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Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Annexon, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
97
+16 vs. Q3 2021
Shares held
38.8M
+748.0K (+2.0%) vs. Q3 2021
Total value
$445.7M
−$262.2M (−37.0%) vs. Q3 2021
New holders
25
33 more added
Sold out
9
23 more reduced

1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 97 institutions
Q1 2021: 72 institutionsQ2 2021: 74 institutionsQ3 2021: 82 institutionsQ4 2021: 97 institutionsQ1 2022: 100 institutionsQ2 2022: 78 institutionsQ3 2022: 72 institutionsQ4 2022: 84 institutionsQ1 2023: 100 institutionsQ2 2023: 95 institutionsQ3 2023: 93 institutionsQ4 2023: 99 institutionsQ1 2024: 127 institutionsQ2 2024: 140 institutionsQ3 2024: 142 institutionsQ4 2024: 153 institutionsQ1 2025: 148 institutionsQ2 2025: 129 institutionsQ3 2025: 144 institutionsQ4 2025: 168 institutionsQ1 2026: 217 institutionsQ2 2026: 216 institutions
Value heldQ4 2021: $445.7M
Q1 2021: $1.04BQ2 2021: $873.7MQ3 2021: $708.6MQ4 2021: $445.7MQ1 2022: $105.9MQ2 2022: $144.9MQ3 2022: $292.3MQ4 2022: $243.3MQ1 2023: $207.6MQ2 2023: $190.0MQ3 2023: $126.0MQ4 2023: $365.7MQ1 2024: $679.4MQ2 2024: $526.9MQ3 2024: $651.8MQ4 2024: $574.6MQ1 2025: $192.1MQ2 2025: $238.7MQ3 2025: $309.2MQ4 2025: $687.2MQ1 2026: $863.7MQ2 2026: $1.02B
Institutions holding ANNX and their total value by quarter
QuarterHoldersValue
Q2 2026216$1.02B
Q1 2026217$863.7M
Q4 2025168$687.2M
Q3 2025144$309.2M
Q2 2025129$238.7M
Q1 2025148$192.1M
Q4 2024153$574.6M
Q3 2024142$651.8M
Q2 2024140$526.9M
Q1 2024127$679.4M
Q4 202399$365.7M
Q3 202393$126.0M
Q2 202395$190.0M
Q1 2023100$207.6M
Q4 202284$243.3M
Q3 202272$292.3M
Q2 202278$144.9M
Q1 2022100$105.9M
Q4 202197$445.7M
Q3 202182$708.6M
Q2 202174$873.7M
Q1 202172$1.04B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q3 2021.

Institutions holding ANNX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Kayne Anderson Rudnick Investment Management LLC2$00.00%+2New
Northwestern Mutual Wealth Management Co15$00.00%+15New
Ellevest, Inc.10$00.00%+10New
Daiwa Securities Group Inc.131$2.00K0.00%00.0%Unchanged
Point72 Hong Kong Ltd188$2.00K0.00%+188New
US Bancorp462$5.00K0.00%+462New
State of Wyoming812$9.00K0.00%+143+21.4%Added
Great West Life Assurance Co923$11.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.1,091$13.0K0.00%00.0%Unchanged
Quantbot Technologies LP1,300$14.0K0.00%+700+116.7%Added
HighMark Wealth Management LLC1,300$15.0K0.01%−415−24.2%Reduced
SG3 Management, LLC2,000$23.0K0.00%+2,000New
Ameritas Investment Partners, Inc.2,169$25.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)3,854$44.0K0.00%+2,698+233.4%Added
Royal Bank of Canada5,974$69.0K0.00%+2,720+83.6%Added
Marshall Wace, LLP6,260$73.0K0.00%+6,260New
Simplex Trading, LLC7,395$84.0K0.00%+7,395New
Legal & General Group Plc7,422$86.0K0.00%+1,343+22.1%Added
Ensign Peak Advisors, Inc8,370$96.0K0.00%+8,370New
Metropolitan Life Insurance Co8,725$100.3K0.00%00.0%Unchanged
Alta Wealth Advisors LLC10,158$117.0K0.07%00.0%Unchanged
SG Americas Securities, LLC10,242$118.0K0.00%−11,258−52.4%Reduced
Victory Capital Management Inc10,389$119.0K0.00%−856−7.6%Reduced
MetLife Investment Management10,674$122.6K0.00%00.0%Unchanged
Invesco Ltd.11,161$128.0K0.00%−1,843−14.2%Reduced
Squarepoint Ops LLC11,453$132.0K0.00%+11,453New
ProShare Advisors LLC12,217$139.0K0.00%+34+0.3%Added
Virtus ETF Advisers LLC12,078$139.0K0.05%+3,035+33.6%Added
Voya Investment Management LLC12,269$141.0K0.00%−61−0.5%Reduced
PDT Partners, LLC12,415$143.0K0.01%+12,415New
Wells Fargo & Company14,022$161.0K0.00%+13,911+12,532.4%Added
HRT Financial LP14,133$162.0K0.00%+14,133New
Credit Suisse AG14,529$166.0K0.00%+14,529New
Walleye Trading LLC15,365$177.0K0.00%+15,365New
American International Group, Inc.16,570$190.0K0.00%−496−2.9%Reduced
Coastal Bridge Advisors, LLC17,000$195.0K0.04%+17,000New
Manufacturers Life Insurance Company, The17,317$201.0K0.00%+358+2.1%Added
