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Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Annexon, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
129
−19 vs. Q1 2025
Shares held
99.7M
−42.6K (0.0%) vs. Q1 2025
Total value
$238.7M
+$46.6M (+24.2%) vs. Q1 2025
New holders
18
51 more added
Sold out
37
34 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 129 institutions
Q1 2021: 72 institutionsQ2 2021: 74 institutionsQ3 2021: 82 institutionsQ4 2021: 97 institutionsQ1 2022: 100 institutionsQ2 2022: 78 institutionsQ3 2022: 72 institutionsQ4 2022: 84 institutionsQ1 2023: 100 institutionsQ2 2023: 95 institutionsQ3 2023: 93 institutionsQ4 2023: 99 institutionsQ1 2024: 127 institutionsQ2 2024: 140 institutionsQ3 2024: 142 institutionsQ4 2024: 153 institutionsQ1 2025: 148 institutionsQ2 2025: 129 institutionsQ3 2025: 144 institutionsQ4 2025: 168 institutionsQ1 2026: 217 institutionsQ2 2026: 216 institutions
Value heldQ2 2025: $238.7M
Q1 2021: $1.04BQ2 2021: $873.7MQ3 2021: $708.6MQ4 2021: $445.7MQ1 2022: $105.9MQ2 2022: $144.9MQ3 2022: $292.3MQ4 2022: $243.3MQ1 2023: $207.6MQ2 2023: $190.0MQ3 2023: $126.0MQ4 2023: $365.7MQ1 2024: $679.4MQ2 2024: $526.9MQ3 2024: $651.8MQ4 2024: $574.6MQ1 2025: $192.1MQ2 2025: $238.7MQ3 2025: $309.2MQ4 2025: $687.2MQ1 2026: $863.7MQ2 2026: $1.02B
Institutions holding ANNX and their total value by quarter
QuarterHoldersValue
Q2 2026216$1.02B
Q1 2026217$863.7M
Q4 2025168$687.2M
Q3 2025144$309.2M
Q2 2025129$238.7M
Q1 2025148$192.1M
Q4 2024153$574.6M
Q3 2024142$651.8M
Q2 2024140$526.9M
Q1 2024127$679.4M
Q4 202399$365.7M
Q3 202393$126.0M
Q2 202395$190.0M
Q1 2023100$207.6M
Q4 202284$243.3M
Q3 202272$292.3M
Q2 202278$144.9M
Q1 2022100$105.9M
Q4 202197$445.7M
Q3 202182$708.6M
Q2 202174$873.7M
Q1 202172$1.04B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q1 2025.

Institutions holding ANNX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Charles Schwab Investment Management Inc728,389$1.75M0.00%+2,637+0.4%Added
Northern Trust Corp743,224$1.78M0.00%−282,701−27.6%Reduced
Renaissance Technologies LLC777,900$1.87M0.00%−384,537−33.1%Reduced
Walleye Capital LLC794,639$1.91M0.02%−8,274−1.0%Reduced
Morgan Stanley832,540$2.00M0.00%+131,184+18.7%Added
Kennedy Capital Management, Inc.855,573$2.05M0.05%−19,153−2.2%Reduced
Dimensional Fund Advisors LP889,863$2.14M0.00%−97,016−9.8%Reduced
Massachusetts Financial Services Co987,513$2.37M0.00%−32,904−3.2%Reduced
Sirios Capital Management L P989,577$2.37M0.34%+220,891+28.7%Added
Woodline Partners LP1,053,709$2.53M0.01%−1,060,987−50.2%Reduced
Mutual of America Capital Management LLC1,078,961$2.59M0.03%+48,278+4.7%Added
Bank of America Corp1,452,795$3.49M0.00%+414,071+39.9%Added
Goldman Sachs Group Inc1,630,649$3.91M0.00%+789,067+93.8%Added
Sphera Funds Management Ltd.1,764,387$4.23M1.11%00.0%Unchanged
State Street Corp1,980,984$4.75M0.00%−58,842−2.9%Reduced
Ameriprise Financial Inc2,166,178$5.20M0.00%−1,819,117−45.6%Reduced
Geode Capital Management, LLC2,284,773$5.48M0.00%+39,763+1.8%Added
Logos Global Management LP2,410,000$5.78M0.77%−1,590,000−39.8%Reduced
Millennium Management LLC2,514,134$6.03M0.01%+2,338,831+1,334.2%Added
Candriam Luxembourg S.C.A.2,534,230$6.08M0.04%00.0%Unchanged
Polygon Management Ltd.2,810,000$6.74M1.22%+160,000+6.0%Added
Sio Capital Management, LLC4,095,764$9.83M3.94%+697,978+20.5%Added
Bellevue Group AG5,157,290$12.4M0.27%00.0%Unchanged
Bain Capital Life Sciences Investors, LLC5,249,069$12.6M1.58%00.0%Unchanged
Vanguard Group Inc5,366,039$12.9M0.00%−13,620−0.3%Reduced
Redmile Group, LLC6,300,644$15.1M1.61%00.0%Unchanged
BVF Inc7,000,000$16.8M0.60%00.0%Unchanged
BlackRock, Inc.7,962,368$19.1M0.00%−564,138−6.6%Reduced
FMR LLC15,695,226$37.7M0.00%+2,432,898+18.3%Added
Wellington Management Group LLP0$00.00%−356,480−100.0%Sold out
Syon Capital LLC0$00.00%−144,485−100.0%Sold out
Swiss National Bank0$00.00%−135,000−100.0%Sold out
Squarepoint Ops LLC0$00.00%−132,997−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−96,752−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−81,636−100.0%Sold out
HRT Financial LP0$00.00%−78,100−100.0%Sold out
California State Teachers Retirement System0$00.00%−66,375−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−65,918−100.0%Sold out
SG Americas Securities, LLC0$00.00%−63,161−100.0%Sold out
Jain Global LLC0$00.00%−61,276−100.0%Sold out
XTX Topco Ltd0$00.00%−58,130−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−53,271−100.0%Sold out
Franklin Resources Inc0$00.00%−49,123−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−47,838−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−45,714−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−41,011−100.0%Sold out
Janus Henderson Group PLC0$00.00%−34,500−100.0%Sold out
Shay Capital LLC0$00.00%−35,162−100.0%Sold out
Zurcher Kantonalbank (Zurich Cantonalbank)0$00.00%−34,026−100.0%Sold out
Alpine Global Management, LLC0$00.00%−25,145−100.0%Sold out
Virginia Retirement Systems Et Al0$00.00%−20,600−100.0%Sold out
Arizona State Retirement System0$00.00%−19,875−100.0%Sold out
Teacher Retirement System of Texas0$00.00%−19,462−100.0%Sold out
KLP Kapitalforvaltning AS0$00.00%−19,100−100.0%Sold out
Quantinno Capital Management LP0$00.00%−17,770−100.0%Sold out
Great West Life Assurance Co0$00.00%−14,935−100.0%Sold out
Axq Capital, LP0$00.00%−14,117−100.0%Sold out
LPL Financial LLC0$00.00%−12,926−100.0%Sold out
Catalyst Funds Management Pty Ltd0$00.00%−11,760−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−11,425−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−10,947−100.0%Sold out
Private Wealth Management Group, LLC0$00.00%−654−100.0%Sold out
CIBC Private Wealth Group, LLC0$00.00%−670−100.0%Sold out
Group One Trading, L.P.0$00.00%−438−100.0%Sold out
Parkside Financial Bank & Trust0$00.00%−140−100.0%Sold out
True Wealth Design, LLC0$00.00%−17−100.0%Sold out