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Anaptysbio, Inc

ANAB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001370053

No open-market purchases or sales by Anaptysbio, Inc insiders were filed in the last 90 days; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Anaptysbio, Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
148
−3 vs. Q1 2025
Shares held
36.8M
−3.18M (−8.0%) vs. Q1 2025
Total value
$816.2M
+$73.6M (+9.9%) vs. Q1 2025
New holders
28
45 more added
Sold out
31
55 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 148 institutions
Q1 2021: 122 institutionsQ2 2021: 122 institutionsQ3 2021: 127 institutionsQ4 2021: 136 institutionsQ1 2022: 131 institutionsQ2 2022: 124 institutionsQ3 2022: 114 institutionsQ4 2022: 118 institutionsQ1 2023: 113 institutionsQ2 2023: 116 institutionsQ3 2023: 116 institutionsQ4 2023: 119 institutionsQ1 2024: 133 institutionsQ2 2024: 135 institutionsQ3 2024: 160 institutionsQ4 2024: 136 institutionsQ1 2025: 153 institutionsQ2 2025: 148 institutionsQ3 2025: 166 institutionsQ4 2025: 179 institutionsQ1 2026: 208 institutionsQ2 2026: 213 institutions
Value heldQ2 2025: $816.2M
Q1 2021: $628.6MQ2 2021: $720.6MQ3 2021: $748.8MQ4 2021: $964.4MQ1 2022: $735.4MQ2 2022: $632.6MQ3 2022: $830.6MQ4 2022: $1.02BQ1 2023: $675.4MQ2 2023: $614.9MQ3 2023: $544.5MQ4 2023: $646.4MQ1 2024: $658.1MQ2 2024: $746.6MQ3 2024: $1.13BQ4 2024: $468.9MQ1 2025: $742.8MQ2 2025: $816.2MQ3 2025: $980.2MQ4 2025: $1.42BQ1 2026: $1.55BQ2 2026: $2.03B
Institutions holding ANAB and their total value by quarter
QuarterHoldersValue
Q2 2026213$2.03B
Q1 2026208$1.55B
Q4 2025179$1.42B
Q3 2025166$980.2M
Q2 2025148$816.2M
Q1 2025153$742.8M
Q4 2024136$468.9M
Q3 2024160$1.13B
Q2 2024135$746.6M
Q1 2024133$658.1M
Q4 2023119$646.4M
Q3 2023116$544.5M
Q2 2023116$614.9M
Q1 2023113$675.4M
Q4 2022118$1.02B
Q3 2022114$830.6M
Q2 2022124$632.6M
Q1 2022131$735.4M
Q4 2021136$964.4M
Q3 2021127$748.8M
Q2 2021122$720.6M
Q1 2021122$628.6M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q1 2025.