Deutsche Bank AG18,944$218.0K0.00%+1,007+5.6%Added
Cna Financial Corp19,710$226.0K0.06%+2,790+16.5%Added
New York State Common Retirement Fund21,982$253.0K0.00%−2,644−10.7%Reduced
Raymond James & Associates22,048$253.0K0.00%00.0%Unchanged
Dimensional Fund Advisors LP28,669$329.0K0.00%+28,669New
DAFNA Capital Management LLC30,796$354.0K0.09%+7,500+32.2%Added
Cubist Systematic Strategies, LLC32,266$371.0K0.00%+25,994+414.4%Added
Verition Fund Management LLC35,000$402.0K0.01%+35,000New
California State Teachers Retirement System36,267$417.0K0.00%+6,888+23.4%Added
Trexquant Investment LP36,340$418.0K0.03%+36,340New
Rhumbline Advisers37,775$434.0K0.00%−506−1.3%Reduced
State of Wisconsin Investment Board40,300$463.0K0.00%00.0%Unchanged
Jump Financial, LLC40,397$464.0K0.03%+40,397New
Alps Advisors Inc44,409$510.0K0.01%−2,574−5.5%Reduced
Susquehanna International Group, LLP45,470$522.0K0.00%+45,470New
Brookfield Asset Management Inc.46,151$530.0K0.00%+33,007+251.1%Added
Swiss National Bank50,600$581.0K0.00%+17,000+50.6%Added
Walleye Capital LLC52,527$604.0K0.02%+52,527New
UBS Group AG54,146$622.0K0.00%+54,146New
Two Sigma Investments, LP55,558$638.0K0.00%+55,558New
Citigroup Inc63,815$733.0K0.00%+55,389+657.4%Added
Rafferty Asset Management, LLC71,681$824.0K0.00%+71,681New
JPMorgan Chase & Co73,540$845.0K0.00%+2,463+3.5%Added
Schroder Investment Management Group84,493$971.0K0.00%+2,262+2.8%Added
TD Asset Management Inc86,073$989.0K0.00%+36,800+74.7%Added
Bank of America Corp96,347$1.11M0.00%+86,616+890.1%Added
Renaissance Technologies LLC100,900$1.16M0.00%+100,900New
Bank of New York Mellon Corp101,280$1.16M0.00%−2,086−2.0%Reduced
Sphera Funds Management Ltd.123,637$1.42M0.17%00.0%Unchanged
Nuveen Asset Management, LLC110,408$1.50M0.00%−8,255−7.0%Reduced
Goldman Sachs Group Inc162,665$1.87M0.00%+130,891+411.9%Added
Charles Schwab Investment Management Inc194,952$2.24M0.00%+4,025+2.1%Added
Alyeska Investment Group, L.P.200,000$2.30M0.03%−3,639−1.8%Reduced
Rhenman & Partners Asset Management AB250,000$2.90M0.19%00.0%Unchanged
Northern Trust Corp294,186$3.38M0.00%+7,252+2.5%Added
Morgan Stanley300,297$3.45M0.00%+247,677+470.7%Added
Millennium Management LLC354,770$4.08M0.00%+343,768+3,124.6%Added
Farallon Capital Management, L.L.C.457,764$5.26M0.03%−699,497−60.4%Reduced
First Light Asset Management, LLC473,700$5.44M0.39%−10,073−2.1%Reduced
Geode Capital Management, LLC480,208$5.52M0.00%+55,165+13.0%Added
Board of Trustees of The Leland Stanford Junior University482,550$5.54M0.35%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)583,913$6.71M0.14%00.0%Unchanged
Massachusetts Financial Services Co714,781$8.21M0.00%−5,354−0.7%Reduced
Point72 Asset Management, L.P.874,752$10.1M0.04%−147,731−14.4%Reduced
NEA Management Company, LLC901,537$10.4M0.21%−1,457,069−61.8%Reduced
Blackstone Group Inc.910,211$10.5M0.03%00.0%Unchanged
Adage Capital Partners GP, L.L.C.959,830$11.0M0.02%−50,000−5.0%Reduced
Vanguard Group Inc1,075,310$12.4M0.00%+54,452+5.3%Added
State Street Corp1,294,182$14.9M0.00%+789,539+156.5%Added
FMR LLC1,340,027$15.4M0.00%−765,395−36.4%Reduced
Citadel Advisors LLC1,477,622$17.0M0.02%−385,001−20.7%Reduced
Satter Management Co., L.P.1,954,978$22.5M22.85%00.0%Unchanged
Federated Hermes, Inc.2,025,600$23.3M0.04%−2,100−0.1%Reduced
Alliancebernstein L.P.2,090,355$24.0M0.01%+373,074+21.7%Added
Pictet Asset Management SA2,158,684$24.8M0.02%+541,450+33.5%Added
BlackRock Inc.2,614,591$30.0M0.00%−264,283−9.2%Reduced
Eventide Asset Management, LLC2,850,000$32.7M0.42%+318,372+12.6%Added
Price T Rowe Associates Inc2,876,667$33.1M0.00%+1,151,996+66.8%Added
Redmile Group, LLC3,228,917$37.1M0.84%−120,268−3.6%Reduced
Bain Capital Life Sciences Investors, LLC3,241,628$37.2M2.95%00.0%Unchanged
Novo Holdings A/S0$00.00%−114,330−100.0%Sold out
AlpInvest Partners B.V.0$00.00%−93,141−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−14,120−100.0%Sold out