024: $526.9MQ3 2024: $651.8MQ4 2024: $574.6MQ1 2025: $192.1MQ2 2025: $238.7MQ3 2025: $309.2MQ4 2025: $687.2MQ1 2026: $863.7MQ2 2026: $1.02B
Institutions holding ANNX and their total value by quarter
QuarterHoldersValue
Q2 2026216$1.02B
Q1 2026217$863.7M
Q4 2025168$687.2M
Q3 2025144$309.2M
Q2 2025129$238.7M
Q1 2025148$192.1M
Q4 2024153$574.6M
Q3 2024142$651.8M
Q2 2024140$526.9M
Q1 2024127$679.4M
Q4 202399$365.7M
Q3 202393$126.0M
Q2 202395$190.0M
Q1 2023100$207.6M
Q4 202284$243.3M
Q3 202272$292.3M
Q2 202278$144.9M
Q1 2022100$105.9M
Q4 202197$445.7M
Q3 202182$708.6M
Q2 202174$873.7M
Q1 202172$1.04B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q4 2025.

Institutions holding ANNX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Qube Research & Technologies Ltd3,114,314$17.3M0.02%+732,835+30.8%Added
Geode Capital Management, LLC3,377,823$18.7M0.00%+474,927+16.4%Added
Ameriprise Financial Inc3,449,121$19.1M0.00%−899,661−20.7%Reduced
Balyasny Asset Management LLC3,886,909$21.5M0.04%+587,653+17.8%Added
Siren, L.L.C.3,958,646$21.9M0.61%+3,958,646New
Nuveen, LLC4,246,330$23.5M0.01%+1,331,006+45.7%Added
Bank of America Corp4,259,995$23.6M0.00%+2,654,414+165.3%Added
Adage Capital Partners GP, L.L.C.4,300,000$23.8M0.04%−1,200,000−21.8%Reduced
Mak Capital One LLC4,724,043$26.2M4.33%+1,765,516+59.7%Added
Bellevue Group AG5,157,290$28.6M0.68%00.0%Unchanged
Bain Capital Life Sciences Investors, LLC5,212,674$28.9M2.60%−36,395−0.7%Reduced
Vanguard Capital Management LLC5,956,589$33.0M0.00%+5,956,589New
State Street Corp6,919,255$38.3M0.00%+2,267,070+48.7%Added
BVF Inc8,698,173$48.2M1.54%−429,907−4.7%Reduced
FMR LLC10,635,648$58.9M0.00%+413,178+4.0%Added
BlackRock, Inc.10,938,509$60.6M0.00%+1,978,075+22.1%Added
Redmile Group, LLC14,549,768$80.6M5.34%+4,499,124+44.8%Added
Sphera Funds Management Ltd.0$00.00%−1,316,212−100.0%Sold out
SummitTX Capital, L.P.0$00.00%−438,497−100.0%Sold out
Jump Financial, LLC0$00.00%−122,858−100.0%Sold out
Caption Management, LLC0$00.00%−119,491−100.0%Sold out
Citizens Financial Group Inc0$00.00%−40,000−100.0%Sold out
Pale Fire Capital SE0$00.00%−38,600−100.0%Sold out
Landing Point Financial Group, LLC0$00.00%−34,900−100.0%Sold out
SG Americas Securities, LLC0$00.00%−28,071−100.0%Sold out
HSBC Holdings PLC0$00.00%−25,651−100.0%Sold out
Group One Trading, L.P.0$00.00%−14,184−100.0%Sold out
Simplex Trading, LLC0$00.00%−10,268−100.0%Sold out
Amalgamated Bank0$00.00%−3,144−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−352−100.0%Sold out
Assetmark, Inc0$00.00%−333−100.0%Sold out
Northwestern Mutual Wealth Management Co0$00.00%−4−100.0%Sold out
Vanguard Group Inc––––Not filed
Comerica Bank––––Not filed