Institutions holding ANAB in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Voya Investment Management LLC73,005$1.62M0.00%−23,967−24.7%Reduced
Wellington Management Group LLP80,213$1.78M0.00%+4,192+5.5%Added
Invesco Ltd.83,174$1.85M0.00%+61,838+289.8%Added
Sectoral Asset Management Inc83,900$1.86M1.23%+83,900New
Balyasny Asset Management LLC92,852$2.06M0.00%+60,778+189.5%Added
Macquarie Group Ltd93,732$2.08M0.00%00.0%Unchanged
Barclays PLC99,999$2.22M0.00%+43,780+77.9%Added
Squarepoint Ops LLC109,388$2.43M0.01%+109,388New
D. E. Shaw & Co., Inc.112,349$2.49M0.00%−17,305−13.3%Reduced
Citadel Advisors LLC118,286$2.63M0.00%−254,283−68.3%Reduced
Camber Capital Management LP125,000$2.77M0.39%−625,000−83.3%Reduced
Granahan Investment Management Inc131,655$2.92M0.12%−14,836−10.1%Reduced
HighMark Wealth Management LLC145,550$3.23M1.58%+53,550+58.2%Added
Arrowstreet Capital, Limited Partnership150,810$3.35M0.00%+150,810New
Charles Schwab Investment Management Inc157,135$3.49M0.00%+3,779+2.5%Added
Susquehanna International Group, LLP189,327$4.20M0.01%+144,990+327.0%Added
Northern Trust Corp196,263$4.36M0.00%−16,623−7.8%Reduced
Trexquant Investment LP199,242$4.42M0.05%+45,679+29.7%Added
Millennium Management LLC203,542$4.52M0.00%+185,735+1,043.0%Added
Ensign Peak Advisors, Inc215,454$4.78M0.01%00.0%Unchanged
Two Sigma Investments, LP231,369$5.14M0.01%−34,489−13.0%Reduced
JPMorgan Chase & Co247,625$5.50M0.00%+233,325+1,631.6%Added
Renaissance Technologies LLC263,086$5.84M0.01%−75,614−22.3%Reduced
Goldman Sachs Group Inc279,835$6.21M0.00%−742−0.3%Reduced
Two Sigma Advisers, LP290,400$6.45M0.01%+22,300+8.3%Added
Soleus Capital Management, L.P.321,040$7.13M0.49%+218,988+214.6%Added
Nuveen, LLC323,534$7.18M0.00%+267,522+477.6%Added
Franklin Resources Inc354,508$7.87M0.00%+1170.0%Added
Jacobs Levy Equity Management, Inc368,447$8.18M0.03%+351,960+2,134.8%Added
Geode Capital Management, LLC463,358$10.3M0.00%−27,809−5.7%Reduced
683 Capital Management, LLC500,000$11.1M1.13%+304,373+155.6%Added
Woodline Partners LP501,023$11.1M0.06%−290,000−36.7%Reduced
Victory Capital Management Inc532,085$11.8M0.01%+125,655+30.9%Added
Price T Rowe Associates Inc673,171$14.9M0.00%−241,910−26.4%Reduced
Palo Alto Investors LP812,821$18.0M3.84%−207,892−20.4%Reduced
State Street Corp821,031$18.2M0.00%−39,692−4.6%Reduced
Sanofi821,917$18.2M10.38%00.0%Unchanged
Sofinnova Investments, Inc.1,032,362$22.9M1.56%−127,671−11.0%Reduced
Citigroup Inc1,046,488$23.2M0.02%−24,759−2.3%Reduced
Bank of America Corp1,076,799$23.9M0.00%−67,160−5.9%Reduced
UBS Group AG1,272,499$28.2M0.01%+782,226+159.5%Added
Tang Capital Management LLC1,330,879$29.5M1.49%−214,274−13.9%Reduced
Vanguard Group Inc1,537,550$34.1M0.00%+20,225+1.3%Added
BlackRock, Inc.1,786,934$39.7M0.00%−389,664−17.9%Reduced
Morgan Stanley1,869,840$41.5M0.00%+1,365,204+270.5%Added
Point72 Asset Management, L.P.2,474,874$54.9M0.13%+106,504+4.5%Added
First Light Asset Management, LLC3,539,593$78.6M10.19%−1,094,009−23.6%Reduced
EcoR1 Capital, LLC7,880,094$174.9M10.38%00.0%Unchanged
Boxer Capital Management, LLC0$00.00%−1,300,000−100.0%Sold out
5AM Venture Management, LLC0$00.00%−357,733−100.0%Sold out
Opaleye Management Inc.0$00.00%−250,933−100.0%Sold out
Marshall Wace, LLP0$00.00%−92,870−100.0%Sold out
HRT Financial LP0$00.00%−43,211−100.0%Sold out
Manufacturers Life Insurance Company, The0$00.00%−36,596−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−32,023−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−31,571−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−30,873−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−27,796−100.0%Sold out
Quadrature Capital Ltd0$00.00%−23,508−100.0%Sold out
Caption Management, LLC0$00.00%−23,376−100.0%Sold out
Oxford Asset Management LLP0$00.00%−14,473−100.0%Sold out
Mirae Asset Global ETFs Holdings Ltd.0$00.00%−14,205−100.0%Sold out
TD Asset Management Inc0$00.00%−14,000−100.0%Sold out
MetLife Investment Management0$00.00%−11,928−100.0%Sold out
Algert Global LLC0$00.00%−10,870−100.0%Sold out
OneAscent Financial Services LLC0$00.00%−10,889−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−10,590−100.0%Sold out
Scotia Capital Inc.0$00.00%−10,082−100.0%Sold out
Lazard Asset Management LLC0$00.00%−5,519−100.0%Sold out
Quest Partners LLC0$00.00%−4,220−100.0%Sold out
Natixis0$00.00%−2,669−100.0%Sold out
Coldstream Capital Management Inc0$00.00%−345−100.0%Sold out
Whittier Trust Co0$00.00%−307−100.0%Sold out
Amundi0$00.00%−256−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−175−100.0%Sold out
CoreCap Advisors, LLC0$00.00%−31−100.0%Sold out
TD Private Client Wealth LLC0$00.00%−27−100.0%Sold out
Creative Financial Designs Inc0$00.00%−16−100.0%Sold out
Avion Wealth0$00.00%−36−100.0%Sold out
Glenmede Trust Co NA––––Not filed
Lindbrook Capital, LLC––––Not filed